Drosophila melanogaster

15 known processes

Rat1 (Dmel_CG10354)

CG10354 gene product from transcript CG10354-RA

(Aliases: dhp1,RAT1,XRN2,dRAT1,CG10354,Dmel\CG10354)

Rat1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna processingGO:00063961470.776
Worm
mrna metabolic processGO:00160711240.614
cell divisionGO:00513012480.283
rna splicingGO:0008380830.270
mrna processingGO:00063971040.249
regulation of rna splicingGO:0043484690.228
regulation of cell cycleGO:00517262910.224
cell deathGO:00082192790.197
regulation of cell cycle processGO:00105641810.196
nuclear divisionGO:00002803320.178
larval developmentGO:00021641040.174
Worm
spindle organizationGO:00070512530.158
gene silencingGO:00164581380.153
Worm
protein modification processGO:00362114380.153
alternative mrna splicing via spliceosomeGO:0000380600.153
deathGO:00162652840.152
response to organic substanceGO:00100332840.144
rna splicing via transesterification reactionsGO:0000375730.140
embryo development ending in birth or egg hatchingGO:00097921520.116
Worm
organelle assemblyGO:00709251980.108
positive regulation of developmental growthGO:0048639620.107
posttranscriptional gene silencingGO:0016441460.097
Worm
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.096
regulation of cell divisionGO:0051302720.096
cellular response to chemical stimulusGO:00708871990.092
regulation of cell deathGO:00109411730.092
negative regulation of cell cycle processGO:00109481090.092
regulation of mrna processingGO:0050684710.091
organelle fissionGO:00482853400.090
regulation of mrna splicing via spliceosomeGO:0048024640.090
regulation of alternative mrna splicing via spliceosomeGO:0000381600.090
body morphogenesisGO:001017120.087
mitotic spindle elongationGO:0000022810.085
cytokinesisGO:0000910900.084
cell proliferationGO:00082832990.075
positive regulation of nucleobase containing compound metabolic processGO:00459353320.075
macromolecule catabolic processGO:00090571610.074
Worm
positive regulation of transcription dna templatedGO:00458932660.074
regulation of cell cycle phase transitionGO:19019871300.073
vesicle mediated transportGO:00161923810.072
regulation of programmed cell deathGO:00430671520.070
growthGO:00400073590.070
regulation of mrna metabolic processGO:1903311720.069
positive regulation of macromolecule metabolic processGO:00106044050.068
negative regulation of gene expressionGO:00106293870.068
Worm
meiotic cell cycleGO:00513211710.067
regulation of mitotic cell cycleGO:00073461900.067
negative regulation of mitotic cell cycleGO:00459301090.065
mrna splicing via spliceosomeGO:0000398730.065
anatomical structure homeostasisGO:0060249970.065
regulation of gene expression epigeneticGO:00400291280.062
Worm
programmed cell deathGO:00125012570.062
meiotic nuclear divisionGO:00071261510.061
organophosphate metabolic processGO:00196371950.059
negative regulation of signalingGO:00230572190.058
dna metabolic processGO:00062592270.058
catabolic processGO:00090564090.055
Worm
negative regulation of response to stimulusGO:00485852580.052
axon developmentGO:00615642970.051
intracellular signal transductionGO:00355563000.050
nucleobase containing compound catabolic processGO:00346551650.050
Worm
purine ribonucleoside metabolic processGO:00461281270.050
response to abiotic stimulusGO:00096283410.050
cellular catabolic processGO:00442483720.049
Worm
cellular response to nitrogen compoundGO:1901699510.049
organic cyclic compound catabolic processGO:19013611680.048
Worm
cell cycle phase transitionGO:00447701400.048
single organism biosynthetic processGO:00447112060.048
agingGO:00075681430.048
gonad developmentGO:0008406500.046
regulation of meiosisGO:004002030.045
small molecule metabolic processGO:00442813050.043
protein complex assemblyGO:00064612000.043
organonitrogen compound metabolic processGO:19015643180.043
organic substance catabolic processGO:19015753080.043
Worm
establishment of localization in cellGO:00516494020.043
cellular response to organic substanceGO:00713101320.042
multi multicellular organism processGO:00447061230.041
mitotic dna integrity checkpointGO:0044774750.041
protein catabolic processGO:00301631010.040
positive regulation of growthGO:0045927750.040
regulation of mrna 3 end processingGO:003144070.039
cellular macromolecular complex assemblyGO:00346221530.038
regulation of mitotic cell cycle phase transitionGO:19019901300.038
gene silencing by mirnaGO:0035195220.038
Worm
endocytosisGO:00068973100.036
mitotic g2 m transition checkpointGO:0044818700.036
nucleoside triphosphate catabolic processGO:00091431080.036
g2 dna damage checkpointGO:0031572690.036
positive regulation of signal transductionGO:00099672230.035
regulation of dna metabolic processGO:0051052340.035
protein phosphorylationGO:00064681690.035
rna interferenceGO:0016246270.034
regulation of apoptotic processGO:00429811300.034
regulation of catalytic activityGO:00507901850.034
posttranscriptional regulation of gene expressionGO:00106081450.034
Worm
cell cycle checkpointGO:0000075950.034
nucleotide catabolic processGO:00091661090.034
reproductive system developmentGO:0061458740.034
axonogenesisGO:00074092900.034
apoptotic processGO:00069151590.033
positive regulation of multicellular organismal processGO:00512401430.033
negative regulation of cell communicationGO:00106482230.032
negative regulation of developmental processGO:00510932010.032
carbohydrate derivative metabolic processGO:19011352170.031
protein complex biogenesisGO:00702712010.031
nucleoside metabolic processGO:00091161270.031
development of primary sexual characteristicsGO:0045137500.031
response to nitrogen compoundGO:1901698900.030
maintenance of locationGO:0051235730.030
reproductive structure developmentGO:0048608740.030
cellular protein localizationGO:00346131600.029
negative regulation of mitotic cell cycle phase transitionGO:19019911030.029
dna integrity checkpointGO:0031570810.029
cell motilityGO:00488702510.029
regulation of developmental growthGO:00486381740.029
transcription from rna polymerase ii promoterGO:00063663680.028
response to endogenous stimulusGO:00097191190.028
multi organism reproductive behaviorGO:00447051210.028
wnt signaling pathwayGO:0016055980.028
positive regulation of gene expressionGO:00106282900.028
positive regulation of cellular component organizationGO:00511301560.028
cellular macromolecule catabolic processGO:00442651360.028
Worm
oxoacid metabolic processGO:00434361030.027
ribonucleotide metabolic processGO:00092591450.027
cellular protein modification processGO:00064644380.027
cellular macromolecule localizationGO:00707272200.027
cellular response to dna damage stimulusGO:00069742230.027
dna damage checkpointGO:0000077780.027
dna replicationGO:0006260480.027
purine ribonucleoside triphosphate catabolic processGO:00092071080.027
spindle elongationGO:0051231830.027
regulation of anatomical structure morphogenesisGO:00226032420.027
axon guidanceGO:00074112330.027
purine ribonucleotide catabolic processGO:00091541090.026
purine nucleoside triphosphate metabolic processGO:00091441190.026
single organism intracellular transportGO:19025822070.026
posttranscriptional gene silencing by rnaGO:0035194450.026
Worm
regulation of phosphorus metabolic processGO:00511742100.025
positive regulation of rna metabolic processGO:00512542710.025
negative regulation of signal transductionGO:00099682060.024
nucleoside phosphate metabolic processGO:00067531620.024
localization of cellGO:00516742570.024
sex differentiationGO:0007548810.024
regulation of protein complex assemblyGO:0043254420.024
positive regulation of nitrogen compound metabolic processGO:00511733540.023
regulation of organelle organizationGO:00330431960.023
camera type eye developmentGO:004301040.023
aromatic compound catabolic processGO:00194391660.022
Worm
single organism nuclear importGO:1902593510.022
regionalizationGO:00030024160.022
negative regulation of biosynthetic processGO:00098902770.022
negative regulation of macromolecule biosynthetic processGO:00105582700.022
protein localization to organelleGO:0033365820.022
nucleotide excision repairGO:000628980.021
positive regulation of response to stimulusGO:00485843230.021
nucleoside phosphate catabolic processGO:19012921100.021
purine containing compound metabolic processGO:00725211550.021
ribonucleoprotein complex subunit organizationGO:0071826280.021
carboxylic acid metabolic processGO:0019752920.021
heterocycle catabolic processGO:00467001660.021
Worm
negative regulation of cell deathGO:0060548810.021
mitotic cell cycle checkpointGO:0007093880.021
multicellular organismal reproductive behaviorGO:00330571100.021
negative regulation of rna metabolic processGO:00512532510.021
intracellular transportGO:00469072280.020
ribonucleoside catabolic processGO:00424541120.020
protein ubiquitinationGO:0016567700.020
cell migrationGO:00164772380.020
nucleoside catabolic processGO:00091641120.020
regulation of transportGO:00510491810.020
protein transportGO:00150311550.020
ribonucleoside metabolic processGO:00091191270.020
glycosyl compound metabolic processGO:19016571270.020
phagocytosisGO:00069092150.019
negative regulation of cell cycle phase transitionGO:19019881030.019
nucleoside triphosphate metabolic processGO:00091411200.019
regulation of phosphorylationGO:00423251470.019
regulation of cellular component sizeGO:0032535980.018
regulation of multicellular organismal developmentGO:20000264140.018
Worm
stem cell differentiationGO:00488631170.018
positive regulation of cellular biosynthetic processGO:00313283160.018
sensory organ morphogenesisGO:00905962600.018
cytoplasmic transportGO:00164821300.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
purine nucleoside metabolic processGO:00422781270.018
hematopoietic or lymphoid organ developmentGO:0048534570.017
mitotic dna damage checkpointGO:0044773740.017
single organism catabolic processGO:00447122280.017
rna 3 end processingGO:0031123450.017
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
regulation of cell proliferationGO:00421271630.017
multi organism behaviorGO:00517051750.017
ras protein signal transductionGO:0007265880.016
negative regulation of cellular metabolic processGO:00313243820.016
mitotic cell cycle phase transitionGO:00447721380.016
purine nucleotide metabolic processGO:00061631460.016
positive regulation of signalingGO:00230562430.016
establishment of organelle localizationGO:00516561220.016
cellular nitrogen compound catabolic processGO:00442701650.016
Worm
cellular protein complex assemblyGO:0043623710.016
reproductive behaviorGO:00190981220.016
positive regulation of cell communicationGO:00106472500.016
purine nucleoside monophosphate metabolic processGO:0009126500.016
protein modification by small protein conjugationGO:0032446790.016
establishment of protein localizationGO:00451841630.016
negative regulation of cell cycleGO:00457861160.016
purine nucleoside catabolic processGO:00061521120.016
regulation of localizationGO:00328792750.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.015
positive regulation of macromolecule biosynthetic processGO:00105572830.015
protein importGO:0017038550.015
protein modification by small protein conjugation or removalGO:00706471060.015
regulation of nuclear divisionGO:0051783580.015
genitalia developmentGO:0048806260.015
positive regulation of epidermal growth factor activated receptor activityGO:004574110.015
regulation of wnt signaling pathwayGO:0030111680.015
response to oxygen containing compoundGO:19017002000.015
homeostatic processGO:00425921990.015
guanosine containing compound catabolic processGO:1901069740.015
purine ribonucleotide metabolic processGO:00091501450.014
regulation of protein metabolic processGO:00512462560.014
glycosyl compound catabolic processGO:19016581120.014
regulation of cellular component biogenesisGO:00440872010.014
positive regulation of rna biosynthetic processGO:19026802660.014
response to oxidative stressGO:0006979860.014
positive regulation of cellular component biogenesisGO:0044089800.014
cellular homeostasisGO:0019725800.014
interspecies interaction between organismsGO:0044419160.014
response to organic cyclic compoundGO:0014070890.014
ribose phosphate metabolic processGO:00196931450.014
gene silencing by rnaGO:0031047570.014
Worm
regulation of cellular protein metabolic processGO:00322682430.014
multicellular organismal agingGO:00102591400.014
ribosomal large subunit biogenesisGO:004227310.014
stem cell maintenanceGO:0019827670.013
small gtpase mediated signal transductionGO:0007264880.013
taxisGO:00423303040.013
purine ribonucleoside catabolic processGO:00461301120.013
mitotic spindle organizationGO:00070522200.013
organic acid metabolic processGO:00060821030.013
purine nucleoside triphosphate catabolic processGO:00091461080.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.013
ubiquitin dependent protein catabolic processGO:0006511780.013
morphogenesis of follicular epitheliumGO:0016333360.013
retina development in camera type eyeGO:006004140.012
cellular amine metabolic processGO:0044106120.012
organic substance transportGO:00717022570.012
organophosphate catabolic processGO:00464341120.012
positive regulation of multicellular organism growthGO:0040018210.012
cellular amino acid metabolic processGO:0006520610.012
regulation of multicellular organism growthGO:0040014400.012
purine nucleotide catabolic processGO:00061951090.012
determination of adult lifespanGO:00083401370.011
negative regulation of intracellular signal transductionGO:1902532570.011
negative regulation of neurotransmitter secretionGO:004692920.011
mitotic g2 dna damage checkpointGO:0007095690.011
mrna 3 end processingGO:0031124280.011
tricarboxylic acid metabolic processGO:007235010.011
kidney morphogenesisGO:006099330.011
organelle localizationGO:00516401480.010
purine ribonucleoside monophosphate metabolic processGO:0009167500.010
dendrite developmentGO:00163582040.010
response to dsrnaGO:0043331150.010
negative regulation of programmed cell deathGO:0043069720.010
purine ribonucleoside triphosphate metabolic processGO:00092051190.010
cell cell signaling involved in cell fate commitmentGO:00451682100.010
axis specificationGO:00097981670.010

Rat1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
osteogenesis imperfectaDOID:1234700.018
musculoskeletal system diseaseDOID:1700.018
bone development diseaseDOID:008000600.018
osteochondrodysplasiaDOID:225600.018
bone diseaseDOID:008000100.018
connective tissue diseaseDOID:6500.018