Drosophila melanogaster

183 known processes

ss (Dmel_CG6993)

spineless

(Aliases: SS,ssa,CG6993,AHR,Ss,Dmel\CG6993)

ss biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
leg disc developmentGO:0035218920.993
regionalizationGO:00030024160.986
eye antennal disc developmentGO:0035214600.974
transcription from rna polymerase ii promoterGO:00063663680.948
negative regulation of nucleic acid templated transcriptionGO:19035072400.945
negative regulation of nucleobase containing compound metabolic processGO:00459342610.942
positive regulation of nitrogen compound metabolic processGO:00511733540.941
Zebrafish Mouse
negative regulation of biosynthetic processGO:00098902770.931
regulation of cell differentiationGO:00455953020.919
imaginal disc derived leg morphogenesisGO:0007480800.918
imaginal disc derived leg segmentationGO:0036011260.916
negative regulation of nitrogen compound metabolic processGO:00511722650.912
positive regulation of gene expressionGO:00106282900.864
Zebrafish Mouse
imaginal disc derived appendage developmentGO:00487373990.857
courtship behaviorGO:0007619680.854
positive regulation of macromolecule biosynthetic processGO:00105572830.849
Zebrafish Mouse
positive regulation of macromolecule metabolic processGO:00106044050.825
Zebrafish Mouse
negative regulation of rna metabolic processGO:00512532510.825
appendage morphogenesisGO:00351073970.824
positive regulation of transcription dna templatedGO:00458932660.823
Zebrafish Mouse
sensory perception of mechanical stimulusGO:0050954720.820
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.802
leg disc morphogenesisGO:0007478800.795
regulation of epithelial cell proliferationGO:005067840.790
regulation of transcription from rna polymerase ii promoterGO:00063573780.788
taxisGO:00423303040.781
negative regulation of macromolecule biosynthetic processGO:00105582700.764
eye developmentGO:00016543230.755
central nervous system developmentGO:00074172010.741
axonogenesisGO:00074092900.729
neurological system processGO:00508773580.728
negative regulation of cellular metabolic processGO:00313243820.728
positive regulation of nucleobase containing compound metabolic processGO:00459353320.677
Zebrafish Mouse
kidney developmentGO:000182230.676
Mouse
multicellular organismal reproductive behaviorGO:00330571100.676
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.675
stem cell differentiationGO:00488631170.673
multi organism behaviorGO:00517051750.672
axon guidanceGO:00074112330.666
leg disc proximal distal pattern formationGO:000747990.660
regulation of multicellular organismal developmentGO:20000264140.658
positive regulation of biosynthetic processGO:00098913160.657
Zebrafish Mouse
sensory perceptionGO:00076001960.654
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.622
Zebrafish Mouse
positive regulation of rna metabolic processGO:00512542710.616
Zebrafish Mouse
response to organic substanceGO:00100332840.613
Zebrafish Mouse Rat
hindbrain developmentGO:003090220.612
brain developmentGO:00074201200.597
regulation of anatomical structure morphogenesisGO:00226032420.594
immune system processGO:00023763470.582
Human Mouse
chemotaxisGO:00069352490.575
eye morphogenesisGO:00485922600.573
positive regulation of nucleic acid templated transcriptionGO:19035082660.561
Zebrafish Mouse
positive regulation of cellular biosynthetic processGO:00313283160.558
Zebrafish Mouse
neuroblast differentiationGO:0014016290.556
antennal developmentGO:0007469250.553
imaginal disc derived wing morphogenesisGO:00074763370.537
post embryonic appendage morphogenesisGO:00351203850.535
cell deathGO:00082192790.518
Mouse
cell proliferationGO:00082832990.505
Human
negative regulation of cellular biosynthetic processGO:00313272770.505
dendrite morphogenesisGO:00488131990.499
neuron projection guidanceGO:00974852410.491
tissue morphogenesisGO:00487292970.486
Mouse
cardiovascular system developmentGO:0072358820.484
Mouse
renal tubule developmentGO:0061326640.482
positive regulation of rna biosynthetic processGO:19026802660.482
Zebrafish Mouse
reproductive behaviorGO:00190981220.479
axon developmentGO:00615642970.475
negative regulation of rna biosynthetic processGO:19026792400.474
single organism behaviorGO:00447083910.471
cell migrationGO:00164772380.443
deathGO:00162652840.397
Mouse
negative regulation of transcription dna templatedGO:00458922370.396
regulation of apoptotic processGO:00429811300.389
negative regulation of programmed cell deathGO:0043069720.387
imaginal disc pattern formationGO:0007447910.377
compound eye developmentGO:00487493070.377
proximal distal pattern formationGO:0009954150.376
dorsal ventral pattern formationGO:00099531330.373
epithelial cell differentiationGO:00308553220.372
sensory organ morphogenesisGO:00905962600.371
regulation of imaginal disc derived wing sizeGO:0044719200.371
negative regulation of gene expressionGO:00106293870.364
nephron tubule morphogenesisGO:007207830.357
cellular response to oxygen containing compoundGO:1901701790.347
Mouse
anterior posterior pattern specificationGO:00099521360.334
eye photoreceptor cell developmentGO:0042462810.333
gastrulationGO:0007369700.328
muscle tissue developmentGO:0060537300.307
Mouse
male courtship behaviorGO:0008049630.304
embryonic pattern specificationGO:00098801740.302
programmed cell deathGO:00125012570.292
cell motilityGO:00488702510.288
male mating behaviorGO:0060179700.274
renal system developmentGO:0072001720.267
Mouse
connective tissue developmentGO:006144830.265
muscle structure developmentGO:00610612240.260
epithelial tube morphogenesisGO:0060562880.256
Mouse
genital disc sexually dimorphic developmentGO:003526340.252
tube morphogenesisGO:00352391910.252
Mouse
regulation of nervous system developmentGO:00519602480.247
tube developmentGO:00352952440.245
Mouse
multi organism reproductive behaviorGO:00447051210.239
muscle organ developmentGO:00075171270.239
eye antennal disc morphogenesisGO:0007455340.237
dendrite developmentGO:00163582040.224
apoptotic process involved in morphogenesisGO:006056130.223
regulation of neurogenesisGO:00507671580.214
lateral inhibitionGO:00463312060.211
response to abiotic stimulusGO:00096283410.210
morphogenesis of an epitheliumGO:00020092760.210
Mouse
kidney morphogenesisGO:006099330.204
Mouse
kidney epithelium developmentGO:007207330.204
female sex differentiationGO:0046660200.200
Rat
dendrite guidanceGO:0070983210.199
respiratory system developmentGO:00605412130.197
telencephalon developmentGO:002153720.178
immune system developmentGO:0002520570.178
Mouse
wing disc morphogenesisGO:00074723440.176
embryonic organ developmentGO:0048568500.176
Mouse
regulation of cell proliferationGO:00421271630.169
Human
female gonad developmentGO:0008585120.168
Rat
peripheral nervous system developmentGO:0007422520.165
skin developmentGO:0043588650.164
neuron recognitionGO:00080381010.162
trunk segmentationGO:003529080.162
regulation of cell developmentGO:00602842150.161
wing disc pattern formationGO:0035222660.159
head developmentGO:00603221350.157
negative regulation of response to stimulusGO:00485852580.153
neuroblast developmentGO:0014019130.151
compound eye morphogenesisGO:00017452490.150
muscle cell fate commitmentGO:0042693140.150
hair cell differentiationGO:0035315470.149
notum cell fate specificationGO:003531050.149
positive regulation of developmental processGO:00510941430.149
nephron developmentGO:007200630.148
Mouse
epithelial cell developmentGO:00020642740.144
ovarian follicle cell developmentGO:00307072480.138
regulation of embryonic developmentGO:0045995680.137
camera type eye photoreceptor cell differentiationGO:006021920.137
cranial nerve developmentGO:002154510.135
regulation of programmed cell deathGO:00430671520.135
columnar cuboidal epithelial cell developmentGO:00020662490.132
cell recognitionGO:00080371020.131
circulatory system developmentGO:0072359820.131
Mouse
genital disc developmentGO:0035215440.130
neuroblast proliferationGO:0007405740.130
sex differentiationGO:0007548810.129
Rat
equator specificationGO:004531740.128
nephron morphogenesisGO:007202830.128
negative regulation of neuron deathGO:1901215180.125
segmentationGO:00352822070.125
spinal cord developmentGO:002151010.123
response to oxygen containing compoundGO:19017002000.123
Mouse Rat
terminal region determinationGO:0007362250.121
zygotic determination of anterior posterior axis embryoGO:0007354270.120
epidermis developmentGO:0008544650.120
neuron fate specificationGO:0048665120.118
mating behaviorGO:00076171060.115
stem cell proliferationGO:0072089880.113
regulation of cell deathGO:00109411730.112
Mouse
posttranscriptional regulation of gene expressionGO:00106081450.110
development of primary female sexual characteristicsGO:0046545120.106
Rat
segment specificationGO:0007379330.104
open tracheal system developmentGO:00074242040.104
neural retina developmentGO:000340740.104
appendage developmentGO:00487364010.103
regulation of r7 cell differentiationGO:0045676150.102
photoreceptor cell differentiationGO:00465301700.101
cellular response to chemical stimulusGO:00708871990.100
Zebrafish Mouse Rat
developmental growthGO:00485892800.098
Mouse
imaginal disc derived leg joint morphogenesisGO:0016348150.097
male courtship behavior veined wing extensionGO:0048065220.096
nephron epithelium developmentGO:007200930.096
single organism intracellular transportGO:19025822070.096
digestive tract developmentGO:00485651490.095
somatic muscle developmentGO:0007525660.094
matingGO:00076181200.092
mushroom body developmentGO:0016319700.091
locomotory behaviorGO:00076261760.088
regulation of stem cell proliferationGO:0072091400.088
imaginal disc derived appendage morphogenesisGO:00351143950.087
gland developmentGO:00487321910.087
Mouse
cellular response to organic substanceGO:00713101320.087
Zebrafish Mouse Rat
nephron epithelium morphogenesisGO:007208830.087
malpighian tubule developmentGO:0072002640.085
specification of segmental identity trunkGO:003529270.083
neural precursor cell proliferationGO:0061351750.082
feeding behaviorGO:0007631500.081
camera type eye developmentGO:004301040.081
Mouse
protein modification by small protein conjugation or removalGO:00706471060.078
Mouse
antennal morphogenesisGO:0048800140.076
embryonic morphogenesisGO:00485982060.075
digestive system developmentGO:00551231490.075
regulation of cell morphogenesisGO:00226041630.074
embryo development ending in birth or egg hatchingGO:00097921520.073
negative regulation of multicellular organismal processGO:00512411420.073
Mouse
anterior malpighian tubule developmentGO:0061327120.072
homeostatic processGO:00425921990.072
Mouse
nephron tubule developmentGO:007208030.072
anterior posterior axis specificationGO:00099481090.072
cardiocyte differentiationGO:0035051290.072
developmental maturationGO:00217001720.070
limb morphogenesisGO:003510810.070
chaeta morphogenesisGO:0008407420.070
cognitionGO:00508901410.069
chaeta developmentGO:0022416970.069
axis specificationGO:00097981670.068
development of primary sexual characteristicsGO:0045137500.068
Rat
memoryGO:0007613940.068
sensory perception of soundGO:0007605560.068
positive regulation of cell proliferationGO:0008284470.066
regulation of neuroblast proliferationGO:1902692340.065
epithelial cell proliferationGO:0050673150.065
regulation of neuron differentiationGO:00456641030.064
cell fate specificationGO:0001708710.064
retinal cone cell differentiationGO:004267020.062
neuron projection extensionGO:1990138320.061
regulation of epithelial cell differentiationGO:003085640.060
skeletal muscle organ developmentGO:0060538480.060
gliogenesisGO:0042063800.059
developmental cell growthGO:0048588520.059
determination of imaginal disc primordiumGO:0007445110.058
forebrain developmentGO:003090020.057
larval developmentGO:00021641040.056
muscle tissue morphogenesisGO:006041520.055
regulation of locomotionGO:0040012420.053
Worm
regulation of neuron projection developmentGO:0010975690.053
renal tubule morphogenesisGO:0061333440.052
photoreceptor cell fate specificationGO:004370490.052
malpighian tubule morphogenesisGO:0007443440.051
negative regulation of neurogenesisGO:0050768530.051
body morphogenesisGO:001017120.051
mesenchymal cell differentiationGO:004876210.051
reproductive structure developmentGO:0048608740.050
Mouse Rat
negative regulation of developmental processGO:00510932010.050
urogenital system developmentGO:0001655720.050
Mouse
organic substance transportGO:00717022570.049
positive regulation of response to stimulusGO:00485843230.049
learning or memoryGO:00076111410.048
female genitalia developmentGO:003054060.048
digestive tract morphogenesisGO:00485461270.048
wnt signaling pathwayGO:0016055980.048
cellular macromolecule localizationGO:00707272200.048
response to radiationGO:00093141550.048
nephron tubule formationGO:007207930.047
axon extensionGO:0048675320.047
limb developmentGO:006017310.046
tube formationGO:0035148210.045
dorsal ventral pattern formation imaginal discGO:0007450510.045
wing and notum subfield formationGO:0035309130.044
photoreceptor cell developmentGO:0042461960.044
reproductive system developmentGO:0061458740.044
Mouse Rat
negative regulation of cell differentiationGO:00455961430.043
regulation of response to stressGO:00801342000.043
localization of cellGO:00516742570.043
cellular protein modification processGO:00064644380.041
Mouse
response to external biotic stimulusGO:00432072930.040
regulation of immune system processGO:00026821760.040
Human
negative regulation of cell deathGO:0060548810.040
Mouse
eye photoreceptor cell differentiationGO:00017541450.040
cell type specific apoptotic processGO:0097285380.039
positive regulation of protein metabolic processGO:00512471280.038
Mouse
cuticle pattern formationGO:0035017270.038
skeletal muscle fiber developmentGO:004874130.038
neuron deathGO:0070997270.037
appendage segmentationGO:0035285260.035
regulation of behaviorGO:0050795750.035
heart developmentGO:0007507820.035
Mouse
blastoderm segmentationGO:00073501590.035
regulation of cellular component biogenesisGO:00440872010.035
Mouse
regulation of phosphorus metabolic processGO:00511742100.035
cell cell signaling involved in cell fate commitmentGO:00451682100.035
multi multicellular organism processGO:00447061230.034
negative regulation of nervous system developmentGO:0051961920.034
positive regulation of cell differentiationGO:0045597640.034
defense responseGO:00069523000.034
leg disc pattern formationGO:0035223110.033
cell fate determinationGO:0001709910.033
amine metabolic processGO:0009308120.033
hindgut morphogenesisGO:0007442580.033
regulation of cellular protein metabolic processGO:00322682430.032
Mouse
protein modification by small protein conjugationGO:0032446790.032
Mouse
mesenchymal cell developmentGO:001403110.032
response to alcoholGO:0097305950.032
Rat
mesoderm developmentGO:0007498780.032
muscle cell differentiationGO:00426921030.031
regulation of glial cell differentiationGO:004568510.031
regulation of wnt signaling pathwayGO:0030111680.031
positive regulation of nervous system developmentGO:0051962690.031
torso signaling pathwayGO:0008293210.031
regulation of axon extensionGO:003051680.031
embryonic hindgut morphogenesisGO:0048619480.031
response to lipidGO:0033993380.030
Rat
positive regulation of retinal cell programmed cell deathGO:004667090.030
regulation of cell projection organizationGO:0031344920.030
regulation of photoreceptor cell differentiationGO:0046532340.030
circadian behaviorGO:0048512760.030
growthGO:00400073590.029
Mouse
pigmentationGO:0043473750.029
regulation of cellular component sizeGO:0032535980.029
Mouse
stem cell developmentGO:0048864790.029
outflow tract morphogenesisGO:000315140.028
regulation of localizationGO:00328792750.028
retina development in camera type eyeGO:006004140.028
positive regulation of multicellular organismal processGO:00512401430.028
gonad developmentGO:0008406500.027
Rat
epidermal cell differentiationGO:0009913510.027
specification of organ identityGO:001009230.027
positive regulation of signalingGO:00230562430.026
response to acid chemicalGO:0001101250.026
multicellular organism growthGO:0035264460.026
positive regulation of cellular protein metabolic processGO:00322701180.025
Mouse
morphogenesis of embryonic epitheliumGO:0016331940.025
positive regulation of intracellular signal transductionGO:19025331160.025
stem cell divisionGO:0017145690.025
establishment of organelle localizationGO:00516561220.025
compound eye photoreceptor cell differentiationGO:00017511400.025
compound eye photoreceptor developmentGO:0042051780.025
regulation of neuron deathGO:1901214260.025
wing disc dorsal ventral pattern formationGO:0048190470.024
establishment of body hair planar orientationGO:004810510.024
neuron remodelingGO:0016322290.024
regulation of cell cycleGO:00517262910.024
cellular response to acid chemicalGO:007122980.024
apoptotic processGO:00069151590.024
negative regulation of cell proliferationGO:0008285690.024
epithelial cell migrationGO:00106311480.024
establishment of localization in cellGO:00516494020.023
signal releaseGO:0023061490.023
synaptic transmissionGO:00072682880.023
regulation of phosphatase activityGO:001092130.022
cell fate specification involved in pattern specificationGO:006057380.022
carbohydrate homeostasisGO:0033500120.022
formation of anatomical boundaryGO:0048859370.022
negative regulation of cell communicationGO:00106482230.022
carbohydrate derivative metabolic processGO:19011352170.022
proximal distal pattern formation imaginal discGO:0007449110.021
enzyme linked receptor protein signaling pathwayGO:00071671790.021
cellular component assembly involved in morphogenesisGO:00109271510.021
single organism cellular localizationGO:19025801800.021
cell growthGO:00160491080.021
germ cell migrationGO:0008354430.021
regulation of growthGO:00400082330.020
Mouse
negative regulation of apoptotic processGO:0043066630.020
negative regulation of neuron apoptotic processGO:0043524140.020
circadian rhythmGO:00076231050.020
Mouse
establishment of protein localizationGO:00451841630.020
embryonic axis specificationGO:00005781070.020
multicellular organismal homeostasisGO:0048871410.019
regulation of mitotic cell cycleGO:00073461900.019
lymph gland developmentGO:0048542280.019
specification of segmental identity headGO:0007380110.019
regulation of cellular catabolic processGO:00313291570.019
regulation of protein modification by small protein conjugation or removalGO:1903320250.019
Mouse
protein ubiquitinationGO:0016567700.018
cardiac muscle tissue developmentGO:004873890.018
positive regulation of cell communicationGO:00106472500.018
regulation of anatomical structure sizeGO:00900661630.018
Mouse
positive regulation of phosphate metabolic processGO:00459371390.018
neuron apoptotic processGO:0051402170.018
cell divisionGO:00513012480.018
convergent extension involved in gastrulationGO:006002720.018
peripheral nervous system neuron developmentGO:004893580.018
imaginal disc derived wing vein specificationGO:0007474480.017
hematopoietic progenitor cell differentiationGO:000224410.017
neuron fate commitmentGO:0048663500.017
positive regulation of neurogenesisGO:0050769410.017
mating behavior sex discriminationGO:004804770.017
actin filament bundle assemblyGO:0051017260.017
anatomical structure homeostasisGO:0060249970.017
response to decreased oxygen levelsGO:0036293580.016
central nervous system neuron differentiationGO:002195380.016
glial cell differentiationGO:0010001350.016
adult behaviorGO:00305341370.016
regulation of notch signaling pathwayGO:00085931000.016
cell maturationGO:00484691440.016
protein localizationGO:00081042840.016
establishment of spindle orientationGO:0051294180.016
embryonic development via the syncytial blastodermGO:00017001480.016
determination of genital disc primordiumGO:0035225100.016
larval midgut histolysisGO:0035069220.016
cellular response to lipidGO:0071396200.016
Rat
response to oxygen levelsGO:0070482590.016
nerve developmentGO:002167560.016
gene silencingGO:00164581380.016
phagocytosisGO:00069092150.015
organic substance catabolic processGO:19015753080.015
cell adhesionGO:00071551360.015
imaginal disc derived female genitalia developmentGO:000748660.015
protein modification processGO:00362114380.015
Mouse
cuticle pigmentationGO:0048067220.015
amnioserosa maintenanceGO:004666550.015
macromolecule catabolic processGO:00090571610.015
immune responseGO:00069552460.015
regulation of reproductive processGO:2000241540.015
fusion cell fate specificationGO:003515640.015
positive regulation of cellular component organizationGO:00511301560.015
Mouse
vesicle mediated transportGO:00161923810.014
regulation of cell morphogenesis involved in differentiationGO:0010769610.014
compound eye cone cell differentiationGO:0042675130.014
regulation of protein metabolic processGO:00512462560.014
Mouse
carbohydrate derivative biosynthetic processGO:1901137850.014
ocellus developmentGO:000805640.014
muscle cell fate specificationGO:004269470.014
agingGO:00075681430.014
gonad morphogenesisGO:003526270.014
camera type eye morphogenesisGO:004859320.014
positive regulation of signal transductionGO:00099672230.014
cellular response to abiotic stimulusGO:0071214580.014
endocytosisGO:00068973100.014
positive regulation of translationGO:0045727120.014
cellular macromolecular complex assemblyGO:00346221530.013
Mouse
carbohydrate metabolic processGO:0005975820.013
positive regulation of cell motilityGO:200014730.013
cardioblast differentiationGO:0010002200.013
positive regulation of cell migrationGO:003033520.013
anterior posterior axis specification embryoGO:00085951030.013
developmental growth involved in morphogenesisGO:0060560650.013
Mouse
muscle organ morphogenesisGO:004864470.013
epithelium migrationGO:00901321480.013
regulation of molecular functionGO:00650092170.013
translationGO:0006412690.013
cellular catabolic processGO:00442483720.013
ameboidal type cell migrationGO:00016671510.013
central nervous system segmentationGO:003528350.013
cytoplasmic transportGO:00164821300.013
cellular protein localizationGO:00346131600.012
regulation of muscle cell differentiationGO:005114780.012
intracellular transportGO:00469072280.012
polarized epithelial cell differentiationGO:0030859100.012
dna metabolic processGO:00062592270.012
germ line stem cell maintenanceGO:0030718500.012
regulation of protein localizationGO:0032880760.012
protein targeting to nucleusGO:0044744510.012
mitotic cell cycle phase transitionGO:00447721380.012
brain morphogenesisGO:0048854160.012
chromosome organizationGO:00512763600.012
protein dna complex assemblyGO:0065004630.012
Mouse
chorion containing eggshell formationGO:00073041050.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
germ line stem cell divisionGO:0042078250.012
mesenchyme developmentGO:006048590.011
response to hypoxiaGO:0001666530.011
carboxylic acid metabolic processGO:0019752920.011
regulation of defense responseGO:00313471020.011
response to glucoseGO:000974920.011
negative regulation of epithelial cell proliferationGO:005068040.011
enteroendocrine cell differentiationGO:003588310.011
skeletal muscle tissue developmentGO:0007519130.011
regulation of system processGO:0044057360.011
Mouse
positive regulation of protein modification processGO:0031401580.011
Mouse
positive regulation of neuron apoptotic processGO:004352510.011
regulation of protein modification processGO:00313991120.011
Mouse
response to woundingGO:0009611940.011
morphogenesis of a branching epitheliumGO:0061138450.011
Mouse
innate immune responseGO:00450871440.011
response to monosaccharideGO:003428440.011
chemosensory behaviorGO:00076351060.011
nuclear transportGO:0051169720.011
cellular response to carbohydrate stimulusGO:007132240.011
regulation of organelle organizationGO:00330431960.011
nuclear importGO:0051170510.011
muscle system processGO:0003012210.011
larval somatic muscle developmentGO:0007526190.010
negative regulation of cellular component organizationGO:00511291080.010
anterior posterior pattern specification imaginal discGO:0007448160.010
synapse assemblyGO:00074161430.010
epithelial tube formationGO:007217570.010
morphogenesis of a branching structureGO:0001763450.010
Mouse
hemocyte differentiationGO:0042386380.010
response to other organismGO:00517072930.010

ss disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.249
nervous system diseaseDOID:86300.058
cardiovascular system diseaseDOID:128700.015