Drosophila melanogaster

87 known processes

twe (Dmel_CG4965)

twine

(Aliases: mat(2)synHB5,Dmel\CG4965,TWINE,Twe,Cdc25,twn,l(2)35Fh,CG4965,mat(2)syn-A,mat(2)syn[HB5],BG:DS02740.1,cdc25)

twe biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiotic nuclear divisionGO:00071261511.000
meiotic cell cycle processGO:19030461320.998
meiotic cell cycleGO:00513211710.995
organelle fissionGO:00482853400.995
nuclear divisionGO:00002803320.994
female meiotic divisionGO:0007143700.993
meiotic spindle organizationGO:0000212360.985
meiosis iGO:0007127590.984
Mouse
cell cycle comprising mitosis without cytokinesisGO:0033301250.976
spindle assembly involved in female meiosisGO:0007056140.974
spindle organizationGO:00070512530.964
male meiosisGO:0007140520.938
spindle assembly involved in meiosisGO:0090306200.918
male meiosis cytokinesisGO:0007112260.885
organelle assemblyGO:00709251980.862
meiotic chromosome segregationGO:0045132590.860
meiotic cytokinesisGO:0033206330.829
oocyte developmentGO:00485991240.794
Mouse
meiosis iiGO:0007135230.785
pole cell formationGO:0007279190.758
nucleus organizationGO:0006997450.730
cytokinesisGO:0000910900.729
Human
syncytial blastoderm mitotic cell cycleGO:0035186210.723
spindle assembly involved in female meiosis iGO:000705750.716
centrosome cycleGO:00070981370.681
Fly
pole cell developmentGO:0007277260.618
oocyte differentiationGO:00099941450.615
Mouse
cytoskeleton dependent cytokinesisGO:0061640810.612
cell divisionGO:00513012480.529
Human Worm
female meiosis iGO:000714480.500
Mouse
protein complex biogenesisGO:00702712010.493
protein complex assemblyGO:00064612000.488
nucleus localizationGO:0051647340.448
mitotic cell cycle embryonicGO:0045448380.402
reciprocal meiotic recombinationGO:0007131190.371
pronuclear migrationGO:003504640.368
cell maturationGO:00484691440.358
Mouse
mitotic spindle organizationGO:00070522200.347
chromosome organizationGO:00512763600.341
female meiosis chromosome segregationGO:0016321330.323
oocyte constructionGO:00073081120.314
spindle assemblyGO:0051225800.299
centrosome duplicationGO:00512981210.283
Fly
single fertilizationGO:0007338240.271
microtubule polymerization or depolymerizationGO:0031109390.262
dorsal appendage formationGO:0046843470.236
chromosome segregationGO:00070591570.221
organelle localizationGO:00516401480.191
oocyte axis specificationGO:00073091080.181
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.163
regulation of cell cycleGO:00517262910.154
long term memoryGO:0007616620.149
fertilizationGO:0009566260.136
microtubule organizing center organizationGO:00310231680.134
Fly
stem cell divisionGO:0017145690.133
regionalizationGO:00030024160.129
centrosome separationGO:0051299200.128
synaptic transmissionGO:00072682880.121
embryonic pattern specificationGO:00098801740.121
segmentationGO:00352822070.118
catabolic processGO:00090564090.109
regulation of protein complex disassemblyGO:0043244290.106
male gamete generationGO:00482322010.105
meiotic sister chromatid segregationGO:004514460.102
regulation of microtubule based processGO:0032886490.102
neuronal stem cell divisionGO:0036445350.098
cellular catabolic processGO:00442483720.095
meiotic chromosome condensationGO:001003230.095
regulation of spindle organizationGO:0090224170.094
modification dependent protein catabolic processGO:0019941780.093
asymmetric stem cell divisionGO:0098722490.092
embryonic axis specificationGO:00005781070.089
mitotic spindle stabilizationGO:004314860.088
oocyte anterior posterior axis specificationGO:0007314720.086
cellular protein complex disassemblyGO:0043624350.084
positive regulation of molecular functionGO:00440931360.080
Mouse
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.079
asymmetric cell divisionGO:0008356370.078
single organism cellular localizationGO:19025801800.078
centrosome organizationGO:00512971630.078
Fly
eggshell chorion assemblyGO:0007306660.077
regulation of cytoskeleton organizationGO:0051493890.076
blastoderm segmentationGO:00073501590.076
actin cytoskeleton organizationGO:00300362060.075
cellular component assembly involved in morphogenesisGO:00109271510.074
brain developmentGO:00074201200.073
axis specificationGO:00097981670.072
macromolecule catabolic processGO:00090571610.072
oocyte dorsal ventral axis specificationGO:0007310340.070
maintenance of locationGO:0051235730.070
cell cycle phase transitionGO:00447701400.067
Human Yeast Zebrafish Fly
maintenance of location in cellGO:0051651280.064
cellularizationGO:0007349900.061
establishment of localization in cellGO:00516494020.060
protein polymerizationGO:0051258420.060
establishment of nucleus localizationGO:0040023260.060
protein complex disassemblyGO:0043241360.059
negative regulation of protein metabolic processGO:0051248850.057
chromosome movement towards spindle poleGO:005130540.055
intracellular mrna localizationGO:0008298660.055
proteolysis involved in cellular protein catabolic processGO:0051603830.053
regulation of mitotic spindle organizationGO:006023690.052
neural precursor cell proliferationGO:0061351750.051
protein localizationGO:00081042840.050
cell deathGO:00082192790.050
Worm
macromolecular complex assemblyGO:00650032560.048
regulation of multicellular organismal developmentGO:20000264140.048
protein modification by small protein conjugationGO:0032446790.048
chemical homeostasisGO:0048878920.048
ubiquitin dependent protein catabolic processGO:0006511780.047
neuroblast divisionGO:0055057350.046
organonitrogen compound metabolic processGO:19015643180.045
regulation of pole plasm oskar mrna localizationGO:0007317270.045
mitotic cytokinesisGO:0000281500.044
anterior posterior axis specification embryoGO:00085951030.044
response to oxidative stressGO:0006979860.043
attachment of spindle microtubules to kinetochoreGO:000860850.043
mitotic cell cycle checkpointGO:0007093880.043
regulation of mitotic cell cycleGO:00073461900.043
negative regulation of mitotic cell cycle phase transitionGO:19019911030.042
regulation of oocyte developmentGO:0060281270.041
protein catabolic processGO:00301631010.041
homeostatic processGO:00425921990.041
digestive tract mesoderm developmentGO:000750250.040
regulation of catalytic activityGO:00507901850.039
Yeast Mouse
cellular protein modification processGO:00064644380.039
Human Yeast Mouse Fly
regulation of multi organism processGO:00439001310.039
regulation of microtubule cytoskeleton organizationGO:0070507410.038
regulation of nervous system developmentGO:00519602480.037
tripartite regional subdivisionGO:00073511030.037
protein depolymerizationGO:0051261310.037
proteasomal protein catabolic processGO:0010498590.036
antimicrobial humoral responseGO:0019730990.036
mitotic cell cycle phase transitionGO:00447721380.035
Human Yeast Zebrafish Fly
cellular protein catabolic processGO:0044257830.035
modification dependent macromolecule catabolic processGO:0043632790.034
regulation of hemocyte proliferationGO:0035206370.034
male meiosis chromosome segregationGO:0007060100.034
cellular component disassemblyGO:0022411460.034
response to organic substanceGO:00100332840.033
establishment of organelle localizationGO:00516561220.033
membrane organizationGO:00610241120.032
synapse organizationGO:00508081960.032
positive regulation of nucleobase containing compound metabolic processGO:00459353320.032
small molecule metabolic processGO:00442813050.032
oocyte maturationGO:000155630.031
Mouse
positive regulation of nitrogen compound metabolic processGO:00511733540.031
establishment or maintenance of cell polarityGO:00071631670.031
regulation of embryonic developmentGO:0045995680.030
somatic stem cell divisionGO:0048103370.029
cuticle developmentGO:0042335860.029
regulation of microtubule polymerization or depolymerizationGO:0031110270.029
spindle stabilizationGO:0043146140.029
organic substance catabolic processGO:19015753080.029
chromosome organization involved in meiosisGO:0070192100.028
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.028
cystoblast divisionGO:0007282100.028
regulation of organelle organizationGO:00330431960.028
carbohydrate derivative metabolic processGO:19011352170.028
sensory organ precursor cell divisionGO:0045035100.028
cellular protein complex assemblyGO:0043623710.028
establishment of spindle localizationGO:0051293220.027
nuclear migrationGO:0007097200.027
negative regulation of macromolecule biosynthetic processGO:00105582700.026
negative regulation of gene expressionGO:00106293870.026
endomembrane system organizationGO:00102561190.025
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.024
protein modification by small protein conjugation or removalGO:00706471060.024
spindle localizationGO:0051653220.024
asymmetric neuroblast divisionGO:0055059330.023
cellular macromolecule catabolic processGO:00442651360.023
response to gravityGO:0009629260.023
positive regulation of macromolecule metabolic processGO:00106044050.022
Mouse
brain morphogenesisGO:0048854160.021
single organism membrane organizationGO:0044802930.021
developmental maturationGO:00217001720.021
Mouse
negative regulation of cellular biosynthetic processGO:00313272770.020
vesicle mediated transportGO:00161923810.020
Worm
maternal determination of anterior posterior axis embryoGO:0008358740.020
regulation of molecular functionGO:00650092170.019
Yeast Mouse
regulation of chromatin silencingGO:0031935360.019
negative regulation of mitotic cell cycleGO:00459301090.019
Worm Fly
ovarian fusome organizationGO:0030723110.019
cellular macromolecule localizationGO:00707272200.019
proteolysisGO:00065081920.019
meiotic cell cycle phase transitionGO:004477140.019
positive regulation of catalytic activityGO:00430851180.019
Mouse
gene silencingGO:00164581380.018
eggshell formationGO:00307031050.018
translationGO:0006412690.018
protein modification processGO:00362114380.018
Human Yeast Mouse Fly
centriole centriole cohesionGO:001045750.018
positive regulation of nervous system developmentGO:0051962690.017
nuclear envelope organizationGO:000699870.017
organic substance transportGO:00717022570.017
single organism catabolic processGO:00447122280.017
establishment of meiotic spindle orientationGO:005129620.017
germarium derived oocyte differentiationGO:0030706290.017
actin filament organizationGO:00070151260.017
intracellular transportGO:00469072280.017
regulation of protein metabolic processGO:00512462560.017
Yeast Mouse
rhythmic processGO:00485111060.016
positive regulation of cellular component organizationGO:00511301560.016
reciprocal dna recombinationGO:0035825190.016
negative regulation of rna metabolic processGO:00512532510.016
negative regulation of cytoskeleton organizationGO:0051494300.016
immune responseGO:00069552460.016
cellular nitrogen compound catabolic processGO:00442701650.016
ribose phosphate metabolic processGO:00196931450.016
maintenance of protein location in cellGO:0032507260.016
regulation of cellular localizationGO:00603411360.015
intercellular bridge organizationGO:0043063140.015
chorion containing eggshell formationGO:00073041050.015
regulation of protein modification processGO:00313991120.015
Yeast Mouse
anterior posterior pattern specificationGO:00099521360.015
chromosome separationGO:0051304420.015
cellular response to chemical stimulusGO:00708871990.015
regulation of mitotic spindle elongationGO:003288810.014
centrosome localizationGO:0051642140.014
response to sterolGO:0036314340.014
intracellular mrna localization involved in pattern specification processGO:0060810560.014
dorsal ventral pattern formationGO:00099531330.014
endocytosisGO:00068973100.014
Worm
microtubule anchoringGO:0034453110.014
response to oxygen containing compoundGO:19017002000.014
regulation of mitotic cell cycle phase transitionGO:19019901300.014
Zebrafish
purine nucleoside triphosphate catabolic processGO:00091461080.014
negative regulation of signalingGO:00230572190.013
cellular macromolecular complex assemblyGO:00346221530.013
sister chromatid segregationGO:0000819920.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
macromolecular complex disassemblyGO:0032984370.013
response to ecdysoneGO:0035075340.013
organic acid metabolic processGO:00060821030.013
negative regulation of protein depolymerizationGO:1901880230.013
microtubule polymerizationGO:0046785150.013
male meiosis iGO:000714190.013
positive regulation of mitotic sister chromatid separationGO:1901970100.013
dna damage checkpointGO:0000077780.013
mitotic sister chromatid segregationGO:0000070870.013
rna localizationGO:00064031150.012
distributive segregationGO:003283760.012
cell cycle checkpointGO:0000075950.012
negative regulation of oskar mrna translationGO:000731950.012
microtubule depolymerizationGO:0007019250.012
negative regulation of microtubule depolymerizationGO:0007026210.012
neuroblast proliferationGO:0007405740.012
organophosphate metabolic processGO:00196371950.012
actin filament based processGO:00300292200.012
protein ubiquitinationGO:0016567700.012
regulation of meiosisGO:004002030.012
response to abiotic stimulusGO:00096283410.012
Human
central nervous system developmentGO:00074172010.012
maintenance of protein locationGO:0045185280.011
regulation of notch signaling pathwayGO:00085931000.011
nucleoside triphosphate metabolic processGO:00091411200.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
aromatic compound catabolic processGO:00194391660.011
gland developmentGO:00487321910.011
establishment of cell polarityGO:0030010400.011
positive regulation of catabolic processGO:00098961050.011
negative regulation of cellular protein metabolic processGO:0032269850.011
heterocycle catabolic processGO:00467001660.011
negative regulation of cellular metabolic processGO:00313243820.011
olfactory behaviorGO:0042048970.011
g2 dna damage checkpointGO:0031572690.011
imaginal disc derived appendage developmentGO:00487373990.011
striated muscle cell developmentGO:0055002500.011
establishment or maintenance of apical basal cell polarityGO:0035088340.011
meiotic g2 mi transitionGO:000831530.011
ras protein signal transductionGO:0007265880.011
regulation of cell developmentGO:00602842150.010
positive regulation of phosphorus metabolic processGO:00105621390.010
Mouse
regulation of microtubule depolymerizationGO:0031114240.010
organic cyclic compound catabolic processGO:19013611680.010
purine ribonucleotide catabolic processGO:00091541090.010
humoral immune responseGO:00069591170.010

twe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.033
cancerDOID:16200.021
disease of anatomical entityDOID:700.012