IMP: Integrative Multi-species Prediction

Drosophila melanogaster

52 known processes

CG11242 (Dmel_CG11242)

CG11242 gene product from transcript CG11242-RA

(Aliases: Dmel\CG11242)

Entrez: 37244
FLYBASE: FBgn0034451
UniProtKB: A1ZBM2

Process Predictions
Disease Predictions

CG11242 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
embryo development ending in birth or egg hatching	GO:0009792	152	0.597
chromosome organization	GO:0051276	360	0.508
protein modification process	GO:0036211	438	0.372
protein complex assembly	GO:0006461	200	0.360
actin filament based process	GO:0030029	220	0.355
macromolecular complex assembly	GO:0065003	256	0.335
vesicle mediated transport	GO:0016192	381	0.327
protein complex biogenesis	GO:0070271	201	0.225
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.215
regulation of response to stress	GO:0080134	200	0.211
regulation of cellular component biogenesis	GO:0044087	201	0.210
epithelial cell differentiation	GO:0030855	322	0.206
response to bacterium	GO:0009617	198	0.196
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.184
positive regulation of rna metabolic process	GO:0051254	271	0.171
neurological system process	GO:0050877	358	0.159
larval development	GO:0002164	104	0.153
regulation of protein metabolic process	GO:0051246	256	0.149
single organism behavior	GO:0044708	391	0.148
positive regulation of transcription dna templated	GO:0045893	266	0.146
endocytosis	GO:0006897	310	0.143
protein acetylation	GO:0006473	39	0.140
transcription from rna polymerase ii promoter	GO:0006366	368	0.139
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.136
spermatogenesis	GO:0007283	200	0.136
regulation of cellular protein metabolic process	GO:0032268	243	0.127
compound eye development	GO:0048749	307	0.124
cellular protein complex disassembly	GO:0043624	35	0.118
regulation of transport	GO:0051049	181	0.115
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.113
epithelial cell development	GO:0002064	274	0.112
cell death	GO:0008219	279	0.110
cellular protein modification process	GO:0006464	438	0.107
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.105
eye development	GO:0001654	323	0.105
membrane organization	GO:0061024	112	0.103
defense response	GO:0006952	300	0.103
defense response to other organism	GO:0098542	225	0.102
determination of adult lifespan	GO:0008340	137	0.101
regulation of protein modification process	GO:0031399	112	0.099
positive regulation of signal transduction	GO:0009967	223	0.097
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.096
positive regulation of cellular biosynthetic process	GO:0031328	316	0.096
death	GO:0016265	284	0.096
regulation of lamellipodium organization	GO:1902743	15	0.094
positive regulation of rna biosynthetic process	GO:1902680	266	0.093
columnar cuboidal epithelial cell development	GO:0002066	249	0.091
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.087
negative regulation of cell death	GO:0060548	81	0.086
negative regulation of cell cycle process	GO:0010948	109	0.085
axon cargo transport	GO:0008088	29	0.083
nucleus organization	GO:0006997	45	0.083
positive regulation of response to stimulus	GO:0048584	323	0.082
single organism cellular localization	GO:1902580	180	0.080
regulation of catabolic process	GO:0009894	170	0.079
secondary metabolic process	GO:0019748	75	0.079
microtubule based transport	GO:0010970	42	0.078
synaptic transmission	GO:0007268	288	0.077
response to organic cyclic compound	GO:0014070	89	0.076
cellularization	GO:0007349	90	0.073
cytoskeleton dependent intracellular transport	GO:0030705	44	0.072
phosphorylation	GO:0016310	294	0.072
positive regulation of macromolecule metabolic process	GO:0010604	405	0.071
establishment or maintenance of cell polarity	GO:0007163	167	0.071
nuclear migration	GO:0007097	20	0.071
cellular ketone metabolic process	GO:0042180	24	0.070
regulation of cellular response to stress	GO:0080135	89	0.068
negative regulation of signaling	GO:0023057	219	0.067
internal peptidyl lysine acetylation	GO:0018393	38	0.066
protein modification by small protein conjugation or removal	GO:0070647	106	0.064
histone acetylation	GO:0016573	38	0.063
regulation of cell death	GO:0010941	173	0.063
immune response	GO:0006955	246	0.061
developmental growth	GO:0048589	280	0.061
tissue morphogenesis	GO:0048729	297	0.060
cellular catabolic process	GO:0044248	372	0.060
microtubule organizing center organization	GO:0031023	168	0.060
pigment metabolic process	GO:0042440	84	0.059
regulation of cell morphogenesis	GO:0022604	163	0.059
response to external biotic stimulus	GO:0043207	293	0.058
regulation of protein complex assembly	GO:0043254	42	0.056
single organism intracellular transport	GO:1902582	207	0.055
central nervous system development	GO:0007417	201	0.055
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.055
protein maturation	GO:0051604	71	0.055
signal transduction by phosphorylation	GO:0023014	107	0.054
intracellular transport	GO:0046907	228	0.053
regulation of phosphorylation	GO:0042325	147	0.052
regulation of cellular amino acid metabolic process	GO:0006521	0	0.051
response to endogenous stimulus	GO:0009719	119	0.051
single fertilization	GO:0007338	24	0.050
negative regulation of response to stimulus	GO:0048585	258	0.050
response to organic substance	GO:0010033	284	0.050
cellular protein complex assembly	GO:0043623	71	0.049
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.048
positive regulation of developmental growth	GO:0048639	62	0.048
eye morphogenesis	GO:0048592	260	0.047
negative regulation of signal transduction	GO:0009968	206	0.047
negative regulation of cellular metabolic process	GO:0031324	382	0.047
germarium derived oocyte differentiation	GO:0030706	29	0.047
proteolysis	GO:0006508	192	0.047
intracellular signal transduction	GO:0035556	300	0.047
negative regulation of cell communication	GO:0010648	223	0.046
gonad development	GO:0008406	50	0.046
positive regulation of signaling	GO:0023056	243	0.045
innate immune response	GO:0045087	144	0.045
positive regulation of biosynthetic process	GO:0009891	316	0.044
mitotic dna damage checkpoint	GO:0044773	74	0.043
mapk cascade	GO:0000165	107	0.043
apoptotic process	GO:0006915	159	0.043
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.043
response to biotic stimulus	GO:0009607	294	0.042
negative regulation of gene expression	GO:0010629	387	0.042
membrane depolarization	GO:0051899	4	0.042
regulation of apoptotic process	GO:0042981	130	0.042
negative regulation of mitotic cell cycle	GO:0045930	109	0.042
protein localization	GO:0008104	284	0.041
positive regulation of growth	GO:0045927	75	0.041
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.041
positive regulation of cellular component biogenesis	GO:0044089	80	0.041
response to other organism	GO:0051707	293	0.041
embryonic development via the syncytial blastoderm	GO:0001700	148	0.040
female germ line cyst formation	GO:0048135	42	0.040
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.039
response to abiotic stimulus	GO:0009628	341	0.039
regulation of dna templated transcription elongation	GO:0032784	17	0.039
cellular macromolecular complex assembly	GO:0034622	153	0.039
negative regulation of cell cycle	GO:0045786	116	0.039
regulation of cell projection organization	GO:0031344	92	0.038
immune system process	GO:0002376	347	0.038
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.038
development of primary sexual characteristics	GO:0045137	50	0.037
intracellular protein transport	GO:0006886	104	0.037
sex differentiation	GO:0007548	81	0.037
fertilization	GO:0009566	26	0.036
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.036
carboxylic acid metabolic process	GO:0019752	92	0.036
regulation of catalytic activity	GO:0050790	185	0.036
sensory perception	GO:0007600	196	0.036
single organism membrane organization	GO:0044802	93	0.035
regulation of cellular ketone metabolic process	GO:0010565	3	0.035
hemocyte differentiation	GO:0042386	38	0.035
peptidyl lysine modification	GO:0018205	57	0.035
regulation of phosphate metabolic process	GO:0019220	210	0.034
regulation of programmed cell death	GO:0043067	152	0.034
phagocytosis	GO:0006909	215	0.033
reproductive structure development	GO:0048608	74	0.033
regulation of developmental growth	GO:0048638	174	0.033
genitalia development	GO:0048806	26	0.033
growth	GO:0040007	359	0.032
regulation of cellular localization	GO:0060341	136	0.032
regulation of ras protein signal transduction	GO:0046578	93	0.032
response to radiation	GO:0009314	155	0.031
regulation of growth	GO:0040008	233	0.031
positive regulation of cell communication	GO:0010647	250	0.031
positive regulation of response to wounding	GO:1903036	15	0.030
protein localization to plasma membrane	GO:0072659	13	0.030
body morphogenesis	GO:0010171	2	0.030
programmed cell death	GO:0012501	257	0.030
protein processing	GO:0016485	68	0.030
oocyte development	GO:0048599	124	0.030
neuromuscular synaptic transmission	GO:0007274	67	0.029
establishment of nucleus localization	GO:0040023	26	0.029
negative regulation of phosphorus metabolic process	GO:0010563	45	0.029
cognition	GO:0050890	141	0.029
mitotic cell cycle checkpoint	GO:0007093	88	0.028
multicellular organismal aging	GO:0010259	140	0.028
response to oxygen levels	GO:0070482	59	0.028
regulation of molecular function	GO:0065009	217	0.028
reproductive system development	GO:0061458	74	0.028
retrograde axon cargo transport	GO:0008090	9	0.028
actin cytoskeleton organization	GO:0030036	206	0.028
negative regulation of programmed cell death	GO:0043069	72	0.027
positive regulation of developmental process	GO:0051094	143	0.027
defense response to gram negative bacterium	GO:0050829	94	0.027
regulation of vesicle mediated transport	GO:0060627	59	0.027
cellular component disassembly	GO:0022411	46	0.026
positive regulation of protein metabolic process	GO:0051247	128	0.026
multi organism behavior	GO:0051705	175	0.026
negative regulation of protein metabolic process	GO:0051248	85	0.026
sensory organ morphogenesis	GO:0090596	260	0.025
small molecule metabolic process	GO:0044281	305	0.025
chromatin organization	GO:0006325	207	0.025
positive regulation of protein modification process	GO:0031401	58	0.025
centrosome organization	GO:0051297	163	0.025
female meiotic division	GO:0007143	70	0.025
mitotic dna integrity checkpoint	GO:0044774	75	0.024
regulation of cellular component movement	GO:0051270	42	0.024
regulation of cell shape	GO:0008360	113	0.024
negative regulation of catalytic activity	GO:0043086	42	0.024
defense response to bacterium	GO:0042742	178	0.024
nitrogen compound transport	GO:0071705	85	0.024
peptidyl lysine acetylation	GO:0018394	39	0.024
oxoacid metabolic process	GO:0043436	103	0.024
regulation of innate immune response	GO:0045088	71	0.024
organic acid metabolic process	GO:0006082	103	0.023
catabolic process	GO:0009056	409	0.023
cellular amine metabolic process	GO:0044106	12	0.023
germ line cyst formation	GO:0048134	44	0.023
response to nitrogen compound	GO:1901698	90	0.023
male gamete generation	GO:0048232	201	0.023
regulation of protein phosphorylation	GO:0001932	64	0.023
compound eye morphogenesis	GO:0001745	249	0.023
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.023
cellular protein localization	GO:0034613	160	0.023
macromolecular complex disassembly	GO:0032984	37	0.022
golgi vesicle transport	GO:0048193	27	0.022
ras protein signal transduction	GO:0007265	88	0.021
negative regulation of cellular component organization	GO:0051129	108	0.021
cell cycle checkpoint	GO:0000075	95	0.021
regulation of protein catabolic process	GO:0042176	55	0.021
negative regulation of cellular biosynthetic process	GO:0031327	277	0.021
positive regulation of autophagy	GO:0010508	21	0.021
endomembrane system organization	GO:0010256	119	0.021
positive regulation of multicellular organismal process	GO:0051240	143	0.021
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.020
response to light stimulus	GO:0009416	124	0.020
regulation of membrane potential	GO:0042391	35	0.020
establishment of protein localization	GO:0045184	163	0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.020
stress activated protein kinase signaling cascade	GO:0031098	55	0.020
locomotory behavior	GO:0007626	176	0.020
melanin metabolic process	GO:0006582	47	0.019
chemosensory behavior	GO:0007635	106	0.019
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.019
endosomal vesicle fusion	GO:0034058	4	0.019
germarium derived female germ line cyst formation	GO:0030727	42	0.019
macromolecule catabolic process	GO:0009057	161	0.019
asymmetric cell division	GO:0008356	37	0.019
jnk cascade	GO:0007254	50	0.019
epithelial cell migration	GO:0010631	148	0.019
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.019
regulation of phosphorus metabolic process	GO:0051174	210	0.018
lymph gland development	GO:0048542	28	0.018
organic substance catabolic process	GO:1901575	308	0.018
modification dependent protein catabolic process	GO:0019941	78	0.018
regulation of cellular amine metabolic process	GO:0033238	3	0.018
cellular macromolecule localization	GO:0070727	220	0.018
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0030722	6	0.018
posttranscriptional regulation of gene expression	GO:0010608	145	0.018
cell proliferation	GO:0008283	299	0.018
regulation of cell projection assembly	GO:0060491	30	0.018
localization of cell	GO:0051674	257	0.017
dendrite development	GO:0016358	204	0.017
protein ubiquitination	GO:0016567	70	0.017
positive regulation of gene expression	GO:0010628	290	0.017
anterograde axon cargo transport	GO:0008089	6	0.017
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.017
protein acylation	GO:0043543	42	0.017
positive regulation of cell projection organization	GO:0031346	29	0.017
regulation of cell differentiation	GO:0045595	302	0.016
cytoplasmic transport	GO:0016482	130	0.016
mitotic cytokinesis	GO:0000281	50	0.016
endosomal transport	GO:0016197	44	0.016
regulation of intracellular transport	GO:0032386	64	0.016
regulation of hydrolase activity	GO:0051336	97	0.016
protein catabolic process	GO:0030163	101	0.016
positive regulation of immune response	GO:0050778	63	0.016
transcription elongation from rna polymerase ii promoter	GO:0006368	18	0.016
regulation of nervous system development	GO:0051960	248	0.016
cellular response to heat	GO:0034605	24	0.016
protein complex disassembly	GO:0043241	36	0.016
negative regulation of apoptotic process	GO:0043066	63	0.016
protein heterooligomerization	GO:0051291	4	0.016
cellular response to organic substance	GO:0071310	132	0.016
wound healing	GO:0042060	75	0.015
internal protein amino acid acetylation	GO:0006475	38	0.015
positive regulation of cellular protein metabolic process	GO:0032270	118	0.015
multi multicellular organism process	GO:0044706	123	0.015
maintenance of location	GO:0051235	73	0.015
lamellipodium organization	GO:0097581	21	0.015
negative regulation of phosphate metabolic process	GO:0045936	45	0.014
morphogenesis of embryonic epithelium	GO:0016331	94	0.014
g2 dna damage checkpoint	GO:0031572	69	0.014
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO:0070059	4	0.014
response to oxygen containing compound	GO:1901700	200	0.014
reproductive behavior	GO:0019098	122	0.014
erbb signaling pathway	GO:0038127	58	0.014
establishment of protein localization to organelle	GO:0072594	62	0.014
hematopoietic progenitor cell differentiation	GO:0002244	1	0.014
amine metabolic process	GO:0009308	12	0.014
pole plasm oskar mrna localization	GO:0045451	46	0.013
regulation of phospholipase activity	GO:0010517	2	0.013
synaptic growth at neuromuscular junction	GO:0051124	119	0.013
microtubule based movement	GO:0007018	51	0.013
regulation of cell development	GO:0060284	215	0.013
retrograde transport endosome to golgi	GO:0042147	3	0.013
mitotic cell cycle phase transition	GO:0044772	138	0.013
oocyte fate determination	GO:0030716	27	0.013
response to starvation	GO:0042594	97	0.013
photoreceptor cell differentiation	GO:0046530	170	0.013
gliogenesis	GO:0042063	80	0.013
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.013
response to decreased oxygen levels	GO:0036293	58	0.013
golgi to plasma membrane transport	GO:0006893	8	0.013
regulation of intracellular signal transduction	GO:1902531	236	0.013
organic substance transport	GO:0071702	257	0.013
positive regulation of catalytic activity	GO:0043085	118	0.013
regulation of synaptic transmission	GO:0050804	69	0.013
developmental maturation	GO:0021700	172	0.013
regulation of peptidase activity	GO:0052547	39	0.012
regulation of anatomical structure morphogenesis	GO:0022603	242	0.012
response to wounding	GO:0009611	94	0.012
defense response to fungus	GO:0050832	48	0.012
pronuclear migration	GO:0035046	4	0.012
peptidyl amino acid modification	GO:0018193	105	0.012
brain development	GO:0007420	120	0.012
positive regulation of response to nutrient levels	GO:0032109	8	0.012
ameboidal type cell migration	GO:0001667	151	0.012
protein transport	GO:0015031	155	0.012
eye pigment metabolic process	GO:0042441	33	0.012
positive regulation of transport	GO:0051050	92	0.012
positive regulation of defense response	GO:0031349	59	0.012
forebrain development	GO:0030900	2	0.012
organelle assembly	GO:0070925	198	0.012
regulation of jnk cascade	GO:0046328	40	0.012
embryonic morphogenesis	GO:0048598	206	0.012
rna localization	GO:0006403	115	0.012
reactive oxygen species metabolic process	GO:0072593	22	0.012
camera type eye development	GO:0043010	4	0.012
imaginal disc derived wing morphogenesis	GO:0007476	337	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
histone h4 acetylation	GO:0043967	13	0.012
negative regulation of intracellular signal transduction	GO:1902532	57	0.012
ocellus pigmentation	GO:0033060	19	0.012
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.011
response to hypoxia	GO:0001666	53	0.011
nucleus localization	GO:0051647	34	0.011
response to nutrient levels	GO:0031667	114	0.011
regulation of locomotion	GO:0040012	42	0.011
regulation of localization	GO:0032879	275	0.011
aging	GO:0007568	143	0.011
positive regulation of cell motility	GO:2000147	3	0.011
negative regulation of organelle organization	GO:0010639	56	0.011
regulation of mapk cascade	GO:0043408	92	0.011
extrinsic apoptotic signaling pathway	GO:0097191	1	0.011
cell projection assembly	GO:0030031	94	0.011
adult behavior	GO:0030534	137	0.011
cellular response to chemical stimulus	GO:0070887	199	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
negative regulation of biosynthetic process	GO:0009890	277	0.011
protein deubiquitination	GO:0016579	17	0.011
positive regulation of cellular component organization	GO:0051130	156	0.011
establishment of localization in cell	GO:0051649	402	0.011
regulation of immune response	GO:0050776	118	0.010
dna integrity checkpoint	GO:0031570	81	0.010
peptidyl lysine trimethylation	GO:0018023	6	0.010
positive regulation of phosphorus metabolic process	GO:0010562	139	0.010
regulation of cytoskeleton organization	GO:0051493	89	0.010
chromosome segregation	GO:0007059	157	0.010
protein phosphorylation	GO:0006468	169	0.010
regulation of synapse organization	GO:0050807	110	0.010
protein modification by small protein conjugation	GO:0032446	79	0.010

CG11242 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.243
nervous system disease	DOID:863	0.027
central nervous system disease	DOID:331	0.010

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