Drosophila melanogaster

64 known processes

elB (Dmel_CG4220)

elbow B

(Aliases: el,el[B],BG:DS06238.3,CG4220,P10,elb,elbow,Dmel\CG4220)

elB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
open tracheal system developmentGO:00074242040.745
regulation of transcription from rna polymerase ii promoterGO:00063573780.681
epithelial tube morphogenesisGO:0060562880.662
Fly
regulation of multicellular organismal developmentGO:20000264140.636
Human
morphogenesis of a branching epitheliumGO:0061138450.607
Fly
negative regulation of biosynthetic processGO:00098902770.588
Human Zebrafish
negative regulation of nucleic acid templated transcriptionGO:19035072400.559
Human Zebrafish
transcription from rna polymerase ii promoterGO:00063663680.532
respiratory system developmentGO:00605412130.524
branching involved in open tracheal system developmentGO:0060446450.493
Fly
positive regulation of biosynthetic processGO:00098913160.412
positive regulation of nucleic acid templated transcriptionGO:19035082660.400
stem cell differentiationGO:00488631170.368
morphogenesis of a branching structureGO:0001763450.346
Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.337
Human Zebrafish
positive regulation of nucleobase containing compound metabolic processGO:00459353320.333
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.317
positive regulation of transcription dna templatedGO:00458932660.305
circulatory system developmentGO:0072359820.300
negative regulation of transcription dna templatedGO:00458922370.281
Human Zebrafish
positive regulation of rna biosynthetic processGO:19026802660.268
dendrite developmentGO:00163582040.242
negative regulation of cellular metabolic processGO:00313243820.235
Human Zebrafish
negative regulation of cellular biosynthetic processGO:00313272770.232
Human Zebrafish
branching morphogenesis of an epithelial tubeGO:0048754450.232
Fly
positive regulation of rna metabolic processGO:00512542710.231
morphogenesis of an epitheliumGO:00020092760.224
Fly
compound eye developmentGO:00487493070.213
regulation of cellular protein metabolic processGO:00322682430.211
Zebrafish
kidney epithelium developmentGO:007207330.191
positive regulation of macromolecule metabolic processGO:00106044050.181
Zebrafish
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.179
proteolysisGO:00065081920.176
negative regulation of macromolecule biosynthetic processGO:00105582700.172
Human Zebrafish
positive regulation of macromolecule biosynthetic processGO:00105572830.170
regulation of cell proliferationGO:00421271630.166
Human
sensory organ morphogenesisGO:00905962600.162
stem cell developmentGO:0048864790.157
eye antennal disc developmentGO:0035214600.157
positive regulation of nitrogen compound metabolic processGO:00511733540.156
regulation of cell developmentGO:00602842150.154
eye developmentGO:00016543230.148
tube developmentGO:00352952440.145
Fly
cell proliferationGO:00082832990.143
neural precursor cell proliferationGO:0061351750.132
Mouse
tissue morphogenesisGO:00487292970.132
Fly
chromosome organizationGO:00512763600.130
Zebrafish
nephron morphogenesisGO:007202830.122
negative regulation of nitrogen compound metabolic processGO:00511722650.121
Human Zebrafish
epithelial cell differentiationGO:00308553220.121
Human
regulation of cell differentiationGO:00455953020.117
stem cell maintenanceGO:0019827670.116
dendrite morphogenesisGO:00488131990.116
positive regulation of cellular component organizationGO:00511301560.114
Zebrafish
cell maturationGO:00484691440.111
positive regulation of cellular biosynthetic processGO:00313283160.111
protein complex biogenesisGO:00702712010.109
nephron developmentGO:007200630.108
appendage developmentGO:00487364010.106
negative regulation of rna biosynthetic processGO:19026792400.105
Human Zebrafish
molting cycleGO:0042303560.102
response to abiotic stimulusGO:00096283410.095
positive regulation of developmental processGO:00510941430.087
Human
positive regulation of gene expressionGO:00106282900.086
regulation of protein metabolic processGO:00512462560.081
Zebrafish
gastrulation involving germ band extensionGO:0010004360.077
vesicle mediated transportGO:00161923810.075
nephron epithelium developmentGO:007200930.070
limb developmentGO:006017310.070
dna metabolic processGO:00062592270.069
regulation of response to stressGO:00801342000.069
positive regulation of compound eye retinal cell programmed cell deathGO:004667290.067
positive regulation of cellular protein metabolic processGO:00322701180.067
Zebrafish
cellular response to fibroblast growth factor stimulusGO:0044344100.065
negative regulation of cell cycleGO:00457861160.064
epithelial cell migrationGO:00106311480.063
positive regulation of protein metabolic processGO:00512471280.062
Zebrafish
columnar cuboidal epithelial cell differentiationGO:00020652560.061
cellular protein modification processGO:00064644380.060
Zebrafish
brain developmentGO:00074201200.059
Zebrafish Fly
cell divisionGO:00513012480.059
macromolecular complex assemblyGO:00650032560.057
protein modification processGO:00362114380.057
Zebrafish
regulation of steroid metabolic processGO:001921820.056
regulation of cellular ketone metabolic processGO:001056530.055
negative regulation of signalingGO:00230572190.054
kidney developmentGO:000182230.054
programmed cell deathGO:00125012570.053
regulation of protein modification processGO:00313991120.052
Zebrafish
ovarian follicle cell developmentGO:00307072480.051
rna splicing via transesterification reactionsGO:0000375730.050
negative regulation of smoothened signaling pathwayGO:0045879160.050
small gtpase mediated signal transductionGO:0007264880.050
taxisGO:00423303040.049
regulation of transportGO:00510491810.049
negative regulation of response to stimulusGO:00485852580.049
connective tissue developmentGO:006144830.049
urogenital system developmentGO:0001655720.049
regulation of chromosome organizationGO:0033044640.048
Zebrafish
cellular ketone metabolic processGO:0042180240.047
chromatin organizationGO:00063252070.046
Zebrafish
purine ribonucleotide catabolic processGO:00091541090.046
mrna splicing via spliceosomeGO:0000398730.045
macromolecule deacylationGO:0098732110.045
Zebrafish
regulation of anatomical structure morphogenesisGO:00226032420.045
regulation of cellular amino acid metabolic processGO:000652100.044
endocytosisGO:00068973100.043
nucleoside metabolic processGO:00091161270.043
embryonic organ developmentGO:0048568500.042
Zebrafish
cellular response to extracellular stimulusGO:0031668640.041
skin developmentGO:0043588650.041
bmp signaling pathwayGO:0030509270.041
positive regulation of signal transductionGO:00099672230.041
positive regulation of multicellular organismal processGO:00512401430.041
Human
kidney morphogenesisGO:006099330.040
cellular response to organic substanceGO:00713101320.040
Human
positive regulation of programmed cell deathGO:0043068620.039
protein complex assemblyGO:00064612000.038
organonitrogen compound metabolic processGO:19015643180.038
imaginal disc derived wing vein specificationGO:0007474480.037
genital disc developmentGO:0035215440.037
regulation of intracellular signal transductionGO:19025312360.037
glycosyl compound metabolic processGO:19016571270.037
negative regulation of molecular functionGO:0044092510.037
ion transportGO:00068111450.037
cellular response to chemical stimulusGO:00708871990.036
Human
positive regulation of cell communicationGO:00106472500.036
rna splicingGO:0008380830.036
intracellular signal transductionGO:00355563000.035
epithelial cell developmentGO:00020642740.035
regulation of cellular response to growth factor stimulusGO:0090287130.035
Human
histone modificationGO:00165701060.035
Zebrafish
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.034
oocyte developmentGO:00485991240.034
neuron projection guidanceGO:00974852410.034
developmental maturationGO:00217001720.034
cellular response to growth factor stimulusGO:0071363300.034
Human
response to endogenous stimulusGO:00097191190.033
Human
endodermal cell differentiationGO:003598730.033
amine metabolic processGO:0009308120.033
compound eye morphogenesisGO:00017452490.032
cellular macromolecule localizationGO:00707272200.032
regulation of organelle organizationGO:00330431960.032
Zebrafish
negative regulation of gene expressionGO:00106293870.032
chemotaxisGO:00069352490.032
oxoacid metabolic processGO:00434361030.032
embryonic heart tube developmentGO:0035050220.032
renal tubule developmentGO:0061326640.031
regulation of hydrolase activityGO:0051336970.031
deathGO:00162652840.031
positive regulation of catalytic activityGO:00430851180.031
small molecule metabolic processGO:00442813050.030
cranial nerve developmentGO:002154510.030
forebrain developmentGO:003090020.030
anterior posterior pattern specificationGO:00099521360.029
immune responseGO:00069552460.029
mitotic nuclear divisionGO:00070672130.029
positive regulation of cell deathGO:0010942690.029
organelle assemblyGO:00709251980.029
smoothened signaling pathwayGO:0007224490.029
epithelial cell morphogenesisGO:0003382250.029
regulation of cellular amine metabolic processGO:003323830.028
regulation of localizationGO:00328792750.028
spiracle morphogenesis open tracheal systemGO:0035277220.028
embryonic hindgut morphogenesisGO:0048619480.028
regulation of molecular functionGO:00650092170.027
regulation of programmed cell deathGO:00430671520.027
actin cytoskeleton organizationGO:00300362060.026
phosphorylationGO:00163102940.026
developmental growthGO:00485892800.026
imaginal disc derived appendage developmentGO:00487373990.026
positive regulation of cellular component biogenesisGO:0044089800.026
axon guidanceGO:00074112330.026
eye photoreceptor cell differentiationGO:00017541450.026
regulation of anatomical structure sizeGO:00900661630.026
positive regulation of signalingGO:00230562430.026
negative regulation of cell communicationGO:00106482230.026
covalent chromatin modificationGO:00165691060.025
Zebrafish
regulation of cell morphogenesisGO:00226041630.025
response to organic substanceGO:00100332840.025
Human
organic substance transportGO:00717022570.025
organic acid metabolic processGO:00060821030.024
nitrogen compound transportGO:0071705850.024
regulation of cell deathGO:00109411730.024
negative regulation of rna metabolic processGO:00512532510.024
Human Zebrafish
rho protein signal transductionGO:0007266140.024
response to fibroblast growth factorGO:0071774100.024
purine nucleoside triphosphate catabolic processGO:00091461080.024
regulation of vesicle mediated transportGO:0060627590.023
regionalizationGO:00030024160.023
protein modification by small protein conjugation or removalGO:00706471060.023
nephron epithelium morphogenesisGO:007208830.023
epidermal cell differentiationGO:0009913510.023
defense responseGO:00069523000.023
negative regulation of developmental processGO:00510932010.023
ras protein signal transductionGO:0007265880.022
renal system developmentGO:0072001720.022
positive regulation of cell differentiationGO:0045597640.022
ribonucleoside catabolic processGO:00424541120.022
single organism behaviorGO:00447083910.022
purine ribonucleoside triphosphate metabolic processGO:00092051190.022
positive regulation of molecular functionGO:00440931360.022
regulation of neuron differentiationGO:00456641030.021
limb morphogenesisGO:003510810.021
regulation of immune system processGO:00026821760.021
regulation of rho protein signal transductionGO:0035023200.021
phagocytosisGO:00069092150.021
regulation of bmp signaling pathwayGO:0030510230.021
negative regulation of cellular protein metabolic processGO:0032269850.021
carbohydrate derivative metabolic processGO:19011352170.021
organ inductionGO:000175930.021
ocellus developmentGO:000805640.021
Fly
regulation of small gtpase mediated signal transductionGO:0051056930.021
epithelial cell migration open tracheal systemGO:0007427320.020
cellular homeostasisGO:0019725800.020
single organism biosynthetic processGO:00447112060.020
hemopoiesisGO:0030097460.020
regulation of phosphorus metabolic processGO:00511742100.020
retinal cell programmed cell deathGO:0046666250.020
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.020
regulation of peptidase activityGO:0052547390.019
regulation of proteolysisGO:0030162870.019
regulation of growthGO:00400082330.019
regulation of phosphate metabolic processGO:00192202100.019
skeletal muscle adaptationGO:004350110.019
regulation of smoothened signaling pathwayGO:0008589280.019
myotube cell developmentGO:001490430.019
regulation of mrna splicing via spliceosomeGO:0048024640.019
endodermal cell fate commitmentGO:000171130.019
axon developmentGO:00615642970.018
organ growthGO:0035265560.018
stem cell proliferationGO:0072089880.018
maintenance of locationGO:0051235730.018
regulation of dendrite developmentGO:0050773370.018
regulation of cell shapeGO:00083601130.018
cuticle developmentGO:0042335860.017
alternative mrna splicing via spliceosomeGO:0000380600.017
pattern recognition receptor signaling pathwayGO:000222120.017
photoreceptor cell differentiationGO:00465301700.017
post embryonic appendage morphogenesisGO:00351203850.017
negative regulation of signal transductionGO:00099682060.017
purine ribonucleoside triphosphate catabolic processGO:00092071080.017
organic substance catabolic processGO:19015753080.017
specification of organ identityGO:001009230.016
regulation of neuron projection developmentGO:0010975690.016
branch fusion open tracheal systemGO:0035147170.016
regulation of myotube differentiationGO:001083060.016
regulation of ras protein signal transductionGO:0046578930.016
negative regulation of protein metabolic processGO:0051248850.016
appendage morphogenesisGO:00351073970.016
regulation of secretion by cellGO:1903530390.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.016
single organism cell adhesionGO:0098602470.016
cell deathGO:00082192790.016
synaptic transmissionGO:00072682880.016
purine containing compound catabolic processGO:00725231120.016
positive regulation of transportGO:0051050920.016
cellular protein localizationGO:00346131600.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
cellular response to endogenous stimulusGO:0071495800.015
Human
purine ribonucleoside catabolic processGO:00461301120.015
mesodermal cell fate specificationGO:000750120.015
tube morphogenesisGO:00352391910.015
Fly
positive regulation of cell proliferationGO:0008284470.015
Human
mrna processingGO:00063971040.015
negative regulation of nucleobase containing compound metabolic processGO:00459342610.015
Human Zebrafish
chaeta developmentGO:0022416970.015
nucleobase containing small molecule metabolic processGO:00550861740.015
nucleotide catabolic processGO:00091661090.015
cellular transition metal ion homeostasisGO:004691690.015
inorganic ion transmembrane transportGO:0098660730.015
response to other organismGO:00517072930.015
nephron tubule morphogenesisGO:007207830.015
hindgut developmentGO:0061525580.015
outflow tract morphogenesisGO:000315140.014
cuticle pigmentationGO:0048067220.014
regulation of cell divisionGO:0051302720.014
regulation of protein kinase activityGO:0045859510.014
regulation of organ formationGO:000315630.014
regulation of neurogenesisGO:00507671580.014
nucleoside catabolic processGO:00091641120.014
oocyte differentiationGO:00099941450.014
establishment of localization in cellGO:00516494020.014
positive regulation of protein modification processGO:0031401580.014
Zebrafish
eye morphogenesisGO:00485922600.014
positive regulation of histone deacetylationGO:003106520.014
Zebrafish
stem cell divisionGO:0017145690.014
positive regulation of lipid metabolic processGO:004583440.014
ribonucleoside triphosphate metabolic processGO:00091991190.014
agingGO:00075681430.014
organophosphate metabolic processGO:00196371950.013
synaptic vesicle localizationGO:0097479530.013
heart developmentGO:0007507820.013
cellular amine metabolic processGO:0044106120.013
intracellular transportGO:00469072280.013
mrna metabolic processGO:00160711240.013
histone deacetylationGO:001657590.013
Zebrafish
response to bacteriumGO:00096171980.013
jak stat cascadeGO:0007259490.013
body morphogenesisGO:001017120.013
cellular nitrogen compound catabolic processGO:00442701650.013
inorganic cation transmembrane transportGO:0098662610.013
positive regulation of phosphorus metabolic processGO:00105621390.013
protein phosphorylationGO:00064681690.013
purine ribonucleoside metabolic processGO:00461281270.013
compound eye retinal cell programmed cell deathGO:0046667230.013
carboxylic acid metabolic processGO:0019752920.013
regulation of stem cell proliferationGO:0072091400.013
reproductive system developmentGO:0061458740.013
mesenchymal cell developmentGO:001403110.013
protein modification by small protein conjugationGO:0032446790.012
homeostatic processGO:00425921990.012
chemical homeostasisGO:0048878920.012
glycosyl compound catabolic processGO:19016581120.012
regulation of developmental pigmentationGO:0048070240.012
regulation of histone modificationGO:0031056200.012
Zebrafish
regulation of lipid biosynthetic processGO:004689060.012
negative regulation of cell differentiationGO:00455961430.012
cardiovascular system developmentGO:0072358820.012
gastrulationGO:0007369700.012
digestive tract developmentGO:00485651490.012
muscle tissue developmentGO:0060537300.012
positive regulation of secretionGO:0051047220.012
purine nucleoside metabolic processGO:00422781270.012
peptidyl amino acid modificationGO:00181931050.012
regulation of alternative mrna splicing via spliceosomeGO:0000381600.012
gastrulation with mouth forming firstGO:0001703360.012
cell fate specificationGO:0001708710.012
positive regulation of organelle organizationGO:0010638650.012
Zebrafish
central nervous system developmentGO:00074172010.012
Zebrafish Fly
hematopoietic progenitor cell differentiationGO:000224410.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.012
immune system developmentGO:0002520570.011
positive regulation of proteolysisGO:0045862520.011
negative regulation of cell proliferationGO:0008285690.011
Human
positive regulation of rho gtpase activityGO:0032321190.011
regulation of kinase activityGO:0043549530.011
imaginal disc derived wing morphogenesisGO:00074763370.011
blastoderm segmentationGO:00073501590.011
positive regulation of hydrolase activityGO:0051345780.011
regulation of chromatin modificationGO:1903308280.011
Zebrafish
nucleoside phosphate catabolic processGO:19012921100.011
apoptotic processGO:00069151590.011
cell migrationGO:00164772380.011
endoderm formationGO:000170630.011
posttranscriptional regulation of gene expressionGO:00106081450.011
mesenchymal cell differentiationGO:004876210.011
regulation of embryonic developmentGO:0045995680.011
skeletal muscle fiber developmentGO:004874130.011
positive regulation of intracellular signal transductionGO:19025331160.011
male genitalia developmentGO:0030539190.011
antennal joint developmentGO:004809850.011
single organism membrane organizationGO:0044802930.011
cellular response to monosaccharide stimulusGO:007132620.011
regulation of muscle cell differentiationGO:005114780.011
metal ion transportGO:0030001740.011
response to glucoseGO:000974920.011
lipid metabolic processGO:00066291210.011
embryonic pattern specificationGO:00098801740.010
regulation of epidermal cell differentiationGO:004560430.010
anterior malpighian tubule developmentGO:0061327120.010
somatic muscle developmentGO:0007525660.010
wnt signaling pathwayGO:0016055980.010
tube fusionGO:0035146170.010
cellular component assembly involved in morphogenesisGO:00109271510.010
tissue migrationGO:00901301550.010

elB disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
disease of cellular proliferationDOID:1456600.029
nervous system diseaseDOID:86300.019
organ system cancerDOID:005068600.014
cancerDOID:16200.014
cardiovascular system diseaseDOID:128700.014
vascular diseaseDOID:17800.013