Drosophila melanogaster

0 known processes

ppk21 (Dmel_CG12048)

pickpocket 21

(Aliases: CG12048,PPK21,Dmel\CG12048)

ppk21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of chemical stimulusGO:0009593930.085
detection of stimulusGO:00516061560.085
Fly
single organism behaviorGO:00447083910.082
Fly
detection of stimulus involved in sensory perceptionGO:0050906920.081
Fly
sensory perceptionGO:00076001960.077
Fly
regulation of transcription from rna polymerase ii promoterGO:00063573780.065
transcription from rna polymerase ii promoterGO:00063663680.061
sensory perception of chemical stimulusGO:00076061160.060
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.052
forebrain developmentGO:003090020.051
regionalizationGO:00030024160.048
taxisGO:00423303040.047
regulation of multicellular organismal developmentGO:20000264140.044
cell migrationGO:00164772380.044
Rat
tissue morphogenesisGO:00487292970.043
Rat
negative regulation of cellular metabolic processGO:00313243820.043
body morphogenesisGO:001017120.043
axon guidanceGO:00074112330.040
positive regulation of rna biosynthetic processGO:19026802660.039
positive regulation of transcription dna templatedGO:00458932660.039
localization of cellGO:00516742570.038
Rat
compound eye developmentGO:00487493070.037
axonogenesisGO:00074092900.037
cell motilityGO:00488702510.036
Rat
neurological system processGO:00508773580.036
Fly
organonitrogen compound metabolic processGO:19015643180.036
regulation of anatomical structure morphogenesisGO:00226032420.036
tube morphogenesisGO:00352391910.036
immune responseGO:00069552460.036
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.036
small molecule metabolic processGO:00442813050.036
response to abiotic stimulusGO:00096283410.036
Rat Fly
positive regulation of nucleic acid templated transcriptionGO:19035082660.036
lateral inhibitionGO:00463312060.035
negative regulation of macromolecule biosynthetic processGO:00105582700.035
positive regulation of gene expressionGO:00106282900.035
morphogenesis of an epitheliumGO:00020092760.035
Rat
positive regulation of biosynthetic processGO:00098913160.034
negative regulation of gene expressionGO:00106293870.034
detection of chemical stimulus involved in sensory perceptionGO:0050907750.033
negative regulation of nitrogen compound metabolic processGO:00511722650.033
central nervous system developmentGO:00074172010.033
positive regulation of cellular biosynthetic processGO:00313283160.032
columnar cuboidal epithelial cell differentiationGO:00020652560.032
eye developmentGO:00016543230.032
epithelial cell differentiationGO:00308553220.032
positive regulation of macromolecule metabolic processGO:00106044050.032
sensory organ morphogenesisGO:00905962600.031
organelle fissionGO:00482853400.031
regulation of nervous system developmentGO:00519602480.030
catabolic processGO:00090564090.030
neuron projection guidanceGO:00974852410.030
head developmentGO:00603221350.030
compound eye morphogenesisGO:00017452490.030
positive regulation of nitrogen compound metabolic processGO:00511733540.029
negative regulation of rna metabolic processGO:00512532510.029
locomotory behaviorGO:00076261760.029
Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.029
organic substance catabolic processGO:19015753080.028
reproductive behaviorGO:00190981220.028
Fly
negative regulation of rna biosynthetic processGO:19026792400.028
photoreceptor cell differentiationGO:00465301700.027
negative regulation of cellular biosynthetic processGO:00313272770.027
response to organic substanceGO:00100332840.027
Fly
compound eye photoreceptor cell differentiationGO:00017511400.027
positive regulation of macromolecule biosynthetic processGO:00105572830.026
negative regulation of nucleic acid templated transcriptionGO:19035072400.026
eye morphogenesisGO:00485922600.026
cell proliferationGO:00082832990.026
hindbrain developmentGO:003090220.026
chemotaxisGO:00069352490.026
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.025
negative regulation of transcription dna templatedGO:00458922370.025
telencephalon developmentGO:002153720.025
positive regulation of response to stimulusGO:00485843230.025
regulation of cell differentiationGO:00455953020.025
protein modification processGO:00362114380.024
response to biotic stimulusGO:00096072940.024
cell cell signaling involved in cell fate commitmentGO:00451682100.024
cell deathGO:00082192790.024
response to external biotic stimulusGO:00432072930.024
eye photoreceptor cell differentiationGO:00017541450.024
regulation of cell cycleGO:00517262910.024
negative regulation of response to stimulusGO:00485852580.024
Fly
defense responseGO:00069523000.024
adult behaviorGO:00305341370.024
immune system processGO:00023763470.023
cellular protein modification processGO:00064644380.023
appendage morphogenesisGO:00351073970.023
tube developmentGO:00352952440.023
mating behaviorGO:00076171060.023
Fly
response to other organismGO:00517072930.023
appendage developmentGO:00487364010.023
positive regulation of cell communicationGO:00106472500.023
humoral immune responseGO:00069591170.023
multi organism behaviorGO:00517051750.023
Fly
salivary gland morphogenesisGO:00074351450.023
cellular catabolic processGO:00442483720.023
negative regulation of biosynthetic processGO:00098902770.023
proteolysisGO:00065081920.023
programmed cell deathGO:00125012570.022
endocytosisGO:00068973100.022
camera type eye developmentGO:004301040.022
matingGO:00076181200.022
Fly
organelle assemblyGO:00709251980.022
carboxylic acid metabolic processGO:0019752920.022
sensory perception of smellGO:0007608800.022
oxoacid metabolic processGO:00434361030.022
positive regulation of rna metabolic processGO:00512542710.022
regulation of localizationGO:00328792750.022
Rat
organic acid metabolic processGO:00060821030.022
regulation of cell morphogenesisGO:00226041630.022
organic substance transportGO:00717022570.022
establishment of localization in cellGO:00516494020.022
salt aversionGO:003519930.021
Fly
developmental growthGO:00485892800.021
blastoderm segmentationGO:00073501590.021
ameboidal type cell migrationGO:00016671510.021
open tracheal system developmentGO:00074242040.021
Fly
macromolecular complex assemblyGO:00650032560.020
salivary gland developmentGO:00074311620.020
regulation of embryonic developmentGO:0045995680.020
multi organism reproductive behaviorGO:00447051210.020
Fly
single organism catabolic processGO:00447122280.020
positive regulation of signalingGO:00230562430.020
imaginal disc derived wing morphogenesisGO:00074763370.020
phosphorylationGO:00163102940.020
nuclear divisionGO:00002803320.020
regulation of anatomical structure sizeGO:00900661630.020
cellular response to dna damage stimulusGO:00069742230.020
spinal cord developmentGO:002151010.020
peptide metabolic processGO:0006518800.019
olfactory behaviorGO:0042048970.019
exocrine system developmentGO:00352721620.019
phagocytosisGO:00069092150.019
negative regulation of nucleobase containing compound metabolic processGO:00459342610.019
vesicle mediated transportGO:00161923810.019
brain developmentGO:00074201200.019
regulation of mitotic cell cycleGO:00073461900.019
homeostatic processGO:00425921990.019
Human
positive regulation of signal transductionGO:00099672230.019
growthGO:00400073590.019
deathGO:00162652840.019
epithelial cell developmentGO:00020642740.019
aromatic compound catabolic processGO:00194391660.018
regulation of multi organism processGO:00439001310.018
kidney developmentGO:000182230.018
innate immune responseGO:00450871440.018
regulation of cellular amine metabolic processGO:003323830.018
imaginal disc derived appendage morphogenesisGO:00351143950.018
negative regulation of developmental processGO:00510932010.018
imaginal disc derived appendage developmentGO:00487373990.018
gland morphogenesisGO:00226121450.018
response to oxygen containing compoundGO:19017002000.018
Fly
organonitrogen compound biosynthetic processGO:19015661170.018
protein complex biogenesisGO:00702712010.018
sensory perception of salty tasteGO:005091430.018
Fly
response to organophosphorusGO:004668320.018
negative regulation of signalingGO:00230572190.018
post embryonic appendage morphogenesisGO:00351203850.018
cell divisionGO:00513012480.017
cellular amino acid metabolic processGO:0006520610.017
response to woundingGO:0009611940.017
Rat
wing disc morphogenesisGO:00074723440.017
protein heterooligomerizationGO:005129140.017
immune response regulating signaling pathwayGO:000276420.017
actin cytoskeleton organizationGO:00300362060.017
single organism biosynthetic processGO:00447112060.017
regulation of cellular ketone metabolic processGO:001056530.017
carbohydrate derivative metabolic processGO:19011352170.017
mesenchymal cell differentiationGO:004876210.017
columnar cuboidal epithelial cell developmentGO:00020662490.017
regulation of catalytic activityGO:00507901850.017
response to lipopolysaccharideGO:003249640.017
regulation of molecular functionGO:00650092170.017
regulation of immune responseGO:00507761180.017
protein complex assemblyGO:00064612000.017
embryonic pattern specificationGO:00098801740.017
regulation of response to stressGO:00801342000.017
multicellular organismal reproductive behaviorGO:00330571100.017
Fly
intracellular signal transductionGO:00355563000.017
antimicrobial humoral responseGO:0019730990.017
respiratory system developmentGO:00605412130.017
Fly
protein localizationGO:00081042840.017
connective tissue developmentGO:006144830.017
ovarian follicle cell developmentGO:00307072480.017
synaptic transmissionGO:00072682880.017
Fly
organophosphate metabolic processGO:00196371950.017
negative regulation of signal transductionGO:00099682060.017
regulation of organelle organizationGO:00330431960.016
regulation of cellular amino acid metabolic processGO:000652100.016
retina development in camera type eyeGO:006004140.016
nucleotide metabolic processGO:00091171610.016
immune response activating signal transductionGO:000275720.016
defense response to other organismGO:00985422250.016
organonitrogen compound catabolic processGO:19015651280.016
chromosome organizationGO:00512763600.016
establishment of tissue polarityGO:0007164870.016
dendrite morphogenesisGO:00488131990.016
embryonic morphogenesisGO:00485982060.016
purine nucleotide metabolic processGO:00061631460.016
regulation of programmed cell deathGO:00430671520.016
cellular response to chemical stimulusGO:00708871990.016
Fly
heterocycle catabolic processGO:00467001660.016
spindle organizationGO:00070512530.016
anterior posterior pattern specificationGO:00099521360.016
negative regulation of cell communicationGO:00106482230.016
cellular component assembly involved in morphogenesisGO:00109271510.016
amine metabolic processGO:0009308120.016
multi multicellular organism processGO:00447061230.016
Fly
protein hydroxylationGO:001812610.016
regulation of phosphorus metabolic processGO:00511742100.016
mitotic nuclear divisionGO:00070672130.016
ribonucleotide metabolic processGO:00092591450.016
organic cyclic compound catabolic processGO:19013611680.016
spermatogenesisGO:00072832000.016
regulation of growthGO:00400082330.016
gland developmentGO:00487321910.015
steroid catabolic processGO:000670610.015
hormone catabolic processGO:004244730.015
positive regulation of phosphorus metabolic processGO:00105621390.015
ion transportGO:00068111450.015
Human Rat Fly
response to bacteriumGO:00096171980.015
single organism intracellular transportGO:19025822070.015
mesenchymal cell developmentGO:001403110.015
wound healingGO:0042060750.015
Rat
ras protein signal transductionGO:0007265880.015
drinking behaviorGO:004275620.015
Fly
intracellular transportGO:00469072280.015
regulation of developmental growthGO:00486381740.015
xenobiotic catabolic processGO:004217810.015
regulation of protein metabolic processGO:00512462560.015
positive regulation of cell migrationGO:003033520.015
nephron developmentGO:007200630.015
purine ribonucleotide metabolic processGO:00091501450.015
adult locomotory behaviorGO:0008344760.015
chromosome segregationGO:00070591570.015
endomembrane system organizationGO:00102561190.015
dendrite developmentGO:00163582040.015
neural precursor cell proliferationGO:0061351750.015
regulation of immune system processGO:00026821760.015
nucleobase containing small molecule metabolic processGO:00550861740.015
negative regulation of cell differentiationGO:00455961430.015
camera type eye morphogenesisGO:004859320.014
macromolecule catabolic processGO:00090571610.014
regulation of synapse structure and activityGO:00508031280.014
Fly
regulation of immune effector processGO:0002697520.014
actin filament based processGO:00300292200.014
wnt signaling pathwayGO:0016055980.014
regulation of response to external stimulusGO:00321011150.014
stem cell differentiationGO:00488631170.014
regulation of cell cycle processGO:00105641810.014
developmental maturationGO:00217001720.014
regulation of phosphate metabolic processGO:00192202100.014
determination of adult lifespanGO:00083401370.014
regulation of intracellular signal transductionGO:19025312360.014
negative regulation of multicellular organismal processGO:00512411420.014
axon developmentGO:00615642970.014
regulation of cell deathGO:00109411730.014
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.014
ion transmembrane transportGO:00342201220.014
Human Rat Fly
immune effector processGO:0002252980.014
positive regulation of cell motilityGO:200014730.014
single organism cellular localizationGO:19025801800.014
monocarboxylic acid transportGO:001571830.014
establishment or maintenance of cell polarityGO:00071631670.014
neuron fate commitmentGO:0048663500.014
digestive tract developmentGO:00485651490.014
response to monosaccharideGO:003428440.014
regulation of cell proliferationGO:00421271630.014
chemosensory behaviorGO:00076351060.014
regulation of cell developmentGO:00602842150.014
male gamete generationGO:00482322010.014
detection of external stimulusGO:0009581660.013
Fly
behavioral response to painGO:004826630.013
Fly
regulation of apoptotic processGO:00429811300.013
positive regulation of molecular functionGO:00440931360.013
regulation of transportGO:00510491810.013
Rat
regulation of cellular protein metabolic processGO:00322682430.013
epithelial tube morphogenesisGO:0060562880.013
defense response to bacteriumGO:00427421780.013
protein transportGO:00150311550.013
dorsal ventral axis specificationGO:0009950660.013
ribose phosphate metabolic processGO:00196931450.013
purine containing compound metabolic processGO:00725211550.013
regulation of cellular component biogenesisGO:00440872010.013
locomotor rhythmGO:0045475560.013
sensory perception of painGO:001923340.013
Fly
compound eye photoreceptor developmentGO:0042051780.013
regulation of notch signaling pathwayGO:00085931000.013
cellular amide metabolic processGO:0043603800.013
digestive tract morphogenesisGO:00485461270.013
positive regulation of phosphate metabolic processGO:00459371390.013
developmental programmed cell deathGO:00106231380.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
regulation of cell shapeGO:00083601130.013
muscle structure developmentGO:00610612240.013
actin filament organizationGO:00070151260.013
establishment of planar polarityGO:0001736870.013
meiotic cell cycleGO:00513211710.013
mitotic spindle organizationGO:00070522200.013
positive regulation of catalytic activityGO:00430851180.013
cellular macromolecular complex assemblyGO:00346221530.013
regulation of response to biotic stimulusGO:0002831630.013
cellular ketone metabolic processGO:0042180240.013
cellular amine metabolic processGO:0044106120.013
stem cell developmentGO:0048864790.013
axis specificationGO:00097981670.013
dorsal ventral pattern formationGO:00099531330.013
rhythmic behaviorGO:0007622760.012
melanization defense responseGO:0035006450.012
segmentationGO:00352822070.012
cellular macromolecule localizationGO:00707272200.012
multicellular organismal agingGO:00102591400.012
antimicrobial peptide productionGO:0002775460.012
regulation of neurogenesisGO:00507671580.012
cation transportGO:00068121100.012
Human Rat Fly
phenol containing compound metabolic processGO:0018958570.012
cellular nitrogen compound catabolic processGO:00442701650.012
cell maturationGO:00484691440.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
response to alcoholGO:0097305950.012
regulation of epithelial cell differentiationGO:003085640.012
chorion containing eggshell formationGO:00073041050.012
pigment metabolic processGO:0042440840.012
secondary metabolic processGO:0019748750.012
regulation of hydrolase activityGO:0051336970.012
inter male aggressive behaviorGO:0002121600.012
Fly
apoptotic processGO:00069151590.012
response to hexoseGO:000974630.012
rna localizationGO:00064031150.012
compound eye photoreceptor fate commitmentGO:0001752360.012
small gtpase mediated signal transductionGO:0007264880.012
establishment of protein localizationGO:00451841630.012
activation of innate immune responseGO:000221840.012
regulation of defense responseGO:00313471020.012
golgi organizationGO:0007030660.012
cell fate determinationGO:0001709910.012
chemical homeostasisGO:0048878920.012
Human
benzene containing compound metabolic processGO:004253730.012
regulation of production of molecular mediator of immune responseGO:0002700440.012
digestive system developmentGO:00551231490.012
positive regulation of multicellular organismal processGO:00512401430.012
dna metabolic processGO:00062592270.012
morphogenesis of a polarized epitheliumGO:0001738930.012
microtubule based movementGO:0007018510.012
defense response to gram negative bacteriumGO:0050829940.012
cellular response to water stimulusGO:007146220.012
Fly
gene silencingGO:00164581380.012
cellular response to ethanolGO:007136140.012
wound healing spreading of epidermal cellsGO:003531310.012
Rat
epiboly involved in wound healingGO:009050520.012
Rat
meiotic cell cycle processGO:19030461320.012
nucleoside phosphate metabolic processGO:00067531620.012
chaeta developmentGO:0022416970.012
pattern recognition receptor signaling pathwayGO:000222120.012
regulation of synapse organizationGO:00508071100.012
hematopoietic progenitor cell differentiationGO:000224410.011
transmembrane transportGO:00550851390.011
Human Rat Fly
photoreceptor cell fate commitmentGO:0046552410.011
androgen metabolic processGO:000820910.011
cellular macromolecule catabolic processGO:00442651360.011
regulation of synapse assemblyGO:0051963940.011
cellular response to carbohydrate stimulusGO:007132240.011
photoreceptor cell developmentGO:0042461960.011
acetate ester metabolic processGO:190061920.011
epibolyGO:009050420.011
Rat
regulation of cellular localizationGO:00603411360.011
secretionGO:00469031090.011
vitamin metabolic processGO:000676620.011
peripheral nervous system developmentGO:0007422520.011
regulation of humoral immune responseGO:0002920510.011
l amino acid importGO:004309220.011
microtubule based transportGO:0010970420.011
nephron tubule developmentGO:007208030.011
circadian behaviorGO:0048512760.011
cellular response to organic substanceGO:00713101320.011
agingGO:00075681430.011
regulation of antimicrobial humoral responseGO:0002759500.011
cuticle developmentGO:0042335860.011
response to painGO:004826530.011
Fly
male mating behaviorGO:0060179700.011
Fly
leg disc developmentGO:0035218920.011
secretion by cellGO:00329401010.011
limb developmentGO:006017310.011
positive regulation of developmental processGO:00510941430.011
regulation of innate immune responseGO:0045088710.011
chromatin organizationGO:00063252070.011
ethanolamine containing compound metabolic processGO:004243940.011
neuropeptide signaling pathwayGO:0007218450.011
anatomical structure homeostasisGO:0060249970.011
nephron epithelium developmentGO:007200930.011
production of molecular mediator of immune responseGO:0002440460.011
regulation of phosphorylationGO:00423251470.011
regulation of epithelial cell proliferationGO:005067840.011
negative regulation of cell cycle processGO:00109481090.011
embryonic development via the syncytial blastodermGO:00017001480.011
regulation of gene expression epigeneticGO:00400291280.011
cellular protein localizationGO:00346131600.011
nucleobase containing compound catabolic processGO:00346551650.011
g protein coupled receptor signaling pathwayGO:00071861360.011
regulation of cellular amide metabolic processGO:0034248390.011
negative regulation of nervous system developmentGO:0051961920.011
synaptic growth at neuromuscular junctionGO:00511241190.011
estrogen metabolic processGO:000821010.010
metal ion transportGO:0030001740.010
Human Rat Fly
response to radiationGO:00093141550.010
kidney epithelium developmentGO:007207330.010
peptidyl amino acid modificationGO:00181931050.010
regulation of catabolic processGO:00098941700.010
cellular response to molecule of bacterial originGO:007121930.010
response to organic cyclic compoundGO:0014070890.010
rna processingGO:00063961470.010
purine ribonucleoside catabolic processGO:00461301120.010
response to endogenous stimulusGO:00097191190.010
posttranscriptional regulation of gene expressionGO:00106081450.010
cholesterol homeostasisGO:004263230.010
tripartite regional subdivisionGO:00073511030.010
cellular homeostasisGO:0019725800.010
response to glucoseGO:000974920.010
cellular response to biotic stimulusGO:007121640.010
polyol biosynthetic processGO:004617330.010
regulation of antimicrobial peptide biosynthetic processGO:0002805380.010
amide biosynthetic processGO:0043604420.010

ppk21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
Human
kidney diseaseDOID:55700.019
Human
urinary system diseaseDOID:1800.019
Human
renal tubular transport diseaseDOID:44700.019
Human
cardiovascular system diseaseDOID:128700.018
nervous system diseaseDOID:86300.018
musculoskeletal system diseaseDOID:1700.016
vascular diseaseDOID:17800.016
hypertensionDOID:1076300.016
artery diseaseDOID:005082800.016
inherited metabolic disorderDOID:65500.015
disease of metabolismDOID:001466700.015
respiratory system diseaseDOID:157900.015
Human
disease of cellular proliferationDOID:1456600.013
bronchial diseaseDOID:117600.013
Human
lower respiratory tract diseaseDOID:005016100.013
Human
bronchiectasisDOID:956300.013
Human
liddle syndromeDOID:005047700.011
Human
connective tissue diseaseDOID:6500.010
bone diseaseDOID:008000100.010