Drosophila melanogaster

67 known processes

Mcm3 (Dmel_CG4206)

Minichromosome maintenance 3

(Aliases: DmMCM3,dMCM3,CG4206,PCR2,DmMcm3,DmeMCM3,MCM3,Mcp-PCR2,Dmel\CG4206,McM3)

Mcm3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
recombinational repairGO:0000725130.767
Yeast
dna replicationGO:0006260480.760
Yeast
double strand break repairGO:0006302260.673
Yeast
dna geometric changeGO:0032392160.665
mitotic dna integrity checkpointGO:0044774750.663
dna repairGO:0006281540.657
Yeast
double strand break repair via nonhomologous end joiningGO:000630350.622
mitotic dna damage checkpointGO:0044773740.580
dna recombinationGO:0006310320.503
Yeast
reciprocal meiotic recombinationGO:0007131190.444
mitotic g2 dna damage checkpointGO:0007095690.433
double strand break repair via homologous recombinationGO:0000724130.406
Yeast
translesion synthesisGO:001998520.374
negative regulation of cell cycle phase transitionGO:19019881030.350
dna damage checkpointGO:0000077780.321
dna metabolic processGO:00062592270.314
g2 dna damage checkpointGO:0031572690.298
zymogen activationGO:0031638200.242
meiotic chromosome segregationGO:0045132590.235
dna conformation changeGO:00711031050.229
cell cycle dna replicationGO:0044786230.218
Yeast
regulation of cell cycleGO:00517262910.218
organic substance catabolic processGO:19015753080.212
Yeast
cellular response to dna damage stimulusGO:00069742230.206
chromosome organizationGO:00512763600.183
nuclear dna replicationGO:003326010.176
Yeast
dna integrity checkpointGO:0031570810.171
chromosome segregationGO:00070591570.161
chromosome condensationGO:0030261410.157
regulation of dna metabolic processGO:0051052340.157
non recombinational repairGO:000072670.155
single organism biosynthetic processGO:00447112060.149
Yeast
dna packagingGO:0006323910.144
heterocycle catabolic processGO:00467001660.138
Yeast
cell cycle checkpointGO:0000075950.136
regulation of cell cycle processGO:00105641810.131
organelle fissionGO:00482853400.129
nuclear divisionGO:00002803320.128
nucleobase containing compound catabolic processGO:00346551650.127
Yeast
embryo development ending in birth or egg hatchingGO:00097921520.124
Worm
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.114
Yeast
positive regulation of peptidase activityGO:0010952290.112
mitotic cell cycle checkpointGO:0007093880.110
deathGO:00162652840.108
mitotic spindle elongationGO:0000022810.107
cell cycle phase transitionGO:00447701400.107
mitotic cell cycle phase transitionGO:00447721380.094
mitotic g2 m transition checkpointGO:0044818700.088
negative regulation of cell cycle processGO:00109481090.086
macromolecular complex assemblyGO:00650032560.084
Yeast
aromatic compound catabolic processGO:00194391660.083
Yeast
catabolic processGO:00090564090.080
Yeast
single organism intracellular transportGO:19025822070.080
negative regulation of mitotic cell cycleGO:00459301090.078
negative regulation of cellular biosynthetic processGO:00313272770.077
Yeast
positive regulation of macromolecule metabolic processGO:00106044050.076
positive regulation of nitrogen compound metabolic processGO:00511733540.072
regulation of multicellular organismal developmentGO:20000264140.071
programmed cell deathGO:00125012570.071
endocytosisGO:00068973100.070
negative regulation of nucleic acid templated transcriptionGO:19035072400.070
Yeast
cellular macromolecule localizationGO:00707272200.070
regulation of apoptotic processGO:00429811300.069
postreplication repairGO:000630120.068
regulation of cellular response to stressGO:0080135890.068
nucleotide excision repairGO:000628980.068
cellular nitrogen compound catabolic processGO:00442701650.067
Yeast
cell proliferationGO:00082832990.067
cell deathGO:00082192790.063
dna replication initiationGO:000627060.061
Yeast
spindle elongationGO:0051231830.061
negative regulation of cell cycleGO:00457861160.061
positive regulation of nucleobase containing compound metabolic processGO:00459353320.060
regulation of cell deathGO:00109411730.059
phosphorylationGO:00163102940.058
regulation of dna repairGO:000628250.057
small molecule metabolic processGO:00442813050.057
Yeast
regulation of mitotic cell cycleGO:00073461900.057
cellular catabolic processGO:00442483720.056
Yeast
regulation of cysteine type endopeptidase activityGO:2000116270.056
organic cyclic compound catabolic processGO:19013611680.055
Yeast
vesicle mediated transportGO:00161923810.054
negative regulation of gene expression epigeneticGO:0045814770.053
Yeast
regulation of dna recombinationGO:000001840.051
reciprocal dna recombinationGO:0035825190.051
homeostatic processGO:00425921990.050
regulation of programmed cell deathGO:00430671520.050
dna dependent dna replicationGO:0006261170.050
Yeast
negative regulation of nitrogen compound metabolic processGO:00511722650.048
Yeast
mitotic nuclear divisionGO:00070672130.048
dna double strand break processingGO:000072930.047
regulation of mitotic cell cycle phase transitionGO:19019901300.047
regulation of organelle organizationGO:00330431960.046
ribonucleoside metabolic processGO:00091191270.046
Yeast
negative regulation of rna metabolic processGO:00512532510.046
Yeast
ribose phosphate metabolic processGO:00196931450.046
Yeast
cell divisionGO:00513012480.046
mitotic spindle organizationGO:00070522200.045
nucleoside triphosphate metabolic processGO:00091411200.045
Yeast
larval developmentGO:00021641040.045
meiotic nuclear divisionGO:00071261510.041
regulation of catabolic processGO:00098941700.040
regulation of cell cycle phase transitionGO:19019871300.040
regulation of response to stressGO:00801342000.039
negative regulation of programmed cell deathGO:0043069720.038
spindle organizationGO:00070512530.038
positive regulation of nucleic acid templated transcriptionGO:19035082660.037
regulation of cellular protein metabolic processGO:00322682430.037
meiosis iGO:0007127590.037
establishment of localization in cellGO:00516494020.037
cellular macromolecule catabolic processGO:00442651360.036
regulation of cell proliferationGO:00421271630.036
cellular protein complex assemblyGO:0043623710.036
regulation of dna replicationGO:0006275130.035
organonitrogen compound metabolic processGO:19015643180.034
Yeast
g1 s transition of mitotic cell cycleGO:0000082310.034
response to radiationGO:00093141550.034
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.033
negative regulation of nucleobase containing compound metabolic processGO:00459342610.033
Yeast
regulation of double strand break repairGO:200077930.033
dna endoreduplicationGO:0042023220.033
regulation of chromosome organizationGO:0033044640.033
cellular response to radiationGO:0071478520.032
cell cycle g1 s phase transitionGO:0044843310.032
negative regulation of transcription dna templatedGO:00458922370.032
Yeast
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
protein dna complex assemblyGO:0065004630.031
Yeast
apoptotic processGO:00069151590.031
negative regulation of cellular component organizationGO:00511291080.031
regulation of cell divisionGO:0051302720.030
regulation of cell differentiationGO:00455953020.030
regulation of cellular catabolic processGO:00313291570.030
regulation of meiosisGO:004002030.030
notch signaling pathwayGO:00072191200.030
nucleoside phosphate metabolic processGO:00067531620.030
Yeast
positive regulation of biosynthetic processGO:00098913160.029
macromolecule catabolic processGO:00090571610.029
regulation of phosphate metabolic processGO:00192202100.029
regulation of dna dependent dna replicationGO:009032960.028
ribonucleoside monophosphate metabolic processGO:0009161510.028
Yeast
activation of cysteine type endopeptidase activityGO:0097202170.028
camera type eye developmentGO:004301040.028
regulation of molecular functionGO:00650092170.028
response to abiotic stimulusGO:00096283410.027
negative regulation of apoptotic processGO:0043066630.027
organonitrogen compound catabolic processGO:19015651280.027
Yeast
meiotic cell cycleGO:00513211710.027
positive regulation of hydrolase activityGO:0051345780.027
regulation of protein complex disassemblyGO:0043244290.027
dna duplex unwindingGO:0032508160.027
regulation of cell developmentGO:00602842150.026
positive regulation of catalytic activityGO:00430851180.026
response to other organismGO:00517072930.026
negative regulation of gene expressionGO:00106293870.026
Yeast
body morphogenesisGO:001017120.026
regulation of phosphorus metabolic processGO:00511742100.024
positive regulation of gene expressionGO:00106282900.024
purine containing compound metabolic processGO:00725211550.024
Yeast
nucleobase containing small molecule metabolic processGO:00550861740.023
Yeast
organophosphate metabolic processGO:00196371950.023
Yeast
purine ribonucleoside triphosphate metabolic processGO:00092051190.023
Yeast
response to light stimulusGO:00094161240.022
carboxylic acid metabolic processGO:0019752920.021
nucleoside triphosphate catabolic processGO:00091431080.021
Yeast
ribonucleoside catabolic processGO:00424541120.021
Yeast
anatomical structure homeostasisGO:0060249970.021
single organism catabolic processGO:00447122280.021
Yeast
positive regulation of protein metabolic processGO:00512471280.020
immune responseGO:00069552460.020
regulation of catalytic activityGO:00507901850.020
purine nucleotide metabolic processGO:00061631460.020
Yeast
response to ionizing radiationGO:0010212320.020
positive regulation of developmental processGO:00510941430.020
regulation of response to dna damage stimulusGO:2001020230.020
negative regulation of macromolecule biosynthetic processGO:00105582700.020
Yeast
purine ribonucleoside metabolic processGO:00461281270.020
Yeast
intracellular transportGO:00469072280.019
ribonucleotide catabolic processGO:00092611090.019
Yeast
agingGO:00075681430.019
positive regulation of cellular protein metabolic processGO:00322701180.019
intracellular signal transductionGO:00355563000.019
connective tissue developmentGO:006144830.019
growthGO:00400073590.019
transcription from rna polymerase ii promoterGO:00063663680.019
negative regulation of rna biosynthetic processGO:19026792400.019
Yeast
single organism cellular localizationGO:19025801800.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.018
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.018
purine ribonucleoside catabolic processGO:00461301120.018
Yeast
protein complex assemblyGO:00064612000.018
female meiosis chromosome segregationGO:0016321330.018
eye developmentGO:00016543230.018
negative regulation of biosynthetic processGO:00098902770.017
Yeast
dna biosynthetic processGO:0071897240.017
purine ribonucleotide catabolic processGO:00091541090.017
Yeast
purine ribonucleotide metabolic processGO:00091501450.017
Yeast
regulation of nervous system developmentGO:00519602480.017
meiotic cell cycle processGO:19030461320.017
positive regulation of macromolecule biosynthetic processGO:00105572830.017
positive regulation of cysteine type endopeptidase activityGO:2001056240.017
cell migrationGO:00164772380.017
protein depolymerizationGO:0051261310.016
regulation of anatomical structure morphogenesisGO:00226032420.016
compound eye developmentGO:00487493070.016
regulation of gene expression epigeneticGO:00400291280.016
Yeast
cytoplasmic transportGO:00164821300.016
protein maturationGO:0051604710.016
regulation of neurogenesisGO:00507671580.016
nucleoside catabolic processGO:00091641120.016
Yeast
macromolecular complex disassemblyGO:0032984370.016
glycosyl compound metabolic processGO:19016571270.016
Yeast
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.016
positive regulation of response to stimulusGO:00485843230.016
protein complex biogenesisGO:00702712010.015
cellular protein localizationGO:00346131600.015
glycosyl compound catabolic processGO:19016581120.015
Yeast
appendage developmentGO:00487364010.015
regulation of transportGO:00510491810.015
sister chromatid cohesionGO:0007062180.015
purine ribonucleoside triphosphate catabolic processGO:00092071080.015
Yeast
purine nucleoside triphosphate metabolic processGO:00091441190.015
Yeast
ribonucleoside triphosphate catabolic processGO:00092031080.015
Yeast
developmental growthGO:00485892800.015
carbohydrate derivative metabolic processGO:19011352170.015
Yeast
response to lipopolysaccharideGO:003249640.015
negative regulation of mitotic cell cycle phase transitionGO:19019911030.015
purine nucleoside triphosphate catabolic processGO:00091461080.014
Yeast
positive regulation of phosphate metabolic processGO:00459371390.014
regulation of gene silencingGO:0060968630.014
regulation of localizationGO:00328792750.014
regulation of gtpase activityGO:0043087440.014
organophosphate catabolic processGO:00464341120.014
Yeast
cell motilityGO:00488702510.014
negative regulation of meiotic cell cycleGO:005144720.014
regulation of developmental growthGO:00486381740.013
purine ribonucleoside monophosphate metabolic processGO:0009167500.013
Yeast
regulation of endopeptidase activityGO:0052548360.013
nucleotide metabolic processGO:00091171610.013
Yeast
phagocytosisGO:00069092150.013
nucleoside monophosphate metabolic processGO:0009123520.013
Yeast
sister chromatid segregationGO:0000819920.013
positive regulation of gtpase activityGO:0043547430.013
regulation of g1 s transition of mitotic cell cycleGO:2000045230.013
positive regulation of transcription dna templatedGO:00458932660.013
cellular macromolecular complex assemblyGO:00346221530.012
Yeast
positive regulation of signal transductionGO:00099672230.012
regulation of immune system processGO:00026821760.012
ribonucleotide metabolic processGO:00092591450.012
Yeast
single organism behaviorGO:00447083910.012
regulation of hydrolase activityGO:0051336970.012
telomere organizationGO:0032200210.012
negative regulation of multicellular organismal processGO:00512411420.012
gtp catabolic processGO:0006184720.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
Yeast
regulation of notch signaling pathwayGO:00085931000.012
response to organic substanceGO:00100332840.011
protein transportGO:00150311550.011
negative regulation of cell deathGO:0060548810.011
reproductive structure developmentGO:0048608740.011
Worm
positive regulation of cellular biosynthetic processGO:00313283160.011
negative regulation of microtubule depolymerizationGO:0007026210.011
purine nucleotide catabolic processGO:00061951090.011
Yeast
snrna metabolic processGO:0016073140.011
meiotic chromosome separationGO:005130780.011
positive regulation of multicellular organismal processGO:00512401430.011
nucleoside metabolic processGO:00091161270.011
Yeast
negative regulation of chromatin silencingGO:003193690.011
neurological system processGO:00508773580.011
regulation of proteolysisGO:0030162870.011
cellular amino acid metabolic processGO:0006520610.010
defense responseGO:00069523000.010
regulation of cell projection organizationGO:0031344920.010
negative regulation of developmental processGO:00510932010.010
covalent chromatin modificationGO:00165691060.010
negative regulation of cellular catabolic processGO:0031330340.010
regulation of chromatin organizationGO:1902275320.010
proteolysisGO:00065081920.010

Mcm3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
organ system cancerDOID:005068600.012
nervous system diseaseDOID:86300.011