Drosophila melanogaster

5 known processes

Tif-IA (Dmel_CG3278)

CG3278 gene product from transcript CG3278-RA

(Aliases: TifIA,CG3278,dTIF-IA,Dmel\CG3278,TIF-1A,Tif-1A,TIF-IA,CG16938,CG5951)

Tif-IA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell differentiationGO:00455953020.749
positive regulation of biosynthetic processGO:00098913160.490
Mouse
protein localizationGO:00081042840.473
cellular macromolecule localizationGO:00707272200.424
single organism cellular localizationGO:19025801800.402
cardiovascular system developmentGO:0072358820.372
establishment of localization in cellGO:00516494020.273
protein transportGO:00150311550.258
protein complex biogenesisGO:00702712010.239
Mouse
nuclear transportGO:0051169720.216
positive regulation of rna biosynthetic processGO:19026802660.198
Mouse
protein targetingGO:0006605640.181
positive regulation of macromolecule metabolic processGO:00106044050.179
Mouse
establishment of protein localizationGO:00451841630.156
intracellular transportGO:00469072280.152
positive regulation of rna metabolic processGO:00512542710.140
Mouse
cellular protein localizationGO:00346131600.137
single organism intracellular transportGO:19025822070.132
positive regulation of cellular protein metabolic processGO:00322701180.121
organic substance transportGO:00717022570.118
eye developmentGO:00016543230.113
cytoplasmic transportGO:00164821300.111
cytoplasm organizationGO:0007028640.108
Mouse
muscle cell differentiationGO:00426921030.106
positive regulation of nucleic acid templated transcriptionGO:19035082660.106
Mouse
eye morphogenesisGO:00485922600.089
cellular protein complex assemblyGO:0043623710.085
compound eye morphogenesisGO:00017452490.080
nuclear exportGO:0051168240.079
multicellular organism growthGO:0035264460.073
macromolecular complex assemblyGO:00650032560.073
Mouse
nucleocytoplasmic transportGO:0006913720.067
larval developmentGO:00021641040.066
single organism membrane organizationGO:0044802930.065
protein complex assemblyGO:00064612000.061
Mouse
establishment of protein localization to organelleGO:0072594620.061
cell deathGO:00082192790.059
Mouse
hemopoiesisGO:0030097460.058
positive regulation of nucleobase containing compound metabolic processGO:00459353320.058
Mouse
deathGO:00162652840.055
Mouse
programmed cell deathGO:00125012570.055
Mouse
mitochondrion organizationGO:0007005650.054
positive regulation of cellular biosynthetic processGO:00313283160.052
Mouse
protein localization to organelleGO:0033365820.052
developmental growthGO:00485892800.052
apoptotic processGO:00069151590.050
Mouse
gland developmentGO:00487321910.050
regulation of multicellular organismal developmentGO:20000264140.049
translationGO:0006412690.048
positive regulation of nitrogen compound metabolic processGO:00511733540.047
Mouse
positive regulation of macromolecule biosynthetic processGO:00105572830.046
Mouse
regulation of cell proliferationGO:00421271630.046
regulation of nervous system developmentGO:00519602480.043
regulation of programmed cell deathGO:00430671520.043
Mouse
regulation of apoptotic processGO:00429811300.042
Mouse
stem cell maintenanceGO:0019827670.042
embryo development ending in birth or egg hatchingGO:00097921520.040
Mouse
positive regulation of protein metabolic processGO:00512471280.038
hematopoietic or lymphoid organ developmentGO:0048534570.037
phagocytosisGO:00069092150.036
exocrine system developmentGO:00352721620.035
regulation of cellular protein metabolic processGO:00322682430.034
compound eye developmentGO:00487493070.034
immune system processGO:00023763470.033
regulation of localizationGO:00328792750.033
vesicle mediated transportGO:00161923810.033
gland morphogenesisGO:00226121450.033
rrna processingGO:000636430.032
sensory organ morphogenesisGO:00905962600.031
positive regulation of gene expressionGO:00106282900.029
Mouse
morphogenesis of an epitheliumGO:00020092760.029
nuclear importGO:0051170510.029
cellular component disassemblyGO:0022411460.028
negative regulation of signal transduction by p53 class mediatorGO:190179710.028
Mouse
stem cell divisionGO:0017145690.028
membrane organizationGO:00610241120.027
stem cell developmentGO:0048864790.027
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.027
Mouse
ribonucleoprotein complex disassemblyGO:003298810.026
protein modification processGO:00362114380.026
cellular macromolecular complex assemblyGO:00346221530.026
g2 dna damage checkpointGO:0031572690.024
regulation of meiosisGO:004002030.024
positive regulation of cell growthGO:0030307190.024
positive regulation of response to stimulusGO:00485843230.024
reproductive behaviorGO:00190981220.023
growthGO:00400073590.023
regulation of immune system processGO:00026821760.023
chromatin modificationGO:00165681470.023
proteolysisGO:00065081920.022
ribonucleoprotein complex biogenesisGO:0022613310.022
regulation of growthGO:00400082330.021
body morphogenesisGO:001017120.021
positive regulation of translationGO:0045727120.021
salivary gland morphogenesisGO:00074351450.021
asymmetric stem cell divisionGO:0098722490.021
positive regulation of developmental growthGO:0048639620.021
multicellular organismal agingGO:00102591400.020
rna processingGO:00063961470.020
actin filament organizationGO:00070151260.020
cellular macromolecule catabolic processGO:00442651360.020
intracellular protein transportGO:00068861040.020
protein ubiquitinationGO:0016567700.019
regulation of organelle organizationGO:00330431960.019
regulation of protein metabolic processGO:00512462560.019
neural retina developmentGO:000340740.018
regulation of hemocyte proliferationGO:0035206370.018
circulatory system developmentGO:0072359820.017
single organism nuclear importGO:1902593510.017
regulation of oocyte developmentGO:0060281270.017
cellular protein modification processGO:00064644380.016
rna catabolic processGO:0006401370.016
gene silencing by mirnaGO:0035195220.016
intermediate filament based processGO:004510310.016
response to external biotic stimulusGO:00432072930.016
salivary gland developmentGO:00074311620.015
salivary gland histolysisGO:0035070880.015
regulation of developmental growthGO:00486381740.015
negative regulation of gene expressionGO:00106293870.015
cellular amine metabolic processGO:0044106120.014
negative regulation of developmental processGO:00510932010.014
mitotic cell cycle phase transitionGO:00447721380.014
protein importGO:0017038550.014
regulation of phosphorus metabolic processGO:00511742100.014
regulation of cell cycle processGO:00105641810.014
regulation of translationGO:0006417560.013
translational terminationGO:000641520.013
intermediate filament cytoskeleton organizationGO:004510410.013
nuclear divisionGO:00002803320.013
immune system developmentGO:0002520570.013
mrna metabolic processGO:00160711240.013
negative regulation of phosphatase activityGO:001092330.013
regulation of histone methylationGO:0031060100.012
protein export from nucleusGO:0006611100.012
cellular catabolic processGO:00442483720.012
protein modification by small protein conjugation or removalGO:00706471060.012
photoreceptor cell differentiationGO:00465301700.012
positive regulation of multicellular organismal processGO:00512401430.012
homeostatic processGO:00425921990.011
Mouse
mrna polyadenylationGO:0006378110.011
establishment of organelle localizationGO:00516561220.011
locomotory behaviorGO:00076261760.011
protein targeting to nucleusGO:0044744510.011
macromolecule catabolic processGO:00090571610.011
regulation of protein modification processGO:00313991120.011
phosphorylationGO:00163102940.011
negative regulation of growthGO:0045926840.011
defense response to gram negative bacteriumGO:0050829940.011
organelle localizationGO:00516401480.011
regulation of signal transduction by p53 class mediatorGO:190179610.010
Mouse
multi organism reproductive behaviorGO:00447051210.010
pole plasm oskar mrna localizationGO:0045451460.010
positive regulation of molecular functionGO:00440931360.010
positive regulation of viral processGO:004852420.010

Tif-IA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
osteogenesis imperfectaDOID:1234700.023
disease of anatomical entityDOID:700.023
bone diseaseDOID:008000100.023
musculoskeletal system diseaseDOID:1700.023
bone development diseaseDOID:008000600.023
connective tissue diseaseDOID:6500.023
osteochondrodysplasiaDOID:225600.023
syndromeDOID:22500.013
benign neoplasmDOID:006007200.010
disease of cellular proliferationDOID:1456600.010