Drosophila melanogaster

76 known processes

EndoG (Dmel_CG8862)

Endonuclease G

(Aliases: CG8862,Dmel\CG8862)

EndoG biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spermatogenesisGO:00072832000.517
male gamete generationGO:00482322010.456
autophagyGO:00069141080.222
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.203
establishment of localization in cellGO:00516494020.185
positive regulation of macromolecule metabolic processGO:00106044050.173
cell divisionGO:00513012480.161
establishment of protein localizationGO:00451841630.143
positive regulation of cysteine type endopeptidase activityGO:2001056240.137
protein localizationGO:00081042840.126
regulation of protein metabolic processGO:00512462560.125
spermatid differentiationGO:00485151140.122
transcription from rna polymerase ii promoterGO:00063663680.113
central nervous system developmentGO:00074172010.110
response to abiotic stimulusGO:00096283410.110
regulation of cellular protein metabolic processGO:00322682430.105
cellular protein localizationGO:00346131600.104
protein ubiquitinationGO:0016567700.094
single organism cellular localizationGO:19025801800.092
positive regulation of biosynthetic processGO:00098913160.090
regulation of transcription from rna polymerase ii promoterGO:00063573780.085
response to oxidative stressGO:0006979860.085
cellular macromolecule localizationGO:00707272200.082
protein modification by small protein conjugation or removalGO:00706471060.079
establishment of protein localization to organelleGO:0072594620.079
protein transportGO:00150311550.079
posttranscriptional regulation of gene expressionGO:00106081450.079
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.077
apoptotic processGO:00069151590.076
positive regulation of protein metabolic processGO:00512471280.075
organelle fusionGO:0048284460.071
deathGO:00162652840.071
organic substance transportGO:00717022570.069
phosphorylationGO:00163102940.068
growthGO:00400073590.067
regulation of cysteine type endopeptidase activityGO:2000116270.067
spermatocyte divisionGO:0048137130.067
enzyme linked receptor protein signaling pathwayGO:00071671790.067
regulation of cellular catabolic processGO:00313291570.067
regulation of endopeptidase activityGO:0052548360.067
protein modification processGO:00362114380.066
developmental programmed cell deathGO:00106231380.063
multicellular organismal agingGO:00102591400.063
positive regulation of nitrogen compound metabolic processGO:00511733540.063
negative regulation of nitrogen compound metabolic processGO:00511722650.063
positive regulation of response to stimulusGO:00485843230.062
positive regulation of cellular protein metabolic processGO:00322701180.062
positive regulation of signalingGO:00230562430.061
positive regulation of cell communicationGO:00106472500.060
brain developmentGO:00074201200.060
positive regulation of nucleic acid templated transcriptionGO:19035082660.060
positive regulation of molecular functionGO:00440931360.059
cellular protein modification processGO:00064644380.058
protein localization to organelleGO:0033365820.058
proteolysisGO:00065081920.057
positive regulation of hydrolase activityGO:0051345780.056
programmed cell deathGO:00125012570.056
cellular response to starvationGO:0009267610.056
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.056
muscle structure developmentGO:00610612240.055
larval developmentGO:00021641040.055
regulation of transportGO:00510491810.055
negative regulation of nucleobase containing compound metabolic processGO:00459342610.053
regulation of autophagyGO:0010506620.053
cellular response to nutrient levelsGO:0031669620.053
regulation of molecular functionGO:00650092170.052
catabolic processGO:00090564090.052
cell deathGO:00082192790.052
organelle fissionGO:00482853400.052
cell growthGO:00160491080.049
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.049
response to starvationGO:0042594970.049
embryo development ending in birth or egg hatchingGO:00097921520.049
protein modification by small protein conjugationGO:0032446790.049
columnar cuboidal epithelial cell differentiationGO:00020652560.048
negative regulation of signal transductionGO:00099682060.048
regulation of organelle organizationGO:00330431960.048
regulation of catabolic processGO:00098941700.047
anatomical structure homeostasisGO:0060249970.047
cellular response to heatGO:0034605240.046
positive regulation of nucleobase containing compound metabolic processGO:00459353320.046
intracellular signal transductionGO:00355563000.044
protein importGO:0017038550.044
axon developmentGO:00615642970.044
organic substance catabolic processGO:19015753080.044
regulation of response to stressGO:00801342000.044
positive regulation of signal transductionGO:00099672230.043
positive regulation of transcription dna templatedGO:00458932660.043
immune responseGO:00069552460.043
positive regulation of endopeptidase activityGO:0010950260.042
immune system processGO:00023763470.042
chromatin modificationGO:00165681470.042
negative regulation of cell cycleGO:00457861160.041
regulation of apoptotic processGO:00429811300.040
regulation of cellular response to stressGO:0080135890.040
secretion by cellGO:00329401010.040
protein localization to peroxisomeGO:007266220.040
cell maturationGO:00484691440.040
positive regulation of rna biosynthetic processGO:19026802660.039
positive regulation of rna metabolic processGO:00512542710.039
positive regulation of cellular biosynthetic processGO:00313283160.039
negative regulation of macromolecule biosynthetic processGO:00105582700.039
regionalizationGO:00030024160.039
negative regulation of response to stimulusGO:00485852580.038
single organism catabolic processGO:00447122280.038
spermatid developmentGO:0007286980.038
regulation of catalytic activityGO:00507901850.038
positive regulation of cell deathGO:0010942690.037
intracellular transportGO:00469072280.037
regulation of multi organism processGO:00439001310.036
regulation of localizationGO:00328792750.036
negative regulation of rna metabolic processGO:00512532510.036
negative regulation of mitotic cell cycleGO:00459301090.036
regulation of cell cycleGO:00517262910.036
axonogenesisGO:00074092900.035
endocytosisGO:00068973100.035
positive regulation of cell developmentGO:0010720610.034
regulation of phosphate metabolic processGO:00192202100.034
regulation of programmed cell deathGO:00430671520.034
defense response to other organismGO:00985422250.033
negative regulation of signalingGO:00230572190.033
positive regulation of catalytic activityGO:00430851180.033
negative regulation of biosynthetic processGO:00098902770.033
vesicle mediated transportGO:00161923810.032
regulation of response to external stimulusGO:00321011150.032
negative regulation of nucleic acid templated transcriptionGO:19035072400.032
response to other organismGO:00517072930.032
cellular catabolic processGO:00442483720.032
cellular response to organic substanceGO:00713101320.032
single organism intracellular transportGO:19025822070.032
regulation of hydrolase activityGO:0051336970.031
developmental maturationGO:00217001720.031
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.031
positive regulation of peptidase activityGO:0010952290.031
negative regulation of cell cycle processGO:00109481090.031
secretionGO:00469031090.031
regulation of phosphorylationGO:00423251470.030
cellular amino acid metabolic processGO:0006520610.030
cellular response to extracellular stimulusGO:0031668640.030
single organism membrane fusionGO:0044801420.030
mitotic cell cycle checkpointGO:0007093880.030
regulation of intracellular signal transductionGO:19025312360.030
salivary gland morphogenesisGO:00074351450.030
tissue deathGO:00162711020.030
macroautophagyGO:0016236420.029
innate immune responseGO:00450871440.029
gland morphogenesisGO:00226121450.029
positive regulation of gene expressionGO:00106282900.029
germ line stem cell maintenanceGO:0030718500.029
cell cycle checkpointGO:0000075950.028
zymogen activationGO:0031638200.028
response to nutrient levelsGO:00316671140.028
extrinsic apoptotic signaling pathwayGO:009719110.028
negative regulation of gene expressionGO:00106293870.028
ovarian follicle cell developmentGO:00307072480.028
response to external biotic stimulusGO:00432072930.028
positive regulation of phosphate metabolic processGO:00459371390.027
segmentationGO:00352822070.027
response to bacteriumGO:00096171980.027
defense responseGO:00069523000.027
tripartite regional subdivisionGO:00073511030.027
protein maturationGO:0051604710.026
histolysisGO:00075591020.026
organonitrogen compound metabolic processGO:19015643180.026
mitotic dna damage checkpointGO:0044773740.026
response to organic substanceGO:00100332840.026
exocrine system developmentGO:00352721620.026
negative regulation of cell communicationGO:00106482230.025
peroxisome organizationGO:0007031140.025
protein secretionGO:0009306450.025
positive regulation of transportGO:0051050920.025
regulation of establishment of protein localizationGO:0070201610.025
negative regulation of rna biosynthetic processGO:19026792400.024
tissue morphogenesisGO:00487292970.024
compound eye developmentGO:00487493070.024
intracellular protein transportGO:00068861040.024
regulation of phosphorus metabolic processGO:00511742100.024
immune effector processGO:0002252980.024
regulation of macroautophagyGO:0016241150.024
regulation of protein transportGO:0051223570.024
cellular response to external stimulusGO:0071496660.024
negative regulation of cell cycle phase transitionGO:19019881030.024
cellular response to dna damage stimulusGO:00069742230.024
activation of cysteine type endopeptidase activityGO:0097202170.024
synaptic transmissionGO:00072682880.023
positive regulation of macromolecule biosynthetic processGO:00105572830.023
negative regulation of apoptotic processGO:0043066630.023
cytoplasmic transportGO:00164821300.023
synapse organizationGO:00508081960.022
regulation of epithelial cell proliferationGO:005067840.022
response to radiationGO:00093141550.022
positive regulation of response to external stimulusGO:0032103440.022
epithelial cell developmentGO:00020642740.022
response to biotic stimulusGO:00096072940.022
protein phosphorylationGO:00064681690.022
response to oxygen containing compoundGO:19017002000.022
head developmentGO:00603221350.022
respiratory system developmentGO:00605412130.022
mitotic dna integrity checkpointGO:0044774750.021
response to lipopolysaccharideGO:003249640.021
negative regulation of cellular biosynthetic processGO:00313272770.021
protein import into peroxisome matrixGO:001655820.021
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.021
positive regulation of cell motilityGO:200014730.021
negative regulation of developmental processGO:00510932010.021
mapk cascadeGO:00001651070.021
dna recombinationGO:0006310320.021
axon guidanceGO:00074112330.021
regulation of response to biotic stimulusGO:0002831630.020
macromolecule catabolic processGO:00090571610.020
regulation of cellular localizationGO:00603411360.020
cell cycle phase transitionGO:00447701400.020
cell proliferationGO:00082832990.020
regulation of mitotic cell cycleGO:00073461900.019
regulation of protein modification processGO:00313991120.019
endomembrane system organizationGO:00102561190.019
cellular response to chemical stimulusGO:00708871990.019
blastoderm segmentationGO:00073501590.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of defense responseGO:00313471020.019
positive regulation of developmental processGO:00510941430.019
protein processingGO:0016485680.019
regulation of notch signaling pathwayGO:00085931000.019
apoptotic process involved in developmentGO:1902742200.019
small molecule metabolic processGO:00442813050.019
positive regulation of apoptotic processGO:0043065470.019
regulation of immune responseGO:00507761180.019
establishment of protein localization to peroxisomeGO:007266320.018
mitotic cell cycle phase transitionGO:00447721380.018
apoptotic signaling pathwayGO:0097190270.018
single organism nuclear importGO:1902593510.018
epithelial cell differentiationGO:00308553220.018
nuclear importGO:0051170510.018
camera type eye developmentGO:004301040.018
photoreceptor cell differentiationGO:00465301700.018
anterior posterior pattern specificationGO:00099521360.018
phagocytosisGO:00069092150.018
transmembrane transportGO:00550851390.018
positive regulation of intracellular signal transductionGO:19025331160.018
regulation of cytoplasmic transportGO:1903649470.018
positive regulation of phosphorus metabolic processGO:00105621390.018
regulation of peptidase activityGO:0052547390.018
regulation of immune system processGO:00026821760.017
defense response to bacteriumGO:00427421780.017
response to extracellular stimulusGO:00099911160.017
gland developmentGO:00487321910.017
regulation of proteolysisGO:0030162870.017
immune response activating signal transductionGO:000275720.017
taxisGO:00423303040.017
protein targeting to peroxisomeGO:000662520.017
oocyte anterior posterior axis specificationGO:0007314720.017
regulation of protein localizationGO:0032880760.017
wnt signaling pathwayGO:0016055980.017
activation of innate immune responseGO:000221840.016
muscle organ developmentGO:00075171270.016
regulation of cell deathGO:00109411730.016
intrinsic apoptotic signaling pathwayGO:0097193160.016
chorion containing eggshell formationGO:00073041050.016
anterior posterior axis specification embryoGO:00085951030.016
humoral immune responseGO:00069591170.016
positive regulation of catabolic processGO:00098961050.016
response to ionizing radiationGO:0010212320.016
single organism biosynthetic processGO:00447112060.016
organophosphate metabolic processGO:00196371950.016
open tracheal system developmentGO:00074242040.016
signal transduction by phosphorylationGO:00230141070.016
positive regulation of immune responseGO:0050778630.016
positive regulation of cell migrationGO:003033520.016
male sex differentiationGO:0046661250.016
positive regulation of cellular catabolic processGO:0031331950.015
eye morphogenesisGO:00485922600.015
ribonucleotide metabolic processGO:00092591450.015
translationGO:0006412690.015
defense response to gram negative bacteriumGO:0050829940.015
regulation of translationGO:0006417560.015
sensory organ morphogenesisGO:00905962600.015
salivary gland histolysisGO:0035070880.015
mitotic spindle organizationGO:00070522200.015
cell type specific apoptotic processGO:0097285380.015
protein targetingGO:0006605640.015
body morphogenesisGO:001017120.015
tube developmentGO:00352952440.015
positive regulation of cell differentiationGO:0045597640.015
positive regulation of phosphorylationGO:0042327870.015
response to heatGO:0009408630.015
regulation of small gtpase mediated signal transductionGO:0051056930.015
regulation of secretion by cellGO:1903530390.015
cellular protein catabolic processGO:0044257830.015
macromolecular complex assemblyGO:00650032560.015
nurse cell apoptotic processGO:0045476170.015
positive regulation of defense responseGO:0031349590.015
regulation of cellular ketone metabolic processGO:001056530.014
regulation of neuron apoptotic processGO:0043523160.014
nitrogen compound transportGO:0071705850.014
mitotic nuclear divisionGO:00070672130.014
developmental growthGO:00485892800.014
antimicrobial humoral responseGO:0019730990.014
compound eye morphogenesisGO:00017452490.014
protein import into nucleusGO:0006606510.014
chromatin organizationGO:00063252070.014
signal transduction in response to dna damageGO:004277030.014
ectopic germ cell programmed cell deathGO:003523480.014
regulation of cell divisionGO:0051302720.014
response to glucoseGO:000974920.014
salivary gland cell autophagic cell deathGO:0035071830.014
locomotory behaviorGO:00076261760.013
nucleus organizationGO:0006997450.013
single organism membrane organizationGO:0044802930.013
positive regulation of programmed cell deathGO:0043068620.013
regulation of wnt signaling pathwayGO:0030111680.013
regulation of chromosome organizationGO:0033044640.013
eggshell formationGO:00307031050.013
endosome to lysosome transportGO:000833370.013
regulation of cell proliferationGO:00421271630.013
negative regulation of nervous system developmentGO:0051961920.013
eye developmentGO:00016543230.013
positive regulation of immune system processGO:0002684680.013
regulation of nuclear divisionGO:0051783580.013
regulation of cell cycle processGO:00105641810.013
gonad developmentGO:0008406500.013
stem cell developmentGO:0048864790.013
oxoacid metabolic processGO:00434361030.013
heterocycle catabolic processGO:00467001660.013
negative regulation of transcription dna templatedGO:00458922370.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
embryonic pattern specificationGO:00098801740.013
regulation of intracellular transportGO:0032386640.013
agingGO:00075681430.012
regulation of nervous system developmentGO:00519602480.012
regulation of developmental growthGO:00486381740.012
negative regulation of cellular metabolic processGO:00313243820.012
negative regulation of programmed cell deathGO:0043069720.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
pole plasm assemblyGO:0007315610.012
instar larval developmentGO:0002168550.012
nuclear divisionGO:00002803320.012
nucleobase containing compound catabolic processGO:00346551650.012
developmental cell growthGO:0048588520.012
positive regulation of cellular amine metabolic processGO:003324000.012
protein localization to nucleusGO:0034504550.012
positive regulation of macroautophagyGO:001623980.012
positive regulation of neurogenesisGO:0050769410.012
intracellular mrna localization involved in pattern specification processGO:0060810560.012
neuromuscular synaptic transmissionGO:0007274670.012
purine ribonucleotide catabolic processGO:00091541090.012
carboxylic acid metabolic processGO:0019752920.011
mitochondrion organizationGO:0007005650.011
protein complex biogenesisGO:00702712010.011
cellular component assembly involved in morphogenesisGO:00109271510.011
olfactory learningGO:0008355560.011
oocyte dorsal ventral axis specificationGO:0007310340.011
amine metabolic processGO:0009308120.011
protein targeting to nucleusGO:0044744510.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
maintenance of locationGO:0051235730.011
aromatic compound catabolic processGO:00194391660.011
immune response regulating signaling pathwayGO:000276420.011
columnar cuboidal epithelial cell developmentGO:00020662490.011
rna processingGO:00063961470.011
response to organic cyclic compoundGO:0014070890.011
adult behaviorGO:00305341370.011
cellular macromolecule catabolic processGO:00442651360.011
regulation of mrna processingGO:0050684710.011
regulation of anatomical structure sizeGO:00900661630.011
regulation of innate immune responseGO:0045088710.011
dendrite developmentGO:00163582040.011
regulation of mitotic metaphase anaphase transitionGO:0030071260.011
reproductive structure developmentGO:0048608740.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
positive regulation of cellular component organizationGO:00511301560.011
biological adhesionGO:00226101380.011
organic acid metabolic processGO:00060821030.011
eggshell chorion assemblyGO:0007306660.011
dendrite morphogenesisGO:00488131990.011
regulation of multicellular organismal developmentGO:20000264140.011
rna localizationGO:00064031150.010
positive regulation of mapk cascadeGO:0043410630.010
membrane fusionGO:0061025420.010
regulation of protein stabilityGO:0031647430.010
axis specificationGO:00097981670.010
single organism behaviorGO:00447083910.010
tissue homeostasisGO:0001894360.010
ameboidal type cell migrationGO:00016671510.010
macromolecule methylationGO:0043414450.010
chemosensory behaviorGO:00076351060.010
nuclear transportGO:0051169720.010
cellular response to oxygen containing compoundGO:1901701790.010
cell migrationGO:00164772380.010

EndoG disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.092
nervous system diseaseDOID:86300.014
central nervous system diseaseDOID:33100.013
neurodegenerative diseaseDOID:128900.011
disease of metabolismDOID:001466700.010
inherited metabolic disorderDOID:65500.010