Drosophila melanogaster

0 known processes

unc-4 (Dmel_CG6269)

CG6269 gene product from transcript CG6269-RA

(Aliases: DPHD-1,Dunc-4,CG6269,Dmel\CG6269)

unc-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lateral inhibitionGO:00463312060.096
cell cell signaling involved in cell fate commitmentGO:00451682100.096
single organism behaviorGO:00447083910.072
neurological system processGO:00508773580.067
detection of chemical stimulus involved in sensory perceptionGO:0050907750.065
response to abiotic stimulusGO:00096283410.056
wing disc morphogenesisGO:00074723440.052
imaginal disc derived wing morphogenesisGO:00074763370.049
small molecule metabolic processGO:00442813050.046
organonitrogen compound metabolic processGO:19015643180.045
catabolic processGO:00090564090.044
organic acid metabolic processGO:00060821030.042
sensory perception of chemical stimulusGO:00076061160.042
appendage developmentGO:00487364010.041
oxoacid metabolic processGO:00434361030.041
detection of stimulus involved in sensory perceptionGO:0050906920.040
imaginal disc derived appendage developmentGO:00487373990.040
post embryonic appendage morphogenesisGO:00351203850.040
cellular amino acid metabolic processGO:0006520610.037
kidney developmentGO:000182230.037
regionalizationGO:00030024160.037
cellular protein modification processGO:00064644380.036
protein modification processGO:00362114380.036
vesicle mediated transportGO:00161923810.035
sensory perceptionGO:00076001960.035
transcription from rna polymerase ii promoterGO:00063663680.035
negative regulation of cellular metabolic processGO:00313243820.035
salivary gland morphogenesisGO:00074351450.034
defense responseGO:00069523000.034
salivary gland developmentGO:00074311620.034
cellular catabolic processGO:00442483720.034
response to external biotic stimulusGO:00432072930.034
appendage morphogenesisGO:00351073970.033
negative regulation of gene expressionGO:00106293870.033
regulation of multicellular organismal developmentGO:20000264140.033
imaginal disc derived appendage morphogenesisGO:00351143950.033
organic substance transportGO:00717022570.032
positive regulation of response to stimulusGO:00485843230.032
establishment of localization in cellGO:00516494020.032
forebrain developmentGO:003090020.032
Mouse
exocrine system developmentGO:00352721620.032
phagocytosisGO:00069092150.031
organic substance catabolic processGO:19015753080.031
carboxylic acid metabolic processGO:0019752920.031
response to other organismGO:00517072930.031
connective tissue developmentGO:006144830.031
Mouse
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.030
response to lipopolysaccharideGO:003249640.030
response to biotic stimulusGO:00096072940.030
body morphogenesisGO:001017120.030
positive regulation of cell communicationGO:00106472500.030
endocytosisGO:00068973100.030
l amino acid importGO:004309220.030
negative regulation of rna biosynthetic processGO:19026792400.030
cell deathGO:00082192790.030
immune system processGO:00023763470.029
negative regulation of response to stimulusGO:00485852580.029
regulation of cell differentiationGO:00455953020.029
Mouse
deathGO:00162652840.029
compound eye developmentGO:00487493070.029
epithelial cell differentiationGO:00308553220.029
programmed cell deathGO:00125012570.029
adult behaviorGO:00305341370.029
positive regulation of signalingGO:00230562430.029
gland morphogenesisGO:00226121450.028
gland developmentGO:00487321910.028
negative regulation of nitrogen compound metabolic processGO:00511722650.028
hormone catabolic processGO:004244730.027
cellular amine metabolic processGO:0044106120.027
detection of stimulusGO:00516061560.026
l glutamate importGO:005193810.026
positive regulation of signal transductionGO:00099672230.026
regulation of cellular amino acid metabolic processGO:000652100.026
neuropeptide signaling pathwayGO:0007218450.026
single organism catabolic processGO:00447122280.026
response to oxygen containing compoundGO:19017002000.026
sensory perception of smellGO:0007608800.026
single organism biosynthetic processGO:00447112060.026
respiratory system developmentGO:00605412130.025
amine metabolic processGO:0009308120.025
protein localizationGO:00081042840.025
sterol homeostasisGO:005509240.025
nuclear divisionGO:00002803320.025
camera type eye developmentGO:004301040.025
detection of chemical stimulusGO:0009593930.025
regulation of cellular amine metabolic processGO:003323830.025
sensory perception of salty tasteGO:005091430.025
organelle fissionGO:00482853400.024
negative regulation of nucleic acid templated transcriptionGO:19035072400.024
cellular response to dna damage stimulusGO:00069742230.024
regulation of localizationGO:00328792750.024
Worm
response to organic substanceGO:00100332840.024
developmental growthGO:00485892800.024
locomotory behaviorGO:00076261760.024
regulation of transportGO:00510491810.024
Worm
proteolysisGO:00065081920.024
positive regulation of cellular biosynthetic processGO:00313283160.024
open tracheal system developmentGO:00074242040.024
response to bacteriumGO:00096171980.023
cellular response to chemical stimulusGO:00708871990.023
negative regulation of signalingGO:00230572190.023
ethanolamine containing compound metabolic processGO:004243940.023
regulation of cell cycleGO:00517262910.023
protein complex biogenesisGO:00702712010.023
eye developmentGO:00016543230.023
segmentationGO:00352822070.023
anion homeostasisGO:005508130.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
regulation of cellular ketone metabolic processGO:001056530.023
telencephalon developmentGO:002153720.023
Mouse
carbohydrate derivative metabolic processGO:19011352170.023
regulation of transcription from rna polymerase ii promoterGO:00063573780.023
enzyme linked receptor protein signaling pathwayGO:00071671790.023
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.023
hindbrain developmentGO:003090220.023
intracellular signal transductionGO:00355563000.022
xenobiotic catabolic processGO:004217810.022
regulation of response to stressGO:00801342000.022
negative regulation of macromolecule biosynthetic processGO:00105582700.022
response to monosaccharideGO:003428440.022
negative regulation of biosynthetic processGO:00098902770.022
positive regulation of rna biosynthetic processGO:19026802660.022
defense response to other organismGO:00985422250.022
dendrite developmentGO:00163582040.022
negative regulation of transcription dna templatedGO:00458922370.021
negative regulation of nucleobase containing compound metabolic processGO:00459342610.021
kidney epithelium developmentGO:007207330.021
compound eye morphogenesisGO:00017452490.021
regulation of multi organism processGO:00439001310.021
nephron developmentGO:007200630.021
immune response regulating signaling pathwayGO:000276420.021
salt aversionGO:003519930.021
positive regulation of biosynthetic processGO:00098913160.021
positive regulation of cell migrationGO:003033520.021
cell divisionGO:00513012480.021
kidney morphogenesisGO:006099330.021
dorsal ventral pattern formationGO:00099531330.021
positive regulation of macromolecule metabolic processGO:00106044050.021
columnar cuboidal epithelial cell differentiationGO:00020652560.021
negative regulation of rna metabolic processGO:00512532510.021
macromolecular complex assemblyGO:00650032560.021
developmental programmed cell deathGO:00106231380.021
columnar cuboidal epithelial cell developmentGO:00020662490.021
nephron epithelium developmentGO:007200930.021
spermatogenesisGO:00072832000.021
response to organophosphorusGO:004668320.021
multi organism behaviorGO:00517051750.021
phosphorylationGO:00163102940.020
regulation of molecular functionGO:00650092170.020
intracellular transportGO:00469072280.020
g protein coupled receptor signaling pathwayGO:00071861360.020
chromosome organizationGO:00512763600.020
steroid catabolic processGO:000670610.020
cellular ketone metabolic processGO:0042180240.020
matingGO:00076181200.020
axon developmentGO:00615642970.020
dendrite morphogenesisGO:00488131990.020
negative regulation of cellular biosynthetic processGO:00313272770.020
acylglycerol catabolic processGO:004646430.020
regulation of mitotic cell cycleGO:00073461900.019
positive regulation of nucleic acid templated transcriptionGO:19035082660.019
regulation of nervous system developmentGO:00519602480.019
phosphatidylethanolamine metabolic processGO:004633710.019
taxisGO:00423303040.019
tissue deathGO:00162711020.019
nephron morphogenesisGO:007202830.019
regulation of immune system processGO:00026821760.019
behavioral response to painGO:004826630.019
triglyceride biosynthetic processGO:001943220.019
regulation of cellular protein metabolic processGO:00322682430.019
macromolecule catabolic processGO:00090571610.019
sensory organ morphogenesisGO:00905962600.019
nephron tubule morphogenesisGO:007207830.019
negative regulation of developmental processGO:00510932010.019
immune responseGO:00069552460.019
triglyceride catabolic processGO:001943330.019
nephron tubule developmentGO:007208030.019
benzene containing compound metabolic processGO:004253730.019
response to nutrient levelsGO:00316671140.018
positive regulation of cell motilityGO:200014730.018
regulation of protein metabolic processGO:00512462560.018
positive regulation of macromolecule biosynthetic processGO:00105572830.018
pigment metabolic processGO:0042440840.018
homeostatic processGO:00425921990.018
histolysisGO:00075591020.018
sulfur compound metabolic processGO:0006790590.018
negative regulation of signal transductionGO:00099682060.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
cholesterol homeostasisGO:004263230.018
actin filament organizationGO:00070151260.018
hematopoietic progenitor cell differentiationGO:000224410.018
response to extracellular stimulusGO:00099911160.018
estrogen metabolic processGO:000821010.018
response to hexoseGO:000974630.018
regulation of gene expression epigeneticGO:00400291280.018
protein complex assemblyGO:00064612000.018
cell proliferationGO:00082832990.018
Mouse
regulation of anatomical structure morphogenesisGO:00226032420.018
regulation of intracellular signal transductionGO:19025312360.018
mesenchymal cell differentiationGO:004876210.018
growthGO:00400073590.018
positive regulation of gene expressionGO:00106282900.017
single organism intracellular transportGO:19025822070.017
ion transportGO:00068111450.017
regulation of cell developmentGO:00602842150.017
cellular amide metabolic processGO:0043603800.017
compound eye photoreceptor cell differentiationGO:00017511400.017
adult locomotory behaviorGO:0008344760.017
protein heterooligomerizationGO:005129140.017
cellular macromolecule catabolic processGO:00442651360.017
salivary gland cell autophagic cell deathGO:0035071830.017
positive regulation of nucleobase containing compound metabolic processGO:00459353320.017
phospholipid homeostasisGO:005509110.017
monocarboxylic acid transportGO:001571830.017
embryonic pattern specificationGO:00098801740.017
localization of cellGO:00516742570.017
regulation of phosphorus metabolic processGO:00511742100.017
cellular component assembly involved in morphogenesisGO:00109271510.017
regulation of cellular catabolic processGO:00313291570.017
cell motilityGO:00488702510.017
response to painGO:004826530.017
negative regulation of cell communicationGO:00106482230.017
response to temperature stimulusGO:00092661060.017
tissue morphogenesisGO:00487292970.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of cell cycle processGO:00105641810.017
positive regulation of rna metabolic processGO:00512542710.017
regulation of catalytic activityGO:00507901850.017
response to alcoholGO:0097305950.017
glycerolipid catabolic processGO:004650330.017
regulation of epithelial cell proliferationGO:005067840.017
photoreceptor cell differentiationGO:00465301700.017
biological adhesionGO:00226101380.017
male gamete generationGO:00482322010.016
eggshell formationGO:00307031050.016
chemotaxisGO:00069352490.016
negative regulation of cell differentiationGO:00455961430.016
regulation of sequestering of triglycerideGO:001088930.016
regulation of phosphate metabolic processGO:00192202100.016
mesenchymal cell developmentGO:001403110.016
response to glucoseGO:000974920.016
inter male aggressive behaviorGO:0002121600.016
single organism cellular localizationGO:19025801800.016
morphogenesis of an epitheliumGO:00020092760.016
aromatic compound catabolic processGO:00194391660.016
synaptic transmissionGO:00072682880.016
autophagic cell deathGO:0048102830.016
blastoderm segmentationGO:00073501590.016
androgen metabolic processGO:000820910.016
mesoderm developmentGO:0007498780.016
apoptotic processGO:00069151590.016
spindle organizationGO:00070512530.016
salivary gland histolysisGO:0035070880.016
positive regulation of molecular functionGO:00440931360.016
response to starvationGO:0042594970.016
response to copper ionGO:004668840.016
rna processingGO:00063961470.016
neuron projection guidanceGO:00974852410.016
lipid metabolic processGO:00066291210.016
immune effector processGO:0002252980.016
positive regulation of phosphate metabolic processGO:00459371390.016
tube developmentGO:00352952440.016
secondary metabolic processGO:0019748750.016
heterocycle catabolic processGO:00467001660.016
gene silencingGO:00164581380.016
immune response activating signal transductionGO:000275720.015
organic cyclic compound catabolic processGO:19013611680.015
regulation of cellular component biogenesisGO:00440872010.015
positive regulation of transcription dna templatedGO:00458932660.015
notch signaling pathwayGO:00072191200.015
axis specificationGO:00097981670.015
ras protein signal transductionGO:0007265880.015
axonogenesisGO:00074092900.015
vitamin biosynthetic processGO:000911010.015
innate immune responseGO:00450871440.015
small gtpase mediated signal transductionGO:0007264880.015
cellular response to ethanolGO:007136140.015
molting cycle chitin based cuticleGO:0007591560.015
response to endogenous stimulusGO:00097191190.015
cell adhesionGO:00071551360.015
actin filament based processGO:00300292200.015
cellular macromolecule localizationGO:00707272200.015
actin cytoskeleton organizationGO:00300362060.015
defense response to bacteriumGO:00427421780.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
regulation of mitotic cell cycle phase transitionGO:19019901300.015
positive regulation of multicellular organismal processGO:00512401430.015
Worm
organophosphate metabolic processGO:00196371950.015
cellular response to molecule of bacterial originGO:007121930.015
regulation of i kappab kinase nf kappab signalingGO:004312220.015
epithelial cell developmentGO:00020642740.015
neutral lipid catabolic processGO:004646130.015
eye morphogenesisGO:00485922600.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.015
synapse assemblyGO:00074161430.015
pigmentationGO:0043473750.015
ovarian follicle cell developmentGO:00307072480.015
cell migrationGO:00164772380.015
chromatin organizationGO:00063252070.015
tube morphogenesisGO:00352391910.015
cellular lipid metabolic processGO:0044255830.015
chromatin modificationGO:00165681470.015
regulation of catabolic processGO:00098941700.015
cellular response to lipopolysaccharideGO:007122230.015
regulation of notch signaling pathwayGO:00085931000.015
regulation of immune responseGO:00507761180.015
regulation of cell cycle phase transitionGO:19019871300.014
eye photoreceptor cell differentiationGO:00017541450.014
positive regulation of developmental processGO:00510941430.014
response to radiationGO:00093141550.014
anterior posterior pattern specificationGO:00099521360.014
cellular nitrogen compound catabolic processGO:00442701650.014
imaginal disc pattern formationGO:0007447910.014
agingGO:00075681430.014
developmental pigmentationGO:0048066680.014
dorsal ventral axis specificationGO:0009950660.014
peptidyl amino acid modificationGO:00181931050.014
drinking behaviorGO:004275620.014
fat soluble vitamin metabolic processGO:000677510.014
mitotic spindle organizationGO:00070522200.014
organonitrogen compound biosynthetic processGO:19015661170.014
positive regulation of immune system processGO:0002684680.014
limb developmentGO:006017310.014
cellular response to organic substanceGO:00713101320.014
positive regulation of phosphorus metabolic processGO:00105621390.014
positive regulation of transportGO:0051050920.014
Worm
nucleobase containing compound catabolic processGO:00346551650.014
neurotransmitter metabolic processGO:004213320.014
cranial nerve developmentGO:002154510.014
phosphate ion transportGO:000681740.014
axon guidanceGO:00074112330.014
cholesterol transportGO:003030120.014
autophagyGO:00069141080.014
transmembrane transportGO:00550851390.014
mitotic dna integrity checkpointGO:0044774750.014
chromosome segregationGO:00070591570.014
positive regulation of lipid storageGO:001088440.014
regulation of developmental growthGO:00486381740.014
head developmentGO:00603221350.014
Mouse
regulation of cell substrate adhesionGO:001081020.014
antimicrobial humoral responseGO:0019730990.014
peripheral nervous system developmentGO:0007422520.014
carbohydrate derivative biosynthetic processGO:1901137850.014
imaginal disc derived wing margin morphogenesisGO:0008587410.014
regulation of organelle organizationGO:00330431960.014
mapk cascadeGO:00001651070.014
pattern recognition receptor signaling pathwayGO:000222120.014
protein hydroxylationGO:001812610.014
cytokinesisGO:0000910900.014
activation of innate immune responseGO:000221840.014
negative regulation of nervous system developmentGO:0051961920.014
organelle assemblyGO:00709251980.014
multicellular organismal agingGO:00102591400.014
aggressive behaviorGO:0002118630.014
posttranscriptional regulation of gene expressionGO:00106081450.014
cytoplasmic transportGO:00164821300.013
vitamin metabolic processGO:000676620.013
developmental maturationGO:00217001720.013
protein phosphorylationGO:00064681690.013
central nervous system developmentGO:00074172010.013
Mouse
apoptotic process involved in morphogenesisGO:006056130.013
protein maturationGO:0051604710.013
regulation of lipid transportGO:003236830.013
regulation of heart morphogenesisGO:200082630.013
dna metabolic processGO:00062592270.013
lipopolysaccharide mediated signaling pathwayGO:003166310.013
protein transportGO:00150311550.013
anterior posterior axis specificationGO:00099481090.013
sodium dependent phosphate transportGO:004434120.013
humoral immune responseGO:00069591170.013
polyol biosynthetic processGO:004617330.013
regulation of epithelial cell differentiationGO:003085640.013
medium chain fatty acid metabolic processGO:005179110.013
mitotic nuclear divisionGO:00070672130.013
acylglycerol biosynthetic processGO:004646320.013
nucleobase containing small molecule metabolic processGO:00550861740.013
mitotic cell cycle phase transitionGO:00447721380.013
limb morphogenesisGO:003510810.013
positive regulation of catalytic activityGO:00430851180.013
retina development in camera type eyeGO:006004140.013
regulation of cell proliferationGO:00421271630.013
digestive tract developmentGO:00485651490.013
g2 dna damage checkpointGO:0031572690.013
regulation of cell deathGO:00109411730.013
defense response to gram negative bacteriumGO:0050829940.013
stem cell differentiationGO:00488631170.013
regulation of programmed cell deathGO:00430671520.013
response to organic cyclic compoundGO:0014070890.013
reproductive behaviorGO:00190981220.013
negative regulation of cell cycle processGO:00109481090.013
regulation of cellular localizationGO:00603411360.013
ion transmembrane transportGO:00342201220.013
positive regulation of intracellular signal transductionGO:19025331160.013
nucleoside phosphate metabolic processGO:00067531620.013
hair cell differentiationGO:0035315470.013
phosphatidic acid metabolic processGO:004647310.013
embryonic morphogenesisGO:00485982060.013
mitotic g2 m transition checkpointGO:0044818700.013
chorion containing eggshell formationGO:00073041050.013
cell cycle phase transitionGO:00447701400.013
response to heatGO:0009408630.013
water homeostasisGO:003010430.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.013
cellular response to biotic stimulusGO:007121640.013
response to mercury ionGO:004668930.013
organophosphate catabolic processGO:00464341120.013
male mating behaviorGO:0060179700.013
regulation of anatomical structure sizeGO:00900661630.013
camera type eye morphogenesisGO:004859320.013
fat soluble vitamin biosynthetic processGO:004236210.012
rna localizationGO:00064031150.012
wing disc pattern formationGO:0035222660.012
regulation of defense responseGO:00313471020.012
cell recognitionGO:00080371020.012
positive regulation of i kappab kinase nf kappab signalingGO:004312310.012
pigment metabolic process involved in pigmentationGO:0043474330.012
nitrogen compound transportGO:0071705850.012
cellular response to hexose stimulusGO:007133110.012
oxidoreduction coenzyme metabolic processGO:000673320.012
negative regulation of cell cycle phase transitionGO:19019881030.012
nephron epithelium morphogenesisGO:007208830.012
positive regulation of sequestering of triglycerideGO:001089010.012
positive regulation of response to external stimulusGO:0032103440.012
neuron recognitionGO:00080381010.012
multi organism reproductive behaviorGO:00447051210.012
signal transduction by phosphorylationGO:00230141070.012
innate immune response activating signal transductionGO:000275820.012
regulation of growthGO:00400082330.012
carbohydrate metabolic processGO:0005975820.012
imaginal disc derived wing vein specificationGO:0007474480.012
regulation of erbb signaling pathwayGO:1901184420.012
purine nucleotide metabolic processGO:00061631460.012
purine containing compound metabolic processGO:00725211550.012
positive regulation of immune responseGO:0050778630.012
negative regulation of cell cycleGO:00457861160.012
response to oxidative stressGO:0006979860.012
regulation of phosphorylationGO:00423251470.012
regulation of sterol transportGO:003237110.012
photoreceptor cell developmentGO:0042461960.012
sensory perception of painGO:001923340.012
secretionGO:00469031090.012
Worm
mitotic cell cycle checkpointGO:0007093880.012
negative regulation of protein metabolic processGO:0051248850.012
eye photoreceptor cell developmentGO:0042462810.012
determination of adult lifespanGO:00083401370.012
alditol phosphate metabolic processGO:005264620.012
neutral lipid biosynthetic processGO:004646020.012
peptide metabolic processGO:0006518800.012
protein processingGO:0016485680.012
anterior posterior axis specification embryoGO:00085951030.012
cellular macromolecular complex assemblyGO:00346221530.012
maintenance of locationGO:0051235730.012
peptidyl lysine modificationGO:0018205570.012
purine ribonucleotide metabolic processGO:00091501450.012
synaptic growth at neuromuscular junctionGO:00511241190.012
tripartite regional subdivisionGO:00073511030.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
mitotic g2 dna damage checkpointGO:0007095690.012
regulation of apoptotic processGO:00429811300.012
anatomical structure homeostasisGO:0060249970.012
negative regulation of cellular protein metabolic processGO:0032269850.012
positive regulation of protein metabolic processGO:00512471280.012
single organism carbohydrate metabolic processGO:0044723720.012
digestive tract morphogenesisGO:00485461270.012
organonitrogen compound catabolic processGO:19015651280.012
embryonic axis specificationGO:00005781070.012

unc-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.070
disease of metabolismDOID:001466700.024
inherited metabolic disorderDOID:65500.022
nervous system diseaseDOID:86300.022
acquired metabolic diseaseDOID:006015800.021
diabetes mellitusDOID:935100.020
glucose metabolism diseaseDOID:419400.020
carbohydrate metabolism diseaseDOID:005001300.020
type 2 diabetes mellitusDOID:935200.020
musculoskeletal system diseaseDOID:1700.019
urinary system diseaseDOID:1800.016
disease of cellular proliferationDOID:1456600.015
renal tubular transport diseaseDOID:44700.015
kidney diseaseDOID:55700.015
cancerDOID:16200.015
bone diseaseDOID:008000100.015
connective tissue diseaseDOID:6500.015
cardiovascular system diseaseDOID:128700.014
vascular diseaseDOID:17800.014
artery diseaseDOID:005082800.013
hypertensionDOID:1076300.013
sensory system diseaseDOID:005015500.012
hypotrichosisDOID:453500.012
hair diseaseDOID:42100.012
integumentary system diseaseDOID:1600.012
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012
lipid metabolism disorderDOID:314600.012
familial hypertriglyceridemiaDOID:005052700.012