Drosophila melanogaster

125 known processes

Rgl (Dmel_CG8865)

Ral guanine nucleotide exchange factor

(Aliases: Dmel\CG8865,RalGDS,CG8865,DRgl,rgl,dRGL)

Rgl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell proliferationGO:00082832990.517
response to abiotic stimulusGO:00096283410.431
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.416
actin cytoskeleton organizationGO:00300362060.376
catabolic processGO:00090564090.358
immune response regulating signaling pathwayGO:000276420.325
positive regulation of macromolecule metabolic processGO:00106044050.275
organic substance catabolic processGO:19015753080.264
cellular catabolic processGO:00442483720.237
single organism behaviorGO:00447083910.235
regulation of intracellular signal transductionGO:19025312360.218
long term memoryGO:0007616620.200
positive regulation of nitrogen compound metabolic processGO:00511733540.200
regulation of notch signaling pathwayGO:00085931000.194
locomotory behaviorGO:00076261760.178
organic cyclic compound catabolic processGO:19013611680.170
regulation of transcription from rna polymerase ii promoterGO:00063573780.161
positive regulation of rna metabolic processGO:00512542710.161
cellular response to organic substanceGO:00713101320.155
wing disc morphogenesisGO:00074723440.146
intracellular signal transductionGO:00355563000.143
negative regulation of response to stimulusGO:00485852580.142
cognitionGO:00508901410.141
chromosome segregationGO:00070591570.132
taxisGO:00423303040.131
negative regulation of signal transductionGO:00099682060.130
imaginal disc derived appendage morphogenesisGO:00351143950.130
regionalizationGO:00030024160.128
stem cell differentiationGO:00488631170.127
positive regulation of response to stimulusGO:00485843230.123
organonitrogen compound metabolic processGO:19015643180.117
establishment of localization in cellGO:00516494020.117
urogenital system developmentGO:0001655720.116
chemosensory behaviorGO:00076351060.114
transcription from rna polymerase ii promoterGO:00063663680.114
positive regulation of biosynthetic processGO:00098913160.111
positive regulation of nucleobase containing compound metabolic processGO:00459353320.107
regulation of molecular functionGO:00650092170.107
learning or memoryGO:00076111410.106
homeostatic processGO:00425921990.105
positive regulation of rna biosynthetic processGO:19026802660.104
actin filament organizationGO:00070151260.103
establishment or maintenance of cell polarityGO:00071631670.102
protein localizationGO:00081042840.101
small gtpase mediated signal transductionGO:0007264880.100
regulation of multicellular organismal developmentGO:20000264140.098
Worm
regulation of phosphorus metabolic processGO:00511742100.098
imaginal disc derived appendage developmentGO:00487373990.097
nucleobase containing compound catabolic processGO:00346551650.096
imaginal disc derived wing morphogenesisGO:00074763370.096
regulation of cellular catabolic processGO:00313291570.094
negative regulation of rna metabolic processGO:00512532510.093
forebrain developmentGO:003090020.090
axonogenesisGO:00074092900.089
negative regulation of developmental processGO:00510932010.087
negative regulation of signalingGO:00230572190.086
dorsal closureGO:0007391790.084
intracellular transportGO:00469072280.084
embryo development ending in birth or egg hatchingGO:00097921520.083
negative regulation of cellular metabolic processGO:00313243820.083
immune response activating signal transductionGO:000275720.082
epithelial cell differentiationGO:00308553220.080
embryonic development via the syncytial blastodermGO:00017001480.080
adult behaviorGO:00305341370.080
signal transduction by phosphorylationGO:00230141070.079
positive regulation of nucleic acid templated transcriptionGO:19035082660.078
heterocycle catabolic processGO:00467001660.078
regulation of neurogenesisGO:00507671580.076
cellular protein modification processGO:00064644380.076
protein phosphorylationGO:00064681690.075
olfactory behaviorGO:0042048970.074
purine ribonucleoside catabolic processGO:00461301120.073
carbohydrate derivative metabolic processGO:19011352170.072
positive regulation of gene expressionGO:00106282900.071
appendage developmentGO:00487364010.070
negative regulation of nucleobase containing compound metabolic processGO:00459342610.069
purine ribonucleoside triphosphate catabolic processGO:00092071080.068
positive regulation of transportGO:0051050920.068
memoryGO:0007613940.066
meiotic chromosome segregationGO:0045132590.064
regulation of immune effector processGO:0002697520.063
negative regulation of multicellular organismal processGO:00512411420.062
positive regulation of signalingGO:00230562430.062
cellular amino acid metabolic processGO:0006520610.061
positive regulation of macromolecule biosynthetic processGO:00105572830.058
cellular response to chemical stimulusGO:00708871990.058
positive regulation of transcription dna templatedGO:00458932660.057
positive regulation of molecular functionGO:00440931360.057
immune system processGO:00023763470.057
positive regulation of catabolic processGO:00098961050.057
regulation of cell differentiationGO:00455953020.055
posttranscriptional gene silencing by rnaGO:0035194450.055
mapk cascadeGO:00001651070.054
endocytosisGO:00068973100.053
regulation of cytoskeleton organizationGO:0051493890.052
morphogenesis of embryonic epitheliumGO:0016331940.051
positive regulation of developmental processGO:00510941430.050
Worm
renal system developmentGO:0072001720.050
regulation of response to stressGO:00801342000.049
ras protein signal transductionGO:0007265880.049
chaeta developmentGO:0022416970.049
response to organic substanceGO:00100332840.048
actin filament based processGO:00300292200.048
ribonucleoside metabolic processGO:00091191270.048
aromatic compound catabolic processGO:00194391660.048
positive regulation of catalytic activityGO:00430851180.048
response to external biotic stimulusGO:00432072930.047
positive regulation of signal transductionGO:00099672230.047
negative regulation of cellular biosynthetic processGO:00313272770.046
vesicle mediated transportGO:00161923810.046
post embryonic appendage morphogenesisGO:00351203850.046
posttranscriptional gene silencingGO:0016441460.045
regulation of protein metabolic processGO:00512462560.045
protein modification processGO:00362114380.044
positive regulation of cellular biosynthetic processGO:00313283160.044
regulation of ras protein signal transductionGO:0046578930.044
deathGO:00162652840.043
nucleoside triphosphate metabolic processGO:00091411200.043
cortical actin cytoskeleton organizationGO:0030866240.043
gtp metabolic processGO:0046039720.043
posttranscriptional regulation of gene expressionGO:00106081450.042
protein catabolic processGO:00301631010.041
programmed cell deathGO:00125012570.041
notch signaling pathwayGO:00072191200.041
mitotic spindle organizationGO:00070522200.041
negative regulation of gene expressionGO:00106293870.041
appendage morphogenesisGO:00351073970.040
dendrite developmentGO:00163582040.040
protein transportGO:00150311550.040
regulation of mapk cascadeGO:0043408920.040
axon developmentGO:00615642970.039
macromolecule catabolic processGO:00090571610.039
neural precursor cell proliferationGO:0061351750.038
enzyme linked receptor protein signaling pathwayGO:00071671790.037
Worm
phagocytosisGO:00069092150.037
purine nucleoside metabolic processGO:00422781270.037
regulation of cell projection organizationGO:0031344920.037
regulation of protein modification processGO:00313991120.037
positive regulation of multicellular organismal processGO:00512401430.037
Worm
morphogenesis of follicular epitheliumGO:0016333360.036
regulation of catalytic activityGO:00507901850.036
meiotic cell cycle processGO:19030461320.035
positive regulation of phosphorus metabolic processGO:00105621390.035
r7 cell differentiationGO:0045466430.035
positive regulation of cell developmentGO:0010720610.035
negative regulation of nitrogen compound metabolic processGO:00511722650.035
regulation of localizationGO:00328792750.034
wnt signaling pathwayGO:0016055980.034
positive regulation of phosphate metabolic processGO:00459371390.034
glycosyl compound catabolic processGO:19016581120.033
negative regulation of cell communicationGO:00106482230.033
regulation of cell developmentGO:00602842150.032
segmentationGO:00352822070.031
cell deathGO:00082192790.031
negative regulation of erk1 and erk2 cascadeGO:007037330.031
response to nutrient levelsGO:00316671140.030
positive regulation of protein metabolic processGO:00512471280.030
chemotaxisGO:00069352490.029
growthGO:00400073590.029
immune responseGO:00069552460.029
asymmetric neuroblast divisionGO:0055059330.029
stem cell proliferationGO:0072089880.029
small molecule metabolic processGO:00442813050.029
cellular component disassemblyGO:0022411460.028
larval developmentGO:00021641040.027
Worm
ameboidal type cell migrationGO:00016671510.027
cellular nitrogen compound catabolic processGO:00442701650.027
head developmentGO:00603221350.027
regulation of synaptic transmissionGO:0050804690.027
regulation of phosphate metabolic processGO:00192202100.027
neuroblast proliferationGO:0007405740.027
regulation of nervous system developmentGO:00519602480.026
embryonic pattern specificationGO:00098801740.026
cell migrationGO:00164772380.026
regulation of immune responseGO:00507761180.026
guanosine containing compound catabolic processGO:1901069740.025
nucleotide metabolic processGO:00091171610.025
antimicrobial humoral responseGO:0019730990.025
positive regulation of immune responseGO:0050778630.025
nucleoside catabolic processGO:00091641120.024
organelle localizationGO:00516401480.024
nucleoside phosphate metabolic processGO:00067531620.024
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015340.024
positive regulation of cell communicationGO:00106472500.024
single organism catabolic processGO:00447122280.024
negative regulation of rna biosynthetic processGO:19026792400.024
epithelium migrationGO:00901321480.023
purine nucleoside triphosphate metabolic processGO:00091441190.023
tissue migrationGO:00901301550.023
response to virusGO:0009615280.023
defense response to other organismGO:00985422250.023
immune system developmentGO:0002520570.023
cell divisionGO:00513012480.023
ensheathment of neuronsGO:0007272100.023
organic acid metabolic processGO:00060821030.023
apoptotic signaling pathwayGO:0097190270.023
developmental growthGO:00485892800.022
negative regulation of transcription dna templatedGO:00458922370.022
negative regulation of neurogenesisGO:0050768530.021
purine containing compound catabolic processGO:00725231120.021
cellular macromolecule catabolic processGO:00442651360.021
regulation of cell proliferationGO:00421271630.021
establishment of protein localizationGO:00451841630.021
biological adhesionGO:00226101380.021
secretionGO:00469031090.020
nucleobase containing small molecule metabolic processGO:00550861740.020
compound eye morphogenesisGO:00017452490.020
response to other organismGO:00517072930.020
purine ribonucleoside triphosphate metabolic processGO:00092051190.020
regulation of phosphorylationGO:00423251470.020
negative regulation of intracellular signal transductionGO:1902532570.020
cuticle developmentGO:0042335860.020
proteolysisGO:00065081920.020
imaginal disc derived wing vein morphogenesisGO:0008586440.019
cell adhesionGO:00071551360.019
regulation of purine nucleotide catabolic processGO:0033121480.019
single organism carbohydrate metabolic processGO:0044723720.019
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.019
oxoacid metabolic processGO:00434361030.019
ribonucleoside catabolic processGO:00424541120.019
regulation of nucleotide metabolic processGO:0006140620.019
ribonucleoside triphosphate metabolic processGO:00091991190.019
body morphogenesisGO:001017120.019
regulation of mrna processingGO:0050684710.019
cellular protein localizationGO:00346131600.019
maintenance of locationGO:0051235730.018
regulation of organelle organizationGO:00330431960.018
negative regulation of cell differentiationGO:00455961430.018
rhythmic behaviorGO:0007622760.018
neuronal stem cell divisionGO:0036445350.018
positive regulation of hydrolase activityGO:0051345780.018
gene silencing by rnaGO:0031047570.018
rna catabolic processGO:0006401370.018
adult locomotory behaviorGO:0008344760.018
negative regulation of biosynthetic processGO:00098902770.018
organophosphate metabolic processGO:00196371950.018
limb developmentGO:006017310.018
dorsal ventral pattern formationGO:00099531330.018
regulation of gtpase activityGO:0043087440.018
cytoplasmic transportGO:00164821300.018
organonitrogen compound catabolic processGO:19015651280.017
purine nucleotide metabolic processGO:00061631460.017
regulation of cellular protein metabolic processGO:00322682430.017
sensory organ morphogenesisGO:00905962600.017
mesenchymal cell differentiationGO:004876210.017
cell motilityGO:00488702510.017
secretion by cellGO:00329401010.017
phosphorylationGO:00163102940.017
carboxylic acid metabolic processGO:0019752920.017
cortical cytoskeleton organizationGO:0030865290.017
stem cell divisionGO:0017145690.017
chromatin remodelingGO:0006338720.016
organic substance transportGO:00717022570.016
cellular response to dna damage stimulusGO:00069742230.016
negative regulation of cell proliferationGO:0008285690.016
regulation of jnk cascadeGO:0046328400.016
regulation of immune system processGO:00026821760.016
positive regulation of neurogenesisGO:0050769410.016
cellular macromolecule localizationGO:00707272200.016
compound eye photoreceptor cell differentiationGO:00017511400.016
establishment of spindle localizationGO:0051293220.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.016
regulation of cellular ketone metabolic processGO:001056530.015
regulation of membrane depolarizationGO:000325410.015
regulation of multi organism processGO:00439001310.015
protein localization to organelleGO:0033365820.015
positive regulation of nervous system developmentGO:0051962690.015
response to endogenous stimulusGO:00097191190.015
spindle organizationGO:00070512530.015
regulation of vesicle mediated transportGO:0060627590.015
protein targetingGO:0006605640.015
regulation of cellular response to stressGO:0080135890.015
positive regulation of cellular component organizationGO:00511301560.015
regulation of nucleotide catabolic processGO:0030811480.015
muscle structure developmentGO:00610612240.015
mrna splicing via spliceosomeGO:0000398730.014
peripheral nervous system developmentGO:0007422520.014
cellular response to endogenous stimulusGO:0071495800.014
synaptic transmissionGO:00072682880.014
morphogenesis of an epitheliumGO:00020092760.014
single organism cellular localizationGO:19025801800.014
cytoplasmic transport nurse cell to oocyteGO:0007303120.014
response to oxygen containing compoundGO:19017002000.014
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.014
somatic stem cell divisionGO:0048103370.014
stress activated protein kinase signaling cascadeGO:0031098550.014
response to radiationGO:00093141550.014
neuroblast divisionGO:0055057350.014
nucleotide catabolic processGO:00091661090.014
negative regulation of protein metabolic processGO:0051248850.014
regulation of stress activated mapk cascadeGO:0032872410.014
regulation of lipid transportGO:003236830.014
positive regulation of cell migrationGO:003033520.014
blastoderm segmentationGO:00073501590.014
negative regulation of epithelial cell migrationGO:001063310.014
cholesterol transportGO:003030120.014
reproductive system developmentGO:0061458740.014
morphogenesis of a polarized epitheliumGO:0001738930.014
epithelial cell migrationGO:00106311480.014
mrna processingGO:00063971040.014
central nervous system developmentGO:00074172010.013
organophosphate catabolic processGO:00464341120.013
carbohydrate metabolic processGO:0005975820.013
ribose phosphate metabolic processGO:00196931450.013
amine metabolic processGO:0009308120.013
regulation of small gtpase mediated signal transductionGO:0051056930.013
purine ribonucleotide metabolic processGO:00091501450.013
cellular component assembly involved in morphogenesisGO:00109271510.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
positive regulation of nucleoside metabolic processGO:0045979470.013
imaginal disc pattern formationGO:0007447910.013
regulation of hydrolase activityGO:0051336970.013
cell fate determinationGO:0001709910.013
purine nucleotide catabolic processGO:00061951090.013
dendrite morphogenesisGO:00488131990.013
male meiosis chromosome segregationGO:0007060100.012
protein complex assemblyGO:00064612000.012
cell growthGO:00160491080.012
epithelial cell developmentGO:00020642740.012
regulation of cellular amine metabolic processGO:003323830.012
regulation of cellular amino acid metabolic processGO:000652100.012
positive regulation of programmed cell deathGO:0043068620.012
positive regulation of cell deathGO:0010942690.012
axon guidanceGO:00074112330.012
positive regulation of apoptotic processGO:0043065470.012
protein complex disassemblyGO:0043241360.012
immune effector processGO:0002252980.012
open tracheal system developmentGO:00074242040.012
single organismal cell cell adhesionGO:0016337450.012
limb morphogenesisGO:003510810.012
regulation of erbb signaling pathwayGO:1901184420.012
ncrna metabolic processGO:0034660430.012
mitotic sister chromatid segregationGO:0000070870.012
regulation of gtp catabolic processGO:0033124440.012
positive regulation of protein kinase activityGO:0045860250.012
response to biotic stimulusGO:00096072940.012
regulation of purine nucleotide metabolic processGO:1900542620.012
positive regulation of gtpase activityGO:0043547430.012
nephrocyte differentiationGO:0061319120.012
instar larval developmentGO:0002168550.012
stem cell developmentGO:0048864790.011
positive regulation of immune system processGO:0002684680.011
innate immune response activating signal transductionGO:000275820.011
rna processingGO:00063961470.011
rna splicing via transesterification reactionsGO:0000375730.011
regulation of anatomical structure sizeGO:00900661630.011
imaginal disc derived wing vein specificationGO:0007474480.011
cell cell signaling involved in cell fate commitmentGO:00451682100.011
regulation of cell shapeGO:00083601130.011
regulation of actin filament based processGO:0032970420.011
positive regulation of mrna 3 end processingGO:003144240.011
regulation of stress activated protein kinase signaling cascadeGO:0070302420.011
inter male aggressive behaviorGO:0002121600.011
sex differentiationGO:0007548810.011
regulation of mrna metabolic processGO:1903311720.011
regulation of catabolic processGO:00098941700.011
chitin based cuticle developmentGO:0040003490.010
cellular amine metabolic processGO:0044106120.010
mesenchymal cell developmentGO:001403110.010
head involutionGO:0008258350.010
purine containing compound metabolic processGO:00725211550.010
regulation of membrane potentialGO:0042391350.010
telencephalon developmentGO:002153720.010
tube morphogenesisGO:00352391910.010

Rgl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.020
disease of cellular proliferationDOID:1456600.020
disease of anatomical entityDOID:700.019