IMP: Integrative Multi-species Prediction

Drosophila melanogaster

15 known processes

CG12042 (Dmel_CG12042)

CG12042 gene product from transcript CG12042-RA

(Aliases: Dmel\CG12042)

Entrez: 35709
FLYBASE: FBgn0033206
UniProtKB: Q7K130

Process Predictions
Disease Predictions

CG12042 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
protein prenylation	GO:0018342	3	0.601
establishment of localization in cell	GO:0051649	402	0.392
intracellular transport	GO:0046907	228	0.358
negative regulation of gene expression	GO:0010629	387	0.340
organelle fission	GO:0048285	340	0.332
positive regulation of gene expression	GO:0010628	290	0.270
protein localization	GO:0008104	284	0.264
regulation of cell proliferation	GO:0042127	163	0.260
positive regulation of rna metabolic process	GO:0051254	271	0.248
spindle assembly	GO:0051225	80	0.226
establishment of protein localization	GO:0045184	163	0.184
vesicle mediated transport	GO:0016192	381	0.178
regulation of developmental growth	GO:0048638	174	0.177
appendage morphogenesis	GO:0035107	397	0.157
positive regulation of macromolecule metabolic process	GO:0010604	405	0.147
synaptic transmission	GO:0007268	288	0.140
single organism intracellular transport	GO:1902582	207	0.136
rna localization	GO:0006403	115	0.126
protein transport	GO:0015031	155	0.117
nuclear division	GO:0000280	332	0.116
cellular macromolecule localization	GO:0070727	220	0.111
immune system process	GO:0002376	347	0.109
mitotic spindle organization	GO:0007052	220	0.107
single organism cellular localization	GO:1902580	180	0.102
gene silencing	GO:0016458	138	0.102
negative regulation of cellular biosynthetic process	GO:0031327	277	0.100
epithelial cell differentiation	GO:0030855	322	0.099
cytoplasmic transport	GO:0016482	130	0.095
negative regulation of rna metabolic process	GO:0051253	251	0.091
establishment or maintenance of cell polarity	GO:0007163	167	0.087
positive regulation of multicellular organismal process	GO:0051240	143	0.087
immune response	GO:0006955	246	0.086
microtubule based transport	GO:0010970	42	0.078
positive regulation of developmental growth	GO:0048639	62	0.077
embryo development ending in birth or egg hatching	GO:0009792	152	0.077
positive regulation of developmental process	GO:0051094	143	0.077
wnt signaling pathway	GO:0016055	98	0.072
protein acylation	GO:0043543	42	0.071
tube morphogenesis	GO:0035239	191	0.071
eye development	GO:0001654	323	0.070
morphogenesis of an epithelium	GO:0002009	276	0.069
microtubule based movement	GO:0007018	51	0.065
cellular macromolecular complex assembly	GO:0034622	153	0.065
regulation of multicellular organismal development	GO:2000026	414	0.065
cell death	GO:0008219	279	0.063
intracellular protein transport	GO:0006886	104	0.061
organic substance transport	GO:0071702	257	0.061
regulation of growth	GO:0040008	233	0.060
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.059
negative regulation of biosynthetic process	GO:0009890	277	0.059
macromolecule catabolic process	GO:0009057	161	0.059
ras protein signal transduction	GO:0007265	88	0.059
peptidyl lysine acetylation	GO:0018394	39	0.058
cell proliferation	GO:0008283	299	0.055
regulation of cell cycle process	GO:0010564	181	0.055
proteolysis	GO:0006508	192	0.054
phosphorylation	GO:0016310	294	0.052
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.051
mitotic nuclear division	GO:0007067	213	0.050
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.050
appendage development	GO:0048736	401	0.049
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.049
immune response regulating signaling pathway	GO:0002764	2	0.048
tissue morphogenesis	GO:0048729	297	0.047
cellular protein localization	GO:0034613	160	0.047
phenol containing compound metabolic process	GO:0018958	57	0.047
endocytosis	GO:0006897	310	0.046
protein modification by small protein conjugation	GO:0032446	79	0.046
macromolecular complex assembly	GO:0065003	256	0.046
positive regulation of signal transduction	GO:0009967	223	0.045
cell fate determination	GO:0001709	91	0.045
regulation of cellular protein metabolic process	GO:0032268	243	0.044
synapse organization	GO:0050808	196	0.043
regulation of protein metabolic process	GO:0051246	256	0.043
regulation of cell cycle	GO:0051726	291	0.043
positive regulation of rna biosynthetic process	GO:1902680	266	0.043
cell division	GO:0051301	248	0.042
localization of cell	GO:0051674	257	0.042
developmental growth	GO:0048589	280	0.042
organelle localization	GO:0051640	148	0.042
negative regulation of cellular metabolic process	GO:0031324	382	0.042
multicellular organism growth	GO:0035264	46	0.041
intracellular signal transduction	GO:0035556	300	0.041
notch signaling pathway	GO:0007219	120	0.041
cellular protein modification process	GO:0006464	438	0.040
rna transport	GO:0050658	46	0.040
positive regulation of growth	GO:0045927	75	0.040
organelle assembly	GO:0070925	198	0.039
digestive tract development	GO:0048565	149	0.038
response to radiation	GO:0009314	155	0.038
positive regulation of cellular biosynthetic process	GO:0031328	316	0.037
imaginal disc derived wing morphogenesis	GO:0007476	337	0.037
epithelium migration	GO:0090132	148	0.036
negative regulation of cell communication	GO:0010648	223	0.036
protein modification process	GO:0036211	438	0.036
posttranscriptional regulation of gene expression	GO:0010608	145	0.036
erk1 and erk2 cascade	GO:0070371	39	0.035
post embryonic appendage morphogenesis	GO:0035120	385	0.035
protein complex assembly	GO:0006461	200	0.035
tube development	GO:0035295	244	0.035
photoreceptor cell differentiation	GO:0046530	170	0.035
immune effector process	GO:0002252	98	0.034
regulation of mitotic cell cycle	GO:0007346	190	0.034
positive regulation of biosynthetic process	GO:0009891	316	0.034
negative regulation of cell cycle	GO:0045786	116	0.033
growth	GO:0040007	359	0.033
positive regulation of cell communication	GO:0010647	250	0.033
protein geranylgeranylation	GO:0018344	3	0.032
dendrite development	GO:0016358	204	0.032
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.032
positive regulation of protein metabolic process	GO:0051247	128	0.032
cytoskeleton dependent intracellular transport	GO:0030705	44	0.032
negative regulation of signaling	GO:0023057	219	0.032
positive regulation of transport	GO:0051050	92	0.032
small gtpase mediated signal transduction	GO:0007264	88	0.032
regulation of multicellular organism growth	GO:0040014	40	0.031
regulation of intracellular signal transduction	GO:1902531	236	0.031
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.030
regulation of molecular function	GO:0065009	217	0.030
negative regulation of signal transduction	GO:0009968	206	0.029
chromosome organization	GO:0051276	360	0.029
spinal cord development	GO:0021510	1	0.029
negative regulation of response to stimulus	GO:0048585	258	0.029
negative regulation of cell cycle process	GO:0010948	109	0.028
endomembrane system organization	GO:0010256	119	0.028
body morphogenesis	GO:0010171	2	0.028
defense response to fungus	GO:0050832	48	0.028
transcription from rna polymerase ii promoter	GO:0006366	368	0.027
skeletal muscle fiber development	GO:0048741	3	0.027
protein acetylation	GO:0006473	39	0.027
positive regulation of response to stimulus	GO:0048584	323	0.027
positive regulation of phosphorus metabolic process	GO:0010562	139	0.027
regulation of proteolysis	GO:0030162	87	0.026
regulation of cellular amine metabolic process	GO:0033238	3	0.026
positive regulation of cellular protein metabolic process	GO:0032270	118	0.026
cellular catabolic process	GO:0044248	372	0.026
compound eye morphogenesis	GO:0001745	249	0.026
regulation of immune system process	GO:0002682	176	0.025
regulation of anatomical structure morphogenesis	GO:0022603	242	0.025
negative regulation of rna biosynthetic process	GO:1902679	240	0.025
positive regulation of phosphate metabolic process	GO:0045937	139	0.025
neuron projection guidance	GO:0097485	241	0.025
sensory organ morphogenesis	GO:0090596	260	0.024
protein modification by small protein conjugation or removal	GO:0070647	106	0.024
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.024
regulation of chromosome organization	GO:0033044	64	0.023
regulation of phosphorus metabolic process	GO:0051174	210	0.023
dendrite morphogenesis	GO:0048813	199	0.023
cellular response to extracellular stimulus	GO:0031668	64	0.023
regulation of cell differentiation	GO:0045595	302	0.023
mapk cascade	GO:0000165	107	0.023
lateral inhibition	GO:0046331	206	0.023
regulation of wnt signaling pathway	GO:0030111	68	0.023
nitrogen compound transport	GO:0071705	85	0.023
spindle organization	GO:0007051	253	0.023
regulation of mapk cascade	GO:0043408	92	0.022
positive regulation of multicellular organism growth	GO:0040018	21	0.022
regulation of cellular ketone metabolic process	GO:0010565	3	0.022
cellular response to dna damage stimulus	GO:0006974	223	0.022
cellular nitrogen compound catabolic process	GO:0044270	165	0.022
nucleobase containing compound catabolic process	GO:0034655	165	0.022
response to lipopolysaccharide	GO:0032496	4	0.022
digestive tract morphogenesis	GO:0048546	127	0.021
neuromuscular junction development	GO:0007528	149	0.021
positive regulation of signaling	GO:0023056	243	0.021
cell adhesion	GO:0007155	136	0.021
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.021
protein catabolic process	GO:0030163	101	0.021
mitochondrion localization	GO:0051646	17	0.020
histone acetylation	GO:0016573	38	0.020
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.020
defense response to bacterium	GO:0042742	178	0.020
positive regulation of nervous system development	GO:0051962	69	0.020
regionalization	GO:0003002	416	0.020
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.019
myotube cell development	GO:0014904	3	0.019
regulation of phosphorylation	GO:0042325	147	0.019
cellular response to external stimulus	GO:0071496	66	0.019
response to abiotic stimulus	GO:0009628	341	0.019
imaginal disc fusion	GO:0046528	19	0.019
chemotaxis	GO:0006935	249	0.019
protein heterooligomerization	GO:0051291	4	0.018
negative regulation of epithelial cell proliferation	GO:0050680	4	0.018
wing disc morphogenesis	GO:0007472	344	0.018
protein complex biogenesis	GO:0070271	201	0.018
compound eye photoreceptor development	GO:0042051	78	0.018
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.018
humoral immune response	GO:0006959	117	0.018
cellular protein complex assembly	GO:0043623	71	0.018
imaginal disc derived appendage development	GO:0048737	399	0.018
apoptotic signaling pathway	GO:0097190	27	0.017
establishment of rna localization	GO:0051236	47	0.017
muscle structure development	GO:0061061	224	0.017
protein maturation	GO:0051604	71	0.017
regulation of cell shape	GO:0008360	113	0.017
regulation of translation	GO:0006417	56	0.017
positive regulation of transcription dna templated	GO:0045893	266	0.017
negative regulation of protein metabolic process	GO:0051248	85	0.017
autophagy	GO:0006914	108	0.017
taxis	GO:0042330	304	0.017
regulation of cellular localization	GO:0060341	136	0.016
cellular amine metabolic process	GO:0044106	12	0.016
regulation of catalytic activity	GO:0050790	185	0.016
regulation of synapse structure and activity	GO:0050803	128	0.016
response to fungus	GO:0009620	50	0.016
axon cargo transport	GO:0008088	29	0.016
cellular response to nutrient levels	GO:0031669	62	0.016
rna catabolic process	GO:0006401	37	0.016
regulation of hydrolase activity	GO:0051336	97	0.016
digestive system development	GO:0055123	149	0.016
muscle organ development	GO:0007517	127	0.015
regulation of cell death	GO:0010941	173	0.015
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.015
cellular component assembly involved in morphogenesis	GO:0010927	151	0.015
compound eye photoreceptor cell differentiation	GO:0001751	140	0.015
axon development	GO:0061564	297	0.015
regulation of organelle organization	GO:0033043	196	0.015
response to extracellular stimulus	GO:0009991	116	0.015
immune response activating signal transduction	GO:0002757	2	0.015
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.015
protein targeting	GO:0006605	64	0.015
cell cycle arrest	GO:0007050	4	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
mitotic g2 dna damage checkpoint	GO:0007095	69	0.015
internal peptidyl lysine acetylation	GO:0018393	38	0.015
cytokinesis	GO:0000910	90	0.015
morphogenesis of a polarized epithelium	GO:0001738	93	0.015
histone h4 acetylation	GO:0043967	13	0.015
membrane organization	GO:0061024	112	0.014
protein import	GO:0017038	55	0.014
negative regulation of transcription dna templated	GO:0045892	237	0.014
protein processing	GO:0016485	68	0.014
regulation of phosphate metabolic process	GO:0019220	210	0.014
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.014
male meiosis	GO:0007140	52	0.014
positive regulation of intracellular transport	GO:0032388	42	0.014
regulation of intracellular transport	GO:0032386	64	0.014
mitotic g2 m transition checkpoint	GO:0044818	70	0.014
cellular macromolecule catabolic process	GO:0044265	136	0.014
proteasomal protein catabolic process	GO:0010498	59	0.014
nuclear transport	GO:0051169	72	0.013
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.013
catabolic process	GO:0009056	409	0.013
multi organism behavior	GO:0051705	175	0.013
cellular ketone metabolic process	GO:0042180	24	0.013
camera type eye development	GO:0043010	4	0.013
negative regulation of mitotic cell cycle	GO:0045930	109	0.013
centrosome organization	GO:0051297	163	0.013
positive regulation of wnt signaling pathway	GO:0030177	25	0.013
ovarian follicle cell development	GO:0030707	248	0.013
protein secretion	GO:0009306	45	0.013
small molecule metabolic process	GO:0044281	305	0.013
secondary metabolic process	GO:0019748	75	0.013
biological adhesion	GO:0022610	138	0.013
actin filament depolymerization	GO:0030042	5	0.013
death	GO:0016265	284	0.012
phagocytosis	GO:0006909	215	0.012
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.012
regulation of transport	GO:0051049	181	0.012
positive regulation of phosphorylation	GO:0042327	87	0.012
organonitrogen compound metabolic process	GO:1901564	318	0.012
heterocycle catabolic process	GO:0046700	166	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.012
response to oxidative stress	GO:0006979	86	0.012
regulation of mrna processing	GO:0050684	71	0.012
embryonic morphogenesis	GO:0048598	206	0.012
regulation of endopeptidase activity	GO:0052548	36	0.012
negative regulation of cellular protein metabolic process	GO:0032269	85	0.012
compound eye development	GO:0048749	307	0.012
protein kinase b signaling	GO:0043491	1	0.012
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.012
epithelial cell development	GO:0002064	274	0.012
response to organic substance	GO:0010033	284	0.012
positive regulation of erk1 and erk2 cascade	GO:0070374	36	0.012
regulation of cellular amino acid metabolic process	GO:0006521	0	0.012
aromatic compound catabolic process	GO:0019439	166	0.011
photoreceptor cell development	GO:0042461	96	0.011
regulation of erk1 and erk2 cascade	GO:0070372	39	0.011
regulation of phosphatase activity	GO:0010921	3	0.011
response to nutrient levels	GO:0031667	114	0.011
cellular response to molecule of bacterial origin	GO:0071219	3	0.011
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.011
regulation of response to stress	GO:0080134	200	0.011
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.011
nucleobase containing compound transport	GO:0015931	56	0.011
protein ubiquitination	GO:0016567	70	0.011
nephron development	GO:0072006	3	0.011
retina development in camera type eye	GO:0060041	4	0.011
columnar cuboidal epithelial cell development	GO:0002066	249	0.011
organic substance catabolic process	GO:1901575	308	0.011
regulation of nucleotide metabolic process	GO:0006140	62	0.011
organic cyclic compound catabolic process	GO:1901361	168	0.011
regulation of cellular response to stress	GO:0080135	89	0.010
defense response	GO:0006952	300	0.010
regulation of nucleocytoplasmic transport	GO:0046822	35	0.010
regulation of defense response	GO:0031347	102	0.010
organ growth	GO:0035265	56	0.010
skeletal muscle organ development	GO:0060538	48	0.010
amine metabolic process	GO:0009308	12	0.010
protein palmitoylation	GO:0018345	2	0.010
protein localization to organelle	GO:0033365	82	0.010
antimicrobial humoral response	GO:0019730	99	0.010
renal tubule development	GO:0061326	64	0.010
regulation of actin cytoskeleton organization	GO:0032956	42	0.010
multicellular organismal reproductive behavior	GO:0033057	110	0.010
carbohydrate derivative metabolic process	GO:1901135	217	0.010
regulation of cell size	GO:0008361	63	0.010
extrinsic apoptotic signaling pathway	GO:0097191	1	0.010
signal transduction by phosphorylation	GO:0023014	107	0.010
melanin metabolic process	GO:0006582	47	0.010

CG12042 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.018
disease of cellular proliferation	DOID:14566	0.010
cancer	DOID:162	0.010

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