Drosophila melanogaster

163 known processes

Apc2 (Dmel_CG6193)

Adenomatous polyposis coli tumor suppressor homolog 2

(Aliases: d-APC2,Dmel\CG6193,dAPC2,E-APC,CG6193,E-APC dAPC2,apc2,dAPC2/E-APC,D-APC2,APC2,APC,dApc2)

Apc2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment or maintenance of cell polarityGO:00071631670.732
regionalizationGO:00030024160.628
transcription from rna polymerase ii promoterGO:00063663680.584
Worm
epithelial cell differentiationGO:00308553220.557
Mouse
epithelial cell developmentGO:00020642740.555
blastoderm segmentationGO:00073501590.532
neurological system processGO:00508773580.517
embryonic pattern specificationGO:00098801740.473
axis specificationGO:00097981670.468
Mouse
actin cytoskeleton organizationGO:00300362060.432
oocyte axis specificationGO:00073091080.364
wing disc morphogenesisGO:00074723440.352
wnt signaling pathwayGO:0016055980.316
regulation of cell differentiationGO:00455953020.295
Mouse Fly
anterior posterior pattern specificationGO:00099521360.293
Mouse
imaginal disc derived appendage morphogenesisGO:00351143950.282
negative regulation of gene expressionGO:00106293870.281
Human
purine nucleoside triphosphate metabolic processGO:00091441190.258
morphogenesis of an epitheliumGO:00020092760.256
localization of cellGO:00516742570.240
negative regulation of rna metabolic processGO:00512532510.231
post embryonic appendage morphogenesisGO:00351203850.225
digestive system developmentGO:00551231490.211
Worm
positive regulation of biosynthetic processGO:00098913160.207
Worm
single organism cellular localizationGO:19025801800.206
Human
anterior posterior axis specificationGO:00099481090.202
regulation of immune system processGO:00026821760.199
Mouse
appendage morphogenesisGO:00351073970.187
tissue morphogenesisGO:00487292970.185
cuticle developmentGO:0042335860.184
glycosyl compound catabolic processGO:19016581120.183
regulation of embryonic developmentGO:0045995680.183
Worm
eye morphogenesisGO:00485922600.182
Fly
protein localizationGO:00081042840.181
Human Mouse Worm Fly
cell maturationGO:00484691440.180
positive regulation of response to stimulusGO:00485843230.171
Worm
appendage developmentGO:00487364010.169
negative regulation of developmental processGO:00510932010.165
Mouse Worm Fly
ovarian follicle cell developmentGO:00307072480.163
regulation of cellular amino acid metabolic processGO:000652100.161
Rat
regulation of pole plasm oskar mrna localizationGO:0007317270.156
actin filament organizationGO:00070151260.156
oocyte anterior posterior axis specificationGO:0007314720.156
regulation of cell developmentGO:00602842150.152
Fly
segmentationGO:00352822070.148
embryo development ending in birth or egg hatchingGO:00097921520.147
negative regulation of nucleobase containing compound metabolic processGO:00459342610.147
embryonic axis specificationGO:00005781070.146
digestive tract morphogenesisGO:00485461270.145
Worm
imaginal disc derived appendage developmentGO:00487373990.144
negative regulation of signalingGO:00230572190.144
cell motilityGO:00488702510.142
Human Mouse Worm
oocyte constructionGO:00073081120.140
maternal determination of anterior posterior axis embryoGO:0008358740.138
imaginal disc derived wing morphogenesisGO:00074763370.138
regulation of anatomical structure morphogenesisGO:00226032420.137
Mouse Worm Fly
regulation of organelle organizationGO:00330431960.135
Human Mouse
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.135
regulation of mitotic cell cycleGO:00073461900.134
Human Mouse
regulation of multicellular organismal developmentGO:20000264140.134
Mouse Worm Fly
cuticle pattern formationGO:0035017270.133
immune system processGO:00023763470.127
Mouse
embryonic morphogenesisGO:00485982060.126
establishment of planar polarityGO:0001736870.121
digestive tract developmentGO:00485651490.120
Worm
small molecule metabolic processGO:00442813050.118
Rat
regulation of cellular component biogenesisGO:00440872010.115
Human Mouse Fly
anterior posterior axis specification embryoGO:00085951030.115
positive regulation of nitrogen compound metabolic processGO:00511733540.113
Worm
establishment or maintenance of cytoskeleton polarityGO:0030952440.111
regulation of developmental growthGO:00486381740.105
positive regulation of signal transductionGO:00099672230.105
Worm
protein modification processGO:00362114380.101
Human
cellular protein localizationGO:00346131600.100
Human Mouse Worm Fly
organelle localizationGO:00516401480.099
purine ribonucleotide catabolic processGO:00091541090.097
cell proliferationGO:00082832990.097
tube morphogenesisGO:00352391910.097
Worm
tube developmentGO:00352952440.095
Worm
growthGO:00400073590.094
gastrulation involving germ band extensionGO:0010004360.094
germarium derived egg chamber formationGO:00072931010.091
negative regulation of transcription dna templatedGO:00458922370.090
regulation of embryonic cell shapeGO:0016476300.090
Worm
regulation of cell cycle phase transitionGO:19019871300.089
Human
regulation of transportGO:00510491810.088
Human
negative regulation of response to stimulusGO:00485852580.088
negative regulation of signal transductionGO:00099682060.088
gastrulationGO:0007369700.087
Worm
compound eye developmentGO:00487493070.086
Fly
respiratory system developmentGO:00605412130.085
ribonucleotide metabolic processGO:00092591450.085
epidermal growth factor receptor signaling pathwayGO:0007173580.085
mitotic spindle organizationGO:00070522200.084
Worm
regulation of cell adhesionGO:0030155270.084
Mouse
regulation of response to stressGO:00801342000.083
negative regulation of cellular metabolic processGO:00313243820.080
Human Mouse
regulation of cell morphogenesisGO:00226041630.080
Worm
carbohydrate derivative metabolic processGO:19011352170.078
phosphorylationGO:00163102940.077
Human Mouse
columnar cuboidal epithelial cell developmentGO:00020662490.077
developmental growthGO:00485892800.076
establishment of tissue polarityGO:0007164870.076
positive regulation of transportGO:0051050920.076
oocyte differentiationGO:00099941450.076
negative regulation of cellular biosynthetic processGO:00313272770.076
positive regulation of cellular component organizationGO:00511301560.075
Human Mouse Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.074
single organism intracellular transportGO:19025822070.074
Human Worm
negative regulation of multicellular organismal processGO:00512411420.073
Mouse Worm Fly
organonitrogen compound metabolic processGO:19015643180.072
Rat
cell deathGO:00082192790.071
Human Mouse Fly
regulation of cellular amine metabolic processGO:003323830.071
Rat
oocyte developmentGO:00485991240.070
negative regulation of nucleic acid templated transcriptionGO:19035072400.070
positive regulation of macromolecule metabolic processGO:00106044050.068
regulation of cellular protein metabolic processGO:00322682430.067
Human
negative regulation of rna biosynthetic processGO:19026792400.066
positive regulation of intracellular signal transductionGO:19025331160.066
axonogenesisGO:00074092900.065
axon developmentGO:00615642970.065
positive regulation of cellular amine metabolic processGO:003324000.064
regulation of programmed cell deathGO:00430671520.064
Human Mouse Fly
response to biotic stimulusGO:00096072940.063
instar larval developmentGO:0002168550.063
imaginal disc derived wing vein morphogenesisGO:0008586440.063
regulation of cell cycleGO:00517262910.063
Human Mouse
regulation of epithelial cell proliferationGO:005067840.062
Mouse
cytoplasm organizationGO:0007028640.062
tripartite regional subdivisionGO:00073511030.061
enzyme linked receptor protein signaling pathwayGO:00071671790.061
negative regulation of nitrogen compound metabolic processGO:00511722650.059
dorsal appendage formationGO:0046843470.058
biological adhesionGO:00226101380.058
negative regulation of cell communicationGO:00106482230.058
regulation of transcription from rna polymerase ii promoterGO:00063573780.057
Worm
regulation of cellular localizationGO:00603411360.057
Human Mouse
carbohydrate derivative catabolic processGO:19011361180.056
regulation of reproductive processGO:2000241540.056
Mouse
establishment of localization in cellGO:00516494020.055
vesicle mediated transportGO:00161923810.055
Worm
proteolysisGO:00065081920.055
Human Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.054
regulation of nervous system developmentGO:00519602480.054
response to radiationGO:00093141550.054
purine ribonucleoside triphosphate catabolic processGO:00092071080.053
morphogenesis of embryonic epitheliumGO:0016331940.052
response to ionizing radiationGO:0010212320.052
cellular ketone metabolic processGO:0042180240.052
Rat
single organism behaviorGO:00447083910.052
gastrulation with mouth forming firstGO:0001703360.051
regulation of mapk cascadeGO:0043408920.051
Mouse
immune responseGO:00069552460.051
response to external biotic stimulusGO:00432072930.051
dorsal closureGO:0007391790.050
cell divisionGO:00513012480.050
Human Mouse Worm
positive regulation of cell communicationGO:00106472500.050
Worm
nucleotide catabolic processGO:00091661090.049
purine nucleotide catabolic processGO:00061951090.049
regulation of cell deathGO:00109411730.049
Human Mouse Fly
regulation of molecular functionGO:00650092170.049
Human
stem cell proliferationGO:0072089880.048
pole plasm mrna localizationGO:0019094490.048
response to abiotic stimulusGO:00096283410.047
ribonucleoside metabolic processGO:00091191270.047
heterocycle catabolic processGO:00467001660.046
hindbrain developmentGO:003090220.046
actin filament based processGO:00300292200.046
compound eye morphogenesisGO:00017452490.046
Fly
positive regulation of molecular functionGO:00440931360.046
periodic partitioningGO:0007365290.045
defense response to other organismGO:00985422250.044
regulation of intracellular signal transductionGO:19025312360.044
Mouse
dorsal ventral pattern formationGO:00099531330.044
Mouse
organelle fissionGO:00482853400.043
Human Mouse
positive regulation of cell proliferationGO:0008284470.042
deathGO:00162652840.042
Human Mouse Fly
pole plasm assemblyGO:0007315610.042
stem cell developmentGO:0048864790.042
Mouse
cell cycle phase transitionGO:00447701400.042
Human Mouse
cognitionGO:00508901410.041
response to organic substanceGO:00100332840.041
Rat
regulation of hydrolase activityGO:0051336970.041
nucleoside phosphate catabolic processGO:19012921100.041
protein polymerizationGO:0051258420.041
Mouse
actin filament bundle organizationGO:0061572280.040
reproductive structure developmentGO:0048608740.040
Mouse
mitotic cytokinesisGO:0000281500.039
Human Mouse
intracellular signal transductionGO:00355563000.039
Mouse
regulation of organ morphogenesisGO:2000027780.039
Mouse Fly
regulation of growthGO:00400082330.038
negative regulation of wnt signaling pathwayGO:0030178280.038
regulation of phosphorylationGO:00423251470.038
Human Mouse
cell migrationGO:00164772380.037
Human Mouse Worm
cellular protein modification processGO:00064644380.037
Human
positive regulation of organelle organizationGO:0010638650.037
Mouse
response to other organismGO:00517072930.037
positive regulation of catabolic processGO:00098961050.037
negative regulation of biosynthetic processGO:00098902770.036
nuclear importGO:0051170510.035
Human
cellular response to oxygen containing compoundGO:1901701790.035
imaginal disc derived female genitalia developmentGO:000748660.035
regulation of mitotic cell cycle phase transitionGO:19019901300.035
Human
regulation of cell cycle processGO:00105641810.035
Human Mouse
organonitrogen compound catabolic processGO:19015651280.035
ribonucleoside triphosphate catabolic processGO:00092031080.035
positive regulation of protein metabolic processGO:00512471280.035
apoptotic processGO:00069151590.034
Human Mouse
regulation of phosphate metabolic processGO:00192202100.034
Human Mouse
cellular protein complex assemblyGO:0043623710.034
Mouse
establishment of cell polarityGO:0030010400.034
positive regulation of cellular biosynthetic processGO:00313283160.034
Worm
protein import into nucleusGO:0006606510.033
Human
intracellular protein transportGO:00068861040.033
Human Worm Fly
negative regulation of protein modification processGO:0031400290.033
Human
cell surface receptor signaling pathway involved in heart developmentGO:006131130.033
camera type eye developmentGO:004301040.032
Mouse
protein maturationGO:0051604710.032
Human
positive regulation of developmental processGO:00510941430.032
Mouse
asymmetric cell divisionGO:0008356370.032
Worm
malpighian tubule developmentGO:0072002640.032
mesoderm developmentGO:0007498780.032
defense response to bacteriumGO:00427421780.031
pole plasm rna localizationGO:0007316520.031
regulation of multi organism processGO:00439001310.031
body morphogenesisGO:001017120.031
Worm
regulation of protein serine threonine kinase activityGO:0071900250.031
Human
regulation of oocyte developmentGO:0060281270.031
organic substance catabolic processGO:19015753080.031
eggshell chorion assemblyGO:0007306660.031
regulation of protein metabolic processGO:00512462560.030
purine containing compound catabolic processGO:00725231120.029
catabolic processGO:00090564090.029
purine ribonucleoside metabolic processGO:00461281270.029
endocytosisGO:00068973100.029
Worm
cellularizationGO:0007349900.029
stem cell maintenanceGO:0019827670.029
Mouse
positive regulation of nucleocytoplasmic transportGO:0046824240.029
single organismal cell cell adhesionGO:0016337450.029
positive regulation of phosphorus metabolic processGO:00105621390.028
gene silencingGO:00164581380.028
regulation of phosphorus metabolic processGO:00511742100.028
Human Mouse
organic cyclic compound catabolic processGO:19013611680.028
nucleotide metabolic processGO:00091171610.028
protein phosphorylationGO:00064681690.028
Human
positive regulation of signalingGO:00230562430.027
Worm
cellular response to chemical stimulusGO:00708871990.027
Rat
eggshell formationGO:00307031050.027
organic substance transportGO:00717022570.027
Human Worm Fly
positive regulation of phosphorylationGO:0042327870.027
positive regulation of immune system processGO:0002684680.027
positive regulation of immune responseGO:0050778630.027
chromosome segregationGO:00070591570.027
Human Mouse
ribonucleoside triphosphate metabolic processGO:00091991190.027
ribonucleotide catabolic processGO:00092611090.027
regulation of wnt signaling pathwayGO:0030111680.026
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.026
learning or memoryGO:00076111410.026
regulation of bmp signaling pathwayGO:0030510230.026
regulation of intracellular protein transportGO:0033157460.026
Human
positive regulation of i kappab kinase nf kappab signalingGO:004312310.026
establishment of organelle localizationGO:00516561220.025
regulation of cell shapeGO:00083601130.025
Worm
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.025
mitotic nuclear divisionGO:00070672130.025
Human Mouse
single organism catabolic processGO:00447122280.025
Human Mouse
phenol containing compound metabolic processGO:0018958570.025
positive regulation of cellular protein metabolic processGO:00322701180.025
mitotic cell cycle phase transitionGO:00447721380.025
Human Mouse
positive regulation of multi organism processGO:0043902400.025
nucleoside phosphate metabolic processGO:00067531620.025
nucleoside triphosphate metabolic processGO:00091411200.025
purine ribonucleoside catabolic processGO:00461301120.025
regulation of innate immune responseGO:0045088710.025
taxisGO:00423303040.024
positive regulation of rna biosynthetic processGO:19026802660.024
Worm
nucleoside catabolic processGO:00091641120.024
cell fate specificationGO:0001708710.024
Worm
cellular nitrogen compound catabolic processGO:00442701650.024
bmp signaling pathwayGO:0030509270.024
aromatic compound catabolic processGO:00194391660.024
dna metabolic processGO:00062592270.024
programmed cell deathGO:00125012570.024
Human Mouse Fly
regulation of nucleocytoplasmic transportGO:0046822350.024
Human
oxoacid metabolic processGO:00434361030.023
Rat
head developmentGO:00603221350.023
sensory organ morphogenesisGO:00905962600.023
Fly
regulation of protein modification processGO:00313991120.023
Human
regulation of embryonic pattern specificationGO:1902875270.023
positive regulation of catalytic activityGO:00430851180.023
dorsal ventral axis specificationGO:0009950660.023
reproductive system developmentGO:0061458740.023
Mouse
epidermis developmentGO:0008544650.023
Mouse
protein targetingGO:0006605640.023
Human
positive regulation of protein modification processGO:0031401580.023
protein localization to nucleusGO:0034504550.023
Human
mapk cascadeGO:00001651070.023
Mouse
head involutionGO:0008258350.023
cellular catabolic processGO:00442483720.023
Human Mouse
nucleobase containing small molecule metabolic processGO:00550861740.023
negative regulation of molecular functionGO:0044092510.023
Human
purine ribonucleotide metabolic processGO:00091501450.023
regulation of localizationGO:00328792750.022
Human Mouse Worm
response to bacteriumGO:00096171980.022
renal system developmentGO:0072001720.022
Mouse
spindle organizationGO:00070512530.022
Worm
ribonucleoside catabolic processGO:00424541120.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.022
purine containing compound metabolic processGO:00725211550.022
regulation of defense response to bacteriumGO:1900424300.022
defense response to fungusGO:0050832480.022
negative regulation of cell cell adhesionGO:002240880.022
regulation of toll signaling pathwayGO:0008592170.022
cytokinesisGO:0000910900.021
Human Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
Worm
negative regulation of cell cycle processGO:00109481090.021
Human
non canonical wnt signaling pathwayGO:003556780.021
regulation of cellular ketone metabolic processGO:001056530.021
Rat
purine nucleoside catabolic processGO:00061521120.021
positive regulation of cell cycleGO:0045787430.021
actin filament bundle assemblyGO:0051017260.021
secondary metabolic processGO:0019748750.021
morphogenesis of a polarized epitheliumGO:0001738930.020
protein complex assemblyGO:00064612000.020
Human Mouse Fly
positive regulation of jun kinase activityGO:004350740.020
immune response regulating signaling pathwayGO:000276420.020
ventral furrow formationGO:0007370170.020
carboxylic acid metabolic processGO:0019752920.020
Rat
antimicrobial peptide biosynthetic processGO:0002777380.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.020
positive regulation of protein phosphorylationGO:0001934340.020
cell substrate adhesionGO:0031589100.020
defense response to gram negative bacteriumGO:0050829940.020
nuclear transportGO:0051169720.020
Human Worm
development of primary sexual characteristicsGO:0045137500.020
secretion by cellGO:00329401010.020
anatomical structure homeostasisGO:0060249970.020
Mouse
ameboidal type cell migrationGO:00016671510.019
camera type eye morphogenesisGO:004859320.019
organophosphate catabolic processGO:00464341120.019
single organism nuclear importGO:1902593510.019
Human
regulation of phosphatase activityGO:001092130.019
regulation of transpositionGO:0010528130.019
negative regulation of cell cycleGO:00457861160.019
Human
response to light stimulusGO:00094161240.019
developmental maturationGO:00217001720.019
developmental pigmentationGO:0048066680.019
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.019
glycosyl compound metabolic processGO:19016571270.019
regulation of notch signaling pathwayGO:00085931000.019
regulation of catalytic activityGO:00507901850.019
Human
positive regulation of protein transportGO:0051222370.019
positive regulation of mapk cascadeGO:0043410630.018
positive regulation of gene expressionGO:00106282900.018
Worm
regulation of catabolic processGO:00098941700.018
regulation of cell maturationGO:1903429270.018
oocyte microtubule cytoskeleton organizationGO:0016325350.018
nuclear divisionGO:00002803320.018
Human Mouse
negative regulation of cell deathGO:0060548810.018
Mouse Fly
sensory perceptionGO:00076001960.018
long term memoryGO:0007616620.018
muscle organ developmentGO:00075171270.018
purine nucleotide metabolic processGO:00061631460.018
chorion containing eggshell formationGO:00073041050.018
toll signaling pathwayGO:0008063250.018
protein transportGO:00150311550.017
Human Worm Fly
somatic stem cell divisionGO:0048103370.017
protein importGO:0017038550.017
Human
intracellular mrna localizationGO:0008298660.017
meiotic nuclear divisionGO:00071261510.017
cytoskeleton dependent cytokinesisGO:0061640810.017
Human Mouse
cell adhesionGO:00071551360.017
regulation of cellular response to oxidative stressGO:190040740.017
regulation of intracellular transportGO:0032386640.017
Human
canonical wnt signaling pathwayGO:0060070210.017
Human Mouse
positive regulation of melanization defense responseGO:003500810.017
open tracheal system developmentGO:00074242040.017
regulation of response to external stimulusGO:00321011150.017
epithelial cell migrationGO:00106311480.017
establishment or maintenance of bipolar cell polarityGO:0061245340.016
positive regulation of intracellular transportGO:0032388420.016
response to growth factorGO:0070848310.016
Rat
innate immune responseGO:00450871440.016
molting cycle chitin based cuticleGO:0007591560.016
negative regulation of cell differentiationGO:00455961430.016
Mouse Fly
regulation of cell junction assemblyGO:190188820.016
segment polarity determinationGO:0007367250.016
purine nucleoside metabolic processGO:00422781270.016
nucleus localizationGO:0051647340.016
protein targeting to nucleusGO:0044744510.016
Human
mesenchymal cell differentiationGO:004876210.016
endodermal cell fate commitmentGO:000171130.016
Worm
nucleoside metabolic processGO:00091161270.016
regulation of cell divisionGO:0051302720.016
Human Mouse
positive regulation of phosphate metabolic processGO:00459371390.016
peptidyl threonine modificationGO:001821030.016
molting cycleGO:0042303560.015
positive regulation of stem cell differentiationGO:200073830.015
regulation of response to biotic stimulusGO:0002831630.015
regulation of immune responseGO:00507761180.015
positive regulation of cell cycle processGO:0090068280.015
negative regulation of cellular component organizationGO:00511291080.015
Human Mouse
regulation of gene expression epigeneticGO:00400291280.015
kidney developmentGO:000182230.015
Mouse
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.014
regulation of compound eye pigmentationGO:004807670.014
cell cycle arrestGO:000705040.014
Human
regulation of actin filament based processGO:0032970420.014
actin mediated cell contractionGO:0070252210.014
negative regulation of nervous system developmentGO:0051961920.014
chitin based embryonic cuticle biosynthetic processGO:0008362160.014
meiosis iGO:0007127590.014
regulation of cell cell adhesionGO:0022407210.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
Worm
response to organic cyclic compoundGO:0014070890.014
fertilizationGO:0009566260.014
regulation of jnk cascadeGO:0046328400.014
positive regulation of macromolecule biosynthetic processGO:00105572830.014
Worm
positive regulation of antimicrobial peptide productionGO:0002225280.014
regulation of cell proliferationGO:00421271630.014
Human Mouse
regulation of cell motilityGO:2000145230.014
Human Mouse Worm
response to oxygen containing compoundGO:19017002000.014
Rat
macromolecular complex assemblyGO:00650032560.014
Human Mouse Fly
regulation of cellular component movementGO:0051270420.014
Human Mouse Worm
positive regulation of mitotic cell cycleGO:0045931340.014
cell junction assemblyGO:0034329420.014
ras protein signal transductionGO:0007265880.014
regulation of secretionGO:0051046440.014
positive regulation of secretionGO:0051047220.014
stem cell divisionGO:0017145690.014
regulation of organ growthGO:0046620420.013
regulation of defense responseGO:00313471020.013
activation of jun kinase activityGO:000725730.013
eye developmentGO:00016543230.013
Mouse Fly
cellular amine metabolic processGO:0044106120.013
Rat
melanin metabolic processGO:0006582470.013
cell cell junction assemblyGO:0007043380.013
immune response activating signal transductionGO:000275720.013
synaptic growth at neuromuscular junctionGO:00511241190.013
purine nucleoside triphosphate catabolic processGO:00091461080.013
axon guidanceGO:00074112330.013
cellular response to transforming growth factor beta stimulusGO:0071560180.013
neuromuscular junction developmentGO:00075281490.013
larval developmentGO:00021641040.013
spindle localizationGO:0051653220.013
regulation of developmental pigmentationGO:0048070240.013
positive regulation of transcription dna templatedGO:00458932660.013
Worm
pole plasm protein localizationGO:0007318100.013
lateral inhibitionGO:00463312060.012
regulation of microtubule based processGO:0032886490.012
Human Mouse
actin polymerization or depolymerizationGO:0008154310.012
establishment of spindle localizationGO:0051293220.012
erbb signaling pathwayGO:0038127580.012
negative regulation of developmental growthGO:0048640640.012
substrate dependent cell migrationGO:000692930.012
regulation of ion transportGO:0043269390.012
intracellular transportGO:00469072280.012
Human Worm Fly
regulation of protein phosphorylationGO:0001932640.012
Human
cellular protein catabolic processGO:0044257830.012
Human Mouse
myoblast fusionGO:0007520430.012
positive regulation of protein bindingGO:003209210.012
regulation of synapse assemblyGO:0051963940.012
defense responseGO:00069523000.012
nucleocytoplasmic transportGO:0006913720.012
Human Worm
guanosine containing compound catabolic processGO:1901069740.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
Human
unidimensional cell growthGO:0009826150.012
sister chromatid segregationGO:0000819920.012
Human Mouse
posttranscriptional gene silencing by rnaGO:0035194450.012
regulation of ras protein signal transductionGO:0046578930.012
positive regulation of nucleotide catabolic processGO:0030813460.012
regulation of locomotionGO:0040012420.012
Human Mouse Worm
nucleoside triphosphate catabolic processGO:00091431080.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
Worm
cellular macromolecule catabolic processGO:00442651360.012
Human Mouse
cellular response to endogenous stimulusGO:0071495800.011
Rat
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.011
jnk cascadeGO:0007254500.011
morphogenesis of follicular epitheliumGO:0016333360.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
spermatogenesisGO:00072832000.011
regulation of neurogenesisGO:00507671580.011
pronuclear migrationGO:003504640.011
epithelium migrationGO:00901321480.011
epithelial cell morphogenesisGO:0003382250.011
cytoplasmic transport nurse cell to oocyteGO:0007303120.011
signal transduction by phosphorylationGO:00230141070.011
Mouse
immune effector processGO:0002252980.011
positive regulation of kinase activityGO:0033674250.011
regulation of neuron differentiationGO:00456641030.011
pole plasm oskar mrna localizationGO:0045451460.011
regulation of protein localizationGO:0032880760.011
Human Mouse
response to lipopolysaccharideGO:003249640.011

Apc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.017
Human
cancerDOID:16200.017
Human
organ system cancerDOID:005068600.012
Human