Drosophila melanogaster

65 known processes

HPS4 (Dmel_CG4966)

Hermansky-Pudlak Syndrome 4 ortholog

(Aliases: Dmel\CG4966,dHPS4,CG4966)

HPS4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of response to stimulusGO:00485843230.107
phosphorylationGO:00163102940.079
positive regulation of cell communicationGO:00106472500.070
ion transmembrane transportGO:00342201220.061
positive regulation of signalingGO:00230562430.061
positive regulation of signal transductionGO:00099672230.058
cellular protein modification processGO:00064644380.056
proteolysisGO:00065081920.052
cellular catabolic processGO:00442483720.052
intracellular signal transductionGO:00355563000.051
regulation of intracellular signal transductionGO:19025312360.050
neurological system processGO:00508773580.048
organic substance catabolic processGO:19015753080.047
organic substance transportGO:00717022570.046
chromosome organizationGO:00512763600.041
macromolecule catabolic processGO:00090571610.041
cellular macromolecule catabolic processGO:00442651360.040
ion transportGO:00068111450.040
establishment of localization in cellGO:00516494020.040
regulation of phosphorus metabolic processGO:00511742100.039
body morphogenesisGO:001017120.038
monocarboxylic acid transportGO:001571830.038
cellular response to dna damage stimulusGO:00069742230.037
cellular protein catabolic processGO:0044257830.037
catabolic processGO:00090564090.037
single organism intracellular transportGO:19025822070.036
positive regulation of intracellular signal transductionGO:19025331160.036
protein modification processGO:00362114380.036
vesicle mediated transportGO:00161923810.034
regulation of localizationGO:00328792750.033
positive regulation of macromolecule metabolic processGO:00106044050.033
proteolysis involved in cellular protein catabolic processGO:0051603830.032
small molecule metabolic processGO:00442813050.030
immune response regulating signaling pathwayGO:000276420.030
protein modification by small protein conjugation or removalGO:00706471060.030
chromatin organizationGO:00063252070.029
positive regulation of phosphorus metabolic processGO:00105621390.029
organonitrogen compound metabolic processGO:19015643180.029
imaginal disc derived appendage morphogenesisGO:00351143950.028
positive regulation of phosphate metabolic processGO:00459371390.028
single organism catabolic processGO:00447122280.028
regulation of phosphorylationGO:00423251470.028
cellular nitrogen compound catabolic processGO:00442701650.027
positive regulation of transportGO:0051050920.027
response to glucoseGO:000974920.027
regulation of phosphate metabolic processGO:00192202100.026
heterocycle catabolic processGO:00467001660.025
regulation of transportGO:00510491810.025
cell migrationGO:00164772380.025
organophosphate metabolic processGO:00196371950.025
response to monosaccharideGO:003428440.024
positive regulation of multicellular organismal processGO:00512401430.024
nucleobase containing compound catabolic processGO:00346551650.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
response to hexoseGO:000974630.023
ocellus pigment metabolic processGO:0046158190.023
modification dependent protein catabolic processGO:0019941780.023
immune response activating signal transductionGO:000275720.023
regulation of cell cycleGO:00517262910.022
positive regulation of phosphorylationGO:0042327870.022
appendage developmentGO:00487364010.022
secondary metabolite biosynthetic processGO:0044550240.022
response to abiotic stimulusGO:00096283410.022
regulation of mapk cascadeGO:0043408920.021
ommochrome biosynthetic processGO:0006727190.021
central nervous system developmentGO:00074172010.021
localization of cellGO:00516742570.021
organic cyclic compound catabolic processGO:19013611680.021
imaginal disc derived appendage developmentGO:00487373990.020
carbohydrate derivative metabolic processGO:19011352170.020
ubiquitin dependent protein catabolic processGO:0006511780.020
mapk cascadeGO:00001651070.020
modification dependent macromolecule catabolic processGO:0043632790.020
positive regulation of cell migrationGO:003033520.020
negative regulation of cell communicationGO:00106482230.020
regulation of protein metabolic processGO:00512462560.019
organic acid metabolic processGO:00060821030.019
forebrain developmentGO:003090020.019
negative regulation of signal transductionGO:00099682060.019
protein catabolic processGO:00301631010.019
ribonucleotide catabolic processGO:00092611090.019
regulation of response to stressGO:00801342000.019
inorganic ion transmembrane transportGO:0098660730.019
kidney developmentGO:000182230.019
chromatin modificationGO:00165681470.019
carboxylic acid metabolic processGO:0019752920.019
aromatic compound catabolic processGO:00194391660.019
signal transduction by phosphorylationGO:00230141070.019
regulation of epithelial cell proliferationGO:005067840.019
regulation of cellular ketone metabolic processGO:001056530.019
pigment metabolic process involved in developmental pigmentationGO:0043324330.018
cellular amino acid metabolic processGO:0006520610.018
positive regulation of cellular protein metabolic processGO:00322701180.018
single organism behaviorGO:00447083910.018
response to organic substanceGO:00100332840.018
response to biotic stimulusGO:00096072940.018
axon cargo transportGO:0008088290.018
secretion by cellGO:00329401010.018
positive regulation of nucleobase containing compound metabolic processGO:00459353320.018
nucleobase containing small molecule metabolic processGO:00550861740.017
small gtpase mediated signal transductionGO:0007264880.017
actin filament based processGO:00300292200.017
protein ubiquitinationGO:0016567700.017
nucleoside phosphate metabolic processGO:00067531620.017
microtubule based transportGO:0010970420.017
ommochrome metabolic processGO:0046152190.017
innate immune response activating signal transductionGO:000275820.017
positive regulation of cell motilityGO:200014730.017
positive regulation of catalytic activityGO:00430851180.017
phosphatidylethanolamine metabolic processGO:004633710.017
protein modification by small protein removalGO:0070646280.016
regulation of cellular catabolic processGO:00313291570.016
actin cytoskeleton organizationGO:00300362060.016
intracellular transportGO:00469072280.016
protein transportGO:00150311550.016
single organism biosynthetic processGO:00447112060.016
cellular homeostasisGO:0019725800.016
regulation of cellular amino acid metabolic processGO:000652100.016
cell fate determinationGO:0001709910.016
positive regulation of cellular biosynthetic processGO:00313283160.016
cellular response to hexose stimulusGO:007133110.016
regulation of nervous system developmentGO:00519602480.016
protein phosphorylationGO:00064681690.016
regulation of cellular amine metabolic processGO:003323830.016
cellular response to chemical stimulusGO:00708871990.016
regulation of cell differentiationGO:00455953020.016
purine containing compound metabolic processGO:00725211550.016
mitotic nuclear divisionGO:00070672130.016
metal ion transportGO:0030001740.016
transcription from rna polymerase ii promoterGO:00063663680.016
regulation of immune system processGO:00026821760.016
mesenchymal cell differentiationGO:004876210.016
epithelial cell developmentGO:00020642740.015
regulation of mitotic cell cycleGO:00073461900.015
carbohydrate derivative catabolic processGO:19011361180.015
axis specificationGO:00097981670.015
transmembrane transportGO:00550851390.015
response to radiationGO:00093141550.015
regulation of multicellular organismal developmentGO:20000264140.015
nucleotide catabolic processGO:00091661090.015
germarium derived egg chamber formationGO:00072931010.015
regulation of cellular component biogenesisGO:00440872010.015
posttranscriptional regulation of gene expressionGO:00106081450.015
protein localizationGO:00081042840.015
organonitrogen compound catabolic processGO:19015651280.015
segmentationGO:00352822070.015
negative regulation of immune system processGO:0002683500.015
cell deathGO:00082192790.015
salivary gland developmentGO:00074311620.015
response to lipopolysaccharideGO:003249640.015
regulation of molecular functionGO:00650092170.015
regionalizationGO:00030024160.015
nucleotide metabolic processGO:00091171610.015
regulation of neurogenesisGO:00507671580.015
limb developmentGO:006017310.015
endosomal transportGO:0016197440.015
cation transmembrane transportGO:0098655880.015
establishment of protein localizationGO:00451841630.015
cytoplasmic transportGO:00164821300.014
positive regulation of biosynthetic processGO:00098913160.014
positive regulation of catabolic processGO:00098961050.014
regulation of ras protein signal transductionGO:0046578930.014
regulation of cell cycle processGO:00105641810.014
cytoskeleton dependent intracellular transportGO:0030705440.014
cation transportGO:00068121100.014
spermatogenesisGO:00072832000.014
programmed cell deathGO:00125012570.014
endocytosisGO:00068973100.014
phagocytosisGO:00069092150.014
regulation of lipid transportGO:003236830.014
rna processingGO:00063961470.014
positive regulation of molecular functionGO:00440931360.014
negative regulation of developmental processGO:00510932010.014
wing disc morphogenesisGO:00074723440.014
somatic muscle developmentGO:0007525660.014
regulation of synapse organizationGO:00508071100.014
regulation of immune responseGO:00507761180.014
cell divisionGO:00513012480.014
regulation of anatomical structure morphogenesisGO:00226032420.014
purine ribonucleotide catabolic processGO:00091541090.013
stem cell differentiationGO:00488631170.013
proteasomal protein catabolic processGO:0010498590.013
pigment biosynthetic processGO:0046148360.013
homeostatic processGO:00425921990.013
jak stat cascadeGO:0007259490.013
positive regulation of cellular catabolic processGO:0031331950.013
histone modificationGO:00165701060.013
response to external biotic stimulusGO:00432072930.013
regulation of cell deathGO:00109411730.013
adult behaviorGO:00305341370.013
digestive system developmentGO:00551231490.013
immune system processGO:00023763470.013
organophosphate catabolic processGO:00464341120.013
telencephalon developmentGO:002153720.013
regulation of cellular protein metabolic processGO:00322682430.013
epithelial cell differentiationGO:00308553220.013
compound eye developmentGO:00487493070.013
negative regulation of signalingGO:00230572190.013
purine nucleoside catabolic processGO:00061521120.013
long chain fatty acid metabolic processGO:000167630.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
cellular response to carbohydrate stimulusGO:007132240.012
spindle organizationGO:00070512530.012
ocellus pigmentationGO:0033060190.012
synapse organizationGO:00508081960.012
positive regulation of hydrolase activityGO:0051345780.012
nitrogen compound transportGO:0071705850.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
axon developmentGO:00615642970.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
camera type eye developmentGO:004301040.012
oxoacid metabolic processGO:00434361030.012
mesenchymal cell developmentGO:001403110.012
intracellular protein transportGO:00068861040.012
purine ribonucleoside catabolic processGO:00461301120.012
nucleocytoplasmic transportGO:0006913720.012
response to other organismGO:00517072930.012
exocrine system developmentGO:00352721620.012
organelle fissionGO:00482853400.012
response to oxygen containing compoundGO:19017002000.012
ras protein signal transductionGO:0007265880.012
negative regulation of response to stimulusGO:00485852580.012
covalent chromatin modificationGO:00165691060.012
purine ribonucleoside metabolic processGO:00461281270.012
cell motilityGO:00488702510.012
regulation of protein transportGO:0051223570.012
cellular response to biotic stimulusGO:007121640.011
regulation of cell developmentGO:00602842150.011
positive regulation of cell deathGO:0010942690.011
positive regulation of cellular amine metabolic processGO:003324000.011
taxisGO:00423303040.011
protein complex biogenesisGO:00702712010.011
imaginal disc derived wing morphogenesisGO:00074763370.011
cellularizationGO:0007349900.011
regulation of protein localizationGO:0032880760.011
organelle assemblyGO:00709251980.011
mitotic spindle organizationGO:00070522200.011
salivary gland morphogenesisGO:00074351450.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
regulation of cellular localizationGO:00603411360.011
developmental programmed cell deathGO:00106231380.011
nucleoside catabolic processGO:00091641120.011
deathGO:00162652840.011
cellular response to lipopolysaccharideGO:007122230.011
microtubule based movementGO:0007018510.011
cellular ketone metabolic processGO:0042180240.011
post embryonic appendage morphogenesisGO:00351203850.011
purine containing compound catabolic processGO:00725231120.011
response to extracellular stimulusGO:00099911160.011
peptidyl threonine phosphorylationGO:001810720.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
positive regulation of protein metabolic processGO:00512471280.011
neuroblast proliferationGO:0007405740.011
positive regulation of mapk cascadeGO:0043410630.011
cellular response to monosaccharide stimulusGO:007132620.011
regulation of vesicle mediated transportGO:0060627590.011
ribonucleoside metabolic processGO:00091191270.011
stem cell proliferationGO:0072089880.011
germ line stem cell maintenanceGO:0030718500.011
regulation of catabolic processGO:00098941700.011
negative regulation of cell differentiationGO:00455961430.011
nucleoside triphosphate catabolic processGO:00091431080.011
developmental maturationGO:00217001720.011
regulation of catalytic activityGO:00507901850.011
cellular response to molecule of bacterial originGO:007121930.011
muscle structure developmentGO:00610612240.010
cellular response to organic substanceGO:00713101320.010
sulfur compound metabolic processGO:0006790590.010
regulation of proteolysisGO:0030162870.010
organic acid transportGO:0015849180.010
stem cell maintenanceGO:0019827670.010
cytokinesisGO:0000910900.010
protein complex assemblyGO:00064612000.010
purine nucleoside metabolic processGO:00422781270.010
embryonic pattern specificationGO:00098801740.010
hormone catabolic processGO:004244730.010
regulation of response to external stimulusGO:00321011150.010
regulation of synapse structure and activityGO:00508031280.010
inorganic cation transmembrane transportGO:0098662610.010
positive regulation of lipid metabolic processGO:004583440.010
synaptic vesicle localizationGO:0097479530.010
regulation of protein modification processGO:00313991120.010
tripartite regional subdivisionGO:00073511030.010
purine nucleotide catabolic processGO:00061951090.010
compound eye morphogenesisGO:00017452490.010
erk1 and erk2 cascadeGO:0070371390.010
positive regulation of jun kinase activityGO:004350740.010
dna metabolic processGO:00062592270.010
appendage morphogenesisGO:00351073970.010
pigment metabolic process involved in pigmentationGO:0043474330.010
organelle localizationGO:00516401480.010
negative regulation of nervous system developmentGO:0051961920.010

HPS4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
nervous system diseaseDOID:86300.037
disease of metabolismDOID:001466700.018
central nervous system diseaseDOID:33100.016
inherited metabolic disorderDOID:65500.013
sensory system diseaseDOID:005015500.013
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
neurodegenerative diseaseDOID:128900.010