IMP: Integrative Multi-species Prediction

Drosophila melanogaster

93 known processes

fws (Dmel_CG6549)

four way stop

(Aliases: anon-EST:Posey162,Cog5,Dmel\CG6549,dCOG5,COG5,CG6549,anon-EST:Posey186,Fws)

FLYBASE: FBgn0024689
Entrez: 35054
UniProtKB: Q9VJD3
UniProtKB: M9NCV1

Process Predictions
Disease Predictions

fws biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
meiotic cytokinesis	GO:0033206	33	0.997
meiotic nuclear division	GO:0007126	151	0.990
meiotic cell cycle	GO:0051321	171	0.988
meiotic cell cycle process	GO:1903046	132	0.987
meiosis ii	GO:0007135	23	0.972
meiosis ii cytokinesis	GO:0007111	11	0.970
cytokinetic process	GO:0032506	27	0.837
meiosis i cytokinesis	GO:0007110	12	0.830
cytokinesis	GO:0000910	90	0.703
nuclear division	GO:0000280	332	0.653
spindle stabilization	GO:0043146	14	0.644
organelle fission	GO:0048285	340	0.633
regulation of microtubule depolymerization	GO:0031114	24	0.584
negative regulation of microtubule polymerization or depolymerization	GO:0031111	21	0.541
cell division	GO:0051301	248	0.536
regulation of protein complex disassembly	GO:0043244	29	0.535
cytoskeleton dependent cytokinesis	GO:0061640	81	0.524
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.459
meiotic spindle stabilization	GO:0043147	8	0.456
contractile ring contraction	GO:0036213	12	0.411
regulation of organelle organization	GO:0033043	196	0.406
actomyosin contractile ring contraction	GO:0000916	12	0.361
protein complex disassembly	GO:0043241	36	0.304
regulation of spindle organization	GO:0090224	17	0.165
regulation of microtubule based process	GO:0032886	49	0.162
cellular component disassembly	GO:0022411	46	0.158
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.142
meiosis i	GO:0007127	59	0.139
negative regulation of protein depolymerization	GO:1901880	23	0.130
cellular protein complex disassembly	GO:0043624	35	0.128
macromolecular complex disassembly	GO:0032984	37	0.122
spindle organization	GO:0007051	253	0.119
meiotic spindle organization	GO:0000212	36	0.119
regulation of cytoskeleton organization	GO:0051493	89	0.091
male meiosis cytokinesis	GO:0007112	26	0.087
regulation of cell cycle	GO:0051726	291	0.079
microtubule polymerization or depolymerization	GO:0031109	39	0.070
negative regulation of microtubule depolymerization	GO:0007026	21	0.069
regulation of cell cycle process	GO:0010564	181	0.062
vesicle mediated transport	GO:0016192	381	0.058
regulation of protein depolymerization	GO:1901879	27	0.056
endocytosis	GO:0006897	310	0.049
translation	GO:0006412	69	0.047
small molecule metabolic process	GO:0044281	305	0.047
negative regulation of cytoskeleton organization	GO:0051494	30	0.044
determination of adult lifespan	GO:0008340	137	0.043
negative regulation of cellular component organization	GO:0051129	108	0.043
pigmentation	GO:0043473	75	0.039
single organism behavior	GO:0044708	391	0.039
cellular protein modification process	GO:0006464	438	0.038
developmental pigmentation	GO:0048066	68	0.036
response to abiotic stimulus	GO:0009628	341	0.035
endomembrane system organization	GO:0010256	119	0.035
body morphogenesis	GO:0010171	2	0.034
pigment metabolic process involved in developmental pigmentation	GO:0043324	33	0.029
protein complex assembly	GO:0006461	200	0.028
organic substance catabolic process	GO:1901575	308	0.025
organelle assembly	GO:0070925	198	0.025
embryo development ending in birth or egg hatching	GO:0009792	152	0.023	Worm
cell motility	GO:0048870	251	0.022	Worm
establishment of rna localization	GO:0051236	47	0.021
protein modification process	GO:0036211	438	0.021
cellular catabolic process	GO:0044248	372	0.020
organonitrogen compound metabolic process	GO:1901564	318	0.020
taxis	GO:0042330	304	0.019
organophosphate metabolic process	GO:0019637	195	0.019
male meiosis chromosome segregation	GO:0007060	10	0.019
chromosome segregation	GO:0007059	157	0.019
carbohydrate derivative metabolic process	GO:1901135	217	0.019
macromolecular complex assembly	GO:0065003	256	0.018
cellular nitrogen compound catabolic process	GO:0044270	165	0.017
nucleobase containing compound transport	GO:0015931	56	0.017
heterocycle catabolic process	GO:0046700	166	0.017
chromosome organization	GO:0051276	360	0.017
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.017
posttranscriptional regulation of gene expression	GO:0010608	145	0.016
single organism catabolic process	GO:0044712	228	0.014
plasma membrane organization	GO:0007009	26	0.014
protein modification by small protein conjugation	GO:0032446	79	0.014
nitrogen compound transport	GO:0071705	85	0.014
single organism biosynthetic process	GO:0044711	206	0.014
membrane organization	GO:0061024	112	0.014
male gamete generation	GO:0048232	201	0.014
negative regulation of protein complex disassembly	GO:0043242	23	0.013
golgi vesicle transport	GO:0048193	27	0.013
phagocytosis	GO:0006909	215	0.013
reproductive behavior	GO:0019098	122	0.013
appendage development	GO:0048736	401	0.013
secretion	GO:0046903	109	0.012
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.012
digestive tract development	GO:0048565	149	0.012
mrna metabolic process	GO:0016071	124	0.012
post embryonic appendage morphogenesis	GO:0035120	385	0.012
oxoacid metabolic process	GO:0043436	103	0.012
golgi organization	GO:0007030	66	0.012
protein complex biogenesis	GO:0070271	201	0.012
nucleobase containing compound catabolic process	GO:0034655	165	0.012
carbohydrate metabolic process	GO:0005975	82	0.012
cell migration	GO:0016477	238	0.011	Worm
actin cytoskeleton organization	GO:0030036	206	0.011
protein dephosphorylation	GO:0006470	27	0.011
lipid metabolic process	GO:0006629	121	0.011
carboxylic acid metabolic process	GO:0019752	92	0.010
rna transport	GO:0050658	46	0.010
multi multicellular organism process	GO:0044706	123	0.010
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.010
actin filament based process	GO:0030029	220	0.010

fws disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.017

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