IMP: Integrative Multi-species Prediction

Drosophila melanogaster

102 known processes

Su(var)2-10 (Dmel_CG8068)

Suppressor of variegation 2-10

(Aliases: dPIAS,i184,Suvar(2)10,Su(var)-10,zimp,Su-var(2)10,PIAS,ZimpA,CLOT2057,Su(Var)2-10,dpias,CG8068,Dpias,Dmel\CG8068,pias,DPIAS,ZimpB,ZIMP,l(2)03697)

Entrez: 35927
FLYBASE: FBgn0003612
UniProtKB: Q7KNF5
UniProtKB: Q9XYM5
UniProtKB: A1Z7Q1
UniProtKB: Q8IGK3
UniProtKB: Q5BIG7
UniProtKB: A1Z7P9
UniProtKB: A1Z7P8
UniProtKB: A1Z7P5
UniProtKB: A1Z7P7

Process Predictions
Disease Predictions

Su(var)2-10 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
chromosome organization	GO:0051276	360	0.990
epithelial cell development	GO:0002064	274	0.977
chromatin organization	GO:0006325	207	0.975
ovarian follicle cell development	GO:0030707	248	0.971
heterochromatin organization	GO:0070828	25	0.947
meiotic chromosome segregation	GO:0045132	59	0.944
meiotic cell cycle	GO:0051321	171	0.931
meiotic nuclear division	GO:0007126	151	0.906
negative regulation of rna biosynthetic process	GO:1902679	240	0.863	Human Mouse
negative regulation of biosynthetic process	GO:0009890	277	0.850	Human Mouse
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.838	Human Mouse
dna conformation change	GO:0071103	105	0.824
chromatin modification	GO:0016568	147	0.751
cell motility	GO:0048870	251	0.741
chromosome segregation	GO:0007059	157	0.701
nuclear division	GO:0000280	332	0.632
heterochromatin organization involved in chromatin silencing	GO:0070868	9	0.630
chromosome condensation	GO:0030261	41	0.624
sister chromatid segregation	GO:0000819	92	0.623
dna packaging	GO:0006323	91	0.621
epithelial cell migration	GO:0010631	148	0.609
negative regulation of developmental process	GO:0051093	201	0.573
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.561
chromatin silencing	GO:0006342	76	0.524
cellular response to dna damage stimulus	GO:0006974	223	0.520
cell proliferation	GO:0008283	299	0.516	Mouse
photoreceptor cell differentiation	GO:0046530	170	0.512
organic acid metabolic process	GO:0006082	103	0.496
negative regulation of cellular biosynthetic process	GO:0031327	277	0.493	Human Mouse
covalent chromatin modification	GO:0016569	106	0.458
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.446	Human Mouse
histone modification	GO:0016570	106	0.443
cell migration	GO:0016477	238	0.439
mitotic sister chromatid segregation	GO:0000070	87	0.438
dna metabolic process	GO:0006259	227	0.423
epithelium migration	GO:0090132	148	0.403
meiotic cell cycle process	GO:1903046	132	0.391
localization of cell	GO:0051674	257	0.385
chromatin assembly or disassembly	GO:0006333	52	0.372
positive regulation of gene expression	GO:0010628	290	0.332	Mouse
regulation of neurogenesis	GO:0050767	158	0.326
female meiotic division	GO:0007143	70	0.324
regulation of cell proliferation	GO:0042127	163	0.324	Mouse
immune system process	GO:0002376	347	0.317
embryonic organ development	GO:0048568	50	0.310
cell cycle checkpoint	GO:0000075	95	0.294
regulation of cell differentiation	GO:0045595	302	0.293	Mouse
regulation of protein metabolic process	GO:0051246	256	0.291	Human Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.285	Mouse
ovarian follicle cell migration	GO:0007297	121	0.283
regulation of neuron differentiation	GO:0045664	103	0.276
catabolic process	GO:0009056	409	0.271	Mouse
eye photoreceptor cell differentiation	GO:0001754	145	0.266
cellular protein modification process	GO:0006464	438	0.262	Human Mouse Worm
response to organic cyclic compound	GO:0014070	89	0.260
epithelial cell differentiation	GO:0030855	322	0.255
response to external biotic stimulus	GO:0043207	293	0.254
negative regulation of neurogenesis	GO:0050768	53	0.253
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.253	Human Mouse
transcription from rna polymerase ii promoter	GO:0006366	368	0.252	Mouse
macromolecular complex assembly	GO:0065003	256	0.241
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.238	Mouse
regulation of gene silencing	GO:0060968	63	0.234
gliogenesis	GO:0042063	80	0.227
organelle fission	GO:0048285	340	0.224
negative regulation of transcription dna templated	GO:0045892	237	0.223	Human Mouse
gene silencing	GO:0016458	138	0.221
rhythmic process	GO:0048511	106	0.215
regulation of chromatin silencing	GO:0031935	36	0.213
growth	GO:0040007	359	0.211	Worm
spindle organization	GO:0007051	253	0.199
cellular response to chemical stimulus	GO:0070887	199	0.193
regulation of cellular amino acid metabolic process	GO:0006521	0	0.192
chromatin assembly	GO:0031497	48	0.190
cellular ketone metabolic process	GO:0042180	24	0.187
regulation of localization	GO:0032879	275	0.186
germ line cyst formation	GO:0048134	44	0.185
establishment of localization in cell	GO:0051649	402	0.184
border follicle cell migration	GO:0007298	113	0.184
columnar cuboidal epithelial cell development	GO:0002066	249	0.183
negative regulation of cell differentiation	GO:0045596	143	0.180
intracellular receptor signaling pathway	GO:0030522	19	0.178
regulation of chromosome organization	GO:0033044	64	0.177
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.177	Human Mouse
nucleosome mobilization	GO:0042766	9	0.175
stem cell maintenance	GO:0019827	67	0.172
cell death	GO:0008219	279	0.171	Mouse
negative regulation of cellular metabolic process	GO:0031324	382	0.168	Human Mouse
positive regulation of multicellular organismal process	GO:0051240	143	0.164	Worm
larval development	GO:0002164	104	0.161	Worm
regulation of cellular localization	GO:0060341	136	0.160
regulation of organelle organization	GO:0033043	196	0.158
axon development	GO:0061564	297	0.155
positive regulation of rna metabolic process	GO:0051254	271	0.149	Mouse
modification dependent protein catabolic process	GO:0019941	78	0.146	Mouse
defense response to other organism	GO:0098542	225	0.142
sex differentiation	GO:0007548	81	0.142	Worm
negative regulation of rna metabolic process	GO:0051253	251	0.140	Human Mouse
positive regulation of developmental process	GO:0051094	143	0.135	Worm
mitotic chromosome condensation	GO:0007076	22	0.133
chromatin remodeling	GO:0006338	72	0.132
cellular protein catabolic process	GO:0044257	83	0.132	Mouse
response to other organism	GO:0051707	293	0.129
regulation of cellular catabolic process	GO:0031329	157	0.129	Mouse
atp metabolic process	GO:0046034	49	0.129
protein maturation	GO:0051604	71	0.125
internal peptidyl lysine acetylation	GO:0018393	38	0.124
regulation of cellular ketone metabolic process	GO:0010565	3	0.120
regulation of transcription by chromatin organization	GO:0034401	3	0.120
vesicle mediated transport	GO:0016192	381	0.118
single organism catabolic process	GO:0044712	228	0.117
axonogenesis	GO:0007409	290	0.115
nucleosome organization	GO:0034728	59	0.112
body morphogenesis	GO:0010171	2	0.110	Worm
regulation of cellular protein metabolic process	GO:0032268	243	0.108	Human Mouse
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.105	Mouse
negative regulation of gene expression	GO:0010629	387	0.105	Human Mouse
regulation of photoreceptor cell differentiation	GO:0046532	34	0.104
regulation of nuclear division	GO:0051783	58	0.104
regionalization	GO:0003002	416	0.104
dna replication	GO:0006260	48	0.104
production of sirna involved in rna interference	GO:0030422	11	0.103
regulation of meiosis	GO:0040020	3	0.102
sensory organ morphogenesis	GO:0090596	260	0.101
negative regulation of chromosome organization	GO:2001251	19	0.100
mitotic sister chromatid separation	GO:0051306	30	0.098
regulation of chromatin organization	GO:1902275	32	0.097
small molecule metabolic process	GO:0044281	305	0.096
nucleosome positioning	GO:0016584	3	0.094
peptidyl amino acid modification	GO:0018193	105	0.093
regulation of cellular component biogenesis	GO:0044087	201	0.093
nucleotide metabolic process	GO:0009117	161	0.091
negative regulation of multicellular organismal process	GO:0051241	142	0.090
immune response	GO:0006955	246	0.087
regulation of cell cycle	GO:0051726	291	0.086
positive regulation of cellular amine metabolic process	GO:0033240	0	0.086
regulation of molecular function	GO:0065009	217	0.083	Mouse
positive regulation of catabolic process	GO:0009896	105	0.081	Mouse
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.080	Mouse
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.079	Mouse
compound eye morphogenesis	GO:0001745	249	0.079
response to biotic stimulus	GO:0009607	294	0.079
positive regulation of cell communication	GO:0010647	250	0.078	Mouse
cellular amino acid metabolic process	GO:0006520	61	0.076
regulation of phosphate metabolic process	GO:0019220	210	0.075
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.072
regulation of proteasomal protein catabolic process	GO:0061136	39	0.071	Mouse
protein processing	GO:0016485	68	0.071
positive regulation of biosynthetic process	GO:0009891	316	0.071	Mouse
protein dna complex subunit organization	GO:0071824	86	0.070
response to sterol	GO:0036314	34	0.070
oocyte maturation	GO:0001556	3	0.069
regulation of nervous system development	GO:0051960	248	0.069
positive regulation of rna biosynthetic process	GO:1902680	266	0.068	Mouse
nucleoside metabolic process	GO:0009116	127	0.068
regulation of cellular amine metabolic process	GO:0033238	3	0.068
positive regulation of neurogenesis	GO:0050769	41	0.068
carboxylic acid metabolic process	GO:0019752	92	0.065
histone acetylation	GO:0016573	38	0.064
negative regulation of organelle organization	GO:0010639	56	0.063
proteasomal protein catabolic process	GO:0010498	59	0.063	Mouse
carbohydrate derivative catabolic process	GO:1901136	118	0.063
female meiosis chromosome segregation	GO:0016321	33	0.063
negative regulation of neuroblast proliferation	GO:0007406	27	0.063
regulation of cytoplasmic transport	GO:1903649	47	0.063
eye morphogenesis	GO:0048592	260	0.063
immune system development	GO:0002520	57	0.061
negative regulation of nervous system development	GO:0051961	92	0.061
regulation of cell development	GO:0060284	215	0.060
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.060
organic substance catabolic process	GO:1901575	308	0.060	Mouse
organophosphate metabolic process	GO:0019637	195	0.059
positive regulation of cellular biosynthetic process	GO:0031328	316	0.059	Mouse
regulation of protein localization	GO:0032880	76	0.059
phagocytosis	GO:0006909	215	0.058
regulation of developmental growth	GO:0048638	174	0.057	Worm
compound eye photoreceptor cell differentiation	GO:0001751	140	0.057
fatty acid homeostasis	GO:0055089	2	0.056
dorsal ventral pattern formation	GO:0009953	133	0.056
negative regulation of protein metabolic process	GO:0051248	85	0.054
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.053	Human Mouse
regulation of cell division	GO:0051302	72	0.052
positive regulation of macromolecule metabolic process	GO:0010604	405	0.052	Human Mouse
apical constriction	GO:0003383	18	0.051
dendrite morphogenesis	GO:0048813	199	0.051
purine nucleoside metabolic process	GO:0042278	127	0.051
positive regulation of transcription dna templated	GO:0045893	266	0.050	Mouse
nuclear transport	GO:0051169	72	0.049
posttranscriptional gene silencing	GO:0016441	46	0.049
mitotic nuclear division	GO:0007067	213	0.048
proteolysis	GO:0006508	192	0.048	Mouse
regulation of cellular response to stress	GO:0080135	89	0.048	Mouse
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.047
regulation of multicellular organism growth	GO:0040014	40	0.047	Worm
ribonucleotide metabolic process	GO:0009259	145	0.047
gland development	GO:0048732	191	0.047
intracellular transport	GO:0046907	228	0.046
response to ecdysone	GO:0035075	34	0.045
circadian rhythm	GO:0007623	105	0.045
negative regulation of cell proliferation	GO:0008285	69	0.045
mitotic spindle elongation	GO:0000022	81	0.045
negative regulation of cellular protein metabolic process	GO:0032269	85	0.044
production of small rna involved in gene silencing by rna	GO:0070918	15	0.044
ribonucleoside catabolic process	GO:0042454	112	0.044
protein modification process	GO:0036211	438	0.043	Human Mouse Worm
nucleoside phosphate metabolic process	GO:0006753	162	0.043
regulation of chromatin modification	GO:1903308	28	0.042
response to extracellular stimulus	GO:0009991	116	0.042
hemopoiesis	GO:0030097	46	0.042
stem cell differentiation	GO:0048863	117	0.041
positive regulation of proteolysis	GO:0045862	52	0.040	Mouse
tissue migration	GO:0090130	155	0.040
nucleoside phosphate catabolic process	GO:1901292	110	0.040
negative regulation of response to stimulus	GO:0048585	258	0.040
chromosome separation	GO:0051304	42	0.039
histone h4 k20 methylation	GO:0034770	4	0.039
response to ketone	GO:1901654	34	0.039
jak stat cascade	GO:0007259	49	0.038
olfactory behavior	GO:0042048	97	0.038
molting cycle	GO:0042303	56	0.038
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.038
heterocycle catabolic process	GO:0046700	166	0.038
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.037
cellular protein localization	GO:0034613	160	0.037
negative regulation of gene expression epigenetic	GO:0045814	77	0.037
hematopoietic or lymphoid organ development	GO:0048534	57	0.037
homeostatic process	GO:0042592	199	0.036
amine metabolic process	GO:0009308	12	0.036
secretion by cell	GO:0032940	101	0.036
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.036
negative regulation of chromosome segregation	GO:0051985	14	0.036
regulation of catabolic process	GO:0009894	170	0.036	Mouse
regulation of protein transport	GO:0051223	57	0.036
purine ribonucleotide catabolic process	GO:0009154	109	0.035
regulation of multicellular organismal development	GO:2000026	414	0.035
ecdysone receptor mediated signaling pathway	GO:0035076	11	0.034
targeting of mrna for destruction involved in rna interference	GO:0030423	4	0.034
nucleoside catabolic process	GO:0009164	112	0.034
purine nucleoside catabolic process	GO:0006152	112	0.034
regulation of nucleocytoplasmic transport	GO:0046822	35	0.034
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.033
cytoplasmic transport	GO:0016482	130	0.033
nucleoside triphosphate catabolic process	GO:0009143	108	0.033
regulation of neuron projection development	GO:0010975	69	0.033
oxoacid metabolic process	GO:0043436	103	0.033
protein acetylation	GO:0006473	39	0.033
programmed cell death	GO:0012501	257	0.032	Mouse
defense response to bacterium	GO:0042742	178	0.032
organonitrogen compound metabolic process	GO:1901564	318	0.032
embryo development ending in birth or egg hatching	GO:0009792	152	0.031	Worm
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.031
organonitrogen compound catabolic process	GO:1901565	128	0.031
cellular catabolic process	GO:0044248	372	0.031	Mouse
tissue morphogenesis	GO:0048729	297	0.031
intracellular signal transduction	GO:0035556	300	0.030	Mouse
digestive tract morphogenesis	GO:0048546	127	0.030
chemosensory behavior	GO:0007635	106	0.030
regulation of transport	GO:0051049	181	0.029
ribonucleotide catabolic process	GO:0009261	109	0.029
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.029
negative regulation of cellular component organization	GO:0051129	108	0.029
negative regulation of meiotic cell cycle	GO:0051447	2	0.029
glycosyl compound metabolic process	GO:1901657	127	0.029
cellular macromolecule catabolic process	GO:0044265	136	0.028	Mouse
tube development	GO:0035295	244	0.028	Worm
purine nucleotide metabolic process	GO:0006163	146	0.027
regulation of mitotic cell cycle	GO:0007346	190	0.027
regulation of protein modification process	GO:0031399	112	0.027	Human
spermatid differentiation	GO:0048515	114	0.027
response to ionizing radiation	GO:0010212	32	0.027
reproductive structure development	GO:0048608	74	0.027	Worm
cellular nitrogen compound catabolic process	GO:0044270	165	0.027
regulation of growth	GO:0040008	233	0.027	Worm
positive regulation of cell cycle	GO:0045787	43	0.027
cellular macromolecular complex assembly	GO:0034622	153	0.027
salivary gland development	GO:0007431	162	0.026
humoral immune response	GO:0006959	117	0.026
positive regulation of organelle organization	GO:0010638	65	0.026
eye development	GO:0001654	323	0.026
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	16	0.026
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.026
post embryonic hemopoiesis	GO:0035166	17	0.026
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.026	Mouse
regulation of heterochromatin assembly	GO:0031445	8	0.025
eggshell formation	GO:0030703	105	0.025
modification dependent macromolecule catabolic process	GO:0043632	79	0.025	Mouse
determination of adult lifespan	GO:0008340	137	0.025
genitalia development	GO:0048806	26	0.025	Worm
regulation of proteolysis	GO:0030162	87	0.025	Mouse
regulation of metaphase anaphase transition of cell cycle	GO:1902099	26	0.025
purine containing compound metabolic process	GO:0072521	155	0.025
positive regulation of r7 cell differentiation	GO:0045678	7	0.024
positive regulation of mitotic sister chromatid separation	GO:1901970	10	0.024
nuclear import	GO:0051170	51	0.024
regulation of catalytic activity	GO:0050790	185	0.024
peptidyl lysine modification	GO:0018205	57	0.024
mitotic cell cycle embryonic	GO:0045448	38	0.024
cellular amine metabolic process	GO:0044106	12	0.024
multicellular organism growth	GO:0035264	46	0.024	Worm
positive regulation of transport	GO:0051050	92	0.024
neuron projection guidance	GO:0097485	241	0.024
purine ribonucleoside catabolic process	GO:0046130	112	0.024
photoreceptor cell development	GO:0042461	96	0.023
compound eye photoreceptor development	GO:0042051	78	0.023
regulation of cell cycle process	GO:0010564	181	0.023
oocyte differentiation	GO:0009994	145	0.023
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.023	Mouse
glycosyl compound catabolic process	GO:1901658	112	0.023
glial cell differentiation	GO:0010001	35	0.022
histone methylation	GO:0016571	40	0.022
regulation of neuroblast proliferation	GO:1902692	34	0.022
positive regulation of metaphase anaphase transition of cell cycle	GO:1902101	10	0.022
internal protein amino acid acetylation	GO:0006475	38	0.022
positive regulation of mitotic metaphase anaphase transition	GO:0045842	10	0.022
positive regulation of cell division	GO:0051781	16	0.022
aging	GO:0007568	143	0.021
regulation of chromatin binding	GO:0035561	3	0.021
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.021
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.021
multicellular organismal aging	GO:0010259	140	0.021
protein modification by small protein conjugation	GO:0032446	79	0.021	Human Mouse Worm
tricarboxylic acid metabolic process	GO:0072350	1	0.021
dendrite development	GO:0016358	204	0.021
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.021	Mouse
purine ribonucleotide metabolic process	GO:0009150	145	0.020
cellular response to organic cyclic compound	GO:0071407	32	0.020
positive regulation of molecular function	GO:0044093	136	0.020
cell cycle phase transition	GO:0044770	140	0.020
imaginal disc derived wing morphogenesis	GO:0007476	337	0.020
embryonic development via the syncytial blastoderm	GO:0001700	148	0.020
purine ribonucleoside metabolic process	GO:0046128	127	0.020
histone lysine demethylation	GO:0070076	6	0.020
regulation of intracellular protein transport	GO:0033157	46	0.019
regulation of meiotic cell cycle	GO:0051445	9	0.019
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.019
developmental growth	GO:0048589	280	0.019	Worm
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.019
response to wounding	GO:0009611	94	0.019
rna interference	GO:0016246	27	0.019
nucleoside monophosphate catabolic process	GO:0009125	39	0.019
atp dependent chromatin remodeling	GO:0043044	22	0.019
developmental maturation	GO:0021700	172	0.019
nucleobase containing compound catabolic process	GO:0034655	165	0.019
nucleotide catabolic process	GO:0009166	109	0.018
gonad morphogenesis	GO:0035262	7	0.018
methylation	GO:0032259	47	0.018
protein localization to chromatin	GO:0071168	3	0.018
forebrain development	GO:0030900	2	0.018
nucleobase containing small molecule metabolic process	GO:0055086	174	0.018
purine containing compound catabolic process	GO:0072523	112	0.018
regulation of gene expression epigenetic	GO:0040029	128	0.018
positive regulation of protein import into nucleus	GO:0042307	21	0.018
central nervous system development	GO:0007417	201	0.018
regulation of chromosome segregation	GO:0051983	32	0.018
centrosome duplication	GO:0051298	121	0.017
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.017	Mouse
response to alcohol	GO:0097305	95	0.017
nucleoside triphosphate metabolic process	GO:0009141	120	0.017
positive regulation of cellular protein metabolic process	GO:0032270	118	0.017	Human Mouse
protein import into nucleus	GO:0006606	51	0.017
carbohydrate derivative metabolic process	GO:1901135	217	0.017
purine nucleotide catabolic process	GO:0006195	109	0.017
regulation of intracellular transport	GO:0032386	64	0.017
positive regulation of signaling	GO:0023056	243	0.017	Mouse
endocytosis	GO:0006897	310	0.017
positive regulation of protein metabolic process	GO:0051247	128	0.017	Human Mouse
metaphase anaphase transition of cell cycle	GO:0044784	28	0.017
phosphorylation	GO:0016310	294	0.017
cellular response to organic substance	GO:0071310	132	0.017
nuclear body organization	GO:0030575	6	0.017
negative regulation of cell cycle process	GO:0010948	109	0.016
cellular response to lipopolysaccharide	GO:0071222	3	0.016
peptidyl lysine acetylation	GO:0018394	39	0.016
regulation of establishment of protein localization	GO:0070201	61	0.016
neural retina development	GO:0003407	4	0.016
cell fate specification	GO:0001708	71	0.016
regulation of cellular protein catabolic process	GO:1903362	44	0.016	Mouse
appendage morphogenesis	GO:0035107	397	0.016
defense response to fungus	GO:0050832	48	0.016
protein localization	GO:0008104	284	0.016
response to oxygen containing compound	GO:1901700	200	0.016
response to dsrna	GO:0043331	15	0.015
stem cell development	GO:0048864	79	0.015
female germ line cyst formation	GO:0048135	42	0.015
nucleoside monophosphate metabolic process	GO:0009123	52	0.015
single organism intracellular transport	GO:1902582	207	0.015
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.015
macromolecule methylation	GO:0043414	45	0.015
protein targeting	GO:0006605	64	0.015
leg disc morphogenesis	GO:0007478	80	0.015
histone h3 k9 acetylation	GO:0043970	3	0.015
cation transport	GO:0006812	110	0.015
inositol lipid mediated signaling	GO:0048017	4	0.015
intracellular steroid hormone receptor signaling pathway	GO:0030518	12	0.015
regulation of cell substrate adhesion	GO:0010810	2	0.015
regulation of cell cycle phase transition	GO:1901987	130	0.015
atp catabolic process	GO:0006200	38	0.015
establishment of protein localization to organelle	GO:0072594	62	0.014
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.014
response to organonitrogen compound	GO:0010243	75	0.014
chromosome localization	GO:0050000	20	0.014
positive regulation of developmental growth	GO:0048639	62	0.014	Worm
histolysis	GO:0007559	102	0.014
hindbrain development	GO:0030902	2	0.014
appendage development	GO:0048736	401	0.014
positive regulation of cell proliferation	GO:0008284	47	0.014
positive regulation of phosphate metabolic process	GO:0045937	139	0.014
single organism cellular localization	GO:1902580	180	0.014
establishment of tissue polarity	GO:0007164	87	0.013
mitotic dna damage checkpoint	GO:0044773	74	0.013
positive regulation of cellular component organization	GO:0051130	156	0.013
regulation of response to gamma radiation	GO:2001228	4	0.013
regulation of mitosis	GO:0007088	56	0.013
small gtpase mediated signal transduction	GO:0007264	88	0.013
regulation of intracellular signal transduction	GO:1902531	236	0.013	Mouse
organophosphate catabolic process	GO:0046434	112	0.013
cellular component maintenance	GO:0043954	23	0.013
nucleolus organization	GO:0007000	4	0.013
autophagic cell death	GO:0048102	83	0.013
oocyte construction	GO:0007308	112	0.013
mitotic spindle organization	GO:0007052	220	0.013
circadian regulation of gene expression	GO:0032922	5	0.013
positive regulation of cellular protein catabolic process	GO:1903364	24	0.013	Mouse
embryonic pattern specification	GO:0009880	174	0.013
negative regulation of response to gamma radiation	GO:2001229	4	0.013
spermatogenesis	GO:0007283	200	0.013
regulation of protein import into nucleus	GO:0042306	28	0.013
negative regulation of cell communication	GO:0010648	223	0.013
positive regulation of response to stimulus	GO:0048584	323	0.013
germarium derived female germ line cyst formation	GO:0030727	42	0.013
axon guidance	GO:0007411	233	0.013
negative regulation of protein maturation	GO:1903318	31	0.012
hindgut morphogenesis	GO:0007442	58	0.012
positive regulation of mitotic cell cycle	GO:0045931	34	0.012
regulation of embryonic cell shape	GO:0016476	30	0.012
actin mediated cell contraction	GO:0070252	21	0.012
male gamete generation	GO:0048232	201	0.012
negative regulation of chromatin modification	GO:1903309	5	0.012
posttranscriptional regulation of gene expression	GO:0010608	145	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.012
positive regulation of proteolysis involved in cellular protein catabolic process	GO:1903052	24	0.012	Mouse
tissue death	GO:0016271	102	0.012
pronuclear migration	GO:0035046	4	0.012
defense response	GO:0006952	300	0.012
single organism behavior	GO:0044708	391	0.012
regulation of cell adhesion	GO:0030155	27	0.012
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.012
regulation of translation	GO:0006417	56	0.012
chromatin maintenance	GO:0070827	2	0.012
positive regulation of atp catabolic process	GO:1903291	3	0.011
regulation of chromatin assembly	GO:0010847	9	0.011
regulation of mitotic metaphase anaphase transition	GO:0030071	26	0.011
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.011	Mouse
negative regulation of cell death	GO:0060548	81	0.011
negative regulation of signal transduction	GO:0009968	206	0.011
g2 dna damage checkpoint	GO:0031572	69	0.011
establishment of organelle localization	GO:0051656	122	0.011
regulation of response to stress	GO:0080134	200	0.011
protein polymerization	GO:0051258	42	0.011
positive regulation of signal transduction	GO:0009967	223	0.011	Mouse
regulation of defense response to virus by host	GO:0050691	10	0.011
gene silencing by rna	GO:0031047	57	0.011
instar larval development	GO:0002168	55	0.011
negative regulation of catabolic process	GO:0009895	36	0.011
positive regulation of cell cycle process	GO:0090068	28	0.011
associative learning	GO:0008306	65	0.011
imaginal disc derived appendage development	GO:0048737	399	0.010
regulation of dendrite morphogenesis	GO:0048814	28	0.010
cytokinetic cell separation	GO:0000920	1	0.010
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.010
negative regulation of photoreceptor cell differentiation	GO:0046533	8	0.010
cellular response to oxygen containing compound	GO:1901701	79	0.010

Su(var)2-10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.029
nervous system disease	DOID:863	0.017
sensory system disease	DOID:0050155	0.017

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