Drosophila melanogaster

0 known processes

Nep5 (Dmel_CG6265)

Neprilysin 5

(Aliases: Dmel\CG6265,DmeNEP5,CG6265)

Nep5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory perceptionGO:00076001960.145
neurological system processGO:00508773580.102
regionalizationGO:00030024160.069
positive regulation of nucleobase containing compound metabolic processGO:00459353320.069
response to external biotic stimulusGO:00432072930.068
positive regulation of cellular biosynthetic processGO:00313283160.067
single organism behaviorGO:00447083910.065
positive regulation of rna biosynthetic processGO:19026802660.064
positive regulation of macromolecule biosynthetic processGO:00105572830.062
positive regulation of response to stimulusGO:00485843230.060
establishment of localization in cellGO:00516494020.057
regulation of transcription from rna polymerase ii promoterGO:00063573780.056
negative regulation of gene expressionGO:00106293870.055
positive regulation of biosynthetic processGO:00098913160.055
positive regulation of rna metabolic processGO:00512542710.055
multi multicellular organism processGO:00447061230.053
Fly
transcription from rna polymerase ii promoterGO:00063663680.052
positive regulation of macromolecule metabolic processGO:00106044050.052
multi organism behaviorGO:00517051750.051
Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.051
organonitrogen compound metabolic processGO:19015643180.050
taxisGO:00423303040.050
sensory perception of chemical stimulusGO:00076061160.050
positive regulation of transcription dna templatedGO:00458932660.048
response to biotic stimulusGO:00096072940.047
response to abiotic stimulusGO:00096283410.047
response to other organismGO:00517072930.046
negative regulation of cellular metabolic processGO:00313243820.046
negative regulation of nitrogen compound metabolic processGO:00511722650.046
immune system processGO:00023763470.045
catabolic processGO:00090564090.045
locomotory behaviorGO:00076261760.045
defense responseGO:00069523000.044
regulation of multicellular organismal developmentGO:20000264140.044
intracellular signal transductionGO:00355563000.044
positive regulation of cell communicationGO:00106472500.043
organelle fissionGO:00482853400.043
phosphorylationGO:00163102940.043
negative regulation of response to stimulusGO:00485852580.043
response to light stimulusGO:00094161240.043
localization of cellGO:00516742570.043
small molecule metabolic processGO:00442813050.043
cellular protein modification processGO:00064644380.042
detection of stimulusGO:00516061560.042
forebrain developmentGO:003090020.041
protein modification processGO:00362114380.041
eye morphogenesisGO:00485922600.041
Fly
sensory organ morphogenesisGO:00905962600.041
Fly
regulation of cell differentiationGO:00455953020.040
response to organic substanceGO:00100332840.039
positive regulation of signalingGO:00230562430.039
regulation of localizationGO:00328792750.039
positive regulation of gene expressionGO:00106282900.039
endocytosisGO:00068973100.038
ion transportGO:00068111450.038
cellular catabolic processGO:00442483720.038
organic substance transportGO:00717022570.037
cell migrationGO:00164772380.037
vesicle mediated transportGO:00161923810.037
detection of stimulus involved in sensory perceptionGO:0050906920.037
organic substance catabolic processGO:19015753080.037
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.037
negative regulation of cellular biosynthetic processGO:00313272770.036
negative regulation of transcription dna templatedGO:00458922370.036
positive regulation of signal transductionGO:00099672230.035
nuclear divisionGO:00002803320.034
eye developmentGO:00016543230.034
Fly
morphogenesis of an epitheliumGO:00020092760.034
appendage morphogenesisGO:00351073970.034
positive regulation of nucleic acid templated transcriptionGO:19035082660.034
regulation of intracellular signal transductionGO:19025312360.033
imaginal disc derived appendage morphogenesisGO:00351143950.033
compound eye morphogenesisGO:00017452490.033
Fly
wing disc morphogenesisGO:00074723440.032
axon developmentGO:00615642970.032
immune responseGO:00069552460.031
tissue morphogenesisGO:00487292970.031
regulation of nervous system developmentGO:00519602480.031
post embryonic appendage morphogenesisGO:00351203850.030
negative regulation of biosynthetic processGO:00098902770.030
negative regulation of nucleobase containing compound metabolic processGO:00459342610.030
regulation of phosphate metabolic processGO:00192202100.030
intracellular transportGO:00469072280.030
negative regulation of developmental processGO:00510932010.029
negative regulation of nucleic acid templated transcriptionGO:19035072400.029
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.029
phagocytosisGO:00069092150.029
mating behaviorGO:00076171060.029
Fly
central nervous system developmentGO:00074172010.029
regulation of cell developmentGO:00602842150.029
axon guidanceGO:00074112330.029
protein localizationGO:00081042840.029
embryonic morphogenesisGO:00485982060.029
matingGO:00076181200.029
Fly
open tracheal system developmentGO:00074242040.029
negative regulation of rna metabolic processGO:00512532510.029
reproductive behaviorGO:00190981220.028
Fly
negative regulation of rna biosynthetic processGO:19026792400.028
cell motilityGO:00488702510.028
cilium assemblyGO:0042384380.028
axonogenesisGO:00074092900.028
regulation of transportGO:00510491810.028
tube developmentGO:00352952440.027
neuron projection guidanceGO:00974852410.027
chemotaxisGO:00069352490.027
dorsal ventral pattern formationGO:00099531330.027
regulation of response to stressGO:00801342000.027
detection of chemical stimulus involved in sensory perceptionGO:0050907750.027
appendage developmentGO:00487364010.027
gland developmentGO:00487321910.027
regulation of cellular localizationGO:00603411360.027
synaptic transmissionGO:00072682880.026
deathGO:00162652840.026
programmed cell deathGO:00125012570.026
imaginal disc derived wing morphogenesisGO:00074763370.026
stem cell differentiationGO:00488631170.025
negative regulation of cell communicationGO:00106482230.025
regulation of anatomical structure morphogenesisGO:00226032420.025
camera type eye developmentGO:004301040.025
cellular response to chemical stimulusGO:00708871990.025
response to oxygen containing compoundGO:19017002000.025
negative regulation of multicellular organismal processGO:00512411420.025
defense response to other organismGO:00985422250.025
cell proliferationGO:00082832990.025
homeostatic processGO:00425921990.025
response to lipopolysaccharideGO:003249640.025
tube morphogenesisGO:00352391910.025
cell deathGO:00082192790.025
embryonic development via the syncytial blastodermGO:00017001480.025
response to radiationGO:00093141550.024
spindle organizationGO:00070512530.024
signal transduction by phosphorylationGO:00230141070.024
respiratory system developmentGO:00605412130.024
epithelial cell differentiationGO:00308553220.024
sensory perception of smellGO:0007608800.024
photoreceptor cell differentiationGO:00465301700.024
cellular amino acid metabolic processGO:0006520610.024
negative regulation of signal transductionGO:00099682060.023
regulation of cell cycleGO:00517262910.023
gland morphogenesisGO:00226121450.023
single organism catabolic processGO:00447122280.023
telencephalon developmentGO:002153720.023
regulation of cellular amine metabolic processGO:003323830.023
imaginal disc derived appendage developmentGO:00487373990.023
cell recognitionGO:00080371020.023
eye photoreceptor cell differentiationGO:00017541450.023
columnar cuboidal epithelial cell differentiationGO:00020652560.023
ameboidal type cell migrationGO:00016671510.023
cation transportGO:00068121100.022
carbohydrate derivative metabolic processGO:19011352170.022
salivary gland morphogenesisGO:00074351450.022
growthGO:00400073590.022
regulation of protein metabolic processGO:00512462560.022
compound eye photoreceptor cell differentiationGO:00017511400.022
organic acid metabolic processGO:00060821030.022
salivary gland developmentGO:00074311620.022
blastoderm segmentationGO:00073501590.022
single organism biosynthetic processGO:00447112060.022
body morphogenesisGO:001017120.022
negative regulation of macromolecule biosynthetic processGO:00105582700.022
metal ion transportGO:0030001740.022
g protein coupled receptor signaling pathwayGO:00071861360.022
spermatogenesisGO:00072832000.022
regulation of response to external stimulusGO:00321011150.022
male gamete generationGO:00482322010.022
regulation of phosphorus metabolic processGO:00511742100.022
developmental growthGO:00485892800.021
regulation of developmental growthGO:00486381740.021
regulation of cellular ketone metabolic processGO:001056530.021
wnt signaling pathwayGO:0016055980.021
developmental programmed cell deathGO:00106231380.021
regulation of molecular functionGO:00650092170.021
exocrine system developmentGO:00352721620.021
cellular response to dna damage stimulusGO:00069742230.021
single organism intracellular transportGO:19025822070.020
carboxylic acid metabolic processGO:0019752920.020
segmentationGO:00352822070.020
oxoacid metabolic processGO:00434361030.020
multi organism reproductive behaviorGO:00447051210.020
Fly
response to organophosphorusGO:004668320.020
regulation of cellular amino acid metabolic processGO:000652100.020
positive regulation of intracellular signal transductionGO:19025331160.020
kidney developmentGO:000182230.020
synapse organizationGO:00508081960.020
response to bacteriumGO:00096171980.020
secretionGO:00469031090.020
purine ribonucleotide metabolic processGO:00091501450.019
organelle assemblyGO:00709251980.019
regulation of organelle organizationGO:00330431960.019
hindbrain developmentGO:003090220.019
regulation of mitotic cell cycleGO:00073461900.019
regulation of phosphorylationGO:00423251470.019
organic cyclic compound catabolic processGO:19013611680.019
protein transportGO:00150311550.019
regulation of multi organism processGO:00439001310.019
axis specificationGO:00097981670.019
head developmentGO:00603221350.019
proteolysisGO:00065081920.019
Fly
adult behaviorGO:00305341370.019
regulation of defense responseGO:00313471020.019
organonitrogen compound biosynthetic processGO:19015661170.019
cilium morphogenesisGO:0060271390.019
nucleobase containing small molecule metabolic processGO:00550861740.019
detection of abiotic stimulusGO:0009582660.019
response to woundingGO:0009611940.019
embryonic pattern specificationGO:00098801740.019
retina development in camera type eyeGO:006004140.019
tissue deathGO:00162711020.018
nucleoside phosphate metabolic processGO:00067531620.018
negative regulation of cell differentiationGO:00455961430.018
regulation of mapk cascadeGO:0043408920.018
enzyme linked receptor protein signaling pathwayGO:00071671790.018
nitrogen compound transportGO:0071705850.018
compound eye developmentGO:00487493070.018
Fly
positive regulation of phosphorus metabolic processGO:00105621390.018
endomembrane system organizationGO:00102561190.018
regulation of growthGO:00400082330.018
regulation of cell cycle processGO:00105641810.018
amine metabolic processGO:0009308120.018
adult locomotory behaviorGO:0008344760.018
secretion by cellGO:00329401010.018
regulation of catalytic activityGO:00507901850.018
regulation of synapse structure and activityGO:00508031280.018
mapk cascadeGO:00001651070.018
single organism cellular localizationGO:19025801800.018
cellular component assembly involved in morphogenesisGO:00109271510.018
regulation of immune system processGO:00026821760.018
histolysisGO:00075591020.018
cellular amine metabolic processGO:0044106120.018
protein heterooligomerizationGO:005129140.018
gene silencingGO:00164581380.018
response to nitrogen compoundGO:1901698900.018
regulation of catabolic processGO:00098941700.017
purine nucleotide metabolic processGO:00061631460.017
epithelial cell developmentGO:00020642740.017
negative regulation of signalingGO:00230572190.017
embryo development ending in birth or egg hatchingGO:00097921520.017
regulation of synaptic transmissionGO:0050804690.017
developmental maturationGO:00217001720.017
ras protein signal transductionGO:0007265880.017
regulation of cellular catabolic processGO:00313291570.017
defense response to bacteriumGO:00427421780.017
ribonucleotide metabolic processGO:00092591450.017
regulation of programmed cell deathGO:00430671520.017
chromosome segregationGO:00070591570.017
cellular ketone metabolic processGO:0042180240.017
pigmentationGO:0043473750.017
nucleotide metabolic processGO:00091171610.017
imaginal disc pattern formationGO:0007447910.017
macromolecule catabolic processGO:00090571610.017
regulation of gene expression epigeneticGO:00400291280.017
mitochondrion organizationGO:0007005650.017
purine containing compound metabolic processGO:00725211550.017
mitotic nuclear divisionGO:00070672130.017
meiotic cell cycleGO:00513211710.017
regulation of anatomical structure sizeGO:00900661630.017
chromosome organizationGO:00512763600.017
anterior posterior pattern specificationGO:00099521360.016
protein phosphorylationGO:00064681690.016
ribose phosphate metabolic processGO:00196931450.016
macromolecular complex assemblyGO:00650032560.016
regulation of immune responseGO:00507761180.016
cellular macromolecule localizationGO:00707272200.016
multicellular organismal agingGO:00102591400.016
ovarian follicle cell developmentGO:00307072480.016
multicellular organismal reproductive behaviorGO:00330571100.016
Fly
spinal cord developmentGO:002151010.016
cation transmembrane transportGO:0098655880.016
cellular nitrogen compound catabolic processGO:00442701650.016
regulation of cellular protein metabolic processGO:00322682430.016
positive regulation of developmental processGO:00510941430.016
immune effector processGO:0002252980.016
detection of external stimulusGO:0009581660.016
cell divisionGO:00513012480.016
regulation of neurogenesisGO:00507671580.016
mitotic spindle organizationGO:00070522200.016
dna metabolic processGO:00062592270.016
chemosensory behaviorGO:00076351060.016
establishment or maintenance of cell polarityGO:00071631670.016
chaeta developmentGO:0022416970.015
positive regulation of catalytic activityGO:00430851180.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
organonitrogen compound catabolic processGO:19015651280.015
sensory perception of salty tasteGO:005091430.015
small gtpase mediated signal transductionGO:0007264880.015
regulation of behaviorGO:0050795750.015
muscle structure developmentGO:00610612240.015
aromatic compound catabolic processGO:00194391660.015
monocarboxylic acid transportGO:001571830.015
establishment of protein localizationGO:00451841630.015
innate immune responseGO:00450871440.015
organophosphate metabolic processGO:00196371950.015
apoptotic processGO:00069151590.015
regulation of cell deathGO:00109411730.015
response to endogenous stimulusGO:00097191190.015
positive regulation of phosphate metabolic processGO:00459371390.015
negative regulation of growthGO:0045926840.015
mesenchymal cell differentiationGO:004876210.015
sensory perception of mechanical stimulusGO:0050954720.015
male mating behaviorGO:0060179700.015
biological adhesionGO:00226101380.014
cognitionGO:00508901410.014
salivary gland histolysisGO:0035070880.014
meiotic nuclear divisionGO:00071261510.014
cytoplasmic transportGO:00164821300.014
heterocycle catabolic processGO:00467001660.014
cellular response to organic substanceGO:00713101320.014
behavioral response to painGO:004826630.014
inorganic ion transmembrane transportGO:0098660730.014
cilium organizationGO:0044782410.014
transmembrane transportGO:00550851390.014
determination of adult lifespanGO:00083401370.014
response to alcoholGO:0097305950.014
digestive tract morphogenesisGO:00485461270.014
regulation of cellular component biogenesisGO:00440872010.014
dendrite morphogenesisGO:00488131990.014
wing disc pattern formationGO:0035222660.014
digestive tract developmentGO:00485651490.014
l amino acid importGO:004309220.014
regulation of hydrolase activityGO:0051336970.014
response to organic cyclic compoundGO:0014070890.014
cell projection assemblyGO:0030031940.014
immune response activating signal transductionGO:000275720.014
salt aversionGO:003519930.014
carbohydrate metabolic processGO:0005975820.014
brain developmentGO:00074201200.014
positive regulation of cellular component organizationGO:00511301560.014
cardiovascular system developmentGO:0072358820.014
embryonic axis specificationGO:00005781070.013
cell maturationGO:00484691440.013
dendrite developmentGO:00163582040.013
positive regulation of protein metabolic processGO:00512471280.013
hematopoietic progenitor cell differentiationGO:000224410.013
establishment of tissue polarityGO:0007164870.013
epithelium migrationGO:00901321480.013
anterior posterior axis specificationGO:00099481090.013
wound healingGO:0042060750.013
nucleobase containing compound catabolic processGO:00346551650.013
synaptic target recognitionGO:0008039450.013
meiotic cell cycle processGO:19030461320.013
columnar cuboidal epithelial cell developmentGO:00020662490.013
detection of mechanical stimulus involved in sensory perception of painGO:005096620.013
positive regulation of molecular functionGO:00440931360.013
sensory perception of painGO:001923340.013
regulation of immune effector processGO:0002697520.013
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.013
immune response regulating signaling pathwayGO:000276420.013
wound healing spreading of epidermal cellsGO:003531310.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.013
autophagic cell deathGO:0048102830.013
ribonucleotide catabolic processGO:00092611090.013
negative regulation of cellular component organizationGO:00511291080.013
synapse assemblyGO:00074161430.013
golgi organizationGO:0007030660.013
xenobiotic catabolic processGO:004217810.013
cellular protein localizationGO:00346131600.013
anatomical structure homeostasisGO:0060249970.013
regulation of reproductive processGO:2000241540.013
courtship behaviorGO:0007619680.013
tripartite regional subdivisionGO:00073511030.013
salivary gland cell autophagic cell deathGO:0035071830.013
regulation of apoptotic processGO:00429811300.013
purine nucleoside metabolic processGO:00422781270.013
drinking behaviorGO:004275620.013
mesenchymal cell developmentGO:001403110.013
regulation of response to biotic stimulusGO:0002831630.013
response to organonitrogen compoundGO:0010243750.012
feeding behaviorGO:0007631500.012
stem cell developmentGO:0048864790.012
nucleotide catabolic processGO:00091661090.012
morphogenesis of a polarized epitheliumGO:0001738930.012
regulation of cell morphogenesisGO:00226041630.012
regulation of epithelial cell differentiationGO:003085640.012
connective tissue developmentGO:006144830.012
anterior posterior axis specification embryoGO:00085951030.012
acetate ester metabolic processGO:190061920.012
digestive system developmentGO:00551231490.012
detection of chemical stimulusGO:0009593930.012
regulation of cell proliferationGO:00421271630.012
purine nucleotide catabolic processGO:00061951090.012
tissue migrationGO:00901301550.012
regulation of intracellular transportGO:0032386640.012
positive regulation of hydrolase activityGO:0051345780.012
positive regulation of cell migrationGO:003033520.012
negative regulation of gene expression epigeneticGO:0045814770.012
response to monosaccharideGO:003428440.012
epithelial tube morphogenesisGO:0060562880.012
phenol containing compound metabolic processGO:0018958570.012
camera type eye morphogenesisGO:004859320.012
peptide metabolic processGO:0006518800.012
spermatid differentiationGO:00485151140.012
dorsal closureGO:0007391790.012
positive regulation of phosphorylationGO:0042327870.012
purine ribonucleoside catabolic processGO:00461301120.012
protein complex biogenesisGO:00702712010.012
organelle localizationGO:00516401480.012
peptidyl amino acid modificationGO:00181931050.012
neurotransmitter catabolic processGO:004213510.012
chromatin organizationGO:00063252070.012
negative regulation of mitotic cell cycleGO:00459301090.012
cellular macromolecule catabolic processGO:00442651360.012
l glutamate importGO:005193810.012
positive regulation of programmed cell deathGO:0043068620.012
protein maturationGO:0051604710.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
cell growthGO:00160491080.012
oocyte differentiationGO:00099941450.012
chemical homeostasisGO:0048878920.012
positive regulation of multicellular organismal processGO:00512401430.012
endoderm formationGO:000170630.012
regulation of innate immune responseGO:0045088710.012
negative regulation of nervous system developmentGO:0051961920.012
olfactory behaviorGO:0042048970.012
limb developmentGO:006017310.011
rhythmic processGO:00485111060.011
cellularizationGO:0007349900.011
rna processingGO:00063961470.011
mitotic cell cycle phase transitionGO:00447721380.011
antimicrobial humoral responseGO:0019730990.011
nucleoside catabolic processGO:00091641120.011
nucleoside phosphate catabolic processGO:19012921100.011
oocyte constructionGO:00073081120.011
positive regulation of catabolic processGO:00098961050.011
cell cycle phase transitionGO:00447701400.011
positive regulation of mapk cascadeGO:0043410630.011
regulation of neuron differentiationGO:00456641030.011
ribonucleoside metabolic processGO:00091191270.011
lateral inhibitionGO:00463312060.011
posttranscriptional regulation of gene expressionGO:00106081450.011
regulation of notch signaling pathwayGO:00085931000.011
regulation of protein localizationGO:0032880760.011
male courtship behaviorGO:0008049630.011
organophosphate catabolic processGO:00464341120.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
phosphate ion transportGO:000681740.011
purine containing compound catabolic processGO:00725231120.011
ribonucleoside catabolic processGO:00424541120.011
purine ribonucleotide catabolic processGO:00091541090.011
cellular response to abiotic stimulusGO:0071214580.011
carbohydrate derivative catabolic processGO:19011361180.011
inter male aggressive behaviorGO:0002121600.011
protein processingGO:0016485680.011
positive regulation of cellular component biogenesisGO:0044089800.011
humoral immune responseGO:00069591170.011
synaptic growth at neuromuscular junctionGO:00511241190.011
renal system developmentGO:0072001720.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
cellular response to lipopolysaccharideGO:007122230.011
nucleoside metabolic processGO:00091161270.011
dorsal ventral axis specificationGO:0009950660.011
cation homeostasisGO:0055080510.011
protein modification by small protein conjugation or removalGO:00706471060.011
muscle organ developmentGO:00075171270.011
rna localizationGO:00064031150.011
inorganic cation transmembrane transportGO:0098662610.011
nucleoside triphosphate catabolic processGO:00091431080.011
glycosyl compound catabolic processGO:19016581120.011
dephosphorylationGO:0016311510.011
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.011
regulation of proteolysisGO:0030162870.011
nephron developmentGO:007200630.011
establishment of planar polarityGO:0001736870.011
microtubule based transportGO:0010970420.011
sodium dependent phosphate transportGO:004434120.011
positive regulation of transportGO:0051050920.011
leg disc developmentGO:0035218920.011
regulation of gene silencingGO:0060968630.011
photoreceptor cell developmentGO:0042461960.011
negative regulation of developmental growthGO:0048640640.011
somatic muscle developmentGO:0007525660.011
cell adhesionGO:00071551360.010
regulation of wnt signaling pathwayGO:0030111680.010
regulation of protein modification processGO:00313991120.010
acid secretionGO:004671710.010
regulation of synapse organizationGO:00508071100.010
circulatory system developmentGO:0072359820.010
carbohydrate derivative biosynthetic processGO:1901137850.010
aggressive behaviorGO:0002118630.010
response to hexoseGO:000974630.010
negative regulation of cellular protein metabolic processGO:0032269850.010
nucleoside triphosphate metabolic processGO:00091411200.010
neuropeptide signaling pathwayGO:0007218450.010
ribonucleoside triphosphate catabolic processGO:00092031080.010
notch signaling pathwayGO:00072191200.010

Nep5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.059
nervous system diseaseDOID:86300.021
cardiovascular system diseaseDOID:128700.016
urinary system diseaseDOID:1800.015
disease of metabolismDOID:001466700.013
renal tubular transport diseaseDOID:44700.012
kidney diseaseDOID:55700.012
musculoskeletal system diseaseDOID:1700.011
disease of cellular proliferationDOID:1456600.011
sensory system diseaseDOID:005015500.010