Drosophila melanogaster

120 known processes

Psc (Dmel_CG3886)

Posterior sex combs

(Aliases: l(2)vr14,l(2)Psc,D-Bmi,Dmel\CG3886,PSC,Psc1,l(2)49Ea,Su(z)2-C,dPSC,CG3886,psc,49Ea,vr14)

Psc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of macromolecule biosynthetic processGO:00105582700.538
chromatin silencingGO:0006342760.441
negative regulation of rna biosynthetic processGO:19026792400.397
negative regulation of transcription dna templatedGO:00458922370.363
negative regulation of gene expressionGO:00106293870.345
negative regulation of rna metabolic processGO:00512532510.321
transcription from rna polymerase ii promoterGO:00063663680.262
Human Mouse
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.243
negative regulation of cellular biosynthetic processGO:00313272770.229
imaginal disc derived appendage morphogenesisGO:00351143950.224
gene silencingGO:00164581380.218
negative regulation of nucleic acid templated transcriptionGO:19035072400.199
intracellular signal transductionGO:00355563000.197
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.194
meiotic cell cycleGO:00513211710.188
positive regulation of nitrogen compound metabolic processGO:00511733540.176
regulation of multicellular organismal developmentGO:20000264140.168
Mouse
imaginal disc derived appendage developmentGO:00487373990.167
regulation of gene silencingGO:0060968630.166
deathGO:00162652840.163
Mouse
regulation of chromatin silencingGO:0031935360.163
cellular protein modification processGO:00064644380.162
Human Mouse
positive regulation of macromolecule metabolic processGO:00106044050.157
Human
regulation of mitotic cell cycleGO:00073461900.151
regulation of gene expression epigeneticGO:00400291280.148
regionalizationGO:00030024160.143
Mouse
positive regulation of cellular biosynthetic processGO:00313283160.133
morphogenesis of an epitheliumGO:00020092760.132
organelle fissionGO:00482853400.121
positive regulation of macromolecule biosynthetic processGO:00105572830.120
eye developmentGO:00016543230.116
axonogenesisGO:00074092900.114
regulation of anatomical structure morphogenesisGO:00226032420.105
eye photoreceptor cell developmentGO:0042462810.102
axon developmentGO:00615642970.101
vesicle mediated transportGO:00161923810.096
compound eye morphogenesisGO:00017452490.094
positive regulation of rna biosynthetic processGO:19026802660.091
regulation of cell developmentGO:00602842150.090
macromolecular complex assemblyGO:00650032560.088
morphogenesis of a polarized epitheliumGO:0001738930.080
chromosome organizationGO:00512763600.079
regulation of intracellular signal transductionGO:19025312360.078
post embryonic appendage morphogenesisGO:00351203850.077
mitotic spindle organizationGO:00070522200.076
positive regulation of gene expressionGO:00106282900.075
ribonucleoside metabolic processGO:00091191270.074
nuclear divisionGO:00002803320.073
compound eye photoreceptor cell differentiationGO:00017511400.072
response to other organismGO:00517072930.072
regulation of cell differentiationGO:00455953020.071
Mouse
purine ribonucleoside metabolic processGO:00461281270.071
photoreceptor cell differentiationGO:00465301700.070
peptidyl lysine acetylationGO:0018394390.070
Mouse
regulation of cellular catabolic processGO:00313291570.069
positive regulation of nucleic acid templated transcriptionGO:19035082660.069
embryonic development via the syncytial blastodermGO:00017001480.069
regulation of organ morphogenesisGO:2000027780.069
tissue morphogenesisGO:00487292970.069
small gtpase mediated signal transductionGO:0007264880.069
multi organism behaviorGO:00517051750.067
dendrite morphogenesisGO:00488131990.066
cellular response to dna damage stimulusGO:00069742230.066
positive regulation of nucleobase containing compound metabolic processGO:00459353320.065
negative regulation of nucleobase containing compound metabolic processGO:00459342610.065
exocrine system developmentGO:00352721620.065
positive regulation of transcription dna templatedGO:00458932660.064
negative regulation of cellular metabolic processGO:00313243820.064
compound eye developmentGO:00487493070.064
positive regulation of rna metabolic processGO:00512542710.064
cell divisionGO:00513012480.063
Mouse
embryonic morphogenesisGO:00485982060.062
Mouse
appendage morphogenesisGO:00351073970.062
imaginal disc derived wing vein morphogenesisGO:0008586440.061
spindle organizationGO:00070512530.059
cellular catabolic processGO:00442483720.058
eye morphogenesisGO:00485922600.058
reproductive behaviorGO:00190981220.058
negative regulation of gene expression epigeneticGO:0045814770.057
gland developmentGO:00487321910.057
response to gravityGO:0009629260.057
regulation of phosphate metabolic processGO:00192202100.056
dendrite developmentGO:00163582040.056
camera type eye developmentGO:004301040.056
actin cytoskeleton organizationGO:00300362060.055
lateral inhibitionGO:00463312060.049
taxisGO:00423303040.049
sister chromatid segregationGO:0000819920.048
actin filament based processGO:00300292200.047
phosphorylationGO:00163102940.047
covalent chromatin modificationGO:00165691060.046
Mouse
apoptotic processGO:00069151590.045
Mouse
body morphogenesisGO:001017120.045
protein dna complex assemblyGO:0065004630.045
regulation of transcription from rna polymerase ii promoterGO:00063573780.045
Human Mouse
cell cycle checkpointGO:0000075950.044
regulation of phosphorus metabolic processGO:00511742100.044
regulation of cell morphogenesisGO:00226041630.044
negative regulation of cell cycleGO:00457861160.044
regulation of small gtpase mediated signal transductionGO:0051056930.043
regulation of cellular component biogenesisGO:00440872010.043
embryo development ending in birth or egg hatchingGO:00097921520.043
Mouse
regulation of cell shapeGO:00083601130.043
internal protein amino acid acetylationGO:0006475380.043
Mouse
regulation of tube size open tracheal systemGO:0035151430.043
appendage developmentGO:00487364010.043
chromosome segregationGO:00070591570.042
negative regulation of nitrogen compound metabolic processGO:00511722650.042
protein acylationGO:0043543420.041
Mouse
chromatin organizationGO:00063252070.041
axis specificationGO:00097981670.041
establishment of localization in cellGO:00516494020.040
pigmentationGO:0043473750.040
positive regulation of catabolic processGO:00098961050.040
single organism catabolic processGO:00447122280.039
single organism behaviorGO:00447083910.039
meiotic nuclear divisionGO:00071261510.039
chemotaxisGO:00069352490.039
organic substance transportGO:00717022570.038
purine containing compound metabolic processGO:00725211550.038
negative regulation of cell cycle processGO:00109481090.038
positive regulation of phosphorus metabolic processGO:00105621390.038
mitotic sister chromatid segregationGO:0000070870.037
negative regulation of cell communicationGO:00106482230.037
Mouse
negative regulation of biosynthetic processGO:00098902770.037
molting cycle processGO:0022404290.036
establishment or maintenance of cell polarityGO:00071631670.036
wing disc morphogenesisGO:00074723440.036
chromatin modificationGO:00165681470.036
regulation of programmed cell deathGO:00430671520.036
Mouse
immune system processGO:00023763470.035
Human Zebrafish Mouse
regulation of catabolic processGO:00098941700.034
phagocytosisGO:00069092150.034
negative regulation of cell proliferationGO:0008285690.033
multi organism reproductive behaviorGO:00447051210.033
muscle structure developmentGO:00610612240.033
response to abiotic stimulusGO:00096283410.033
small molecule metabolic processGO:00442813050.033
sensory organ morphogenesisGO:00905962600.033
imaginal disc derived wing morphogenesisGO:00074763370.032
regulation of chromosome organizationGO:0033044640.032
ribonucleoprotein complex assemblyGO:0022618230.032
positive regulation of biosynthetic processGO:00098913160.032
mitotic cell cycle phase transitionGO:00447721380.031
eye photoreceptor cell differentiationGO:00017541450.031
establishment of tissue polarityGO:0007164870.031
respiratory system developmentGO:00605412130.031
establishment of ommatidial planar polarityGO:0042067490.030
programmed cell deathGO:00125012570.029
Mouse
digestive system developmentGO:00551231490.029
tube developmentGO:00352952440.029
Mouse
developmental pigmentationGO:0048066680.029
single organism intracellular transportGO:19025822070.028
positive regulation of intracellular signal transductionGO:19025331160.028
regulation of mapk cascadeGO:0043408920.028
positive regulation of signal transductionGO:00099672230.027
r3 r4 cell differentiationGO:0048056120.027
peptidyl amino acid modificationGO:00181931050.027
Mouse
positive regulation of cellular component biogenesisGO:0044089800.027
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.027
Human Mouse
nucleoside triphosphate catabolic processGO:00091431080.027
photoreceptor cell developmentGO:0042461960.027
negative regulation of mitotic cell cycle phase transitionGO:19019911030.027
positive regulation of cellular protein metabolic processGO:00322701180.027
Human
developmental programmed cell deathGO:00106231380.027
catabolic processGO:00090564090.027
mitotic cell cycle embryonicGO:0045448380.026
protein modification by small protein conjugation or removalGO:00706471060.026
Human Mouse
ras protein signal transductionGO:0007265880.026
multicellular organismal reproductive behaviorGO:00330571100.026
establishment of planar polarityGO:0001736870.026
regulation of cell cycle processGO:00105641810.025
regulation of embryonic developmentGO:0045995680.025
cellular macromolecular complex assemblyGO:00346221530.025
larval developmentGO:00021641040.025
histone modificationGO:00165701060.025
Mouse
multi multicellular organism processGO:00447061230.024
defense responseGO:00069523000.024
cell deathGO:00082192790.024
Mouse
negative regulation of cell cycle phase transitionGO:19019881030.024
heterocycle catabolic processGO:00467001660.024
organonitrogen compound metabolic processGO:19015643180.024
aromatic compound catabolic processGO:00194391660.024
gland morphogenesisGO:00226121450.024
peptidyl lysine modificationGO:0018205570.024
Mouse
positive regulation of phosphate metabolic processGO:00459371390.024
protein acetylationGO:0006473390.024
Mouse
regulation of apoptotic processGO:00429811300.023
Mouse
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.023
protein dna complex subunit organizationGO:0071824860.023
regulation of neurogenesisGO:00507671580.023
mitotic nuclear divisionGO:00070672130.023
positive regulation of mapk cascadeGO:0043410630.023
regulation of tube architecture open tracheal systemGO:0035152680.023
amine metabolic processGO:0009308120.023
biological adhesionGO:00226101380.023
nucleotide catabolic processGO:00091661090.023
regulation of ras protein signal transductionGO:0046578930.023
negative regulation of developmental processGO:00510932010.022
regulation of cellular protein metabolic processGO:00322682430.022
Human
positive regulation of cellular component organizationGO:00511301560.021
histone acetylationGO:0016573380.021
Mouse
protein modification processGO:00362114380.021
Human Mouse
regulation of hydrolase activityGO:0051336970.021
molting cycle chitin based cuticleGO:0007591560.020
cellular component assembly involved in morphogenesisGO:00109271510.020
endocytosisGO:00068973100.020
locomotory behaviorGO:00076261760.020
regulation of proteolysisGO:0030162870.020
humoral immune responseGO:00069591170.019
Mouse
regulation of catalytic activityGO:00507901850.019
Human Mouse
purine ribonucleoside triphosphate metabolic processGO:00092051190.019
purine nucleotide catabolic processGO:00061951090.019
mrna splicing via spliceosomeGO:0000398730.019
tissue deathGO:00162711020.019
muscle organ developmentGO:00075171270.019
leg disc developmentGO:0035218920.019
regulation of localizationGO:00328792750.019
enzyme linked receptor protein signaling pathwayGO:00071671790.019
gene silencing by rnaGO:0031047570.019
regulation of cell cycleGO:00517262910.019
purine nucleoside triphosphate metabolic processGO:00091441190.019
response to mechanical stimulusGO:0009612280.018
regulation of molecular functionGO:00650092170.018
Human Mouse
salivary gland developmentGO:00074311620.018
cell adhesionGO:00071551360.018
axon guidanceGO:00074112330.018
ocellus pigmentationGO:0033060190.018
camera type eye morphogenesisGO:004859320.018
response to lipopolysaccharideGO:003249640.018
gonad developmentGO:0008406500.018
regulation of mitotic cell cycle phase transitionGO:19019901300.018
notch signaling pathwayGO:00072191200.018
ribose phosphate metabolic processGO:00196931450.017
positive regulation of response to stimulusGO:00485843230.017
striated muscle cell differentiationGO:0051146900.017
segmentationGO:00352822070.017
positive regulation of cellular catabolic processGO:0031331950.017
neurological system processGO:00508773580.017
regulation of lipid transportGO:003236830.017
regulation of mitotic sister chromatid separationGO:0010965280.017
sensory perception of mechanical stimulusGO:0050954720.017
negative regulation of organelle organizationGO:0010639560.017
response to external biotic stimulusGO:00432072930.017
eye pigment metabolic processGO:0042441330.017
regulation of ras gtpase activityGO:0032318380.017
negative regulation of signalingGO:00230572190.017
Mouse
positive regulation of signalingGO:00230562430.017
salivary gland cell autophagic cell deathGO:0035071830.017
actin filament organizationGO:00070151260.017
response to biotic stimulusGO:00096072940.017
positive regulation of hydrolase activityGO:0051345780.016
purine ribonucleoside catabolic processGO:00461301120.016
negative regulation of cell deathGO:0060548810.016
Mouse
positive regulation of molecular functionGO:00440931360.016
Human
positive regulation of catalytic activityGO:00430851180.016
Human
cuticle developmentGO:0042335860.016
dorsal ventral pattern formationGO:00099531330.015
skeletal muscle organ developmentGO:0060538480.015
regulation of phosphorylationGO:00423251470.015
purine nucleotide metabolic processGO:00061631460.015
response to oxygen containing compoundGO:19017002000.015
Mouse Rat
cellular amine metabolic processGO:0044106120.015
rna transportGO:0050658460.015
mapk cascadeGO:00001651070.015
chitin based cuticle developmentGO:0040003490.015
carboxylic acid metabolic processGO:0019752920.015
protein ubiquitinationGO:0016567700.015
Human Mouse
negative regulation of cell differentiationGO:00455961430.015
regulation of meiosisGO:004002030.014
organophosphate metabolic processGO:00196371950.014
positive regulation of purine nucleotide metabolic processGO:1900544550.014
hematopoietic or lymphoid organ developmentGO:0048534570.014
Human Zebrafish Mouse
retina development in camera type eyeGO:006004140.014
inter male aggressive behaviorGO:0002121600.014
cell cell signaling involved in cell fate commitmentGO:00451682100.014
response to organic cyclic compoundGO:0014070890.014
Rat
regulation of cell proliferationGO:00421271630.014
Human Mouse
nucleobase containing compound transportGO:0015931560.014
gtp metabolic processGO:0046039720.014
protein phosphorylationGO:00064681690.014
positive regulation of multicellular organismal processGO:00512401430.014
Mouse
cellular nitrogen compound catabolic processGO:00442701650.014
salivary gland morphogenesisGO:00074351450.014
rna localizationGO:00064031150.014
nitrogen compound transportGO:0071705850.014
cytoplasmic transportGO:00164821300.014
transcription elongation from rna polymerase ii promoterGO:0006368180.014
cellular response to organic substanceGO:00713101320.014
Rat
guanosine containing compound catabolic processGO:1901069740.014
regulation of cytoskeleton organizationGO:0051493890.014
proteolysisGO:00065081920.014
response to bacteriumGO:00096171980.014
stem cell differentiationGO:00488631170.014
negative regulation of multicellular organismal processGO:00512411420.013
cellular ketone metabolic processGO:0042180240.013
purine nucleoside metabolic processGO:00422781270.013
regulation of immune system processGO:00026821760.013
Mouse
regulation of nervous system developmentGO:00519602480.013
hematopoietic progenitor cell differentiationGO:000224410.013
signal transduction in response to dna damageGO:004277030.013
positive regulation of gtpase activityGO:0043547430.013
purine ribonucleoside triphosphate catabolic processGO:00092071080.013
negative regulation of mitotic cell cycleGO:00459301090.013
protein complex biogenesisGO:00702712010.013
glycosyl compound metabolic processGO:19016571270.013
neuron projection guidanceGO:00974852410.013
morphogenesis of embryonic epitheliumGO:0016331940.013
positive regulation of cell communicationGO:00106472500.013
regulation of cell deathGO:00109411730.013
Mouse
positive regulation of developmental processGO:00510941430.013
Mouse
eggshell chorion assemblyGO:0007306660.013
establishment of rna localizationGO:0051236470.013
eggshell formationGO:00307031050.012
regulation of chromosome segregationGO:0051983320.012
negative regulation of apoptotic processGO:0043066630.012
Mouse
regulation of membrane potentialGO:0042391350.012
imaginal disc derived leg morphogenesisGO:0007480800.012
ribonucleotide catabolic processGO:00092611090.012
organic substance catabolic processGO:19015753080.012
positive regulation of nucleotide catabolic processGO:0030813460.012
striated muscle cell developmentGO:0055002500.012
cell motilityGO:00488702510.012
Zebrafish
carbohydrate derivative catabolic processGO:19011361180.012
negative regulation of cellular component organizationGO:00511291080.012
oocyte axis specificationGO:00073091080.012
cellular component disassemblyGO:0022411460.012
regulation of cellular protein catabolic processGO:1903362440.012
regulation of response to external stimulusGO:00321011150.012
oxoacid metabolic processGO:00434361030.012
protein complex assemblyGO:00064612000.012
single organism biosynthetic processGO:00447112060.012
cell proliferationGO:00082832990.012
Human Mouse
nucleoside triphosphate metabolic processGO:00091411200.012
secondary metabolite biosynthetic processGO:0044550240.012
open tracheal system developmentGO:00074242040.011
embryonic pattern specificationGO:00098801740.011
nucleoside phosphate catabolic processGO:19012921100.011
positive regulation of gene expression epigeneticGO:0045815160.011
ribonucleoprotein complex subunit organizationGO:0071826280.011
dorsal appendage formationGO:0046843470.011
regulation of tube length open tracheal systemGO:0035159240.011
regulation of nucleoside metabolic processGO:0009118500.011
regulation of cellular ketone metabolic processGO:001056530.011
muscle cell developmentGO:0055001500.011
transcription initiation from rna polymerase ii promoterGO:0006367250.011
regulation of response to stressGO:00801342000.011
digestive tract developmentGO:00485651490.011
dna templated transcription elongationGO:0006354180.011
regulation of protein stabilityGO:0031647430.011
outflow tract morphogenesisGO:000315140.011
negative regulation of chromosome organizationGO:2001251190.011
regulation of protein metabolic processGO:00512462560.011
Human
protein localizationGO:00081042840.011
organic cyclic compound catabolic processGO:19013611680.011
female meiotic divisionGO:0007143700.011
carbohydrate derivative metabolic processGO:19011352170.011
positive regulation of proteolysisGO:0045862520.010
methylationGO:0032259470.010
Mouse
nucleobase containing compound catabolic processGO:00346551650.010
regulation of organelle organizationGO:00330431960.010
dna templated transcriptional preinitiation complex assemblyGO:0070897200.010
protein maturationGO:0051604710.010
oocyte differentiationGO:00099941450.010
dna metabolic processGO:00062592270.010
Mouse
agingGO:00075681430.010
developmental maturationGO:00217001720.010
neuronal stem cell maintenanceGO:009715040.010

Psc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
musculoskeletal system diseaseDOID:1700.023
nervous system diseaseDOID:86300.014
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
organ system cancerDOID:005068600.011