Drosophila melanogaster

196 known processes

tgo (Dmel_CG11987)

tango

(Aliases: Dmel\CG11987,DARNT,dTgo,Arnt,CG11987,Hif1,ARNT,darnt,HIF-1,Tango,HIF1b,bHLHe4,dARNT,arnt,HIF-1beta,prd7,Tgo,TGO)

tgo biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of neurogenesisGO:00507671580.995
tube morphogenesisGO:00352391910.987
tube developmentGO:00352952440.985
neuron projection guidanceGO:00974852410.984
Zebrafish
axon guidanceGO:00074112330.971
Zebrafish
regulation of neuron differentiationGO:00456641030.963
regulation of multicellular organismal developmentGO:20000264140.962
cell motilityGO:00488702510.956
respiratory system developmentGO:00605412130.943
digestive system developmentGO:00551231490.942
tissue morphogenesisGO:00487292970.935
morphogenesis of an epitheliumGO:00020092760.893
cell migrationGO:00164772380.887
taxisGO:00423303040.882
Zebrafish
establishment of localization in cellGO:00516494020.850
retinal ganglion cell axon guidanceGO:0031290120.837
axon developmentGO:00615642970.825
Zebrafish
positive regulation of nucleobase containing compound metabolic processGO:00459353320.801
positive regulation of transcription dna templatedGO:00458932660.760
central nervous system developmentGO:00074172010.754
embryonic morphogenesisGO:00485982060.748
morphogenesis of a branching epitheliumGO:0061138450.697
axonogenesisGO:00074092900.676
Zebrafish
response to biotic stimulusGO:00096072940.669
transcription from rna polymerase ii promoterGO:00063663680.668
regulation of nervous system developmentGO:00519602480.660
branching involved in open tracheal system developmentGO:0060446450.648
regionalizationGO:00030024160.635
localization of cellGO:00516742570.628
chemotaxisGO:00069352490.627
Zebrafish
cellular protein modification processGO:00064644380.607
Mouse
regulation of cell proliferationGO:00421271630.560
Rat
regulation of synapse organizationGO:00508071100.552
branching morphogenesis of an epithelial tubeGO:0048754450.544
positive regulation of macromolecule metabolic processGO:00106044050.542
gliogenesisGO:0042063800.517
response to external biotic stimulusGO:00432072930.507
ameboidal type cell migrationGO:00016671510.483
morphogenesis of a branching structureGO:0001763450.481
imaginal disc derived appendage developmentGO:00487373990.481
muscle structure developmentGO:00610612240.480
regulation of cell developmentGO:00602842150.468
negative regulation of nucleobase containing compound metabolic processGO:00459342610.463
developmental growthGO:00485892800.450
appendage developmentGO:00487364010.428
regulation of cell differentiationGO:00455953020.412
larval developmentGO:00021641040.401
cell recognitionGO:00080371020.390
wnt signaling pathwayGO:0016055980.382
eye morphogenesisGO:00485922600.372
response to other organismGO:00517072930.365
digestive tract developmentGO:00485651490.361
protein modification processGO:00362114380.355
Mouse
head developmentGO:00603221350.349
body morphogenesisGO:001017120.303
Worm
multi multicellular organism processGO:00447061230.300
positive regulation of rna metabolic processGO:00512542710.296
defense response to other organismGO:00985422250.296
negative regulation of rna biosynthetic processGO:19026792400.286
appendage morphogenesisGO:00351073970.283
muscle cell differentiationGO:00426921030.279
multicellular organismal reproductive behaviorGO:00330571100.269
neurological system processGO:00508773580.267
organonitrogen compound metabolic processGO:19015643180.259
vesicle mediated transportGO:00161923810.251
telencephalon developmentGO:002153720.248
kidney epithelium developmentGO:007207330.248
gland developmentGO:00487321910.244
Zebrafish
cellular component assembly involved in morphogenesisGO:00109271510.244
circulatory system developmentGO:0072359820.243
Zebrafish
negative regulation of neurogenesisGO:0050768530.216
epithelial cell migrationGO:00106311480.214
forebrain developmentGO:003090020.203
Zebrafish
cellular response to endogenous stimulusGO:0071495800.192
growthGO:00400073590.188
negative regulation of nervous system developmentGO:0051961920.183
negative regulation of developmental processGO:00510932010.173
defense responseGO:00069523000.169
negative regulation of cell communicationGO:00106482230.167
intracellular transportGO:00469072280.166
glial cell differentiationGO:0010001350.162
axon choice point recognitionGO:0016198260.161
positive regulation of signalingGO:00230562430.158
columnar cuboidal epithelial cell developmentGO:00020662490.156
regulation of epithelial cell proliferationGO:005067840.154
epithelial tube morphogenesisGO:0060562880.148
blastoderm segmentationGO:00073501590.148
epithelial cell differentiationGO:00308553220.147
defense response to fungusGO:0050832480.144
morphogenesis of embryonic epitheliumGO:0016331940.143
response to bacteriumGO:00096171980.142
negative regulation of signal transductionGO:00099682060.141
regulation of synapse structure and activityGO:00508031280.137
axon midline choice point recognitionGO:0016199260.135
columnar cuboidal epithelial cell differentiationGO:00020652560.135
regulation of anatomical structure morphogenesisGO:00226032420.134
embryonic organ developmentGO:0048568500.133
Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.132
positive regulation of response to stimulusGO:00485843230.128
post embryonic appendage morphogenesisGO:00351203850.127
open tracheal system developmentGO:00074242040.125
synapse assemblyGO:00074161430.124
regulation of wnt signaling pathwayGO:0030111680.122
cell cell signaling involved in cell fate commitmentGO:00451682100.120
positive regulation of macromolecule biosynthetic processGO:00105572830.119
gastrulationGO:0007369700.116
negative regulation of cellular metabolic processGO:00313243820.114
negative regulation of cell proliferationGO:0008285690.114
glial cell migrationGO:0008347310.110
tissue migrationGO:00901301550.107
reproductive system developmentGO:0061458740.106
Mouse
negative regulation of response to stimulusGO:00485852580.100
endocytosisGO:00068973100.097
oxoacid metabolic processGO:00434361030.097
positive regulation of cellular biosynthetic processGO:00313283160.094
cell migration involved in gastrulationGO:004207490.092
single organism intracellular transportGO:19025822070.091
organ growthGO:0035265560.091
positive regulation of cell differentiationGO:0045597640.090
positive regulation of nervous system developmentGO:0051962690.090
positive regulation of gene expressionGO:00106282900.089
cellular response to peptideGO:1901653280.089
positive regulation of cell communicationGO:00106472500.085
negative regulation of rna metabolic processGO:00512532510.084
brain developmentGO:00074201200.084
nephron developmentGO:007200630.084
wing disc morphogenesisGO:00074723440.083
digestive tract morphogenesisGO:00485461270.081
regulation of photoreceptor cell axon guidanceGO:200028950.080
regulation of transcription from rna polymerase ii promoterGO:00063573780.077
small molecule metabolic processGO:00442813050.077
cellular response to growth factor stimulusGO:0071363300.077
positive regulation of nucleic acid templated transcriptionGO:19035082660.076
positive regulation of rna biosynthetic processGO:19026802660.076
regulation of protein modification processGO:00313991120.075
Mouse
olfactory bulb axon guidanceGO:007167830.075
organelle localizationGO:00516401480.074
regulation of cell morphogenesisGO:00226041630.072
mushroom body developmentGO:0016319700.070
lateral inhibitionGO:00463312060.070
establishment or maintenance of cell polarityGO:00071631670.070
sex differentiationGO:0007548810.070
neural precursor cell proliferationGO:0061351750.069
regulation of axon extension involved in axon guidanceGO:004884140.068
regulation of cell morphogenesis involved in differentiationGO:0010769610.065
ovarian follicle cell migrationGO:00072971210.064
kidney developmentGO:000182230.063
single organism behaviorGO:00447083910.063
Fly
regulation of axonogenesisGO:0050770320.063
regulation of localizationGO:00328792750.061
intracellular signal transductionGO:00355563000.061
negative regulation of response to external stimulusGO:0032102220.059
positive regulation of nucleoside metabolic processGO:0045979470.058
chemosensory behaviorGO:00076351060.057
heart morphogenesisGO:0003007320.057
Zebrafish
regulation of cell cycleGO:00517262910.057
compound eye photoreceptor developmentGO:0042051780.056
negative regulation of signalingGO:00230572190.056
negative regulation of protein phosphorylationGO:0001933170.054
regulation of tube architecture open tracheal systemGO:0035152680.054
reproductive structure developmentGO:0048608740.052
Mouse
response to woundingGO:0009611940.051
negative regulation of cell differentiationGO:00455961430.051
single organism cell adhesionGO:0098602470.051
Zebrafish
regulation of phosphorus metabolic processGO:00511742100.051
protein localizationGO:00081042840.051
imaginal disc derived wing margin morphogenesisGO:0008587410.050
cellular macromolecule localizationGO:00707272200.050
stem cell developmentGO:0048864790.049
specification of symmetryGO:0009799130.049
anterior posterior pattern specificationGO:00099521360.048
deathGO:00162652840.047
Rat
embryonic pattern specificationGO:00098801740.047
epithelial cell developmentGO:00020642740.047
positive regulation of signal transductionGO:00099672230.047
negative regulation of cell developmentGO:0010721620.046
oocyte differentiationGO:00099941450.046
regulation of cell migrationGO:0030334220.046
regulation of cell cycle processGO:00105641810.046
gonad developmentGO:0008406500.046
axis specificationGO:00097981670.045
dorsal trunk growth open tracheal systemGO:003500170.045
regulation of cellular response to growth factor stimulusGO:0090287130.045
substrate dependent cell migrationGO:000692930.044
axon extension involved in axon guidanceGO:0048846100.044
nuclear transportGO:0051169720.043
regulation of meiosisGO:004002030.043
regulation of chemotaxisGO:0050920120.043
embryonic axis specificationGO:00005781070.042
cellular macromolecular complex assemblyGO:00346221530.042
multi organism reproductive behaviorGO:00447051210.042
stem cell differentiationGO:00488631170.042
cell junction organizationGO:0034330570.041
negative regulation of transcription dna templatedGO:00458922370.041
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.040
lymph gland developmentGO:0048542280.040
regulation of apoptotic processGO:00429811300.040
Rat
regulation of phosphate metabolic processGO:00192202100.039
cellular response to oxygen containing compoundGO:1901701790.039
photoreceptor cell differentiationGO:00465301700.039
neuron recognitionGO:00080381010.038
response to fungusGO:0009620500.038
heart developmentGO:0007507820.038
Zebrafish
regulation of epithelial cell migrationGO:0010632120.036
striated muscle cell differentiationGO:0051146900.036
regulation of hemocyte proliferationGO:0035206370.035
negative regulation of cellular component organizationGO:00511291080.035
branch fusion open tracheal systemGO:0035147170.035
enzyme linked receptor protein signaling pathwayGO:00071671790.035
ribonucleoside triphosphate metabolic processGO:00091991190.034
segmentationGO:00352822070.034
macromolecular complex assemblyGO:00650032560.034
actin cytoskeleton organizationGO:00300362060.034
cell adhesionGO:00071551360.033
Zebrafish
r7 cell differentiationGO:0045466430.033
cellular response to chemical stimulusGO:00708871990.033
cellular response to nitrogen compoundGO:1901699510.032
regulation of cell motilityGO:2000145230.031
mesenchymal cell differentiationGO:004876210.031
carboxylic acid metabolic processGO:0019752920.031
ovipositionGO:0018991190.030
regulation of response to external stimulusGO:00321011150.030
developmental growth involved in morphogenesisGO:0060560650.030
blood circulationGO:0008015260.030
oocyte developmentGO:00485991240.030
regulation of cell divisionGO:0051302720.029
photoreceptor cell axon guidanceGO:0072499230.029
regulation of response to stressGO:00801342000.029
positive regulation of cellular amino acid metabolic processGO:004576400.028
positive regulation of multicellular organismal processGO:00512401430.028
Human
imaginal disc derived wing morphogenesisGO:00074763370.028
regulation of protein metabolic processGO:00512462560.028
Mouse
embryonic hemopoiesisGO:0035162260.027
synapse organizationGO:00508081960.027
motor neuron axon guidanceGO:0008045580.027
negative regulation of nucleic acid templated transcriptionGO:19035072400.027
endosomal transportGO:0016197440.027
long term memoryGO:0007616620.027
negative regulation of nitrogen compound metabolic processGO:00511722650.027
phagocytosisGO:00069092150.026
negative regulation of gene expressionGO:00106293870.026
positive regulation of ribosome biogenesisGO:009007030.026
imaginal disc growthGO:0007446370.026
eye photoreceptor cell developmentGO:0042462810.026
negative regulation of macromolecule biosynthetic processGO:00105582700.026
positive regulation of biosynthetic processGO:00098913160.026
imaginal disc derived wing vein morphogenesisGO:0008586440.025
wound healingGO:0042060750.025
endomembrane system organizationGO:00102561190.025
carbohydrate derivative metabolic processGO:19011352170.024
regulation of behaviorGO:0050795750.024
Fly
membrane organizationGO:00610241120.024
hindgut developmentGO:0061525580.024
actin filament based processGO:00300292200.024
negative regulation of multicellular organismal processGO:00512411420.024
establishment of tissue polarityGO:0007164870.024
positive regulation of nitrogen compound metabolic processGO:00511733540.024
defense response to bacteriumGO:00427421780.023
connective tissue developmentGO:006144830.023
mesoderm developmentGO:0007498780.023
negative regulation of nucleotide catabolic processGO:003081210.023
regulation of embryonic developmentGO:0045995680.023
regulation of cell adhesionGO:0030155270.023
regulation of axon guidanceGO:1902667100.022
negative regulation of epithelial cell migrationGO:001063310.022
histone h3 k9 modificationGO:0061647120.022
regulation of cellular ketone metabolic processGO:001056530.022
development of primary sexual characteristicsGO:0045137500.022
response to organic substanceGO:00100332840.022
regulation of epithelial cell migration open tracheal systemGO:2000274110.021
small gtpase mediated signal transductionGO:0007264880.021
regulation of striated muscle contractionGO:000694220.021
homeostatic processGO:00425921990.021
regulation of immune system processGO:00026821760.021
retina morphogenesis in camera type eyeGO:006004220.021
programmed cell deathGO:00125012570.021
Rat
receptor mediated endocytosisGO:0006898210.021
photoreceptor cell developmentGO:0042461960.021
negative regulation of phosphate metabolic processGO:0045936450.021
phosphorylationGO:00163102940.021
single organism catabolic processGO:00447122280.021
male sex differentiationGO:0046661250.021
negative regulation of protein metabolic processGO:0051248850.020
retina development in camera type eyeGO:006004140.020
diterpenoid biosynthetic processGO:001610210.020
icosanoid biosynthetic processGO:004645610.020
negative regulation of phosphorus metabolic processGO:0010563450.020
regulation of organelle organizationGO:00330431960.020
tripartite regional subdivisionGO:00073511030.019
camera type eye morphogenesisGO:004859320.019
convergent extensionGO:006002620.018
negative regulation of phosphorylationGO:0042326350.018
positive regulation of cellular amine metabolic processGO:003324000.018
adult locomotory behaviorGO:0008344760.018
organelle assemblyGO:00709251980.018
dendrite guidanceGO:0070983210.018
multicellular organismal agingGO:00102591400.018
cellular ketone metabolic processGO:0042180240.018
cellular response to organonitrogen compoundGO:0071417360.018
positive regulation of protein modification processGO:0031401580.017
Mouse
neuromuscular processGO:0050905210.017
rubidium ion transportGO:003582610.017
negative regulation of molecular functionGO:0044092510.017
cellular amino acid metabolic processGO:0006520610.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.017
regulation of catalytic activityGO:00507901850.017
regulation of cellular component movementGO:0051270420.017
positive regulation of axonogenesisGO:005077220.017
positive regulation of cell migrationGO:003033520.017
hemopoiesisGO:0030097460.016
organonitrogen compound catabolic processGO:19015651280.016
urogenital system developmentGO:0001655720.016
negative regulation of biosynthetic processGO:00098902770.016
oocyte morphogenesisGO:004860130.016
regulation of cellular amino acid metabolic processGO:000652100.015
regulation of molecular functionGO:00650092170.015
positive regulation of cellular component organizationGO:00511301560.015
multi organism behaviorGO:00517051750.015
Worm
endoderm formationGO:000170630.015
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidanceGO:200030520.015
single organismal cell cell adhesionGO:0016337450.015
Zebrafish
cellular response to organic substanceGO:00713101320.015
limb morphogenesisGO:003510810.015
regulation of nuclear divisionGO:0051783580.015
establishment of protein localizationGO:00451841630.015
hindbrain developmentGO:003090220.014
dorsal ventral axon guidanceGO:003356320.014
regulation of locomotionGO:0040012420.014
compound eye photoreceptor cell differentiationGO:00017511400.014
regulation of mitotic cell cycleGO:00073461900.014
positive regulation of developmental processGO:00510941430.013
embryo development ending in birth or egg hatchingGO:00097921520.013
Mouse
regulation of synapse assemblyGO:0051963940.013
organelle fissionGO:00482853400.013
camera type eye developmentGO:004301040.013
nephron epithelium developmentGO:007200930.013
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.013
regulation of cellular amine metabolic processGO:003323830.013
purine ribonucleoside catabolic processGO:00461301120.013
protein complex assemblyGO:00064612000.013
negative regulation of protein modification processGO:0031400290.013
nucleotide catabolic processGO:00091661090.013
cellular response to nutrientGO:003167010.013
positive regulation of immune responseGO:0050778630.013
response to hormoneGO:0009725450.012
cell deathGO:00082192790.012
Rat
regulation of mitotic spindle checkpointGO:190350410.012
genital disc morphogenesisGO:0007483160.012
central nervous system projection neuron axonogenesisGO:002195260.012
response to peptideGO:1901652290.012
arp2 3 complex mediated actin nucleationGO:003431430.012
anterior head segmentationGO:003528830.012
negative regulation of epithelial cell proliferationGO:005068040.012
amine metabolic processGO:0009308120.012
cell fate specificationGO:0001708710.012
Worm
negative regulation of gtpase activityGO:003426010.012
mitochondrial membrane organizationGO:000700630.012
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.012
biological adhesionGO:00226101380.012
Zebrafish
regulation of cell proliferation involved in compound eye morphogenesisGO:200049520.012
dorsal ventral pattern formationGO:00099531330.011
meiotic nuclear envelope disassemblyGO:005107820.011
regulation of cellular protein metabolic processGO:00322682430.011
Mouse
positive regulation of immune system processGO:0002684680.011
protein phosphorylationGO:00064681690.011
hindgut morphogenesisGO:0007442580.011
positive regulation of cell motilityGO:200014730.011
cellular response to peptide hormone stimulusGO:0071375280.011
regulation of intracellular signal transductionGO:19025312360.011
regulation of nucleoside metabolic processGO:0009118500.011
dna catabolic process endonucleolyticGO:000073760.011
anterior posterior axis specificationGO:00099481090.011
spinal cord developmentGO:002151010.011
positive regulation of transportGO:0051050920.011
dendrite morphogenesisGO:00488131990.011
epithelial cell migration open tracheal systemGO:0007427320.011
nucleoside triphosphate catabolic processGO:00091431080.011
negative regulation of nucleotide metabolic processGO:004598040.010
establishment of protein localization to organelleGO:0072594620.010
heart processGO:0003015370.010
neuroblast proliferationGO:0007405740.010
regulation of growthGO:00400082330.010
positive regulation of catalytic activityGO:00430851180.010
positive regulation of hydrolase activityGO:0051345780.010

tgo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.036
musculoskeletal system diseaseDOID:1700.018
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
vascular diseaseDOID:17800.010
aortic aneurysmDOID:362700.010
cardiovascular system diseaseDOID:128700.010
aortic diseaseDOID:52000.010
artery diseaseDOID:005082800.010