Drosophila melanogaster

11 known processes

Mdr50 (Dmel_CG8523)

Multi drug resistance 50

(Aliases: CG8523,Dm3,Dm2,Dmel\CG8523,MDR50,mdr50)

Mdr50 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
endocytosisGO:00068973100.065
response to external biotic stimulusGO:00432072930.056
vesicle mediated transportGO:00161923810.053
response to lipopolysaccharideGO:003249640.050
response to abiotic stimulusGO:00096283410.050
Rat Fly
response to biotic stimulusGO:00096072940.045
response to extracellular stimulusGO:00099911160.044
Rat
oxoacid metabolic processGO:00434361030.043
small molecule metabolic processGO:00442813050.040
Fly
androgen metabolic processGO:000820910.039
steroid catabolic processGO:000670610.038
imaginal disc derived wing morphogenesisGO:00074763370.037
lateral inhibitionGO:00463312060.037
sensory perceptionGO:00076001960.036
response to other organismGO:00517072930.035
response to oxygen containing compoundGO:19017002000.034
positive regulation of signal transductionGO:00099672230.034
cellular catabolic processGO:00442483720.034
Fly
catabolic processGO:00090564090.034
Fly
organic substance transportGO:00717022570.033
Rat
phagocytosisGO:00069092150.031
xenobiotic catabolic processGO:004217810.031
negative regulation of gene expressionGO:00106293870.031
organic acid metabolic processGO:00060821030.030
response to radiationGO:00093141550.030
Rat
defense responseGO:00069523000.029
response to alcoholGO:0097305950.029
Rat
response to organic substanceGO:00100332840.029
single organism catabolic processGO:00447122280.028
Fly
wing disc morphogenesisGO:00074723440.028
post embryonic appendage morphogenesisGO:00351203850.028
imaginal disc derived appendage developmentGO:00487373990.028
positive regulation of response to stimulusGO:00485843230.028
Rat
organonitrogen compound metabolic processGO:19015643180.027
Fly
appendage developmentGO:00487364010.027
positive regulation of signalingGO:00230562430.025
single organism biosynthetic processGO:00447112060.025
organic substance catabolic processGO:19015753080.025
Fly
response to nitrogen compoundGO:1901698900.025
estrogen metabolic processGO:000821010.025
carboxylic acid metabolic processGO:0019752920.024
inter male aggressive behaviorGO:0002121600.024
positive regulation of cell communicationGO:00106472500.024
intracellular signal transductionGO:00355563000.024
cell proliferationGO:00082832990.024
Human
gland developmentGO:00487321910.024
Rat
response to starvationGO:0042594970.023
imaginal disc derived appendage morphogenesisGO:00351143950.023
appendage morphogenesisGO:00351073970.022
neurological system processGO:00508773580.022
ethanolamine containing compound metabolic processGO:004243940.022
body morphogenesisGO:001017120.022
cholesterol homeostasisGO:004263230.022
regionalizationGO:00030024160.022
response to nutrient levelsGO:00316671140.022
Rat
negative regulation of signalingGO:00230572190.022
protein complex biogenesisGO:00702712010.021
aromatic compound catabolic processGO:00194391660.021
Fly
response to organonitrogen compoundGO:0010243750.021
multi organism behaviorGO:00517051750.021
response to endogenous stimulusGO:00097191190.020
cellular amino acid metabolic processGO:0006520610.020
cellular response to chemical stimulusGO:00708871990.020
Rat
organelle fissionGO:00482853400.020
hormone catabolic processGO:004244730.020
response to organophosphorusGO:004668320.019
negative regulation of cell communicationGO:00106482230.019
cellular protein modification processGO:00064644380.019
neutral lipid biosynthetic processGO:004646020.019
open tracheal system developmentGO:00074242040.019
response to temperature stimulusGO:00092661060.019
protein modification processGO:00362114380.019
nuclear divisionGO:00002803320.019
sensory perception of smellGO:0007608800.019
amine metabolic processGO:0009308120.018
regulation of intracellular signal transductionGO:19025312360.018
organic cyclic compound catabolic processGO:19013611680.018
Fly
benzene containing compound metabolic processGO:004253730.018
cellular amine metabolic processGO:0044106120.018
cell cell signaling involved in cell fate commitmentGO:00451682100.018
regulation of multicellular organismal developmentGO:20000264140.018
response to organic cyclic compoundGO:0014070890.018
positive regulation of macromolecule metabolic processGO:00106044050.017
regulation of cell cycleGO:00517262910.017
camera type eye developmentGO:004301040.017
positive regulation of nitrogen compound metabolic processGO:00511733540.017
spermatogenesisGO:00072832000.017
kidney developmentGO:000182230.017
secondary metabolic processGO:0019748750.017
macromolecular complex assemblyGO:00650032560.017
positive regulation of nucleobase containing compound metabolic processGO:00459353320.017
carbohydrate metabolic processGO:0005975820.017
response to bacteriumGO:00096171980.017
aggressive behaviorGO:0002118630.017
establishment of localization in cellGO:00516494020.017
glycerolipid catabolic processGO:004650330.016
vitamin metabolic processGO:000676620.016
developmental growthGO:00485892800.016
spermatid differentiationGO:00485151140.016
localization of cellGO:00516742570.016
Fly
protein complex assemblyGO:00064612000.016
negative regulation of response to stimulusGO:00485852580.016
regulation of cellular ketone metabolic processGO:001056530.016
growthGO:00400073590.016
negative regulation of cellular metabolic processGO:00313243820.016
regulation of cell differentiationGO:00455953020.016
axonogenesisGO:00074092900.015
sensory perception of chemical stimulusGO:00076061160.015
heterocycle catabolic processGO:00467001660.015
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.015
cellular response to organic substanceGO:00713101320.015
Rat
lipid metabolic processGO:00066291210.015
male gamete generationGO:00482322010.015
acylglycerol catabolic processGO:004646430.015
cellular response to endogenous stimulusGO:0071495800.015
Rat
transcription from rna polymerase ii promoterGO:00063663680.015
immune response activating signal transductionGO:000275720.015
cell motilityGO:00488702510.015
Fly
intracellular transportGO:00469072280.015
cell deathGO:00082192790.015
Rat
immune response regulating signaling pathwayGO:000276420.015
ion transportGO:00068111450.015
Rat
single organism intracellular transportGO:19025822070.015
regulation of molecular functionGO:00650092170.015
morphogenesis of an epitheliumGO:00020092760.015
cellular lipid metabolic processGO:0044255830.014
single organism carbohydrate metabolic processGO:0044723720.014
single organism behaviorGO:00447083910.014
determination of adult lifespanGO:00083401370.014
compound eye developmentGO:00487493070.014
protein localizationGO:00081042840.014
deathGO:00162652840.014
Rat
cellular macromolecule localizationGO:00707272200.014
anion homeostasisGO:005508130.014
cellular ketone metabolic processGO:0042180240.014
immune system processGO:00023763470.014
homeostatic processGO:00425921990.014
cellular response to ethanolGO:007136140.014
sensory organ morphogenesisGO:00905962600.014
phosphorylationGO:00163102940.014
taxisGO:00423303040.014
matingGO:00076181200.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
positive regulation of intracellular signal transductionGO:19025331160.013
negative regulation of macromolecule biosynthetic processGO:00105582700.013
phosphatidylethanolamine metabolic processGO:004633710.013
rna processingGO:00063961470.013
salivary gland morphogenesisGO:00074351450.013
meiotic cell cycleGO:00513211710.013
regulation of anatomical structure morphogenesisGO:00226032420.013
tissue morphogenesisGO:00487292970.013
chemical homeostasisGO:0048878920.013
regulation of cell deathGO:00109411730.013
Rat
regulation of immune system processGO:00026821760.013
neuron projection guidanceGO:00974852410.013
carbohydrate derivative metabolic processGO:19011352170.013
Fly
multicellular organismal agingGO:00102591400.013
positive regulation of gene expressionGO:00106282900.013
regulation of cellular amine metabolic processGO:003323830.013
regulation of response to stressGO:00801342000.013
response to ethanolGO:0045471590.013
regulation of localizationGO:00328792750.013
developmental maturationGO:00217001720.013
negative regulation of biosynthetic processGO:00098902770.013
synapse organizationGO:00508081960.013
organic hydroxy compound metabolic processGO:1901615830.013
regulation of catalytic activityGO:00507901850.013
regulation of transcription from rna polymerase ii promoterGO:00063573780.013
acylglycerol biosynthetic processGO:004646320.012
compound eye morphogenesisGO:00017452490.012
pigmentationGO:0043473750.012
regulation of cell cycle processGO:00105641810.012
response to ketoneGO:1901654340.012
Rat
forebrain developmentGO:003090020.012
connective tissue developmentGO:006144830.012
cell migrationGO:00164772380.012
Fly
positive regulation of rna metabolic processGO:00512542710.012
cellular response to dna damage stimulusGO:00069742230.012
immune responseGO:00069552460.012
regulation of growthGO:00400082330.012
eye morphogenesisGO:00485922600.012
meiotic cell cycle processGO:19030461320.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
synapse assemblyGO:00074161430.012
developmental pigmentationGO:0048066680.012
positive regulation of rna biosynthetic processGO:19026802660.012
positive regulation of biosynthetic processGO:00098913160.012
eye developmentGO:00016543230.012
cytoplasmic transportGO:00164821300.012
positive regulation of multicellular organismal processGO:00512401430.012
proteolysisGO:00065081920.012
respiratory system developmentGO:00605412130.012
response to alkaloidGO:0043279260.012
Rat
regulation of phosphorus metabolic processGO:00511742100.012
hormone metabolic processGO:0042445330.012
chromosome segregationGO:00070591570.012
chemotaxisGO:00069352490.012
single organism cellular localizationGO:19025801800.012
regulation of cellular amino acid metabolic processGO:000652100.012
regulation of lipid transportGO:003236830.011
negative regulation of developmental processGO:00510932010.011
alditol phosphate metabolic processGO:005264620.011
cellular nitrogen compound catabolic processGO:00442701650.011
Fly
positive regulation of macromolecule biosynthetic processGO:00105572830.011
protein transportGO:00150311550.011
regulation of catabolic processGO:00098941700.011
defense response to other organismGO:00985422250.011
endomembrane system organizationGO:00102561190.011
positive regulation of cellular biosynthetic processGO:00313283160.011
programmed cell deathGO:00125012570.011
axon developmentGO:00615642970.011
developmental programmed cell deathGO:00106231380.011
cellular response to oxygen containing compoundGO:1901701790.011
Rat
epithelial cell differentiationGO:00308553220.011
Rat
mitotic nuclear divisionGO:00070672130.011
synaptic transmissionGO:00072682880.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
columnar cuboidal epithelial cell developmentGO:00020662490.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
cuticle developmentGO:0042335860.011
axon guidanceGO:00074112330.011
monocarboxylic acid transportGO:001571830.011
positive regulation of transcription dna templatedGO:00458932660.011
regulation of protein metabolic processGO:00512462560.011
cellular macromolecular complex assemblyGO:00346221530.011
embryonic development via the syncytial blastodermGO:00017001480.011
triglyceride catabolic processGO:001943330.011
regulation of transportGO:00510491810.011
ovarian follicle cell developmentGO:00307072480.011
acetate ester metabolic processGO:190061920.011
cell divisionGO:00513012480.011
negative regulation of cellular biosynthetic processGO:00313272770.011
segmentationGO:00352822070.011
circadian rhythmGO:00076231050.011
Rat
pigment biosynthetic processGO:0046148360.011
response to copper ionGO:004668840.010
eye pigment metabolic processGO:0042441330.010
actin filament based processGO:00300292200.010
maintenance of locationGO:0051235730.010
establishment of protein localizationGO:00451841630.010
regulation of developmental growthGO:00486381740.010
autophagyGO:00069141080.010
gene silencingGO:00164581380.010
rna localizationGO:00064031150.010
cation transportGO:00068121100.010
Rat
hindbrain developmentGO:003090220.010
negative regulation of signal transductionGO:00099682060.010
response to light stimulusGO:00094161240.010
organophosphate catabolic processGO:00464341120.010
Fly
small gtpase mediated signal transductionGO:0007264880.010
negative regulation of rna metabolic processGO:00512532510.010
regulation of cellular component biogenesisGO:00440872010.010
regulation of defense responseGO:00313471020.010
chemosensory behaviorGO:00076351060.010
positive regulation of nucleic acid templated transcriptionGO:19035082660.010
regulation of i kappab kinase nf kappab signalingGO:004312220.010
chaeta developmentGO:0022416970.010
cell recognitionGO:00080371020.010
regulation of cell developmentGO:00602842150.010
organophosphate metabolic processGO:00196371950.010
Fly
salivary gland developmentGO:00074311620.010
cellular protein localizationGO:00346131600.010
chromosome organizationGO:00512763600.010
sterol homeostasisGO:005509240.010

Mdr50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
Human
disease of metabolismDOID:001466700.030
inherited metabolic disorderDOID:65500.020
integumentary system diseaseDOID:1600.015
hair diseaseDOID:42100.015
hypotrichosisDOID:453500.015
nervous system diseaseDOID:86300.012
lipid metabolism disorderDOID:314600.012
familial hypertriglyceridemiaDOID:005052700.012
cardiovascular system diseaseDOID:128700.011
vascular diseaseDOID:17800.011
acquired metabolic diseaseDOID:006015800.011
carbohydrate metabolism diseaseDOID:005001300.011
type 2 diabetes mellitusDOID:935200.011
glucose metabolism diseaseDOID:419400.011
diabetes mellitusDOID:935100.011