Drosophila melanogaster

6 known processes

Hmt-1 (Dmel_CG4225)

Heavy metal tolerance factor 1

(Aliases: hmt-1,EP(3)3387,Dmel\CG4225,CG4225)

Hmt-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vesicle mediated transportGO:00161923810.065
organonitrogen compound metabolic processGO:19015643180.060
Human
small molecule metabolic processGO:00442813050.057
Human
organophosphate metabolic processGO:00196371950.057
Human
ion transportGO:00068111450.057
cellular protein modification processGO:00064644380.049
cation transmembrane transportGO:0098655880.047
catabolic processGO:00090564090.046
Human
single organism catabolic processGO:00447122280.045
Human
carbohydrate derivative metabolic processGO:19011352170.042
Human
cellular catabolic processGO:00442483720.040
Human
lipid metabolic processGO:00066291210.039
organic substance catabolic processGO:19015753080.037
Human
organic substance transportGO:00717022570.037
Human
ribonucleotide metabolic processGO:00092591450.036
Human
homeostatic processGO:00425921990.035
response to abiotic stimulusGO:00096283410.035
transmembrane transportGO:00550851390.034
Human
glycosyl compound catabolic processGO:19016581120.034
Human
regulation of localizationGO:00328792750.033
organonitrogen compound biosynthetic processGO:19015661170.031
Human
cation transportGO:00068121100.029
purine ribonucleoside metabolic processGO:00461281270.028
Human
spermatogenesisGO:00072832000.028
nuclear divisionGO:00002803320.028
carboxylic acid metabolic processGO:0019752920.028
protein modification processGO:00362114380.028
intracellular transportGO:00469072280.027
metal ion transportGO:0030001740.027
aromatic compound catabolic processGO:00194391660.027
Human
purine nucleoside triphosphate catabolic processGO:00091461080.027
Human
phagocytosisGO:00069092150.026
macromolecular complex assemblyGO:00650032560.026
ion transmembrane transportGO:00342201220.026
endocytosisGO:00068973100.025
cellular amino acid metabolic processGO:0006520610.025
compound eye developmentGO:00487493070.025
carbohydrate derivative catabolic processGO:19011361180.024
Human
establishment of localization in cellGO:00516494020.024
organonitrogen compound catabolic processGO:19015651280.024
Human
regulation of cellular catabolic processGO:00313291570.024
ubiquitin dependent protein catabolic processGO:0006511780.023
purine nucleoside triphosphate metabolic processGO:00091441190.023
Human
response to oxygen containing compoundGO:19017002000.023
single organism membrane organizationGO:0044802930.023
glycerophospholipid metabolic processGO:0006650230.023
connective tissue developmentGO:006144830.023
single organism intracellular transportGO:19025822070.023
glycerolipid metabolic processGO:0046486340.023
organophosphate catabolic processGO:00464341120.022
Human
oxoacid metabolic processGO:00434361030.022
regulation of intracellular signal transductionGO:19025312360.022
cellular lipid metabolic processGO:0044255830.022
protein modification by small protein conjugation or removalGO:00706471060.022
organelle fusionGO:0048284460.022
mitotic nuclear divisionGO:00070672130.022
purine ribonucleoside triphosphate catabolic processGO:00092071080.022
Human
positive regulation of molecular functionGO:00440931360.022
regulation of transportGO:00510491810.021
nucleobase containing compound catabolic processGO:00346551650.021
Human
regulation of catabolic processGO:00098941700.021
regulation of cell cycleGO:00517262910.021
single organism biosynthetic processGO:00447112060.021
purine containing compound catabolic processGO:00725231120.021
Human
appendage morphogenesisGO:00351073970.021
ribonucleoside triphosphate metabolic processGO:00091991190.021
Human
ribonucleoside triphosphate catabolic processGO:00092031080.020
Human
membrane organizationGO:00610241120.020
purine containing compound metabolic processGO:00725211550.020
Human
response to other organismGO:00517072930.020
nucleobase containing small molecule metabolic processGO:00550861740.020
Human
regulation of phosphorus metabolic processGO:00511742100.020
nucleoside triphosphate catabolic processGO:00091431080.020
Human
ribonucleoside metabolic processGO:00091191270.020
Human
protein complex assemblyGO:00064612000.020
protein modification by small protein conjugationGO:0032446790.019
purine ribonucleoside catabolic processGO:00461301120.019
Human
cell divisionGO:00513012480.019
purine nucleotide metabolic processGO:00061631460.019
Human
cellular response to dna damage stimulusGO:00069742230.019
negative regulation of signalingGO:00230572190.019
regulation of programmed cell deathGO:00430671520.019
regulation of catalytic activityGO:00507901850.019
response to external biotic stimulusGO:00432072930.018
proteolysisGO:00065081920.018
glycosyl compound metabolic processGO:19016571270.018
Human
purine ribonucleoside triphosphate metabolic processGO:00092051190.018
Human
ribonucleoside catabolic processGO:00424541120.018
Human
developmental growthGO:00485892800.018
post embryonic appendage morphogenesisGO:00351203850.018
organelle fissionGO:00482853400.018
purine ribonucleotide catabolic processGO:00091541090.018
Human
imaginal disc derived wing morphogenesisGO:00074763370.018
cation homeostasisGO:0055080510.018
deathGO:00162652840.018
intracellular signal transductionGO:00355563000.018
protein maturationGO:0051604710.018
anion transportGO:0006820410.017
nucleoside phosphate metabolic processGO:00067531620.017
Human
sodium dependent phosphate transportGO:004434120.017
regulation of small gtpase mediated signal transductionGO:0051056930.017
detection of stimulusGO:00516061560.017
purine nucleotide catabolic processGO:00061951090.017
Human
cellular homeostasisGO:0019725800.017
inorganic cation transmembrane transportGO:0098662610.017
inorganic ion transmembrane transportGO:0098660730.017
protein complex biogenesisGO:00702712010.017
organic acid metabolic processGO:00060821030.017
purine nucleoside catabolic processGO:00061521120.017
Human
regulation of molecular functionGO:00650092170.017
ribonucleotide catabolic processGO:00092611090.017
Human
purine nucleoside metabolic processGO:00422781270.016
Human
negative regulation of signal transductionGO:00099682060.016
translationGO:0006412690.016
lipid biosynthetic processGO:0008610460.016
nucleotide metabolic processGO:00091171610.016
Human
cellular macromolecule localizationGO:00707272200.016
protein localizationGO:00081042840.016
response to lipopolysaccharideGO:003249640.016
nucleotide catabolic processGO:00091661090.016
Human
positive regulation of nucleobase containing compound metabolic processGO:00459353320.016
organic cyclic compound catabolic processGO:19013611680.016
Human
programmed cell deathGO:00125012570.015
atp metabolic processGO:0046034490.015
Human
modification dependent protein catabolic processGO:0019941780.015
nucleoside metabolic processGO:00091161270.015
Human
cell deathGO:00082192790.015
regionalizationGO:00030024160.015
ras protein signal transductionGO:0007265880.015
l amino acid importGO:004309220.015
ion homeostasisGO:0050801550.015
wing disc morphogenesisGO:00074723440.015
proteolysis involved in cellular protein catabolic processGO:0051603830.015
response to bacteriumGO:00096171980.014
protein catabolic processGO:00301631010.014
response to organic substanceGO:00100332840.014
nucleoside triphosphate metabolic processGO:00091411200.014
Human
cellular macromolecule catabolic processGO:00442651360.014
heterocycle catabolic processGO:00467001660.014
Human
chromosome organizationGO:00512763600.014
biological adhesionGO:00226101380.014
regulation of cellular component biogenesisGO:00440872010.014
defense response to bacteriumGO:00427421780.014
macromolecule catabolic processGO:00090571610.014
ribose phosphate metabolic processGO:00196931450.014
Human
regulation of phosphate metabolic processGO:00192202100.014
dna metabolic processGO:00062592270.014
negative regulation of cellular metabolic processGO:00313243820.014
positive regulation of response to stimulusGO:00485843230.013
response to biotic stimulusGO:00096072940.013
regulation of cell deathGO:00109411730.013
small gtpase mediated signal transductionGO:0007264880.013
cellular response to chemical stimulusGO:00708871990.013
cell migrationGO:00164772380.013
nucleoside phosphate catabolic processGO:19012921100.013
Human
purine ribonucleotide metabolic processGO:00091501450.013
Human
phosphorylationGO:00163102940.013
cellular nitrogen compound catabolic processGO:00442701650.013
Human
nitrogen compound transportGO:0071705850.013
Human
regulation of ras protein signal transductionGO:0046578930.013
positive regulation of signal transductionGO:00099672230.013
growthGO:00400073590.013
detection of chemical stimulusGO:0009593930.013
appendage developmentGO:00487364010.013
positive regulation of phosphate metabolic processGO:00459371390.012
membrane fusionGO:0061025420.012
positive regulation of phosphorus metabolic processGO:00105621390.012
male gamete generationGO:00482322010.012
cellular protein catabolic processGO:0044257830.012
negative regulation of cell communicationGO:00106482230.012
positive regulation of lipid storageGO:001088440.012
endomembrane system organizationGO:00102561190.012
regulation of protein metabolic processGO:00512462560.012
negative regulation of intracellular signal transductionGO:1902532570.012
response to alcoholGO:0097305950.012
defense response to other organismGO:00985422250.012
forebrain developmentGO:003090020.012
metal ion homeostasisGO:0055065440.012
cytoplasmic transportGO:00164821300.012
compound eye morphogenesisGO:00017452490.012
modification dependent macromolecule catabolic processGO:0043632790.012
carbohydrate derivative biosynthetic processGO:1901137850.012
positive regulation of cell communicationGO:00106472500.012
chemical homeostasisGO:0048878920.012
positive regulation of catabolic processGO:00098961050.012
positive regulation of cellular catabolic processGO:0031331950.011
response to nutrient levelsGO:00316671140.011
guanosine containing compound metabolic processGO:1901068740.011
protein transportGO:00150311550.011
imaginal disc derived appendage morphogenesisGO:00351143950.011
monocarboxylic acid transportGO:001571830.011
gland developmentGO:00487321910.011
protein ubiquitinationGO:0016567700.011
phosphate ion transportGO:000681740.011
positive regulation of signalingGO:00230562430.011
dorsal ventral pattern formationGO:00099531330.011
signal transduction by phosphorylationGO:00230141070.011
response to radiationGO:00093141550.011
regulation of growthGO:00400082330.011
synaptic transmissionGO:00072682880.011
imaginal disc derived appendage developmentGO:00487373990.011
maintenance of locationGO:0051235730.011
androgen metabolic processGO:000820910.011
regulation of organelle organizationGO:00330431960.010
positive regulation of catalytic activityGO:00430851180.010
body morphogenesisGO:001017120.010
nucleoside catabolic processGO:00091641120.010
Human
establishment of protein localizationGO:00451841630.010
oocyte constructionGO:00073081120.010
response to organic cyclic compoundGO:0014070890.010
cellular response to lipopolysaccharideGO:007122230.010
cellular amine metabolic processGO:0044106120.010
imaginal disc derived wing margin morphogenesisGO:0008587410.010
regulation of cellular localizationGO:00603411360.010
ethanolamine containing compound metabolic processGO:004243940.010
regulation of anatomical structure sizeGO:00900661630.010

Hmt-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.078
nervous system diseaseDOID:86300.037
central nervous system diseaseDOID:33100.014
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
disease of metabolismDOID:001466700.011
neurodegenerative diseaseDOID:128900.011
inherited metabolic disorderDOID:65500.010
eye diseaseDOID:561400.010