Drosophila melanogaster

75 known processes

scf (Dmel_CG9148)

supercoiling factor

(Aliases: SCF,anon-EST:Posey14,CK02682,DCB-45,Dmel\CG9148,CG9148,BEST:CK02682)

scf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular catabolic processGO:00442483720.265
establishment of localization in cellGO:00516494020.249
multi organism behaviorGO:00517051750.237
gland developmentGO:00487321910.160
peptidyl proline hydroxylationGO:001951110.116
intracellular transportGO:00469072280.110
vesicle mediated transportGO:00161923810.100
response to organic substanceGO:00100332840.095
Rat
regionalizationGO:00030024160.092
tube morphogenesisGO:00352391910.090
protein modification processGO:00362114380.089
digestive system developmentGO:00551231490.084
protein localizationGO:00081042840.082
positive regulation of nitrogen compound metabolic processGO:00511733540.082
membrane organizationGO:00610241120.080
catabolic processGO:00090564090.077
protein hydroxylationGO:001812610.075
digestive tract morphogenesisGO:00485461270.074
peptidyl amino acid modificationGO:00181931050.068
regulation of transcription from rna polymerase ii promoterGO:00063573780.067
salivary gland morphogenesisGO:00074351450.066
regulation of multicellular organismal developmentGO:20000264140.066
secondary metabolic processGO:0019748750.064
digestive tract developmentGO:00485651490.062
imaginal disc derived appendage developmentGO:00487373990.058
post embryonic appendage morphogenesisGO:00351203850.055
gland morphogenesisGO:00226121450.053
wing disc morphogenesisGO:00074723440.053
peptidyl proline modificationGO:001820830.052
spermatogenesisGO:00072832000.052
spermatid differentiationGO:00485151140.051
cell migrationGO:00164772380.051
exocrine system developmentGO:00352721620.051
transcription from rna polymerase ii promoterGO:00063663680.050
intracellular signal transductionGO:00355563000.050
regulation of anatomical structure sizeGO:00900661630.049
cell motilityGO:00488702510.049
response to abiotic stimulusGO:00096283410.048
cellular protein modification processGO:00064644380.048
positive regulation of cellular biosynthetic processGO:00313283160.047
single organism behaviorGO:00447083910.046
regulation of anatomical structure morphogenesisGO:00226032420.046
cellular response to chemical stimulusGO:00708871990.045
localization of cellGO:00516742570.044
appendage morphogenesisGO:00351073970.043
imaginal disc derived appendage morphogenesisGO:00351143950.042
endocytosisGO:00068973100.041
negative regulation of nitrogen compound metabolic processGO:00511722650.041
positive regulation of nucleobase containing compound metabolic processGO:00459353320.041
lipid storageGO:0019915380.040
embryonic morphogenesisGO:00485982060.039
regulation of intracellular signal transductionGO:19025312360.038
male gamete generationGO:00482322010.038
positive regulation of rna metabolic processGO:00512542710.037
axon developmentGO:00615642970.037
Rat
phenol containing compound metabolic processGO:0018958570.037
regulation of localizationGO:00328792750.036
central nervous system developmentGO:00074172010.036
positive regulation of rna biosynthetic processGO:19026802660.036
positive regulation of macromolecule biosynthetic processGO:00105572830.035
biological adhesionGO:00226101380.034
nephron developmentGO:007200630.034
positive regulation of biosynthetic processGO:00098913160.033
response to bacteriumGO:00096171980.033
striated muscle cell differentiationGO:0051146900.033
organic substance catabolic processGO:19015753080.033
positive regulation of macromolecule metabolic processGO:00106044050.033
regulation of cell developmentGO:00602842150.033
multi organism reproductive behaviorGO:00447051210.033
growthGO:00400073590.032
muscle organ developmentGO:00075171270.031
salivary gland developmentGO:00074311620.031
larval developmentGO:00021641040.031
cellular amine metabolic processGO:0044106120.031
positive regulation of gene expressionGO:00106282900.030
lateral inhibitionGO:00463312060.030
positive regulation of response to stimulusGO:00485843230.030
response to biotic stimulusGO:00096072940.030
amine metabolic processGO:0009308120.029
negative regulation of macromolecule biosynthetic processGO:00105582700.029
reproductive behaviorGO:00190981220.029
multi multicellular organism processGO:00447061230.029
single organism intracellular transportGO:19025822070.029
cell deathGO:00082192790.028
mating behaviorGO:00076171060.028
cytoplasmic transportGO:00164821300.028
matingGO:00076181200.028
single organism membrane organizationGO:0044802930.028
embryo development ending in birth or egg hatchingGO:00097921520.028
Mouse
anatomical structure homeostasisGO:0060249970.027
kidney developmentGO:000182230.027
phagocytosisGO:00069092150.027
regulation of multivesicular body size involved in endosome transportGO:001079720.027
appendage developmentGO:00487364010.027
tube developmentGO:00352952440.027
programmed cell deathGO:00125012570.026
androgen metabolic processGO:000820910.026
urogenital system developmentGO:0001655720.026
regulation of growthGO:00400082330.026
establishment of protein localizationGO:00451841630.025
immune system processGO:00023763470.025
organic substance transportGO:00717022570.025
regulation of nervous system developmentGO:00519602480.025
negative regulation of nucleobase containing compound metabolic processGO:00459342610.025
response to inorganic substanceGO:0010035440.025
developmental programmed cell deathGO:00106231380.025
cellular ketone metabolic processGO:0042180240.024
body morphogenesisGO:001017120.024
forebrain developmentGO:003090020.024
wing disc pattern formationGO:0035222660.024
gonad developmentGO:0008406500.023
multicellular organismal reproductive behaviorGO:00330571100.023
secretion by cellGO:00329401010.023
deathGO:00162652840.023
compound eye developmentGO:00487493070.023
ras protein signal transductionGO:0007265880.023
cell adhesionGO:00071551360.023
eye morphogenesisGO:00485922600.023
muscle structure developmentGO:00610612240.023
neurological system processGO:00508773580.023
morphogenesis of an epitheliumGO:00020092760.023
camera type eye developmentGO:004301040.022
Mouse
negative regulation of multicellular organismal processGO:00512411420.022
brain developmentGO:00074201200.022
cell cell signaling involved in cell fate commitmentGO:00451682100.022
regulation of molecular functionGO:00650092170.022
Rat
carbohydrate derivative metabolic processGO:19011352170.021
protein transportGO:00150311550.021
cellular protein localizationGO:00346131600.021
response to oxygen containing compoundGO:19017002000.021
response to other organismGO:00517072930.021
segmentationGO:00352822070.021
positive regulation of signalingGO:00230562430.021
immune responseGO:00069552460.021
regulation of protein metabolic processGO:00512462560.021
organic cyclic compound catabolic processGO:19013611680.021
small molecule metabolic processGO:00442813050.021
regulation of response to stressGO:00801342000.021
chemosensory behaviorGO:00076351060.021
negative regulation of signalingGO:00230572190.021
regulation of transportGO:00510491810.020
taxisGO:00423303040.020
negative regulation of cellular metabolic processGO:00313243820.020
regulation of cellular protein metabolic processGO:00322682430.020
regulation of catalytic activityGO:00507901850.020
Rat
oocyte differentiationGO:00099941450.020
chemotaxisGO:00069352490.020
steroid catabolic processGO:000670610.020
carboxylic acid metabolic processGO:0019752920.019
positive regulation of developmental processGO:00510941430.019
alpha amino acid metabolic processGO:1901605200.019
maintenance of cell polarityGO:0030011180.019
regulation of organelle organizationGO:00330431960.019
defense response to bacteriumGO:00427421780.019
defense responseGO:00069523000.019
regulation of multi organism processGO:00439001310.019
compound eye morphogenesisGO:00017452490.019
regulation of cell morphogenesisGO:00226041630.019
organonitrogen compound metabolic processGO:19015643180.019
axis specificationGO:00097981670.019
encapsulation of foreign targetGO:0035010380.019
heterocycle catabolic processGO:00467001660.019
response to lipopolysaccharideGO:003249640.019
ubiquitin dependent protein catabolic processGO:0006511780.018
regulation of cellular component sizeGO:0032535980.018
positive regulation of signal transductionGO:00099672230.018
secretionGO:00469031090.018
regulation of cellular ketone metabolic processGO:001056530.018
meiotic cell cycleGO:00513211710.018
cellular response to organic substanceGO:00713101320.018
locomotory behaviorGO:00076261760.018
regulation of cell deathGO:00109411730.018
tissue morphogenesisGO:00487292970.018
extracellular structure organizationGO:0043062460.018
imaginal disc pattern formationGO:0007447910.018
epithelial cell differentiationGO:00308553220.017
organic acid metabolic processGO:00060821030.017
regulation of small gtpase mediated signal transductionGO:0051056930.017
regulation of phosphorus metabolic processGO:00511742100.017
positive regulation of transcription dna templatedGO:00458932660.017
hormone catabolic processGO:004244730.017
imaginal disc derived wing morphogenesisGO:00074763370.017
small gtpase mediated signal transductionGO:0007264880.017
negative regulation of signal transductionGO:00099682060.017
embryonic pattern specificationGO:00098801740.017
developmental growthGO:00485892800.017
cell proliferationGO:00082832990.017
positive regulation of cell migrationGO:003033520.017
notch signaling pathwayGO:00072191200.017
negative regulation of cell developmentGO:0010721620.017
regulation of mitotic cell cycleGO:00073461900.017
positive regulation of cell communicationGO:00106472500.017
regulation of cellular amine metabolic processGO:003323830.016
protein complex biogenesisGO:00702712010.016
protein secretionGO:0009306450.016
regulation of catabolic processGO:00098941700.016
negative regulation of developmental processGO:00510932010.016
single organism carbohydrate metabolic processGO:0044723720.016
inter male aggressive behaviorGO:0002121600.016
response to organophosphorusGO:004668320.016
ethanolamine containing compound metabolic processGO:004243940.016
positive regulation of cellular component organizationGO:00511301560.016
cellular macromolecule catabolic processGO:00442651360.016
regulation of organ morphogenesisGO:2000027780.016
membrane fusionGO:0061025420.016
positive regulation of cell motilityGO:200014730.016
regulation of cell differentiationGO:00455953020.016
oxoacid metabolic processGO:00434361030.015
anterior posterior pattern specificationGO:00099521360.015
negative regulation of cell communicationGO:00106482230.015
cellular response to oxygen containing compoundGO:1901701790.015
negative regulation of gene expressionGO:00106293870.015
dna metabolic processGO:00062592270.015
negative regulation of rna metabolic processGO:00512532510.015
regulation of programmed cell deathGO:00430671520.015
xenobiotic catabolic processGO:004217810.015
response to ketoneGO:1901654340.015
basement membrane organizationGO:0071711100.015
regulation of epithelial cell proliferationGO:005067840.015
anterior posterior axis specification embryoGO:00085951030.015
regulation of notch signaling pathwayGO:00085931000.015
regulation of ras protein signal transductionGO:0046578930.015
sensory organ morphogenesisGO:00905962600.014
melanization defense responseGO:0035006450.014
leg disc morphogenesisGO:0007478800.014
regulation of cellular localizationGO:00603411360.014
response to organic cyclic compoundGO:0014070890.014
Rat
phosphorylationGO:00163102940.014
developmental maturationGO:00217001720.014
regulation of cell proliferationGO:00421271630.014
cellular macromolecule localizationGO:00707272200.014
regulation of protein secretionGO:0050708130.014
spermatid developmentGO:0007286980.014
oocyte developmentGO:00485991240.014
asymmetric protein localizationGO:0008105330.014
neuromuscular junction developmentGO:00075281490.014
negative regulation of nervous system developmentGO:0051961920.014
positive regulation of multicellular organismal processGO:00512401430.014
homeostatic processGO:00425921990.014
carbohydrate derivative catabolic processGO:19011361180.014
eye developmentGO:00016543230.013
Mouse
response to external biotic stimulusGO:00432072930.013
blastoderm segmentationGO:00073501590.013
negative regulation of response to stimulusGO:00485852580.013
positive regulation of intracellular signal transductionGO:19025331160.013
extracellular matrix organizationGO:0030198320.013
cellular amino acid metabolic processGO:0006520610.013
cellular homeostasisGO:0019725800.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
cellular protein catabolic processGO:0044257830.013
positive regulation of phosphorus metabolic processGO:00105621390.013
cell maturationGO:00484691440.013
cell cycle arrestGO:000705040.013
positive regulation of molecular functionGO:00440931360.013
ion transportGO:00068111450.013
macromolecule catabolic processGO:00090571610.013
tripartite regional subdivisionGO:00073511030.013
response to oxidative stressGO:0006979860.013
organelle fissionGO:00482853400.013
mesenchymal cell differentiationGO:004876210.013
negative regulation of rna biosynthetic processGO:19026792400.013
apoptotic processGO:00069151590.013
telencephalon developmentGO:002153720.013
wing disc dorsal ventral pattern formationGO:0048190470.012
pigment metabolic processGO:0042440840.012
negative regulation of biosynthetic processGO:00098902770.012
regulation of phosphate metabolic processGO:00192202100.012
axon guidanceGO:00074112330.012
regulation of embryonic developmentGO:0045995680.012
salivary gland histolysisGO:0035070880.012
negative regulation of cell cycleGO:00457861160.012
head developmentGO:00603221350.012
axonogenesisGO:00074092900.012
regulation of cellular amino acid metabolic processGO:000652100.012
posttranscriptional regulation of gene expressionGO:00106081450.012
nephron morphogenesisGO:007202830.012
organonitrogen compound biosynthetic processGO:19015661170.012
embryonic development via the syncytial blastodermGO:00017001480.012
innate immune responseGO:00450871440.012
male mating behaviorGO:0060179700.012
negative regulation of cell differentiationGO:00455961430.012
neuron projection guidanceGO:00974852410.012
protein n linked glycosylationGO:000648790.012
endomembrane system organizationGO:00102561190.012
Fly
regulation of cell shapeGO:00083601130.012
respiratory system developmentGO:00605412130.012
cellular response to dna damage stimulusGO:00069742230.012
jak stat cascadeGO:0007259490.012
defense response to other organismGO:00985422250.012
maintenance of locationGO:0051235730.011
dendrite morphogenesisGO:00488131990.011
substrate adhesion dependent cell spreadingGO:003444620.011
single organism cellular localizationGO:19025801800.011
negative regulation of cell cycle phase transitionGO:19019881030.011
dorsal ventral pattern formation imaginal discGO:0007450510.011
negative regulation of cellular protein metabolic processGO:0032269850.011
regulation of phosphorylationGO:00423251470.011
positive regulation of cellular amine metabolic processGO:003324000.011
aggressive behaviorGO:0002118630.011
regulation of cellular response to stressGO:0080135890.011
hindgut morphogenesisGO:0007442580.011
modification dependent macromolecule catabolic processGO:0043632790.011
dendrite developmentGO:00163582040.011
modification dependent protein catabolic processGO:0019941780.011
oocyte constructionGO:00073081120.011
courtship behaviorGO:0007619680.011
macromolecular complex assemblyGO:00650032560.011
embryonic axis specificationGO:00005781070.011
cell growthGO:00160491080.011
positive regulation of response to external stimulusGO:0032103440.011
mitotic cell cycle phase transitionGO:00447721380.011
positive regulation of catalytic activityGO:00430851180.011
cellular nitrogen compound catabolic processGO:00442701650.011
protein localization to organelleGO:0033365820.011
negative regulation of cellular biosynthetic processGO:00313272770.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
organic hydroxy compound metabolic processGO:1901615830.011
regulation of hydrolase activityGO:0051336970.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
tissue deathGO:00162711020.011
protein phosphorylationGO:00064681690.011
single organism catabolic processGO:00447122280.011
lymph gland developmentGO:0048542280.011
regulation of response to external stimulusGO:00321011150.011
positive regulation of phosphate metabolic processGO:00459371390.010
response to endogenous stimulusGO:00097191190.010
dorsal ventral pattern formationGO:00099531330.010
reproductive system developmentGO:0061458740.010
lipid metabolic processGO:00066291210.010
response to extracellular stimulusGO:00099911160.010
regulation of cellular component biogenesisGO:00440872010.010
protein complex assemblyGO:00064612000.010
midgut developmentGO:0007494230.010
mesenchymal cell developmentGO:001403110.010
proteasomal protein catabolic processGO:0010498590.010
autophagic cell deathGO:0048102830.010
columnar cuboidal epithelial cell differentiationGO:00020652560.010
regulation of cellular catabolic processGO:00313291570.010
positive regulation of growthGO:0045927750.010
response to calcium ionGO:005159210.010
autophagyGO:00069141080.010
nucleoside phosphate catabolic processGO:19012921100.010
retina development in camera type eyeGO:006004140.010
regulation of mitotic cell cycle phase transitionGO:19019901300.010
establishment of organelle localizationGO:00516561220.010
nuclear divisionGO:00002803320.010
immune effector processGO:0002252980.010
gastrulationGO:0007369700.010
regulation of cell cycleGO:00517262910.010
synaptic transmissionGO:00072682880.010

scf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
cardiovascular system diseaseDOID:128700.017
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.015
musculoskeletal system diseaseDOID:1700.013
organ system cancerDOID:005068600.012