Drosophila melanogaster

0 known processes

Tpr2 (Dmel_CG4599)

Tetratricopeptide repeat protein 2

(Aliases: EU3220,CG4599,Dmel\CG4599,BEST:LD24941,dtpr2,dtrpr2,tpr2,dTpr2,Trp2,dTPR2)

Tpr2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense responseGO:00069523000.111
protein modification by small protein conjugation or removalGO:00706471060.107
programmed cell deathGO:00125012570.100
nuclear divisionGO:00002803320.097
regulation of cell cycleGO:00517262910.094
protein transportGO:00150311550.077
phosphorylationGO:00163102940.076
deathGO:00162652840.076
cellular macromolecule localizationGO:00707272200.073
protein modification by small protein removalGO:0070646280.073
transmembrane transportGO:00550851390.072
protein localizationGO:00081042840.072
regulation of intracellular signal transductionGO:19025312360.072
proteolysisGO:00065081920.071
catabolic processGO:00090564090.070
protein modification processGO:00362114380.068
regulation of transportGO:00510491810.067
regulation of cellular protein catabolic processGO:1903362440.064
apoptotic processGO:00069151590.063
cellular catabolic processGO:00442483720.059
response to external biotic stimulusGO:00432072930.057
regulation of localizationGO:00328792750.056
regulation of protein metabolic processGO:00512462560.054
macromolecule catabolic processGO:00090571610.054
cellular macromolecule catabolic processGO:00442651360.053
establishment of localization in cellGO:00516494020.051
organic substance transportGO:00717022570.049
establishment of protein localizationGO:00451841630.049
microtubule organizing center organizationGO:00310231680.048
organic substance catabolic processGO:19015753080.048
multicellular organismal agingGO:00102591400.048
regulation of cell deathGO:00109411730.048
cell deathGO:00082192790.047
protein deubiquitinationGO:0016579170.047
cellular protein modification processGO:00064644380.044
sperm individualizationGO:0007291480.044
intracellular transportGO:00469072280.042
organelle fissionGO:00482853400.042
negative regulation of signalingGO:00230572190.042
mitotic dna integrity checkpointGO:0044774750.042
growthGO:00400073590.039
spermatogenesisGO:00072832000.039
cell divisionGO:00513012480.039
defense response to other organismGO:00985422250.038
regulation of defense responseGO:00313471020.037
nucleocytoplasmic transportGO:0006913720.036
regulation of programmed cell deathGO:00430671520.036
regulation of multi organism processGO:00439001310.036
neurological system processGO:00508773580.035
positive regulation of protein localization to nucleusGO:1900182210.034
regulation of mitotic cell cycleGO:00073461900.034
germarium derived egg chamber formationGO:00072931010.033
single organism nuclear importGO:1902593510.033
regulation of apoptotic processGO:00429811300.033
regulation of meiosisGO:004002030.033
organophosphate metabolic processGO:00196371950.033
protein localization to nucleusGO:0034504550.033
determination of adult lifespanGO:00083401370.032
signal transduction by phosphorylationGO:00230141070.031
negative regulation of cell communicationGO:00106482230.030
chaeta developmentGO:0022416970.030
protein modification by small protein conjugationGO:0032446790.030
positive regulation of signalingGO:00230562430.030
male gamete generationGO:00482322010.030
regulation of transcription from rna polymerase ii promoterGO:00063573780.028
regulation of growthGO:00400082330.028
rna catabolic processGO:0006401370.028
mitochondrion organizationGO:0007005650.028
activation of cysteine type endopeptidase activityGO:0097202170.028
negative regulation of response to external stimulusGO:0032102220.028
mapk cascadeGO:00001651070.027
protein targeting to nucleusGO:0044744510.027
response to other organismGO:00517072930.027
negative regulation of response to stimulusGO:00485852580.027
cellular protein catabolic processGO:0044257830.027
protein ubiquitinationGO:0016567700.026
developmental growthGO:00485892800.026
posttranscriptional regulation of gene expressionGO:00106081450.026
regulation of catabolic processGO:00098941700.026
positive regulation of macromolecule metabolic processGO:00106044050.026
protein importGO:0017038550.026
positive regulation of multicellular organismal processGO:00512401430.026
sleepGO:0030431490.026
positive regulation of cell communicationGO:00106472500.026
positive regulation of nucleic acid templated transcriptionGO:19035082660.025
mesenchymal cell differentiationGO:004876210.025
response to abiotic stimulusGO:00096283410.025
immune system processGO:00023763470.025
positive regulation of response to stimulusGO:00485843230.025
response to bacteriumGO:00096171980.025
regulation of nucleocytoplasmic transportGO:0046822350.024
protein maturationGO:0051604710.024
protein processingGO:0016485680.024
cytokinesisGO:0000910900.024
eye developmentGO:00016543230.024
cellular nitrogen compound catabolic processGO:00442701650.023
mrna catabolic processGO:0006402330.023
modification dependent protein catabolic processGO:0019941780.023
agingGO:00075681430.023
chromosome organizationGO:00512763600.023
organonitrogen compound metabolic processGO:19015643180.023
nucleus organizationGO:0006997450.022
intracellular protein transportGO:00068861040.022
regulation of molecular functionGO:00650092170.022
intracellular signal transductionGO:00355563000.022
regulation of cellular component biogenesisGO:00440872010.022
regulation of protein import into nucleusGO:0042306280.021
regulation of cell divisionGO:0051302720.021
mrna processingGO:00063971040.021
proteolysis involved in cellular protein catabolic processGO:0051603830.021
single organism catabolic processGO:00447122280.021
centrosome organizationGO:00512971630.020
regulation of protein localization to nucleusGO:1900180290.020
nuclear importGO:0051170510.020
synaptic transmissionGO:00072682880.020
positive regulation of signal transductionGO:00099672230.020
positive regulation of protein transportGO:0051222370.020
regulation of developmental growthGO:00486381740.020
response to biotic stimulusGO:00096072940.020
regulation of protein catabolic processGO:0042176550.020
endocytosisGO:00068973100.020
g2 dna damage checkpointGO:0031572690.020
regulation of cellular protein metabolic processGO:00322682430.020
regulation of protein localizationGO:0032880760.019
negative regulation of signal transductionGO:00099682060.019
negative regulation of biosynthetic processGO:00098902770.019
kidney developmentGO:000182230.019
appendage morphogenesisGO:00351073970.019
transcription from rna polymerase ii promoterGO:00063663680.019
protein catabolic processGO:00301631010.019
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.019
defense response to gram negative bacteriumGO:0050829940.018
positive regulation of transcription dna templatedGO:00458932660.018
peripheral nervous system developmentGO:0007422520.018
regulation of cellular catabolic processGO:00313291570.018
organic cyclic compound catabolic processGO:19013611680.018
spermatid differentiationGO:00485151140.018
aromatic compound catabolic processGO:00194391660.018
positive regulation of nucleocytoplasmic transportGO:0046824240.018
single organism biosynthetic processGO:00447112060.018
regulation of notch signaling pathwayGO:00085931000.018
regulation of endopeptidase activityGO:0052548360.018
synapse organizationGO:00508081960.018
small molecule metabolic processGO:00442813050.017
protein targetingGO:0006605640.017
positive regulation of programmed cell deathGO:0043068620.017
nucleotide metabolic processGO:00091171610.017
mitotic cytokinesisGO:0000281500.017
negative regulation of gene expressionGO:00106293870.017
oxoacid metabolic processGO:00434361030.017
hindgut morphogenesisGO:0007442580.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.017
cellular protein localizationGO:00346131600.017
dna metabolic processGO:00062592270.017
regulation of mapk cascadeGO:0043408920.017
negative regulation of cellular protein metabolic processGO:0032269850.017
imaginal disc derived wing morphogenesisGO:00074763370.017
regulation of cellular response to stressGO:0080135890.016
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.016
response to organic substanceGO:00100332840.016
vesicle mediated transportGO:00161923810.016
positive regulation of protein import into nucleusGO:0042307210.016
nucleotide excision repairGO:000628980.016
negative regulation of transcription dna templatedGO:00458922370.016
cell cycle phase transitionGO:00447701400.016
regulation of phosphate metabolic processGO:00192202100.016
regulation of cellular localizationGO:00603411360.016
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.016
regulation of establishment of protein localizationGO:0070201610.015
regulation of intracellular protein transportGO:0033157460.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
female gonad developmentGO:0008585120.015
nucleoside phosphate metabolic processGO:00067531620.015
rna processingGO:00063961470.015
organic acid metabolic processGO:00060821030.015
negative regulation of multicellular organismal processGO:00512411420.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
regulation of response to stressGO:00801342000.014
negative regulation of protein metabolic processGO:0051248850.014
heterocycle catabolic processGO:00467001660.014
positive regulation of gene expressionGO:00106282900.014
positive regulation of mitotic cell cycle phase transitionGO:1901992200.014
regulation of mitotic cell cycle phase transitionGO:19019901300.014
regulation of synapse structure and activityGO:00508031280.014
innate immune responseGO:00450871440.014
ion transportGO:00068111450.014
establishment of protein localization to organelleGO:0072594620.014
autophagyGO:00069141080.013
oocyte differentiationGO:00099941450.013
positive regulation of rna biosynthetic processGO:19026802660.013
segmentationGO:00352822070.013
protein localization to organelleGO:0033365820.013
regulation of cell cycle phase transitionGO:19019871300.013
regulation of phosphorylationGO:00423251470.013
negative regulation of molecular functionGO:0044092510.013
rhythmic behaviorGO:0007622760.013
protein import into nucleusGO:0006606510.013
regulation of protein transportGO:0051223570.013
negative regulation of developmental processGO:00510932010.013
cell cycle checkpointGO:0000075950.013
regulation of nuclear divisionGO:0051783580.013
mitotic spindle organizationGO:00070522200.013
negative regulation of cellular biosynthetic processGO:00313272770.013
eye morphogenesisGO:00485922600.013
organelle localizationGO:00516401480.013
positive regulation of cell deathGO:0010942690.013
nephron developmentGO:007200630.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.013
positive regulation of intracellular protein transportGO:0090316300.013
positive regulation of nitrogen compound metabolic processGO:00511733540.012
protein transmembrane transportGO:007180640.012
negative regulation of nucleic acid templated transcriptionGO:19035072400.012
spindle assemblyGO:0051225800.012
response to oxidative stressGO:0006979860.012
positive regulation of biosynthetic processGO:00098913160.012
defense response to bacteriumGO:00427421780.012
regulation of protein targetingGO:1903533290.012
mitotic cell cycle phase transitionGO:00447721380.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
response to oxygen containing compoundGO:19017002000.012
protein complex biogenesisGO:00702712010.012
dna conformation changeGO:00711031050.012
cell proliferationGO:00082832990.012
sensory perceptionGO:00076001960.012
inorganic ion transmembrane transportGO:0098660730.012
negative regulation of cell deathGO:0060548810.012
positive regulation of cellular biosynthetic processGO:00313283160.012
centrosome duplicationGO:00512981210.011
intracellular protein transmembrane transportGO:006500240.011
spindle organizationGO:00070512530.011
regulation of organelle organizationGO:00330431960.011
positive regulation of ras protein signal transductionGO:0046579430.011
ras protein signal transductionGO:0007265880.011
erk1 and erk2 cascadeGO:0070371390.011
reproductive structure developmentGO:0048608740.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
regulation of erk1 and erk2 cascadeGO:0070372390.011
muscle system processGO:0003012210.011
posttranscriptional gene silencingGO:0016441460.011
rna localizationGO:00064031150.011
protein phosphorylationGO:00064681690.011
organonitrogen compound biosynthetic processGO:19015661170.011
gland developmentGO:00487321910.011
negative regulation of nitrogen compound metabolic processGO:00511722650.011
regulation of phosphorus metabolic processGO:00511742100.011
compound eye morphogenesisGO:00017452490.011
positive regulation of rna metabolic processGO:00512542710.011
small gtpase mediated signal transductionGO:0007264880.011
positive regulation of proteolysisGO:0045862520.011
notch signaling pathwayGO:00072191200.011
inorganic cation transmembrane transportGO:0098662610.011
ion transmembrane transportGO:00342201220.011
regulation of synapse assemblyGO:0051963940.011
mitotic cell cycle checkpointGO:0007093880.011
mitochondrial fissionGO:000026680.011
cytoplasmic transportGO:00164821300.011
positive regulation of growthGO:0045927750.011
ubiquitin homeostasisGO:001099210.011
single organism behaviorGO:00447083910.011
synaptic growth at neuromuscular junctionGO:00511241190.011
mitotic nuclear divisionGO:00070672130.011
cellularizationGO:0007349900.011
development of primary sexual characteristicsGO:0045137500.010
detection of stimulusGO:00516061560.010
response to nutrient levelsGO:00316671140.010
imaginal disc derived appendage morphogenesisGO:00351143950.010
negative regulation of catabolic processGO:0009895360.010
regulation of hemocyte proliferationGO:0035206370.010
negative regulation of cell differentiationGO:00455961430.010
embryonic pattern specificationGO:00098801740.010
purine ribonucleotide metabolic processGO:00091501450.010
positive regulation of erk1 and erk2 cascadeGO:0070374360.010
positive regulation of apoptotic processGO:0043065470.010
positive regulation of cell cycleGO:0045787430.010

Tpr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.030
disease of anatomical entityDOID:700.030
kidney diseaseDOID:55700.030
renal tubular transport diseaseDOID:44700.030
inherited metabolic disorderDOID:65500.014
disease of metabolismDOID:001466700.014
nervous system diseaseDOID:86300.014
musculoskeletal system diseaseDOID:1700.013