IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Dyb (Dmel_CG8529)

Dystrobrevin-like

(Aliases: Dmel\CG8529,DmDYB,CG8529)

FLYBASE: FBgn0033739
Entrez: 36362
UniProtKB: A8DYB7
UniProtKB: A1Z904
UniProtKB: E2QCB7
UniProtKB: Q0E9B2
UniProtKB: A1Z907
UniProtKB: A1Z906

Process Predictions
Disease Predictions

Dyb biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
appendage development	GO:0048736	401	0.160
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.143
single organism intracellular transport	GO:1902582	207	0.085
cyclic purine nucleotide metabolic process	GO:0052652	25	0.085
intracellular signal transduction	GO:0035556	300	0.082
establishment of localization in cell	GO:0051649	402	0.075
cyclic nucleotide metabolic process	GO:0009187	28	0.072
growth	GO:0040007	359	0.070
imaginal disc derived appendage development	GO:0048737	399	0.070
negative regulation of cellular metabolic process	GO:0031324	382	0.069
regulation of intracellular signal transduction	GO:1902531	236	0.066
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.066
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.065
post embryonic appendage morphogenesis	GO:0035120	385	0.063
mitotic nuclear division	GO:0007067	213	0.062
organelle localization	GO:0051640	148	0.060
cyclic nucleotide biosynthetic process	GO:0009190	25	0.060
central nervous system development	GO:0007417	201	0.059
regulation of phosphorus metabolic process	GO:0051174	210	0.058
chromosome organization	GO:0051276	360	0.058
cellular protein modification process	GO:0006464	438	0.058
protein modification process	GO:0036211	438	0.056
appendage morphogenesis	GO:0035107	397	0.056
positive regulation of cell communication	GO:0010647	250	0.052
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.051
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.051
negative regulation of response to stimulus	GO:0048585	258	0.050
negative regulation of biosynthetic process	GO:0009890	277	0.050
nucleotide metabolic process	GO:0009117	161	0.049
phosphorylation	GO:0016310	294	0.049
regulation of catalytic activity	GO:0050790	185	0.048
single organism behavior	GO:0044708	391	0.048
positive regulation of phosphate metabolic process	GO:0045937	139	0.046
positive regulation of response to stimulus	GO:0048584	323	0.046
positive regulation of signaling	GO:0023056	243	0.045
developmental growth	GO:0048589	280	0.045
regulation of protein metabolic process	GO:0051246	256	0.045
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.044
tissue morphogenesis	GO:0048729	297	0.043
ras protein signal transduction	GO:0007265	88	0.043
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.042
negative regulation of rna metabolic process	GO:0051253	251	0.041
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.041
positive regulation of signal transduction	GO:0009967	223	0.040
regulation of molecular function	GO:0065009	217	0.040
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.040
organelle fission	GO:0048285	340	0.040
regulation of phosphate metabolic process	GO:0019220	210	0.039
protein phosphorylation	GO:0006468	169	0.039
wing disc morphogenesis	GO:0007472	344	0.038
regulation of cell cycle	GO:0051726	291	0.038
guanosine containing compound catabolic process	GO:1901069	74	0.038
imaginal disc derived wing morphogenesis	GO:0007476	337	0.038
ribonucleotide metabolic process	GO:0009259	145	0.038
negative regulation of transcription dna templated	GO:0045892	237	0.038
dna metabolic process	GO:0006259	227	0.038
digestive tract development	GO:0048565	149	0.038
single organism cellular localization	GO:1902580	180	0.037
protein transport	GO:0015031	155	0.037
negative regulation of signal transduction	GO:0009968	206	0.037
negative regulation of signaling	GO:0023057	219	0.037
negative regulation of cell communication	GO:0010648	223	0.037
organophosphate metabolic process	GO:0019637	195	0.037
cell proliferation	GO:0008283	299	0.036
vesicle mediated transport	GO:0016192	381	0.036
purine nucleotide metabolic process	GO:0006163	146	0.036
g protein coupled receptor signaling pathway	GO:0007186	136	0.036
negative regulation of cellular biosynthetic process	GO:0031327	277	0.036
regulation of localization	GO:0032879	275	0.035
establishment of protein localization	GO:0045184	163	0.035
organonitrogen compound metabolic process	GO:1901564	318	0.035
morphogenesis of an epithelium	GO:0002009	276	0.035
embryonic morphogenesis	GO:0048598	206	0.035
nucleobase containing small molecule metabolic process	GO:0055086	174	0.034
nucleoside phosphate metabolic process	GO:0006753	162	0.034
immune system process	GO:0002376	347	0.034
negative regulation of rna biosynthetic process	GO:1902679	240	0.034
dna conformation change	GO:0071103	105	0.034
intracellular transport	GO:0046907	228	0.033
negative regulation of gene expression	GO:0010629	387	0.033
protein localization	GO:0008104	284	0.032
axon development	GO:0061564	297	0.032
transcription from rna polymerase ii promoter	GO:0006366	368	0.032
regulation of cell morphogenesis	GO:0022604	163	0.032
cell motility	GO:0048870	251	0.031
cellular nitrogen compound catabolic process	GO:0044270	165	0.031
digestive system development	GO:0055123	149	0.030
regulation of cellular protein metabolic process	GO:0032268	243	0.030
regulation of growth	GO:0040008	233	0.030
locomotory behavior	GO:0007626	176	0.030
regulation of mapk cascade	GO:0043408	92	0.030
ribose phosphate metabolic process	GO:0019693	145	0.029
digestive tract morphogenesis	GO:0048546	127	0.029
regulation of purine nucleotide metabolic process	GO:1900542	62	0.029
regulation of cellular ketone metabolic process	GO:0010565	3	0.029
purine ribonucleotide metabolic process	GO:0009150	145	0.029
localization of cell	GO:0051674	257	0.029
regulation of cell cycle process	GO:0010564	181	0.029
innate immune response	GO:0045087	144	0.029
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.029
organonitrogen compound biosynthetic process	GO:1901566	117	0.029
positive regulation of nucleotide metabolic process	GO:0045981	55	0.029
small gtpase mediated signal transduction	GO:0007264	88	0.029
camp biosynthetic process	GO:0006171	17	0.028
dna packaging	GO:0006323	91	0.028
positive regulation of phosphorus metabolic process	GO:0010562	139	0.027
positive regulation of cellular protein metabolic process	GO:0032270	118	0.027
centrosome organization	GO:0051297	163	0.027
regulation of anatomical structure morphogenesis	GO:0022603	242	0.027
organic substance transport	GO:0071702	257	0.026
cellular response to endogenous stimulus	GO:0071495	80	0.026
carbohydrate derivative metabolic process	GO:1901135	217	0.026
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.025
body morphogenesis	GO:0010171	2	0.025
response to organic substance	GO:0010033	284	0.025
tube morphogenesis	GO:0035239	191	0.025
regulation of organelle organization	GO:0033043	196	0.025
forebrain development	GO:0030900	2	0.025
regulation of nucleotide metabolic process	GO:0006140	62	0.025
positive regulation of intracellular signal transduction	GO:1902533	116	0.025
tube development	GO:0035295	244	0.025
positive regulation of macromolecule metabolic process	GO:0010604	405	0.024
chromatin assembly or disassembly	GO:0006333	52	0.024
regulation of developmental growth	GO:0048638	174	0.024
synaptic transmission	GO:0007268	288	0.024
ribose phosphate biosynthetic process	GO:0046390	28	0.023
purine ribonucleotide biosynthetic process	GO:0009152	28	0.023
ribonucleotide biosynthetic process	GO:0009260	28	0.023
regulation of cellular catabolic process	GO:0031329	157	0.022
regulation of neuron differentiation	GO:0045664	103	0.022
response to nutrient levels	GO:0031667	114	0.022
immune response regulating signaling pathway	GO:0002764	2	0.021
regulation of ras protein signal transduction	GO:0046578	93	0.021
microtubule based movement	GO:0007018	51	0.021
single organism biosynthetic process	GO:0044711	206	0.021
positive regulation of protein metabolic process	GO:0051247	128	0.021
peptidyl amino acid modification	GO:0018193	105	0.021
protein complex assembly	GO:0006461	200	0.021
chemotaxis	GO:0006935	249	0.021
regulation of cell shape	GO:0008360	113	0.021
actin filament organization	GO:0007015	126	0.021
cellular macromolecule localization	GO:0070727	220	0.021
cellular response to chemical stimulus	GO:0070887	199	0.021
response to endogenous stimulus	GO:0009719	119	0.020
regulation of multicellular organismal development	GO:2000026	414	0.020
purine containing compound metabolic process	GO:0072521	155	0.020
neurological system process	GO:0050877	358	0.020
nucleoside phosphate biosynthetic process	GO:1901293	34	0.020
response to oxygen containing compound	GO:1901700	200	0.020
leg disc development	GO:0035218	92	0.020
response to starvation	GO:0042594	97	0.020
posttranscriptional regulation of gene expression	GO:0010608	145	0.020
muscle organ development	GO:0007517	127	0.019
immune response	GO:0006955	246	0.019
single organism membrane organization	GO:0044802	93	0.019
regulation of transport	GO:0051049	181	0.019
positive regulation of cellular catabolic process	GO:0031331	95	0.019
positive regulation of rna biosynthetic process	GO:1902680	266	0.019
regulation of cellular amino acid metabolic process	GO:0006521	0	0.019
protein modification by small protein conjugation or removal	GO:0070647	106	0.019
positive regulation of catalytic activity	GO:0043085	118	0.019
nucleotide biosynthetic process	GO:0009165	34	0.019
positive regulation of gene expression	GO:0010628	290	0.019
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.019
regulation of phosphorylation	GO:0042325	147	0.018
regulation of response to stress	GO:0080134	200	0.018
nuclear division	GO:0000280	332	0.018
response to external biotic stimulus	GO:0043207	293	0.018
secretion by cell	GO:0032940	101	0.018
negative regulation of intracellular signal transduction	GO:1902532	57	0.018
response to other organism	GO:0051707	293	0.018
compound eye development	GO:0048749	307	0.018
centrosome cycle	GO:0007098	137	0.018
sensory organ morphogenesis	GO:0090596	260	0.018
small molecule metabolic process	GO:0044281	305	0.018
microtubule based transport	GO:0010970	42	0.018
epithelial cell differentiation	GO:0030855	322	0.018
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.018
organophosphate biosynthetic process	GO:0090407	46	0.018
erbb signaling pathway	GO:0038127	58	0.018
cell death	GO:0008219	279	0.018
positive regulation of molecular function	GO:0044093	136	0.018
organic cyclic compound catabolic process	GO:1901361	168	0.017
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.017
hindbrain development	GO:0030902	2	0.017
cellular protein localization	GO:0034613	160	0.017
response to alcohol	GO:0097305	95	0.017
regulation of cellular localization	GO:0060341	136	0.017
chromatin organization	GO:0006325	207	0.017
guanosine containing compound metabolic process	GO:1901068	74	0.017
regulation of programmed cell death	GO:0043067	152	0.017
signal transduction by phosphorylation	GO:0023014	107	0.017
actin cytoskeleton organization	GO:0030036	206	0.017
protein localization to organelle	GO:0033365	82	0.017
regulation of cellular amine metabolic process	GO:0033238	3	0.017
positive regulation of transcription dna templated	GO:0045893	266	0.016
negative regulation of developmental process	GO:0051093	201	0.016
gtp catabolic process	GO:0006184	72	0.016
negative regulation of multicellular organismal process	GO:0051241	142	0.016
cellular ketone metabolic process	GO:0042180	24	0.016
gtp metabolic process	GO:0046039	72	0.016
negative regulation of cellular component organization	GO:0051129	108	0.016
microtubule organizing center organization	GO:0031023	168	0.016
regulation of nervous system development	GO:0051960	248	0.016
response to biotic stimulus	GO:0009607	294	0.016
embryonic development via the syncytial blastoderm	GO:0001700	148	0.016
cell division	GO:0051301	248	0.016
organic substance catabolic process	GO:1901575	308	0.016
positive regulation of cellular biosynthetic process	GO:0031328	316	0.016
carbohydrate derivative biosynthetic process	GO:1901137	85	0.016
intracellular protein transport	GO:0006886	104	0.015
macromolecular complex assembly	GO:0065003	256	0.015
regulation of cellular component size	GO:0032535	98	0.015
regulation of protein modification process	GO:0031399	112	0.015
regulation of cell differentiation	GO:0045595	302	0.015
endomembrane system organization	GO:0010256	119	0.015
secretion	GO:0046903	109	0.015
axon cargo transport	GO:0008088	29	0.015
spermatogenesis	GO:0007283	200	0.015
chromatin modification	GO:0016568	147	0.015
cellular catabolic process	GO:0044248	372	0.015
response to abiotic stimulus	GO:0009628	341	0.015
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.015
formation of primary germ layer	GO:0001704	24	0.015
mapk cascade	GO:0000165	107	0.015
positive regulation of biosynthetic process	GO:0009891	316	0.015
muscle structure development	GO:0061061	224	0.015
regulation of defense response	GO:0031347	102	0.015
gliogenesis	GO:0042063	80	0.015
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.015
photoreceptor cell differentiation	GO:0046530	170	0.014
circulatory system development	GO:0072359	82	0.014
positive regulation of cellular component organization	GO:0051130	156	0.014
endocytosis	GO:0006897	310	0.014
establishment of organelle localization	GO:0051656	122	0.014
positive regulation of gtp catabolic process	GO:0033126	43	0.014
regulation of cell development	GO:0060284	215	0.014
positive regulation of nucleoside metabolic process	GO:0045979	47	0.014
regulation of gtpase activity	GO:0043087	44	0.014
purine containing compound biosynthetic process	GO:0072522	30	0.014
regulation of neurogenesis	GO:0050767	158	0.014
eye development	GO:0001654	323	0.014
male gamete generation	GO:0048232	201	0.014
positive regulation of protein modification process	GO:0031401	58	0.014
gastrulation	GO:0007369	70	0.013
positive regulation of cell migration	GO:0030335	2	0.013
positive regulation of rna metabolic process	GO:0051254	271	0.013
regulation of ras gtpase activity	GO:0032318	38	0.013
apoptotic process	GO:0006915	159	0.013
regulation of gene expression epigenetic	GO:0040029	128	0.013
macromolecule catabolic process	GO:0009057	161	0.013
positive regulation of phosphorylation	GO:0042327	87	0.013
cell growth	GO:0016049	108	0.013
programmed cell death	GO:0012501	257	0.013
regulation of nucleoside metabolic process	GO:0009118	50	0.013
telencephalon development	GO:0021537	2	0.013
establishment of vesicle localization	GO:0051650	51	0.013
compound eye morphogenesis	GO:0001745	249	0.013
eye morphogenesis	GO:0048592	260	0.013
single organism catabolic process	GO:0044712	228	0.013
death	GO:0016265	284	0.013
dendrite morphogenesis	GO:0048813	199	0.013
regulation of protein localization	GO:0032880	76	0.013
purine containing compound catabolic process	GO:0072523	112	0.013
chromatin silencing	GO:0006342	76	0.013
positive regulation of transport	GO:0051050	92	0.013
oxoacid metabolic process	GO:0043436	103	0.013
histone modification	GO:0016570	106	0.013
regulation of protein transport	GO:0051223	57	0.012
immune response activating signal transduction	GO:0002757	2	0.012
spindle organization	GO:0007051	253	0.012
kidney development	GO:0001822	3	0.012
defense response	GO:0006952	300	0.012
imaginal disc derived leg morphogenesis	GO:0007480	80	0.012
detection of chemical stimulus	GO:0009593	93	0.012
positive regulation of cell motility	GO:2000147	3	0.012
ovarian follicle cell development	GO:0030707	248	0.012
actin filament based process	GO:0030029	220	0.012
regulation of response to external stimulus	GO:0032101	115	0.012
response to extracellular stimulus	GO:0009991	116	0.012
developmental growth involved in morphogenesis	GO:0060560	65	0.012
behavioral response to ethanol	GO:0048149	49	0.012
biological adhesion	GO:0022610	138	0.012
learning or memory	GO:0007611	141	0.012
adult behavior	GO:0030534	137	0.012
regulation of nucleotide catabolic process	GO:0030811	48	0.012
regulation of multi organism process	GO:0043900	131	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
response to lipopolysaccharide	GO:0032496	4	0.012
protein ubiquitination	GO:0016567	70	0.012
regulation of neuron projection development	GO:0010975	69	0.012
heart development	GO:0007507	82	0.012
single organism nuclear import	GO:1902593	51	0.012
regulation of cellular component biogenesis	GO:0044087	201	0.012
regulation of immune response	GO:0050776	118	0.012
nucleocytoplasmic transport	GO:0006913	72	0.011
cellular amine metabolic process	GO:0044106	12	0.011
sensory perception	GO:0007600	196	0.011
stem cell proliferation	GO:0072089	88	0.011
positive regulation of gtpase activity	GO:0043547	43	0.011
rna processing	GO:0006396	147	0.011
regulation of mitotic cell cycle	GO:0007346	190	0.011
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.011
purine nucleotide catabolic process	GO:0006195	109	0.011
protein import into nucleus	GO:0006606	51	0.011
positive regulation of catabolic process	GO:0009896	105	0.011
regulation of purine nucleotide catabolic process	GO:0033121	48	0.011
chromosome segregation	GO:0007059	157	0.011
regulation of innate immune response	GO:0045088	71	0.011
regulation of gtp catabolic process	GO:0033124	44	0.011
axonogenesis	GO:0007409	290	0.011
cytoplasmic transport	GO:0016482	130	0.011
purine ribonucleoside catabolic process	GO:0046130	112	0.011
positive regulation of programmed cell death	GO:0043068	62	0.011
homeostatic process	GO:0042592	199	0.011
organonitrogen compound catabolic process	GO:1901565	128	0.011
regulation of cell proliferation	GO:0042127	163	0.011
purine nucleoside catabolic process	GO:0006152	112	0.011
meiotic cell cycle	GO:0051321	171	0.011
regulation of hydrolase activity	GO:0051336	97	0.011
response to ethanol	GO:0045471	59	0.011
positive regulation of nucleotide catabolic process	GO:0030813	46	0.011
heterocycle catabolic process	GO:0046700	166	0.011
mitotic cell cycle embryonic	GO:0045448	38	0.011
cell adhesion	GO:0007155	136	0.011
cellular amino acid metabolic process	GO:0006520	61	0.011
regulation of transferase activity	GO:0051338	58	0.011
regulation of neuron death	GO:1901214	26	0.011
regulation of protein catabolic process	GO:0042176	55	0.010
sister chromatid segregation	GO:0000819	92	0.010
regulation of immune system process	GO:0002682	176	0.010
carbohydrate derivative catabolic process	GO:1901136	118	0.010
chaeta development	GO:0022416	97	0.010
regulation of cell division	GO:0051302	72	0.010
ribonucleotide catabolic process	GO:0009261	109	0.010
cell fate determination	GO:0001709	91	0.010
positive regulation of defense response	GO:0031349	59	0.010
protein complex biogenesis	GO:0070271	201	0.010
stem cell differentiation	GO:0048863	117	0.010
rhythmic process	GO:0048511	106	0.010
regulation of proteolysis	GO:0030162	87	0.010
regulation of cellular component movement	GO:0051270	42	0.010
negative regulation of growth	GO:0045926	84	0.010

Dyb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.028
musculoskeletal system disease	DOID:17	0.020
nervous system disease	DOID:863	0.012
bone disease	DOID:0080001	0.012
connective tissue disease	DOID:65	0.012
disease of metabolism	DOID:0014667	0.010

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