Drosophila melanogaster

130 known processes

hb (Dmel_CG9786)

hunchback

(Aliases: Hunchback,l(3)85Ah,CG9786,Rg-pbx,Dmel\CG9786,Hb,Rg-bx,hbHLH,HB,R-pbx)

hb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
segmentationGO:00352822070.981
regionalizationGO:00030024160.969
negative regulation of cellular metabolic processGO:00313243820.957
zygotic determination of anterior posterior axis embryoGO:0007354270.920
embryonic axis specificationGO:00005781070.907
motor neuron axon guidanceGO:0008045580.907
axonogenesisGO:00074092900.898
regulation of transcription from rna polymerase ii promoterGO:00063573780.891
negative regulation of nucleic acid templated transcriptionGO:19035072400.863
anterior posterior axis specification embryoGO:00085951030.861
negative regulation of gene expressionGO:00106293870.811
anterior posterior axis specificationGO:00099481090.795
negative regulation of cellular biosynthetic processGO:00313272770.782
taxisGO:00423303040.773
axon guidanceGO:00074112330.770
positive regulation of gene expressionGO:00106282900.764
negative regulation of rna metabolic processGO:00512532510.725
anterior posterior pattern specificationGO:00099521360.705
tripartite regional subdivisionGO:00073511030.692
pole plasm oskar mrna localizationGO:0045451460.685
neuron projection guidanceGO:00974852410.679
oocyte developmentGO:00485991240.671
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.670
axon developmentGO:00615642970.666
central nervous system developmentGO:00074172010.665
cell maturationGO:00484691440.637
positive regulation of rna biosynthetic processGO:19026802660.622
negative regulation of nitrogen compound metabolic processGO:00511722650.612
transcription from rna polymerase ii promoterGO:00063663680.585
neuroblast fate determinationGO:0007400120.572
terminal region determinationGO:0007362250.570
positive regulation of transcription dna templatedGO:00458932660.568
chemotaxisGO:00069352490.541
embryonic pattern specificationGO:00098801740.530
negative regulation of rna biosynthetic processGO:19026792400.517
neuroblast fate commitmentGO:0014017190.509
oocyte anterior posterior axis specificationGO:0007314720.506
positive regulation of nucleic acid templated transcriptionGO:19035082660.505
negative regulation of macromolecule biosynthetic processGO:00105582700.495
developmental maturationGO:00217001720.443
oocyte differentiationGO:00099941450.441
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.435
negative regulation of transcription dna templatedGO:00458922370.433
maternal determination of anterior posterior axis embryoGO:0008358740.424
pole plasm mrna localizationGO:0019094490.395
negative regulation of nucleobase containing compound metabolic processGO:00459342610.386
regulation of multicellular organismal developmentGO:20000264140.361
positive regulation of macromolecule biosynthetic processGO:00105572830.359
pole plasm assemblyGO:0007315610.357
axis specificationGO:00097981670.357
torso signaling pathwayGO:0008293210.346
intracellular mrna localizationGO:0008298660.331
negative regulation of biosynthetic processGO:00098902770.325
chromatin organizationGO:00063252070.320
tube developmentGO:00352952440.317
blastoderm segmentationGO:00073501590.294
multi organism behaviorGO:00517051750.293
Worm
intracellular mrna localization involved in pattern specification processGO:0060810560.291
pole plasm rna localizationGO:0007316520.286
positive regulation of nitrogen compound metabolic processGO:00511733540.269
multicellular organismal reproductive behaviorGO:00330571100.265
Worm
circulatory system developmentGO:0072359820.264
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.253
negative regulation of response to stimulusGO:00485852580.241
germ cell migrationGO:0008354430.230
dendrite morphogenesisGO:00488131990.220
positive regulation of biosynthetic processGO:00098913160.210
antimicrobial humoral responseGO:0019730990.205
embryo development ending in birth or egg hatchingGO:00097921520.200
Worm
establishment or maintenance of cell polarityGO:00071631670.198
regulation of protein metabolic processGO:00512462560.196
regulation of cell proliferationGO:00421271630.190
negative regulation of cell communicationGO:00106482230.182
immune system processGO:00023763470.177
morphogenesis of an epitheliumGO:00020092760.173
cell deathGO:00082192790.172
sex determinationGO:0007530180.168
regulation of nervous system developmentGO:00519602480.167
regulation of response to external stimulusGO:00321011150.165
response to alcoholGO:0097305950.164
oocyte constructionGO:00073081120.161
regulation of response to stressGO:00801342000.158
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.152
positive regulation of response to stimulusGO:00485843230.151
immune responseGO:00069552460.137
cognitionGO:00508901410.136
single organism behaviorGO:00447083910.134
embryonic morphogenesisGO:00485982060.134
oocyte axis specificationGO:00073091080.130
response to external biotic stimulusGO:00432072930.129
regulation of cellular protein metabolic processGO:00322682430.128
cellular response to chemical stimulusGO:00708871990.126
aggressive behaviorGO:0002118630.126
positive regulation of nucleobase containing compound metabolic processGO:00459353320.119
head developmentGO:00603221350.117
rna localizationGO:00064031150.114
gene silencingGO:00164581380.112
epithelial cell developmentGO:00020642740.111
respiratory system developmentGO:00605412130.110
response to abiotic stimulusGO:00096283410.109
cell proliferationGO:00082832990.108
imaginal disc derived appendage developmentGO:00487373990.106
positive regulation of cellular amino acid metabolic processGO:004576400.106
positive regulation of macromolecule metabolic processGO:00106044050.106
tissue morphogenesisGO:00487292970.105
oocyte maturationGO:000155630.104
positive regulation of cellular amine metabolic processGO:003324000.104
regulation of oocyte developmentGO:0060281270.103
digestive system developmentGO:00551231490.101
negative regulation of cell cycleGO:00457861160.100
hindbrain developmentGO:003090220.098
response to oxygen containing compoundGO:19017002000.097
body morphogenesisGO:001017120.097
Worm
neuroblast differentiationGO:0014016290.096
regulation of gene expression epigeneticGO:00400291280.096
multi organism reproductive behaviorGO:00447051210.092
Worm
developmental growthGO:00485892800.091
regulation of localizationGO:00328792750.090
locomotory behaviorGO:00076261760.090
positive regulation of rna metabolic processGO:00512542710.089
gastrulationGO:0007369700.089
morphogenesis of embryonic epitheliumGO:0016331940.087
adult locomotory behaviorGO:0008344760.084
cellular response to oxygen containing compoundGO:1901701790.084
response to organic substanceGO:00100332840.082
epithelial cell migrationGO:00106311480.081
gland developmentGO:00487321910.081
synaptic transmissionGO:00072682880.079
response to other organismGO:00517072930.079
positive regulation of cell communicationGO:00106472500.078
dorsal ventral pattern formationGO:00099531330.076
protein alkylationGO:0008213430.076
appendage morphogenesisGO:00351073970.076
hematopoietic or lymphoid organ developmentGO:0048534570.074
cytoplasm organizationGO:0007028640.071
positive regulation of signal transductionGO:00099672230.070
renal system developmentGO:0072001720.068
chromosome organizationGO:00512763600.067
kidney developmentGO:000182230.066
organic acid metabolic processGO:00060821030.065
cellular ketone metabolic processGO:0042180240.065
carboxylic acid metabolic processGO:0019752920.065
dendrite developmentGO:00163582040.064
regulation of epithelial cell migration open tracheal systemGO:2000274110.064
regulation of immune system processGO:00026821760.064
positive regulation of cell proliferationGO:0008284470.061
cell migrationGO:00164772380.060
regulation of pole plasm oskar mrna localizationGO:0007317270.060
cell fate determinationGO:0001709910.060
negative regulation of signalingGO:00230572190.059
positive regulation of signalingGO:00230562430.059
regulation of humoral immune responseGO:0002920510.059
regulation of cell cycleGO:00517262910.059
forebrain developmentGO:003090020.057
ventral cord developmentGO:0007419160.056
muscle structure developmentGO:00610612240.055
development of primary sexual characteristicsGO:0045137500.055
Worm
regulation of reproductive processGO:2000241540.054
stem cell fate commitmentGO:0048865250.054
somatic stem cell divisionGO:0048103370.053
telencephalon developmentGO:002153720.053
neurological system processGO:00508773580.053
cellular response to endogenous stimulusGO:0071495800.052
stem cell divisionGO:0017145690.052
regulation of cellular component movementGO:0051270420.052
cardiovascular system developmentGO:0072358820.052
brain developmentGO:00074201200.052
regulation of cell developmentGO:00602842150.051
oocyte microtubule cytoskeleton polarizationGO:0008103220.049
germarium derived female germ line cyst encapsulationGO:003070880.048
deathGO:00162652840.048
peptide metabolic processGO:0006518800.048
camera type eye developmentGO:004301040.048
learning or memoryGO:00076111410.048
cell motilityGO:00488702510.048
amide biosynthetic processGO:0043604420.048
ovipositionGO:0018991190.047
Worm
tissue migrationGO:00901301550.045
regulation of cellular amino acid metabolic processGO:000652100.045
cellular component assembly involved in morphogenesisGO:00109271510.044
response to nitrogen compoundGO:1901698900.044
covalent chromatin modificationGO:00165691060.044
imaginal disc derived wing morphogenesisGO:00074763370.044
embryonic development via the syncytial blastodermGO:00017001480.043
reproductive behaviorGO:00190981220.043
Worm
spinal cord developmentGO:002151010.043
digestive tract developmentGO:00485651490.043
small molecule metabolic processGO:00442813050.043
adult behaviorGO:00305341370.042
central nervous system neuron differentiationGO:002195380.042
regulation of immune responseGO:00507761180.042
learningGO:0007612750.042
response to woundingGO:0009611940.041
cellular protein modification processGO:00064644380.041
digestive tract morphogenesisGO:00485461270.040
apoptotic processGO:00069151590.039
neuron fate commitmentGO:0048663500.038
response to endogenous stimulusGO:00097191190.038
imaginal disc derived appendage morphogenesisGO:00351143950.037
regulation of organelle organizationGO:00330431960.037
antimicrobial peptide productionGO:0002775460.037
humoral immune responseGO:00069591170.037
negative regulation of developmental processGO:00510932010.036
response to radiationGO:00093141550.036
appendage developmentGO:00487364010.036
establishment of localization in cellGO:00516494020.035
trunk segmentationGO:003529080.035
organic hydroxy compound metabolic processGO:1901615830.034
regulation of molecular functionGO:00650092170.034
cellular amide metabolic processGO:0043603800.034
negative regulation of signal transductionGO:00099682060.034
positive regulation of cellular protein metabolic processGO:00322701180.034
regulation of cellular amide metabolic processGO:0034248390.033
regulation of chitin based cuticle tanningGO:0007564140.032
regulation of gene silencingGO:0060968630.032
immune system developmentGO:0002520570.032
rhythmic processGO:00485111060.031
head involutionGO:0008258350.031
localization of cellGO:00516742570.031
dendrite guidanceGO:0070983210.031
spermatogenesisGO:00072832000.031
muscle organ developmentGO:00075171270.031
immune effector processGO:0002252980.031
sensory perception of chemical stimulusGO:00076061160.030
regulation of multi organism processGO:00439001310.030
oocyte microtubule cytoskeleton organizationGO:0016325350.030
positive regulation of cellular biosynthetic processGO:00313283160.030
cell divisionGO:00513012480.030
specification of segmental identity trunkGO:003529270.030
defense response to other organismGO:00985422250.030
organonitrogen compound biosynthetic processGO:19015661170.030
regulation of antimicrobial humoral responseGO:0002759500.029
response to biotic stimulusGO:00096072940.029
programmed cell deathGO:00125012570.028
macromolecular complex assemblyGO:00650032560.028
response to decreased oxygen levelsGO:0036293580.028
establishment or maintenance of cytoskeleton polarityGO:0030952440.027
amine metabolic processGO:0009308120.027
phagocytosisGO:00069092150.027
pole plasm protein localizationGO:0007318100.027
chromatin assembly or disassemblyGO:0006333520.027
post embryonic appendage morphogenesisGO:00351203850.027
imaginal disc pattern formationGO:0007447910.027
inter male aggressive behaviorGO:0002121600.027
regulation of production of molecular mediator of immune responseGO:0002700440.026
neuron remodelingGO:0016322290.026
meiotic nuclear divisionGO:00071261510.026
long term memoryGO:0007616620.026
response to organic cyclic compoundGO:0014070890.026
connective tissue developmentGO:006144830.026
epithelial tube morphogenesisGO:0060562880.026
regulation of adult chitin containing cuticle pigmentationGO:0048082130.025
columnar cuboidal epithelial cell differentiationGO:00020652560.025
circadian rhythmGO:00076231050.025
regulation of cell deathGO:00109411730.024
compound eye photoreceptor fate commitmentGO:0001752360.024
antimicrobial peptide biosynthetic processGO:0002777380.024
nuclear divisionGO:00002803320.024
cellular response to organic substanceGO:00713101320.024
organonitrogen compound metabolic processGO:19015643180.023
single organism biosynthetic processGO:00447112060.023
regulation of phosphatase activityGO:001092130.023
stem cell differentiationGO:00488631170.023
exocrine system developmentGO:00352721620.023
neuron recognitionGO:00080381010.023
regulation of cell adhesionGO:0030155270.023
segment specificationGO:0007379330.023
regulation of cellular response to stressGO:0080135890.022
cellular response to decreased oxygen levelsGO:0036294300.022
hemopoiesisGO:0030097460.022
male meiosisGO:0007140520.022
negative regulation of cell cycle phase transitionGO:19019881030.022
sensitizationGO:004696010.021
pigment metabolic processGO:0042440840.021
regulation of epithelial cell proliferationGO:005067840.021
response to temperature stimulusGO:00092661060.020
neuroblast developmentGO:0014019130.020
negative regulation of cellular protein metabolic processGO:0032269850.020
cell activationGO:000177590.020
extracellular structure organizationGO:0043062460.020
kidney epithelium developmentGO:007207330.020
growthGO:00400073590.020
regulation of tube sizeGO:0035150460.020
chemosensory behaviorGO:00076351060.019
wnt signaling pathwayGO:0016055980.019
negative regulation of cell differentiationGO:00455961430.019
regulation of cellular amine metabolic processGO:003323830.019
methylationGO:0032259470.019
regulation of programmed cell deathGO:00430671520.019
ameboidal type cell migrationGO:00016671510.019
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.019
regulation of response to biotic stimulusGO:0002831630.019
regulation of wnt signaling pathwayGO:0030111680.019
regulation of antimicrobial peptide productionGO:0002784440.019
defense responseGO:00069523000.019
regulation of cellular ketone metabolic processGO:001056530.018
proteolysisGO:00065081920.018
defense response to gram negative bacteriumGO:0050829940.018
regulation of apoptotic processGO:00429811300.018
lateral inhibitionGO:00463312060.018
phosphorylationGO:00163102940.018
regulation of cell sizeGO:0008361630.018
embryonic organ developmentGO:0048568500.018
cellular macromolecule localizationGO:00707272200.018
feeding behaviorGO:0007631500.018
protein complex biogenesisGO:00702712010.018
protein complex assemblyGO:00064612000.018
positive regulation of intracellular signal transductionGO:19025331160.017
notch signaling pathwayGO:00072191200.017
syncytial blastoderm mitotic cell cycleGO:0035186210.017
dna integrity checkpointGO:0031570810.017
epithelial cell differentiationGO:00308553220.017
response to fungusGO:0009620500.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.017
positive regulation of cell differentiationGO:0045597640.017
branching morphogenesis of an epithelial tubeGO:0048754450.016
nephron developmentGO:007200630.016
open tracheal system developmentGO:00074242040.016
epithelial cell migration open tracheal systemGO:0007427320.016
neural precursor cell proliferationGO:0061351750.016
response to extracellular stimulusGO:00099911160.016
cellular amino acid metabolic processGO:0006520610.016
single organism intracellular transportGO:19025822070.016
imaginal disc derived female genitalia developmentGO:000748660.016
agingGO:00075681430.016
germarium derived egg chamber formationGO:00072931010.016
protein modification processGO:00362114380.016
cellular amine metabolic processGO:0044106120.016
response to organonitrogen compoundGO:0010243750.016
olfactory behaviorGO:0042048970.016
protein methylationGO:0006479430.015
posterior head segmentationGO:003528960.015
establishment of ommatidial planar polarityGO:0042067490.015
positive regulation of cell migrationGO:003033520.015
instar larval developmentGO:0002168550.015
synaptic target recognitionGO:0008039450.015
blood circulationGO:0008015260.015
negative regulation of growthGO:0045926840.015
negative regulation of multicellular organismal processGO:00512411420.015
male gamete generationGO:00482322010.015
larval developmentGO:00021641040.015
Worm
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.015
regulation of epithelial cell migrationGO:0010632120.014
mitotic nuclear divisionGO:00070672130.014
response to acid chemicalGO:0001101250.014
regulation of cell motilityGO:2000145230.014
cellular lipid metabolic processGO:0044255830.014
intracellular signal transductionGO:00355563000.014
oocyte dorsal ventral axis specificationGO:0007310340.014
cell fate specificationGO:0001708710.014
female germ line cyst encapsulationGO:004813980.014
immune response regulating signaling pathwayGO:000276420.014
peptide biosynthetic processGO:0043043420.014
germ line cyst encapsulationGO:004813880.014
establishment of tissue polarityGO:0007164870.014
dorsal closureGO:0007391790.014
positive regulation of immune system processGO:0002684680.014
response to hormoneGO:0009725450.013
histone methylationGO:0016571400.013
regulation of membrane depolarizationGO:000325410.013
positive regulation of molecular functionGO:00440931360.013
response to hypoxiaGO:0001666530.013
morphogenesis of a branching epitheliumGO:0061138450.013
axon choice point recognitionGO:0016198260.013
regulation of neurogenesisGO:00507671580.013
regulation of locomotionGO:0040012420.013
molting cycleGO:0042303560.013
urogenital system developmentGO:0001655720.013
establishment or maintenance of apical basal cell polarityGO:0035088340.013
heart developmentGO:0007507820.013
membrane depolarizationGO:005189940.013
wound healingGO:0042060750.012
catabolic processGO:00090564090.012
nitrogen compound transportGO:0071705850.012
sex differentiationGO:0007548810.012
Worm
spiracle morphogenesis open tracheal systemGO:0035277220.012
positive regulation of antimicrobial peptide productionGO:0002225280.012
multicellular organismal agingGO:00102591400.012
single organism cellular localizationGO:19025801800.012
maintenance of protein location in cellGO:0032507260.012
regulation of protein modification processGO:00313991120.012
developmental cell growthGO:0048588520.012
mesenchymal cell developmentGO:001403110.012
regulation of defense responseGO:00313471020.012
negative regulation of defense responseGO:0031348350.012
regulation of growthGO:00400082330.012
nephron epithelium developmentGO:007200930.012
posttranscriptional regulation of gene expressionGO:00106081450.012
positive regulation of cell deathGO:0010942690.012
chromatin modificationGO:00165681470.012
positive regulation of apoptotic processGO:0043065470.012
negative regulation of cell cell adhesionGO:002240880.012
positive regulation of cell motilityGO:200014730.011
wing disc morphogenesisGO:00074723440.011
mesenchymal cell differentiationGO:004876210.011
kidney morphogenesisGO:006099330.011
cell agingGO:000756920.011
response to oxygen levelsGO:0070482590.011
nucleoside phosphate metabolic processGO:00067531620.011
nephron tubule developmentGO:007208030.011
neuroblast fate specificationGO:001401820.011
neuron maturationGO:0042551310.011
regulation of antimicrobial peptide biosynthetic processGO:0002805380.011
neuroblast divisionGO:0055057350.011
intracellular transportGO:00469072280.011
multi multicellular organism processGO:00447061230.011
Worm
response to bacteriumGO:00096171980.011
regulation of dna templated transcription in response to stressGO:004362040.011
negative regulation of gene expression epigeneticGO:0045814770.011
developmental programmed cell deathGO:00106231380.011
determination of adult lifespanGO:00083401370.011
border follicle cell migrationGO:00072981130.010
innate immune responseGO:00450871440.010
cellular response to lipopolysaccharideGO:007122230.010
negative regulation of mitotic cell cycleGO:00459301090.010
response to reactive oxygen speciesGO:0000302240.010
skin developmentGO:0043588650.010
cardioblast cell fate commitmentGO:0042684140.010
asymmetric cell divisionGO:0008356370.010
positive regulation of multi organism processGO:0043902400.010
regulation of chromatin organizationGO:1902275320.010
cellular response to lipidGO:0071396200.010

hb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.011
cancerDOID:16200.011