IMP: Integrative Multi-species Prediction

Drosophila melanogaster

56 known processes

Trim9 (Dmel_CG31721)

CG31721 gene product from transcript CG31721-RB

(Aliases: CG13145,Dmel\CG31721,CG31721,CG6256)

FLYBASE: FBgn0051721
Entrez: 34453
UniProtKB: Q86P21
UniProtKB: M9MRI4

Process Predictions
Disease Predictions

Trim9 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
axon development	GO:0061564	297	0.998
axon guidance	GO:0007411	233	0.981
axonogenesis	GO:0007409	290	0.955
regulation of dendrite morphogenesis	GO:0048814	28	0.932
taxis	GO:0042330	304	0.910
negative regulation of gene expression	GO:0010629	387	0.875
telencephalon development	GO:0021537	2	0.875
neuron recognition	GO:0008038	101	0.870
neuron projection guidance	GO:0097485	241	0.845
dendrite guidance	GO:0070983	21	0.843
dendrite self avoidance	GO:0070593	8	0.812
photoreceptor cell axon guidance	GO:0072499	23	0.779
forebrain development	GO:0030900	2	0.727
negative regulation of signaling	GO:0023057	219	0.703	Mouse
chemotaxis	GO:0006935	249	0.696
synapse assembly	GO:0007416	143	0.678
regulation of dendrite development	GO:0050773	37	0.602
head development	GO:0060322	135	0.599
cell recognition	GO:0008037	102	0.565
negative regulation of cell communication	GO:0010648	223	0.556	Mouse
stem cell differentiation	GO:0048863	117	0.552
axon midline choice point recognition	GO:0016199	26	0.534
dendrite development	GO:0016358	204	0.519
positive regulation of nervous system development	GO:0051962	69	0.497	Mouse
locomotory behavior	GO:0007626	176	0.496
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.485
ventral cord development	GO:0007419	16	0.480
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.457
regulation of cell differentiation	GO:0045595	302	0.454	Mouse
biological adhesion	GO:0022610	138	0.450
brain development	GO:0007420	120	0.444
cognition	GO:0050890	141	0.428
negative regulation of nervous system development	GO:0051961	92	0.421
regulation of axon extension involved in axon guidance	GO:0048841	4	0.398
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.395
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.386
cell cell adhesion	GO:0098609	26	0.383
dorsal ventral axon guidance	GO:0033563	2	0.379
central nervous system development	GO:0007417	201	0.379
regulation of cell projection organization	GO:0031344	92	0.350	Mouse
developmental growth involved in morphogenesis	GO:0060560	65	0.342
dendrite morphogenesis	GO:0048813	199	0.332
purine nucleoside metabolic process	GO:0042278	127	0.315
regulation of cellular protein metabolic process	GO:0032268	243	0.314	Mouse
positive regulation of response to stimulus	GO:0048584	323	0.313
negative regulation of transcription dna templated	GO:0045892	237	0.311
positive regulation of axonogenesis	GO:0050772	2	0.310
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.309
tissue morphogenesis	GO:0048729	297	0.305
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.303
cell motility	GO:0048870	251	0.299
cell migration	GO:0016477	238	0.286
olfactory learning	GO:0008355	56	0.285
negative regulation of cellular metabolic process	GO:0031324	382	0.285
negative regulation of developmental process	GO:0051093	201	0.275
learning or memory	GO:0007611	141	0.275
regulation of neuron differentiation	GO:0045664	103	0.264	Mouse
regulation of nervous system development	GO:0051960	248	0.260	Mouse
regulation of epithelial cell migration open tracheal system	GO:2000274	11	0.251
regulation of synapse organization	GO:0050807	110	0.243
regulation of synapse assembly	GO:0051963	94	0.243
regulation of protein metabolic process	GO:0051246	256	0.243	Mouse
synapse organization	GO:0050808	196	0.236
neural precursor cell proliferation	GO:0061351	75	0.233
purine ribonucleotide catabolic process	GO:0009154	109	0.230
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.218
positive regulation of developmental process	GO:0051094	143	0.214	Mouse
intracellular signal transduction	GO:0035556	300	0.212	Mouse
epithelial tube morphogenesis	GO:0060562	88	0.207
memory	GO:0007613	94	0.203
purine nucleotide metabolic process	GO:0006163	146	0.201
positive regulation of axon guidance	GO:1902669	1	0.195
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.194
organonitrogen compound metabolic process	GO:1901564	318	0.191
localization of cell	GO:0051674	257	0.184
protein modification process	GO:0036211	438	0.184	Mouse
purine containing compound metabolic process	GO:0072521	155	0.179
nucleoside metabolic process	GO:0009116	127	0.174
regulation of neuron projection development	GO:0010975	69	0.173	Mouse
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.171
negative regulation of cellular biosynthetic process	GO:0031327	277	0.167
negative regulation of growth	GO:0045926	84	0.165
carbohydrate derivative metabolic process	GO:1901135	217	0.165
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.165
post embryonic appendage morphogenesis	GO:0035120	385	0.164
positive regulation of cellular catabolic process	GO:0031331	95	0.162	Mouse
negative regulation of developmental growth	GO:0048640	64	0.158
negative regulation of signal transduction	GO:0009968	206	0.148	Mouse
learning	GO:0007612	75	0.147
camera type eye development	GO:0043010	4	0.145
cell division	GO:0051301	248	0.143
cellular protein localization	GO:0034613	160	0.142
regulation of axon guidance	GO:1902667	10	0.142
negative regulation of cell differentiation	GO:0045596	143	0.141
ras protein signal transduction	GO:0007265	88	0.141	Mouse
regulation of anatomical structure size	GO:0090066	163	0.140
ribonucleotide metabolic process	GO:0009259	145	0.140
cell adhesion	GO:0007155	136	0.138
negative regulation of cellular component organization	GO:0051129	108	0.138
ribonucleoside metabolic process	GO:0009119	127	0.134
axon extension involved in axon guidance	GO:0048846	10	0.134
single organismal cell cell adhesion	GO:0016337	45	0.131
nucleoside phosphate metabolic process	GO:0006753	162	0.130
positive regulation of neuron differentiation	GO:0045666	26	0.128	Mouse
synaptic transmission	GO:0007268	288	0.128
purine ribonucleotide metabolic process	GO:0009150	145	0.127
positive regulation of synapse assembly	GO:0051965	29	0.127
axon choice point recognition	GO:0016198	26	0.126
positive regulation of cell projection organization	GO:0031346	29	0.125	Mouse
transcription from rna polymerase ii promoter	GO:0006366	368	0.121
regulation of cell morphogenesis	GO:0022604	163	0.119
ribonucleoside catabolic process	GO:0042454	112	0.119
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.118
purine ribonucleoside metabolic process	GO:0046128	127	0.117
positive regulation of phosphorus metabolic process	GO:0010562	139	0.117
purine containing compound catabolic process	GO:0072523	112	0.116
response to wounding	GO:0009611	94	0.115
purine nucleoside catabolic process	GO:0006152	112	0.112
phosphorylation	GO:0016310	294	0.111
negative regulation of rna biosynthetic process	GO:1902679	240	0.110
retinal ganglion cell axon guidance	GO:0031290	12	0.109
regulation of synapse structure and activity	GO:0050803	128	0.109
cellular macromolecule localization	GO:0070727	220	0.108
purine nucleotide catabolic process	GO:0006195	109	0.108
regulation of catabolic process	GO:0009894	170	0.105	Mouse
nucleoside triphosphate metabolic process	GO:0009141	120	0.104
negative regulation of multicellular organismal process	GO:0051241	142	0.104
axon extension	GO:0048675	32	0.103
negative regulation of notch signaling pathway	GO:0045746	41	0.101
regulation of phosphorus metabolic process	GO:0051174	210	0.101
motor neuron axon guidance	GO:0008045	58	0.100
cellular macromolecular complex assembly	GO:0034622	153	0.100
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.098
spinal cord development	GO:0021510	1	0.095
nucleobase containing compound catabolic process	GO:0034655	165	0.095
associative learning	GO:0008306	65	0.094
developmental growth	GO:0048589	280	0.094
bmp signaling pathway	GO:0030509	27	0.093
regulation of multicellular organismal development	GO:2000026	414	0.090	Mouse
nucleotide metabolic process	GO:0009117	161	0.090
positive regulation of molecular function	GO:0044093	136	0.090
negative regulation of biosynthetic process	GO:0009890	277	0.090
regionalization	GO:0003002	416	0.089
protein transport	GO:0015031	155	0.089
nucleoside catabolic process	GO:0009164	112	0.088
embryonic heart tube development	GO:0035050	22	0.086
respiratory system development	GO:0060541	213	0.086
positive regulation of neurogenesis	GO:0050769	41	0.085	Mouse
regulation of cell motility	GO:2000145	23	0.085
male courtship behavior veined wing extension	GO:0048065	22	0.084
adult behavior	GO:0030534	137	0.083
positive regulation of biosynthetic process	GO:0009891	316	0.083
eye development	GO:0001654	323	0.083
negative regulation of protein metabolic process	GO:0051248	85	0.081
regulation of notch signaling pathway	GO:0008593	100	0.081
regulation of cell development	GO:0060284	215	0.081	Mouse
neuroblast differentiation	GO:0014016	29	0.080
gtp metabolic process	GO:0046039	72	0.080
regulation of cellular component size	GO:0032535	98	0.080
neuroblast proliferation	GO:0007405	74	0.080
protein phosphorylation	GO:0006468	169	0.079
protein localization	GO:0008104	284	0.079
cellular nitrogen compound catabolic process	GO:0044270	165	0.078
regulation of cellular component biogenesis	GO:0044087	201	0.077
olfactory behavior	GO:0042048	97	0.075
single organism cell adhesion	GO:0098602	47	0.075
epithelial cell differentiation	GO:0030855	322	0.074
positive regulation of cellular component organization	GO:0051130	156	0.073	Mouse
regulation of cell cycle	GO:0051726	291	0.072
nucleobase containing small molecule metabolic process	GO:0055086	174	0.072
nucleoside phosphate catabolic process	GO:1901292	110	0.071
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.071
synaptic target recognition	GO:0008039	45	0.070
rho protein signal transduction	GO:0007266	14	0.070
regulation of excitatory postsynaptic membrane potential	GO:0060079	3	0.069
retina development in camera type eye	GO:0060041	4	0.069
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.068
positive regulation of signal transduction	GO:0009967	223	0.068
positive regulation of signaling	GO:0023056	243	0.066
cellular catabolic process	GO:0044248	372	0.066	Mouse
positive regulation of cell communication	GO:0010647	250	0.066
regulation of ras protein signal transduction	GO:0046578	93	0.066	Mouse
nucleoside triphosphate catabolic process	GO:0009143	108	0.063
ribonucleotide catabolic process	GO:0009261	109	0.063
cell proliferation	GO:0008283	299	0.062
regulation of cytoskeleton organization	GO:0051493	89	0.062
regulation of phosphorylation	GO:0042325	147	0.061
regulation of hydrolase activity	GO:0051336	97	0.061
positive regulation of catalytic activity	GO:0043085	118	0.061
single organism behavior	GO:0044708	391	0.061
reactive oxygen species metabolic process	GO:0072593	22	0.061
negative regulation of axon extension	GO:0030517	3	0.061
regulation of intracellular signal transduction	GO:1902531	236	0.060	Mouse
negative regulation of neurogenesis	GO:0050768	53	0.060
positive regulation of cellular biosynthetic process	GO:0031328	316	0.060
regulation of anatomical structure morphogenesis	GO:0022603	242	0.059
positive regulation of phosphate metabolic process	GO:0045937	139	0.059
positive regulation of nucleotide metabolic process	GO:0045981	55	0.058
neuron neuron synaptic transmission	GO:0007270	14	0.058
positive regulation of proteolysis involved in cellular protein catabolic process	GO:1903052	24	0.058	Mouse
nucleotide catabolic process	GO:0009166	109	0.058
regulation of neural precursor cell proliferation	GO:2000177	35	0.057
ribose phosphate metabolic process	GO:0019693	145	0.057
male mating behavior	GO:0060179	70	0.057
stem cell proliferation	GO:0072089	88	0.056
cell fate specification	GO:0001708	71	0.055
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.055
filopodium assembly	GO:0046847	33	0.053
cellular response to reactive oxygen species	GO:0034614	14	0.053
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.053
carbohydrate derivative catabolic process	GO:1901136	118	0.052
positive regulation of intracellular signal transduction	GO:1902533	116	0.052
negative regulation of synapse assembly	GO:0051964	39	0.051
regulation of cell migration	GO:0030334	22	0.051
response to organic substance	GO:0010033	284	0.051
regulation of locomotion	GO:0040012	42	0.051
mitotic nuclear division	GO:0007067	213	0.051
synaptic growth at neuromuscular junction	GO:0051124	119	0.050
nuclear division	GO:0000280	332	0.050
response to alcohol	GO:0097305	95	0.050
negative regulation of cell development	GO:0010721	62	0.050
positive regulation of protein metabolic process	GO:0051247	128	0.050	Mouse
tube morphogenesis	GO:0035239	191	0.049
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	26	0.049
posttranscriptional regulation of gene expression	GO:0010608	145	0.049
negative regulation of phosphorus metabolic process	GO:0010563	45	0.049
homeostatic process	GO:0042592	199	0.048
positive regulation of cellular component biogenesis	GO:0044089	80	0.048
regulation of cellular catabolic process	GO:0031329	157	0.048	Mouse
regulation of catalytic activity	GO:0050790	185	0.048
homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	18	0.048
central nervous system neuron differentiation	GO:0021953	8	0.047
organophosphate metabolic process	GO:0019637	195	0.047
positive regulation of proteolysis	GO:0045862	52	0.047	Mouse
small gtpase mediated signal transduction	GO:0007264	88	0.046	Mouse
regulation of nucleotide catabolic process	GO:0030811	48	0.046
positive regulation of developmental growth	GO:0048639	62	0.046
olfactory bulb axon guidance	GO:0071678	3	0.045
single organism catabolic process	GO:0044712	228	0.045
cellular response to carbohydrate stimulus	GO:0071322	4	0.045
chromatin assembly or disassembly	GO:0006333	52	0.044
regulation of molecular function	GO:0065009	217	0.044
growth	GO:0040007	359	0.044
guanosine containing compound catabolic process	GO:1901069	74	0.043
phagocytosis	GO:0006909	215	0.043
positive regulation of axon extension	GO:0045773	2	0.043
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.043
glycosyl compound catabolic process	GO:1901658	112	0.043
determination of dorsal ventral asymmetry	GO:0048262	3	0.042
negative regulation of response to stimulus	GO:0048585	258	0.042	Mouse
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.042
axonal fasciculation	GO:0007413	12	0.042
neuron migration	GO:0001764	5	0.042
small molecule metabolic process	GO:0044281	305	0.042
regulation of gtp catabolic process	GO:0033124	44	0.041
regulation of mapk cascade	GO:0043408	92	0.041
negative regulation of cellular protein metabolic process	GO:0032269	85	0.041
gtp catabolic process	GO:0006184	72	0.041
positive regulation of gtp catabolic process	GO:0033126	43	0.040
protein dna complex assembly	GO:0065004	63	0.040
regulation of gtpase activity	GO:0043087	44	0.040
morphogenesis of an epithelium	GO:0002009	276	0.040
anterior posterior pattern specification	GO:0009952	136	0.040
organophosphate catabolic process	GO:0046434	112	0.040
regulation of localization	GO:0032879	275	0.040
spermatogenesis	GO:0007283	200	0.040
intracellular protein transport	GO:0006886	104	0.039
roundabout signaling pathway	GO:0035385	4	0.039
membrane organization	GO:0061024	112	0.039
stem cell development	GO:0048864	79	0.039
central nervous system projection neuron axonogenesis	GO:0021952	6	0.039
negative regulation of phosphate metabolic process	GO:0045936	45	0.039
regulation of purine nucleotide catabolic process	GO:0033121	48	0.038
lateral inhibition	GO:0046331	206	0.037
positive regulation of growth	GO:0045927	75	0.037
glycosyl compound metabolic process	GO:1901657	127	0.037
neuron fate commitment	GO:0048663	50	0.037
regulation of synaptic transmission	GO:0050804	69	0.037
morphogenesis of a polarized epithelium	GO:0001738	93	0.036
gene silencing	GO:0016458	138	0.036
regulation of mitotic cell cycle	GO:0007346	190	0.035
actin filament organization	GO:0007015	126	0.035
regulation of proteolysis	GO:0030162	87	0.035	Mouse
outflow tract morphogenesis	GO:0003151	4	0.035
intracellular transport	GO:0046907	228	0.035
developmental cell growth	GO:0048588	52	0.035
regulation of protein phosphorylation	GO:0001932	64	0.034
regulation of phosphate metabolic process	GO:0019220	210	0.034
posttranscriptional gene silencing by rna	GO:0035194	45	0.034
organelle fission	GO:0048285	340	0.034
regulation of protein localization	GO:0032880	76	0.034
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.034
cellular response to peptide hormone stimulus	GO:0071375	28	0.034
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.034
regulation of gene expression epigenetic	GO:0040029	128	0.034
negative regulation of rna metabolic process	GO:0051253	251	0.033
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.033
positive regulation of neuron projection development	GO:0010976	14	0.033	Mouse
open tracheal system development	GO:0007424	204	0.033
tissue migration	GO:0090130	155	0.033
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.033
cytoplasmic transport nurse cell to oocyte	GO:0007303	12	0.033
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.032	Mouse
membrane depolarization	GO:0051899	4	0.032
regulation of nucleotide metabolic process	GO:0006140	62	0.032
regulation of apoptotic process	GO:0042981	130	0.032
positive regulation of hydrolase activity	GO:0051345	78	0.032
cell cycle phase transition	GO:0044770	140	0.031
salivary gland boundary specification	GO:0007432	8	0.031
anatomical structure homeostasis	GO:0060249	97	0.031
appendage morphogenesis	GO:0035107	397	0.031
regulation of cell substrate adhesion	GO:0010810	2	0.031
regulation of cell adhesion	GO:0030155	27	0.031
neuroblast development	GO:0014019	13	0.030
protein modification by small protein conjugation or removal	GO:0070647	106	0.030	Mouse
branching morphogenesis of an epithelial tube	GO:0048754	45	0.030
convergent extension	GO:0060026	2	0.030
formation of anatomical boundary	GO:0048859	37	0.030
morphogenesis of a branching structure	GO:0001763	45	0.030
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.030
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	12	0.030
retina morphogenesis in camera type eye	GO:0060042	2	0.029
male courtship behavior veined wing vibration	GO:0016545	21	0.029
regulation of cellular component movement	GO:0051270	42	0.028
organ formation	GO:0048645	39	0.028
limb development	GO:0060173	1	0.028
organonitrogen compound catabolic process	GO:1901565	128	0.028
purine ribonucleoside catabolic process	GO:0046130	112	0.028
catabolic process	GO:0009056	409	0.028	Mouse
regulation of stem cell proliferation	GO:0072091	40	0.028
protein catabolic process	GO:0030163	101	0.028	Mouse
regulation of purine nucleotide metabolic process	GO:1900542	62	0.027
adult locomotory behavior	GO:0008344	76	0.027
positive regulation of nucleoside metabolic process	GO:0045979	47	0.027
kidney epithelium development	GO:0072073	3	0.026
regulation of axon extension	GO:0030516	8	0.026
regulation of cellular response to oxidative stress	GO:1900407	4	0.026
regulation of nucleoside metabolic process	GO:0009118	50	0.026
organic cyclic compound catabolic process	GO:1901361	168	0.026
actin cytoskeleton organization	GO:0030036	206	0.026
cell projection assembly	GO:0030031	94	0.026
cytoplasmic transport	GO:0016482	130	0.025
multicellular organismal homeostasis	GO:0048871	41	0.025
actin filament bundle organization	GO:0061572	28	0.025
organic substance transport	GO:0071702	257	0.025
negative regulation of gene expression epigenetic	GO:0045814	77	0.025
sex determination	GO:0007530	18	0.025
guanosine containing compound metabolic process	GO:1901068	74	0.025
neuron projection extension	GO:1990138	32	0.025
regulation of protein modification process	GO:0031399	112	0.025	Mouse
epidermis development	GO:0008544	65	0.025
male courtship behavior veined wing generated song production	GO:0045433	20	0.024
positive regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032436	19	0.024
positive regulation of cellular protein metabolic process	GO:0032270	118	0.024	Mouse
response to ethanol	GO:0045471	59	0.024
embryonic organ development	GO:0048568	50	0.024
protein polymerization	GO:0051258	42	0.024
endocytosis	GO:0006897	310	0.024
camera type eye morphogenesis	GO:0048593	2	0.024
cellular protein modification process	GO:0006464	438	0.024	Mouse
apoptotic process	GO:0006915	159	0.023
imaginal disc derived appendage development	GO:0048737	399	0.023
visual learning	GO:0008542	4	0.023
imaginal disc derived wing morphogenesis	GO:0007476	337	0.023
regulation of circadian rhythm	GO:0042752	49	0.023
kidney development	GO:0001822	3	0.023
positive regulation of rna metabolic process	GO:0051254	271	0.023
photoreceptor cell differentiation	GO:0046530	170	0.022
neural retina development	GO:0003407	4	0.022
protein processing	GO:0016485	68	0.022
establishment of nucleus localization	GO:0040023	26	0.022
compound eye development	GO:0048749	307	0.022
kidney morphogenesis	GO:0060993	3	0.022
positive regulation of programmed cell death	GO:0043068	62	0.021
extrinsic apoptotic signaling pathway	GO:0097191	1	0.021
proteolysis	GO:0006508	192	0.021	Mouse
positive regulation of cell development	GO:0010720	61	0.021	Mouse
positive regulation of gtpase activity	GO:0043547	43	0.021
regulation of protein transport	GO:0051223	57	0.021
posttranscriptional gene silencing	GO:0016441	46	0.021
hindbrain development	GO:0030902	2	0.020
regulation of cell division	GO:0051302	72	0.020
heart morphogenesis	GO:0003007	32	0.020
cell death	GO:0008219	279	0.020
regulation of rho gtpase activity	GO:0032319	20	0.020
positive regulation of macromolecule metabolic process	GO:0010604	405	0.020	Mouse
notch signaling pathway	GO:0007219	120	0.020
muscle organ development	GO:0007517	127	0.020
regulation of cell size	GO:0008361	63	0.020
cellular response to hydrogen peroxide	GO:0070301	7	0.020
protein modification by small protein conjugation	GO:0032446	79	0.019	Mouse
regulation of intracellular protein transport	GO:0033157	46	0.019
regulation of epithelial cell proliferation	GO:0050678	4	0.019
organic substance catabolic process	GO:1901575	308	0.019	Mouse
establishment of protein localization	GO:0045184	163	0.019
negative regulation of molecular function	GO:0044092	51	0.019
branching involved in open tracheal system development	GO:0060446	45	0.019
regulation of organelle organization	GO:0033043	196	0.019
establishment of organelle localization	GO:0051656	122	0.019
chemosensory behavior	GO:0007635	106	0.019
regulation of cell cycle process	GO:0010564	181	0.019
regulation of actin cytoskeleton organization	GO:0032956	42	0.018
wing disc morphogenesis	GO:0007472	344	0.018
negative regulation of wnt signaling pathway	GO:0030178	28	0.018
establishment of spindle orientation	GO:0051294	18	0.018
columnar cuboidal epithelial cell development	GO:0002066	249	0.018
macromolecular complex assembly	GO:0065003	256	0.018
dopamine receptor signaling pathway	GO:0007212	4	0.018
cardiovascular system development	GO:0072358	82	0.018
ovarian follicle cell development	GO:0030707	248	0.018
positive regulation of cell cycle process	GO:0090068	28	0.018
microtubule organizing center organization	GO:0031023	168	0.018
tissue homeostasis	GO:0001894	36	0.018
neuromuscular junction development	GO:0007528	149	0.018
eye morphogenesis	GO:0048592	260	0.018
regulation of rac protein signal transduction	GO:0035020	3	0.018
positive regulation of phosphorylation	GO:0042327	87	0.018
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.018
cellular homeostasis	GO:0019725	80	0.017
gonad development	GO:0008406	50	0.017
regulation of transferase activity	GO:0051338	58	0.017
mapk cascade	GO:0000165	107	0.017
urogenital system development	GO:0001655	72	0.017
regulation of programmed cell death	GO:0043067	152	0.017
regulation of developmental growth	GO:0048638	174	0.017
cellular response to organic substance	GO:0071310	132	0.017
anterior posterior axis specification	GO:0009948	109	0.017
peripheral nervous system development	GO:0007422	52	0.017
leg disc development	GO:0035218	92	0.017
negative regulation of phosphorylation	GO:0042326	35	0.017
programmed cell death	GO:0012501	257	0.017
modification dependent protein catabolic process	GO:0019941	78	0.017	Mouse
social behavior	GO:0035176	4	0.017
establishment or maintenance of cell polarity	GO:0007163	167	0.017
transmembrane transport	GO:0055085	139	0.016
epithelial cell development	GO:0002064	274	0.016
sensory organ morphogenesis	GO:0090596	260	0.016
single organism intracellular transport	GO:1902582	207	0.016
long term memory	GO:0007616	62	0.016
negative regulation of neuron differentiation	GO:0045665	16	0.016
cellular response to endogenous stimulus	GO:0071495	80	0.016
regulation of bmp signaling pathway	GO:0030510	23	0.016
regulation of ras gtpase activity	GO:0032318	38	0.016
cellular response to disaccharide stimulus	GO:0071324	2	0.015
centrosome organization	GO:0051297	163	0.015
regulation of protein catabolic process	GO:0042176	55	0.015	Mouse
rac protein signal transduction	GO:0016601	3	0.015
positive regulation of dendrite morphogenesis	GO:0050775	9	0.015
single organism nuclear import	GO:1902593	51	0.015
regulation of behavior	GO:0050795	75	0.015
protein targeting	GO:0006605	64	0.015
central complex development	GO:0048036	9	0.015
protein maturation	GO:0051604	71	0.015
positive regulation of gene expression	GO:0010628	290	0.015
negative regulation of organelle organization	GO:0010639	56	0.015
skin development	GO:0043588	65	0.015
negative regulation of chemotaxis	GO:0050922	1	0.015
positive chemotaxis	GO:0050918	4	0.015
aromatic compound catabolic process	GO:0019439	166	0.015
stem cell maintenance	GO:0019827	67	0.015
formation of organ boundary	GO:0010160	30	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
positive regulation of autophagy	GO:0010508	21	0.015
single organism cellular localization	GO:1902580	180	0.015
nephron morphogenesis	GO:0072028	3	0.015
negative regulation of intracellular signal transduction	GO:1902532	57	0.015	Mouse
protein import into nucleus	GO:0006606	51	0.015
positive regulation of catabolic process	GO:0009896	105	0.014	Mouse
compound eye photoreceptor cell differentiation	GO:0001751	140	0.014
hemocyte differentiation	GO:0042386	38	0.014
circulatory system development	GO:0072359	82	0.014
development of primary sexual characteristics	GO:0045137	50	0.014
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.014
regulation of actin filament based process	GO:0032970	42	0.014
negative regulation of cytoskeleton organization	GO:0051494	30	0.014
wound healing	GO:0042060	75	0.014
appendage development	GO:0048736	401	0.014
positive regulation of cell differentiation	GO:0045597	64	0.014	Mouse
positive regulation of ras protein signal transduction	GO:0046579	43	0.014
muscle structure development	GO:0061061	224	0.014
negative regulation of cell proliferation	GO:0008285	69	0.014
jak stat cascade	GO:0007259	49	0.014
multi multicellular organism process	GO:0044706	123	0.014
central nervous system neuron development	GO:0021954	8	0.014
substrate dependent cell migration	GO:0006929	3	0.013
regulation of rho protein signal transduction	GO:0035023	20	0.013
imaginal disc derived leg morphogenesis	GO:0007480	80	0.013
signal transduction in response to dna damage	GO:0042770	3	0.013
regulation of wnt signaling pathway	GO:0030111	68	0.013
reproductive system development	GO:0061458	74	0.013
establishment of localization in cell	GO:0051649	402	0.013
regulation of meiosis	GO:0040020	3	0.013

Trim9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.171
disease of anatomical entity	DOID:7	0.171
urinary system disease	DOID:18	0.067
central nervous system disease	DOID:331	0.025
eye disease	DOID:5614	0.016
eye and adnexa disease	DOID:1492	0.016
sensory system disease	DOID:0050155	0.016

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