Drosophila melanogaster

98 known processes

sl (Dmel_CG4200)

small wing

(Aliases: PLC-gamma D,Plcgamma,PLCgamma,plc-gammad,CG4200,PLCgammaDmel,Dmel\CG4200,PLC,PLC-gammaD,p145,PLC-gamma)

sl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleoside triphosphate metabolic processGO:00091411200.451
catabolic processGO:00090564090.293
small molecule metabolic processGO:00442813050.265
Mouse Rat
establishment of localization in cellGO:00516494020.263
Human Mouse Rat
intracellular transportGO:00469072280.228
Human Mouse
cell proliferationGO:00082832990.215
imaginal disc derived appendage developmentGO:00487373990.179
nucleoside triphosphate catabolic processGO:00091431080.173
organophosphate metabolic processGO:00196371950.152
Human Mouse Rat
regulation of organelle organizationGO:00330431960.141
ribonucleoside metabolic processGO:00091191270.137
purine ribonucleoside metabolic processGO:00461281270.127
nucleoside metabolic processGO:00091161270.127
tube developmentGO:00352952440.125
purine containing compound metabolic processGO:00725211550.123
cellular catabolic processGO:00442483720.122
embryonic morphogenesisGO:00485982060.120
cellular amino acid metabolic processGO:0006520610.114
purine nucleoside triphosphate metabolic processGO:00091441190.113
digestive tract morphogenesisGO:00485461270.110
phosphorylationGO:00163102940.109
cellular protein modification processGO:00064644380.109
positive regulation of nitrogen compound metabolic processGO:00511733540.106
regulation of molecular functionGO:00650092170.103
Mouse Rat
regulation of phosphate metabolic processGO:00192202100.102
purine nucleoside metabolic processGO:00422781270.098
ribonucleoside catabolic processGO:00424541120.097
purine ribonucleoside triphosphate metabolic processGO:00092051190.097
negative regulation of cellular metabolic processGO:00313243820.095
guanosine containing compound metabolic processGO:1901068740.095
organic substance transportGO:00717022570.094
Rat
purine nucleoside catabolic processGO:00061521120.094
determination of adult lifespanGO:00083401370.093
ribonucleotide metabolic processGO:00092591450.093
gtp metabolic processGO:0046039720.092
organonitrogen compound catabolic processGO:19015651280.092
digestive system developmentGO:00551231490.091
regulation of cellular catabolic processGO:00313291570.090
appendage developmentGO:00487364010.090
single organism catabolic processGO:00447122280.089
cell divisionGO:00513012480.088
purine nucleotide catabolic processGO:00061951090.085
tube morphogenesisGO:00352391910.085
organonitrogen compound metabolic processGO:19015643180.084
positive regulation of macromolecule biosynthetic processGO:00105572830.082
positive regulation of proteolysisGO:0045862520.082
cellularizationGO:0007349900.082
single organism biosynthetic processGO:00447112060.081
Human Mouse Rat
oxoacid metabolic processGO:00434361030.081
nucleobase containing small molecule metabolic processGO:00550861740.081
protein modification processGO:00362114380.080
negative regulation of nucleobase containing compound metabolic processGO:00459342610.080
organic acid metabolic processGO:00060821030.080
purine ribonucleotide catabolic processGO:00091541090.080
epithelial cell differentiationGO:00308553220.080
nuclear divisionGO:00002803320.077
regulation of cellular ketone metabolic processGO:001056530.076
purine nucleotide metabolic processGO:00061631460.075
response to organic substanceGO:00100332840.075
endocytosisGO:00068973100.073
protein modification by small protein conjugationGO:0032446790.073
regulation of cellular amino acid metabolic processGO:000652100.072
protein localizationGO:00081042840.072
Rat
regulation of catabolic processGO:00098941700.072
negative regulation of gene expressionGO:00106293870.071
carbohydrate derivative metabolic processGO:19011352170.070
positive regulation of cellular catabolic processGO:0031331950.070
response to other organismGO:00517072930.070
Mouse
regulation of cell proliferationGO:00421271630.069
establishment or maintenance of cell polarityGO:00071631670.068
nucleoside phosphate catabolic processGO:19012921100.067
digestive tract developmentGO:00485651490.067
neuron projection guidanceGO:00974852410.067
carboxylic acid metabolic processGO:0019752920.066
protein modification by small protein conjugation or removalGO:00706471060.066
purine ribonucleoside catabolic processGO:00461301120.065
golgi organizationGO:0007030660.064
single organism intracellular transportGO:19025822070.064
Human Mouse
organonitrogen compound biosynthetic processGO:19015661170.064
nucleoside phosphate metabolic processGO:00067531620.061
regionalizationGO:00030024160.061
imaginal disc derived wing morphogenesisGO:00074763370.061
regulation of transcription from rna polymerase ii promoterGO:00063573780.061
wing disc morphogenesisGO:00074723440.060
positive regulation of cell migrationGO:003033520.059
Human Rat
regulation of multicellular organismal developmentGO:20000264140.059
Human Zebrafish
regulation of intracellular signal transductionGO:19025312360.059
endomembrane system organizationGO:00102561190.059
aromatic compound catabolic processGO:00194391660.058
vesicle mediated transportGO:00161923810.058
guanosine containing compound catabolic processGO:1901069740.057
positive regulation of molecular functionGO:00440931360.056
Mouse
appendage morphogenesisGO:00351073970.055
nucleoside catabolic processGO:00091641120.054
axonogenesisGO:00074092900.053
negative regulation of macromolecule biosynthetic processGO:00105582700.052
neuron recognitionGO:00080381010.051
eye developmentGO:00016543230.050
growthGO:00400073590.049
cell motilityGO:00488702510.048
regulation of phosphorus metabolic processGO:00511742100.048
organic substance catabolic processGO:19015753080.048
response to bacteriumGO:00096171980.047
Mouse
cell migrationGO:00164772380.047
purine nucleoside triphosphate catabolic processGO:00091461080.047
ribonucleotide catabolic processGO:00092611090.046
ras protein signal transductionGO:0007265880.045
cellular nitrogen compound catabolic processGO:00442701650.045
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.045
gtp catabolic processGO:0006184720.045
positive regulation of phosphate metabolic processGO:00459371390.045
positive regulation of cellular biosynthetic processGO:00313283160.045
chaeta developmentGO:0022416970.044
posttranscriptional regulation of gene expressionGO:00106081450.044
positive regulation of phosphorus metabolic processGO:00105621390.044
regulation of cellular component biogenesisGO:00440872010.044
negative regulation of cell differentiationGO:00455961430.043
ribose phosphate metabolic processGO:00196931450.043
negative regulation of nucleic acid templated transcriptionGO:19035072400.043
purine ribonucleoside triphosphate catabolic processGO:00092071080.043
organophosphate catabolic processGO:00464341120.042
positive regulation of cellular component organizationGO:00511301560.042
single organism cellular localizationGO:19025801800.042
ribonucleoside triphosphate catabolic processGO:00092031080.042
purine ribonucleotide metabolic processGO:00091501450.041
ribonucleoside triphosphate metabolic processGO:00091991190.040
regulation of protein metabolic processGO:00512462560.040
nucleotide metabolic processGO:00091171610.039
protein phosphorylationGO:00064681690.039
purine containing compound catabolic processGO:00725231120.039
regulation of developmental growthGO:00486381740.038
respiratory system developmentGO:00605412130.038
nucleobase containing compound catabolic processGO:00346551650.038
autophagyGO:00069141080.038
localization of cellGO:00516742570.037
cellular amine metabolic processGO:0044106120.037
imaginal disc derived appendage morphogenesisGO:00351143950.037
positive regulation of catabolic processGO:00098961050.036
positive regulation of organelle organizationGO:0010638650.036
regulation of hydrolase activityGO:0051336970.036
multicellular organismal agingGO:00102591400.036
regulation of catalytic activityGO:00507901850.035
intracellular signal transductionGO:00355563000.035
Human
positive regulation of signalingGO:00230562430.035
positive regulation of biosynthetic processGO:00098913160.034
morphogenesis of an epitheliumGO:00020092760.033
positive regulation of cell motilityGO:200014730.033
Human Rat
positive regulation of nucleic acid templated transcriptionGO:19035082660.033
positive regulation of nucleobase containing compound metabolic processGO:00459353320.033
taxisGO:00423303040.033
transcription from rna polymerase ii promoterGO:00063663680.032
response to abiotic stimulusGO:00096283410.032
Rat
gastrulationGO:0007369700.032
negative regulation of biosynthetic processGO:00098902770.032
glycosyl compound metabolic processGO:19016571270.032
homeostatic processGO:00425921990.031
Human Mouse Rat
spermatogenesisGO:00072832000.031
regulation of receptor mediated endocytosisGO:004825990.031
cellular protein localizationGO:00346131600.030
positive regulation of multicellular organism growthGO:0040018210.030
proteolysisGO:00065081920.030
rna processingGO:00063961470.029
developmental growth involved in morphogenesisGO:0060560650.029
lipid metabolic processGO:00066291210.029
Human
stress activated mapk cascadeGO:0051403520.029
positive regulation of rna biosynthetic processGO:19026802660.029
response to biotic stimulusGO:00096072940.029
Mouse
transmembrane transportGO:00550851390.029
Mouse Rat
stem cell differentiationGO:00488631170.029
Zebrafish
amine metabolic processGO:0009308120.029
sex differentiationGO:0007548810.029
signal transduction by phosphorylationGO:00230141070.029
organic cyclic compound catabolic processGO:19013611680.028
immune responseGO:00069552460.028
Mouse
negative regulation of developmental growthGO:0048640640.028
positive regulation of signal transductionGO:00099672230.028
regulation of cellular protein metabolic processGO:00322682430.028
negative regulation of transcription dna templatedGO:00458922370.028
positive regulation of immune system processGO:0002684680.028
Mouse
body morphogenesisGO:001017120.028
positive regulation of catalytic activityGO:00430851180.027
positive regulation of cell communicationGO:00106472500.027
cell growthGO:00160491080.027
cell deathGO:00082192790.027
Mouse
g protein coupled receptor signaling pathwayGO:00071861360.027
cell recognitionGO:00080371020.027
carbohydrate derivative catabolic processGO:19011361180.026
lateral inhibitionGO:00463312060.026
regulation of mapk cascadeGO:0043408920.026
response to oxygen containing compoundGO:19017002000.026
central nervous system developmentGO:00074172010.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.026
defense responseGO:00069523000.025
negative regulation of cell communicationGO:00106482230.025
response to external biotic stimulusGO:00432072930.025
Mouse
organelle fissionGO:00482853400.025
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.025
axon developmentGO:00615642970.025
ncrna metabolic processGO:0034660430.025
inositol lipid mediated signalingGO:004801740.025
cellular macromolecule localizationGO:00707272200.025
negative regulation of rna biosynthetic processGO:19026792400.025
gastrulation with mouth forming firstGO:0001703360.025
asymmetric protein localizationGO:0008105330.025
ovarian follicle cell developmentGO:00307072480.024
negative regulation of nitrogen compound metabolic processGO:00511722650.024
segmentationGO:00352822070.024
ion transportGO:00068111450.024
Human Mouse Rat
macromolecular complex assemblyGO:00650032560.024
jnk cascadeGO:0007254500.024
genital disc developmentGO:0035215440.024
mesenchymal cell differentiationGO:004876210.024
cellular ketone metabolic processGO:0042180240.024
cellular amide metabolic processGO:0043603800.024
gland developmentGO:00487321910.023
immune response activating signal transductionGO:000275720.023
Mouse
post embryonic appendage morphogenesisGO:00351203850.023
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.023
stress activated protein kinase signaling cascadeGO:0031098550.023
reproductive structure developmentGO:0048608740.023
forebrain developmentGO:003090020.022
regulation of cell cycleGO:00517262910.022
muscle cell differentiationGO:00426921030.022
regulation of cell sizeGO:0008361630.022
chemotaxisGO:00069352490.022
developmental growthGO:00485892800.021
Zebrafish
synapse organizationGO:00508081960.021
response to light stimulusGO:00094161240.021
mesenchymal cell developmentGO:001403110.021
notch signaling pathwayGO:00072191200.021
spermatid developmentGO:0007286980.021
rna localizationGO:00064031150.021
asymmetric neuroblast divisionGO:0055059330.020
cellular response to oxygen containing compoundGO:1901701790.020
positive regulation of hydrolase activityGO:0051345780.020
negative regulation of molecular functionGO:0044092510.020
regulation of response to external stimulusGO:00321011150.020
cellular homeostasisGO:0019725800.020
Human Mouse Rat
regulation of protein modification processGO:00313991120.020
cytoplasmic transportGO:00164821300.020
Human Mouse
eye morphogenesisGO:00485922600.020
columnar cuboidal epithelial cell developmentGO:00020662490.020
response to nitrogen compoundGO:1901698900.020
cell migration involved in gastrulationGO:004207490.020
nitrogen compound transportGO:0071705850.020
spermatid differentiationGO:00485151140.019
regulation of cellular amine metabolic processGO:003323830.019
heterocycle catabolic processGO:00467001660.019
positive regulation of protein metabolic processGO:00512471280.019
proteasomal protein catabolic processGO:0010498590.019
immune effector processGO:0002252980.019
Mouse
phagocytosisGO:00069092150.019
dorsal ventral pattern formationGO:00099531330.019
intracellular protein transportGO:00068861040.019
sensory organ morphogenesisGO:00905962600.019
oocyte anterior posterior axis specificationGO:0007314720.019
immune system processGO:00023763470.019
Zebrafish Mouse
leg disc developmentGO:0035218920.019
single organism behaviorGO:00447083910.019
mapk cascadeGO:00001651070.018
synaptic target recognitionGO:0008039450.018
male gamete generationGO:00482322010.018
chemosensory behaviorGO:00076351060.018
cellular response to chemical stimulusGO:00708871990.018
Human
positive regulation of developmental processGO:00510941430.018
Human
cell adhesionGO:00071551360.018
positive regulation of intracellular transportGO:0032388420.018
Human
regulation of anatomical structure morphogenesisGO:00226032420.018
Human Zebrafish
regulation of establishment of protein localizationGO:0070201610.018
cell fate specificationGO:0001708710.018
regulation of stress activated mapk cascadeGO:0032872410.018
response to radiationGO:00093141550.018
nucleocytoplasmic transportGO:0006913720.018
regulation of multicellular organism growthGO:0040014400.018
regulation of cell cycle processGO:00105641810.018
blastoderm segmentationGO:00073501590.018
regulation of cellular component sizeGO:0032535980.017
salivary gland developmentGO:00074311620.017
reproductive system developmentGO:0061458740.017
protein ubiquitinationGO:0016567700.017
organelle assemblyGO:00709251980.017
compound eye developmentGO:00487493070.017
regulation of gtpase activityGO:0043087440.017
positive regulation of cellular protein metabolic processGO:00322701180.017
negative regulation of response to stimulusGO:00485852580.017
organelle localizationGO:00516401480.017
regulation of intracellular transportGO:0032386640.017
Human
protein complex assemblyGO:00064612000.017
positive regulation of phosphorylationGO:0042327870.017
positive regulation of transcription dna templatedGO:00458932660.017
actin cytoskeleton organizationGO:00300362060.017
regulation of gtp catabolic processGO:0033124440.017
positive regulation of gene expressionGO:00106282900.017
humoral immune responseGO:00069591170.017
stem cell developmentGO:0048864790.016
positive regulation of macromolecule metabolic processGO:00106044050.016
establishment of protein localizationGO:00451841630.016
Rat
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.016
ribonucleoprotein complex subunit organizationGO:0071826280.016
developmental cell growthGO:0048588520.016
positive regulation of response to stimulusGO:00485843230.016
Mouse
chorion containing eggshell formationGO:00073041050.016
regulation of localizationGO:00328792750.016
Human Zebrafish Mouse Rat
negative regulation of rna metabolic processGO:00512532510.016
regulation of phosphorylationGO:00423251470.016
chromatin modificationGO:00165681470.016
small gtpase mediated signal transductionGO:0007264880.016
dna metabolic processGO:00062592270.015
response to organonitrogen compoundGO:0010243750.015
regulation of synapse organizationGO:00508071100.015
vesicle fusionGO:0006906190.015
negative regulation of nervous system developmentGO:0051961920.015
negative regulation of growthGO:0045926840.015
epithelial cell developmentGO:00020642740.015
actomyosin structure organizationGO:0031032560.015
organelle fusionGO:0048284460.015
imaginal disc pattern formationGO:0007447910.015
actin filament based processGO:00300292200.015
protein localization to organelleGO:0033365820.015
compound eye morphogenesisGO:00017452490.015
phosphatidylinositol 3 kinase signalingGO:001406540.015
lipid homeostasisGO:0055088330.015
salivary gland morphogenesisGO:00074351450.015
regulation of nucleotide metabolic processGO:0006140620.015
muscle structure developmentGO:00610612240.015
neural precursor cell proliferationGO:0061351750.014
positive regulation of nucleotide catabolic processGO:0030813460.014
glycosyl compound catabolic processGO:19016581120.014
malpighian tubule developmentGO:0072002640.014
regulation of cellular localizationGO:00603411360.014
Human
regulation of purine nucleotide metabolic processGO:1900542620.014
negative regulation of multicellular organismal processGO:00512411420.014
olfactory behaviorGO:0042048970.014
negative regulation of cellular biosynthetic processGO:00313272770.014
regulation of growthGO:00400082330.014
negative regulation of developmental processGO:00510932010.014
response to glucoseGO:000974920.014
nucleotide catabolic processGO:00091661090.014
nucleobase containing compound transportGO:0015931560.013
regulation of vesicle mediated transportGO:0060627590.013
regulation of cell differentiationGO:00455953020.013
peptidyl amino acid modificationGO:00181931050.013
neuron projection extensionGO:1990138320.013
smoothened signaling pathwayGO:0007224490.013
ubiquitin dependent protein catabolic processGO:0006511780.013
imaginal disc derived wing vein morphogenesisGO:0008586440.013
regulation of epithelial cell differentiationGO:003085640.013
positive regulation of gtp catabolic processGO:0033126430.013
agingGO:00075681430.013
positive regulation of immune effector processGO:0002699280.013
regulation of protein localizationGO:0032880760.013
secretion by cellGO:00329401010.013
Rat
positive regulation of nucleoside metabolic processGO:0045979470.013
regulation of immune effector processGO:0002697520.013
regulation of programmed cell deathGO:00430671520.013
Mouse
membrane organizationGO:00610241120.013
ethanolamine containing compound metabolic processGO:004243940.013
regulation of immune system processGO:00026821760.013
Mouse
limb developmentGO:006017310.012
regulation of transportGO:00510491810.012
Human Mouse Rat
regulation of cell divisionGO:0051302720.012
tissue morphogenesisGO:00487292970.012
telencephalon developmentGO:002153720.012
positive regulation of receptor mediated endocytosisGO:004826070.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
response to organic cyclic compoundGO:0014070890.012
Rat
positive regulation of intracellular protein transportGO:0090316300.012
regulation of purine nucleotide catabolic processGO:0033121480.012
compound eye photoreceptor developmentGO:0042051780.012
regulation of response to stressGO:00801342000.012
stem cell divisionGO:0017145690.012
stem cell proliferationGO:0072089880.012
regulation of stress activated protein kinase signaling cascadeGO:0070302420.012
sensory perception of soundGO:0007605560.012
phosphatidylinositol mediated signalingGO:004801540.012
receptor mediated endocytosisGO:0006898210.012
posttranscriptional gene silencing by rnaGO:0035194450.012
biological adhesionGO:00226101380.012
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.012
regulation of autophagyGO:0010506620.012
activation of ras gtpase activityGO:003285660.012
posttranscriptional gene silencingGO:0016441460.012
positive regulation of protein transportGO:0051222370.012
regulation of cellular response to stressGO:0080135890.012
carbohydrate metabolic processGO:0005975820.012
developmental programmed cell deathGO:00106231380.012
positive regulation of protein localization to nucleusGO:1900182210.012
sperm individualizationGO:0007291480.011
wing disc pattern formationGO:0035222660.011
negative regulation of signalingGO:00230572190.011
regulation of anatomical structure sizeGO:00900661630.011
single organism membrane organizationGO:0044802930.011
chemical homeostasisGO:0048878920.011
Human Mouse Rat
response to peptide hormoneGO:0043434290.011
small molecule biosynthetic processGO:0044283370.011
Mouse Rat
kidney developmentGO:000182230.011
regulation of cell deathGO:00109411730.011
Mouse
cellular chemical homeostasisGO:0055082400.011
Human Mouse Rat
multi organism behaviorGO:00517051750.011
eye photoreceptor cell differentiationGO:00017541450.011
regulation of protein phosphorylationGO:0001932640.011
cellular macromolecular complex assemblyGO:00346221530.011
cellular response to dna damage stimulusGO:00069742230.011
maintenance of locationGO:0051235730.011
Human Mouse
cellular polysaccharide metabolic processGO:0044264110.011
head developmentGO:00603221350.011
modification dependent protein catabolic processGO:0019941780.011
macromolecule catabolic processGO:00090571610.011
protein complex biogenesisGO:00702712010.011
cellular response to nitrogen compoundGO:1901699510.011
regulation of endocytosisGO:0030100370.011
negative regulation of cellular protein metabolic processGO:0032269850.011
ion transmembrane transportGO:00342201220.011
Mouse Rat
camera type eye developmentGO:004301040.011
embryonic pattern specificationGO:00098801740.011
actin filament organizationGO:00070151260.010
cell fate determinationGO:0001709910.010
regulation of nucleoside metabolic processGO:0009118500.010
monocarboxylic acid transportGO:001571830.010
negative regulation of cell deathGO:0060548810.010
Mouse
protein heterooligomerizationGO:005129140.010
regulation of transferase activityGO:0051338580.010
connective tissue developmentGO:006144830.010
negative regulation of phosphorus metabolic processGO:0010563450.010
negative regulation of stress activated protein kinase signaling cascadeGO:0070303200.010
negative regulation of phosphate metabolic processGO:0045936450.010
leg disc morphogenesisGO:0007478800.010
epithelial tube morphogenesisGO:0060562880.010
regulation of ras protein signal transductionGO:0046578930.010
regulation of jnk cascadeGO:0046328400.010
axon guidanceGO:00074112330.010
regulation of apoptotic processGO:00429811300.010

sl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
musculoskeletal system diseaseDOID:1700.017
disease of metabolismDOID:001466700.015
nervous system diseaseDOID:86300.015
inherited metabolic disorderDOID:65500.011
cardiovascular system diseaseDOID:128700.011
sensory system diseaseDOID:005015500.010