Drosophila melanogaster

33 known processes

Best1 (Dmel_CG6264)

Bestrophin 1

(Aliases: anon-WO0118547.380,Dmel\CG6264,Dbest,dmBest1,CG6264,dbest1,best)

Best1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transportGO:00510491810.128
regulation of localizationGO:00328792750.102
organonitrogen compound metabolic processGO:19015643180.091
organic substance transportGO:00717022570.080
programmed cell deathGO:00125012570.071
establishment of localization in cellGO:00516494020.071
regionalizationGO:00030024160.070
single organism biosynthetic processGO:00447112060.069
small molecule metabolic processGO:00442813050.068
deathGO:00162652840.066
response to abiotic stimulusGO:00096283410.061
response to bacteriumGO:00096171980.058
taxisGO:00423303040.057
post embryonic appendage morphogenesisGO:00351203850.056
negative regulation of cell communicationGO:00106482230.055
negative regulation of signalingGO:00230572190.052
nucleobase containing small molecule metabolic processGO:00550861740.052
imaginal disc derived wing morphogenesisGO:00074763370.050
positive regulation of nitrogen compound metabolic processGO:00511733540.049
single organism catabolic processGO:00447122280.049
cell deathGO:00082192790.049
cellular protein modification processGO:00064644380.047
protein modification processGO:00362114380.047
negative regulation of signal transductionGO:00099682060.047
regulation of phosphorus metabolic processGO:00511742100.046
organic acid metabolic processGO:00060821030.046
imaginal disc derived appendage developmentGO:00487373990.046
protein localizationGO:00081042840.045
response to biotic stimulusGO:00096072940.045
response to lipopolysaccharideGO:003249640.045
growthGO:00400073590.044
cellular amine metabolic processGO:0044106120.044
endocytosisGO:00068973100.043
homeostatic processGO:00425921990.043
epithelial cell differentiationGO:00308553220.042
regulation of cellular amine metabolic processGO:003323830.042
intracellular signal transductionGO:00355563000.041
regulation of multicellular organismal developmentGO:20000264140.039
endomembrane system organizationGO:00102561190.038
glycosyl compound catabolic processGO:19016581120.038
nucleoside phosphate metabolic processGO:00067531620.037
single organism behaviorGO:00447083910.037
regulation of catalytic activityGO:00507901850.037
organophosphate metabolic processGO:00196371950.036
small gtpase mediated signal transductionGO:0007264880.036
cellular amino acid metabolic processGO:0006520610.036
defense response to other organismGO:00985422250.036
regulation of intracellular signal transductionGO:19025312360.035
carboxylic acid metabolic processGO:0019752920.035
cation transmembrane transportGO:0098655880.035
regulation of apoptotic processGO:00429811300.035
wing disc morphogenesisGO:00074723440.035
positive regulation of phosphate metabolic processGO:00459371390.034
exocrine system developmentGO:00352721620.034
vesicle mediated transportGO:00161923810.034
synaptic transmissionGO:00072682880.034
cation transportGO:00068121100.033
amine metabolic processGO:0009308120.033
detection of stimulusGO:00516061560.033
regulation of phosphate metabolic processGO:00192202100.033
positive regulation of signalingGO:00230562430.033
appendage developmentGO:00487364010.033
salivary gland developmentGO:00074311620.032
ion transmembrane transportGO:00342201220.032
regulation of cellular component biogenesisGO:00440872010.032
negative regulation of response to stimulusGO:00485852580.032
apoptotic processGO:00069151590.031
regulation of cellular ketone metabolic processGO:001056530.031
aromatic compound catabolic processGO:00194391660.031
ameboidal type cell migrationGO:00016671510.031
positive regulation of phosphorus metabolic processGO:00105621390.030
imaginal disc derived appendage morphogenesisGO:00351143950.030
regulation of cellular amino acid metabolic processGO:000652100.030
single organism membrane organizationGO:0044802930.030
localization of cellGO:00516742570.030
cytoplasmic transportGO:00164821300.029
autophagic cell deathGO:0048102830.029
regulation of protein metabolic processGO:00512462560.029
transmembrane transportGO:00550851390.029
ribonucleoside triphosphate metabolic processGO:00091991190.029
nucleobase containing compound catabolic processGO:00346551650.029
purine ribonucleotide catabolic processGO:00091541090.028
nucleoside triphosphate metabolic processGO:00091411200.028
response to hexoseGO:000974630.028
phosphorylationGO:00163102940.028
positive regulation of multicellular organismal processGO:00512401430.028
single organism intracellular transportGO:19025822070.028
tissue deathGO:00162711020.028
gtp metabolic processGO:0046039720.027
cellular catabolic processGO:00442483720.027
positive regulation of response to stimulusGO:00485843230.027
defense responseGO:00069523000.027
carbohydrate derivative metabolic processGO:19011352170.027
epidermal growth factor receptor signaling pathwayGO:0007173580.027
lipid metabolic processGO:00066291210.027
appendage morphogenesisGO:00351073970.027
response to oxygen containing compoundGO:19017002000.026
cellular macromolecule localizationGO:00707272200.026
response to other organismGO:00517072930.026
regulation of hydrolase activityGO:0051336970.026
ribose phosphate metabolic processGO:00196931450.026
positive regulation of cell communicationGO:00106472500.026
regulation of cell developmentGO:00602842150.026
nitrogen compound transportGO:0071705850.026
cellular response to lipopolysaccharideGO:007122230.026
regulation of molecular functionGO:00650092170.026
purine ribonucleoside triphosphate catabolic processGO:00092071080.026
positive regulation of biosynthetic processGO:00098913160.025
positive regulation of catalytic activityGO:00430851180.025
oxoacid metabolic processGO:00434361030.025
membrane organizationGO:00610241120.025
heterocycle catabolic processGO:00467001660.025
purine ribonucleoside triphosphate metabolic processGO:00092051190.025
ion transportGO:00068111450.025
cellular ketone metabolic processGO:0042180240.025
organic cyclic compound catabolic processGO:19013611680.025
tissue morphogenesisGO:00487292970.024
epithelial cell developmentGO:00020642740.024
positive regulation of gtpase activityGO:0043547430.024
positive regulation of molecular functionGO:00440931360.024
ribonucleotide catabolic processGO:00092611090.024
protein transportGO:00150311550.024
purine containing compound metabolic processGO:00725211550.024
single organism cellular localizationGO:19025801800.024
regulation of cell differentiationGO:00455953020.024
ribonucleoside triphosphate catabolic processGO:00092031080.024
ribonucleoside catabolic processGO:00424541120.024
immune response regulating cell surface receptor signaling pathway involved in phagocytosisGO:000243330.024
columnar cuboidal epithelial cell differentiationGO:00020652560.024
protein phosphorylationGO:00064681690.024
ribonucleotide metabolic processGO:00092591450.024
phagocytosis recognitionGO:000691010.024
regulation of erbb signaling pathwayGO:1901184420.023
purine nucleotide metabolic processGO:00061631460.023
gland morphogenesisGO:00226121450.023
phagocytosisGO:00069092150.023
salivary gland morphogenesisGO:00074351450.023
response to organic substanceGO:00100332840.023
organic substance catabolic processGO:19015753080.023
positive regulation of signal transductionGO:00099672230.023
salivary gland histolysisGO:0035070880.023
regulation of cellular protein metabolic processGO:00322682430.022
ras protein signal transductionGO:0007265880.022
purine ribonucleoside metabolic processGO:00461281270.022
positive regulation of cellular biosynthetic processGO:00313283160.022
purine nucleoside triphosphate metabolic processGO:00091441190.022
skin developmentGO:0043588650.022
response to radiationGO:00093141550.022
purine nucleoside catabolic processGO:00061521120.022
developmental programmed cell deathGO:00106231380.022
glycosyl compound metabolic processGO:19016571270.022
purine nucleotide catabolic processGO:00061951090.022
catabolic processGO:00090564090.022
response to external biotic stimulusGO:00432072930.021
purine ribonucleotide metabolic processGO:00091501450.021
negative regulation of cellular metabolic processGO:00313243820.021
organonitrogen compound catabolic processGO:19015651280.021
positive regulation of nervous system developmentGO:0051962690.021
detection of chemical stimulusGO:0009593930.021
compound eye developmentGO:00487493070.021
spermatid developmentGO:0007286980.021
nucleoside phosphate catabolic processGO:19012921100.021
regulation of gtp catabolic processGO:0033124440.021
purine containing compound catabolic processGO:00725231120.021
enzyme linked receptor protein signaling pathwayGO:00071671790.021
positive regulation of purine nucleotide metabolic processGO:1900544550.021
positive regulation of ras gtpase activityGO:0032320360.021
regulation of anatomical structure morphogenesisGO:00226032420.021
negative regulation of erbb signaling pathwayGO:1901185290.021
chemical homeostasisGO:0048878920.021
cell proliferationGO:00082832990.020
nucleoside catabolic processGO:00091641120.020
purine nucleoside triphosphate catabolic processGO:00091461080.020
gland developmentGO:00487321910.020
nucleotide metabolic processGO:00091171610.020
carbohydrate derivative catabolic processGO:19011361180.020
positive regulation of nucleotide metabolic processGO:0045981550.020
dna metabolic processGO:00062592270.020
columnar cuboidal epithelial cell developmentGO:00020662490.020
cell motilityGO:00488702510.020
gtp catabolic processGO:0006184720.020
sensory organ morphogenesisGO:00905962600.020
cellular response to molecule of bacterial originGO:007121930.020
rna localizationGO:00064031150.020
inorganic cation transmembrane transportGO:0098662610.020
histolysisGO:00075591020.019
defense response to bacteriumGO:00427421780.019
chemotaxisGO:00069352490.019
purine ribonucleoside catabolic processGO:00461301120.019
regulation of cellular localizationGO:00603411360.019
establishment of protein localizationGO:00451841630.019
epithelium migrationGO:00901321480.019
cellular response to chemical stimulusGO:00708871990.019
monocarboxylic acid transportGO:001571830.019
intracellular protein transportGO:00068861040.019
axonogenesisGO:00074092900.019
actin cytoskeleton organizationGO:00300362060.019
regulation of nucleotide metabolic processGO:0006140620.018
immune system processGO:00023763470.018
salivary gland cell autophagic cell deathGO:0035071830.018
compound eye photoreceptor cell differentiationGO:00017511400.018
cell divisionGO:00513012480.018
positive regulation of hydrolase activityGO:0051345780.018
purine nucleoside metabolic processGO:00422781270.018
ribonucleoside metabolic processGO:00091191270.018
cognitionGO:00508901410.017
organophosphate catabolic processGO:00464341120.017
regulation of nucleotide catabolic processGO:0030811480.017
cellular nitrogen compound catabolic processGO:00442701650.017
positive regulation of nucleobase containing compound metabolic processGO:00459353320.017
central nervous system developmentGO:00074172010.017
immune response activating signal transductionGO:000275720.017
negative regulation of nitrogen compound metabolic processGO:00511722650.017
l amino acid importGO:004309220.017
cholesterol transportGO:003030120.016
biological adhesionGO:00226101380.016
regulation of small gtpase mediated signal transductionGO:0051056930.016
cell adhesionGO:00071551360.016
positive regulation of developmental processGO:00510941430.016
body morphogenesisGO:001017120.016
regulation of nucleoside metabolic processGO:0009118500.016
regulation of neurogenesisGO:00507671580.016
response to light stimulusGO:00094161240.016
neuron projection guidanceGO:00974852410.016
ovarian follicle cell developmentGO:00307072480.016
negative regulation of biosynthetic processGO:00098902770.016
regulation of neuron differentiationGO:00456641030.016
forebrain developmentGO:003090020.016
nucleoside metabolic processGO:00091161270.015
positive regulation of macromolecule biosynthetic processGO:00105572830.015
positive regulation of cell migrationGO:003033520.015
positive regulation of transportGO:0051050920.015
cell recognitionGO:00080371020.015
positive regulation of macromolecule metabolic processGO:00106044050.015
regulation of nervous system developmentGO:00519602480.015
axis specificationGO:00097981670.015
eggshell formationGO:00307031050.015
tissue migrationGO:00901301550.015
organelle localizationGO:00516401480.015
lipid localizationGO:0010876540.015
immune response regulating signaling pathwayGO:000276420.015
neurological system processGO:00508773580.015
nucleotide catabolic processGO:00091661090.015
axon guidanceGO:00074112330.015
nucleoside triphosphate catabolic processGO:00091431080.015
compound eye morphogenesisGO:00017452490.015
negative regulation of epithelial cell proliferationGO:005068040.015
regulation of protein modification processGO:00313991120.014
regulation of protein localizationGO:0032880760.014
regulation of epithelial cell proliferationGO:005067840.014
hindbrain developmentGO:003090220.014
regulation of ras gtpase activityGO:0032318380.014
regulation of ion transportGO:0043269390.014
eye developmentGO:00016543230.014
meiotic cell cycle processGO:19030461320.014
cellular lipid metabolic processGO:0044255830.014
purine ribonucleoside monophosphate metabolic processGO:0009167500.014
learning or memoryGO:00076111410.014
negative regulation of developmental processGO:00510932010.014
segmentationGO:00352822070.014
positive regulation of cell developmentGO:0010720610.014
positive regulation of cellular catabolic processGO:0031331950.014
metal ion transportGO:0030001740.014
chaeta developmentGO:0022416970.014
cytokinesisGO:0000910900.014
positive regulation of nucleoside metabolic processGO:0045979470.014
peptide metabolic processGO:0006518800.013
divalent inorganic cation transportGO:0072511300.013
regulation of ras protein signal transductionGO:0046578930.013
guanosine containing compound catabolic processGO:1901069740.013
anion transportGO:0006820410.013
regulation of protein phosphorylationGO:0001932640.013
regulation of purine nucleotide metabolic processGO:1900542620.013
regulation of growthGO:00400082330.013
negative regulation of cellular biosynthetic processGO:00313272770.013
plasma membrane organizationGO:0007009260.013
regulation of gtpase activityGO:0043087440.013
dorsal appendage formationGO:0046843470.013
negative regulation of cellular protein metabolic processGO:0032269850.013
synapse organizationGO:00508081960.013
establishment of rna localizationGO:0051236470.013
eye pigmentationGO:0048069430.013
immune responseGO:00069552460.013
innate immune responseGO:00450871440.013
regulation of cell deathGO:00109411730.013
response to monosaccharideGO:003428440.013
positive regulation of rna metabolic processGO:00512542710.013
mrna metabolic processGO:00160711240.012
intracellular transportGO:00469072280.012
centrosome organizationGO:00512971630.012
chromosome organizationGO:00512763600.012
sterol homeostasisGO:005509240.012
regulation of synapse assemblyGO:0051963940.012
photoreceptor cell differentiationGO:00465301700.012
cellular protein localizationGO:00346131600.012
neuron recognitionGO:00080381010.012
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.012
regulation of cell projection organizationGO:0031344920.012
immune effector processGO:0002252980.012
glutathione metabolic processGO:0006749370.012
epithelial cell migrationGO:00106311480.012
acid secretionGO:004671710.012
ethanolamine containing compound metabolic processGO:004243940.012
lipopolysaccharide mediated signaling pathwayGO:003166310.012
positive regulation of cell motilityGO:200014730.012
regulation of catabolic processGO:00098941700.012
regulation of vesicle mediated transportGO:0060627590.012
guanosine containing compound metabolic processGO:1901068740.012
epidermis developmentGO:0008544650.012
dendrite morphogenesisGO:00488131990.012
memoryGO:0007613940.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.012
erbb signaling pathwayGO:0038127580.012
positive regulation of cellular component biogenesisGO:0044089800.011
wound healingGO:0042060750.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
regulation of cellular response to stressGO:0080135890.011
head developmentGO:00603221350.011
peptidyl amino acid modificationGO:00181931050.011
inorganic ion transmembrane transportGO:0098660730.011
regulation of establishment of protein localizationGO:0070201610.011
positive regulation of purine nucleotide catabolic processGO:0033123460.011
positive regulation of intracellular signal transductionGO:19025331160.011
medium chain fatty acid metabolic processGO:005179110.011
cellular response to organic substanceGO:00713101320.011
positive regulation of gene expressionGO:00106282900.011
regulation of programmed cell deathGO:00430671520.011
negative regulation of rna biosynthetic processGO:19026792400.011
regulation of intracellular protein transportGO:0033157460.011
chorion containing eggshell formationGO:00073041050.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
olfactory behaviorGO:0042048970.011
sulfur compound metabolic processGO:0006790590.011
developmental growthGO:00485892800.011
regulation of actin filament based processGO:0032970420.011
secretionGO:00469031090.011
regulation of lipid transportGO:003236830.011
negative regulation of rna metabolic processGO:00512532510.011
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.011
negative regulation of gene expressionGO:00106293870.011
notch signaling pathwayGO:00072191200.010
positive regulation of neurogenesisGO:0050769410.010
cell migrationGO:00164772380.010
positive regulation of rna biosynthetic processGO:19026802660.010
regulation of developmental growthGO:00486381740.010
camera type eye developmentGO:004301040.010
response to glucoseGO:000974920.010
nucleocytoplasmic transportGO:0006913720.010
telencephalon developmentGO:002153720.010
positive regulation of immune responseGO:0050778630.010
cholesterol homeostasisGO:004263230.010
cellular response to biotic stimulusGO:007121640.010
regulation of purine nucleotide catabolic processGO:0033121480.010
cellular component disassemblyGO:0022411460.010
establishment or maintenance of cell polarityGO:00071631670.010

Best1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
Human
nervous system diseaseDOID:86300.025
Human
central nervous system diseaseDOID:33100.016
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011