IMP: Integrative Multi-species Prediction

Drosophila melanogaster

136 known processes

Bap55 (Dmel_CG6546)

Brahma associated protein 55kD

(Aliases: Dmel\CG6546,Baf53,BAF53,BAP55,bap55,CG6546)

Entrez: 36956
FLYBASE: FBgn0025716
UniProtKB: Q7K012

Process Predictions
Disease Predictions

Bap55 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
chromatin remodeling	GO:0006338	72	0.959	Human Mouse
nucleosome organization	GO:0034728	59	0.948
negative regulation of mitotic cell cycle	GO:0045930	109	0.909
negative regulation of gene expression	GO:0010629	387	0.855
protein acylation	GO:0043543	42	0.810	Human
histone acetylation	GO:0016573	38	0.803	Human
protein dna complex subunit organization	GO:0071824	86	0.778
mitotic g2 m transition checkpoint	GO:0044818	70	0.730
positive regulation of gene expression	GO:0010628	290	0.690
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.668
mrna splicing via spliceosome	GO:0000398	73	0.643
chromatin organization	GO:0006325	207	0.638	Human Mouse
transcription from rna polymerase ii promoter	GO:0006366	368	0.625
mitotic cell cycle checkpoint	GO:0007093	88	0.571
positive regulation of rna biosynthetic process	GO:1902680	266	0.567
mrna metabolic process	GO:0016071	124	0.552
regulation of cell proliferation	GO:0042127	163	0.537
mrna processing	GO:0006397	104	0.531
regulation of mitotic cell cycle	GO:0007346	190	0.530
mitotic dna integrity checkpoint	GO:0044774	75	0.526
negative regulation of cell cycle process	GO:0010948	109	0.501
negative regulation of cell cycle phase transition	GO:1901988	103	0.466
endocytosis	GO:0006897	310	0.449
regulation of mrna splicing via spliceosome	GO:0048024	64	0.438
rna splicing via transesterification reactions	GO:0000375	73	0.430
rna splicing	GO:0008380	83	0.428
internal peptidyl lysine acetylation	GO:0018393	38	0.420	Human
vesicle mediated transport	GO:0016192	381	0.416
chromosome organization	GO:0051276	360	0.403	Human Mouse
regulation of cell cycle process	GO:0010564	181	0.395
embryo development ending in birth or egg hatching	GO:0009792	152	0.386	Worm
positive regulation of rna metabolic process	GO:0051254	271	0.368
chromatin assembly or disassembly	GO:0006333	52	0.346
regulation of rna splicing	GO:0043484	69	0.345
regulation of cell cycle	GO:0051726	291	0.343
cell cycle checkpoint	GO:0000075	95	0.343
histone exchange	GO:0043486	21	0.331
mitotic dna damage checkpoint	GO:0044773	74	0.322
immune system process	GO:0002376	347	0.311
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.310
peptidyl lysine modification	GO:0018205	57	0.305	Human
chromatin assembly	GO:0031497	48	0.303
peptidyl lysine acetylation	GO:0018394	39	0.298	Human
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.295
negative regulation of cell cycle	GO:0045786	116	0.293
regulation of meiosis	GO:0040020	3	0.263
macromolecular complex assembly	GO:0065003	256	0.262
regulation of gene silencing	GO:0060968	63	0.259
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.250
regulation of mrna processing	GO:0050684	71	0.244
gene silencing	GO:0016458	138	0.224
dna integrity checkpoint	GO:0031570	81	0.223
mitotic g2 dna damage checkpoint	GO:0007095	69	0.218
mitotic cell cycle phase transition	GO:0044772	138	0.210
rna processing	GO:0006396	147	0.210
chromatin modification	GO:0016568	147	0.210	Human Mouse
regulation of cell cycle phase transition	GO:1901987	130	0.207
apoptotic process	GO:0006915	159	0.207
atp dependent chromatin remodeling	GO:0043044	22	0.194	Human
regulation of cell death	GO:0010941	173	0.190
dna packaging	GO:0006323	91	0.189
positive regulation of molecular function	GO:0044093	136	0.189
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.188
negative regulation of cell death	GO:0060548	81	0.184
intracellular transport	GO:0046907	228	0.173
mrna cis splicing via spliceosome	GO:0045292	1	0.172
larval development	GO:0002164	104	0.172	Worm
cellular macromolecular complex assembly	GO:0034622	153	0.170
organelle fission	GO:0048285	340	0.167
dna metabolic process	GO:0006259	227	0.166
cell division	GO:0051301	248	0.165
death	GO:0016265	284	0.162
nuclear division	GO:0000280	332	0.159
muscle structure development	GO:0061061	224	0.159
g2 dna damage checkpoint	GO:0031572	69	0.155
negative regulation of response to stimulus	GO:0048585	258	0.155
body morphogenesis	GO:0010171	2	0.154
transcription initiation from rna polymerase ii promoter	GO:0006367	25	0.152
cell death	GO:0008219	279	0.146
negative regulation of sister chromatid segregation	GO:0033046	13	0.145
posttranscriptional gene silencing by rna	GO:0035194	45	0.143
regulation of proteolysis	GO:0030162	87	0.134
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.132
regulation of mrna metabolic process	GO:1903311	72	0.132
dna damage checkpoint	GO:0000077	78	0.129
posttranscriptional regulation of gene expression	GO:0010608	145	0.126
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.126
dna repair	GO:0006281	54	0.123
establishment of localization in cell	GO:0051649	402	0.122
segmentation	GO:0035282	207	0.116
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.114
regulation of molecular function	GO:0065009	217	0.112
mrna 3 end processing	GO:0031124	28	0.109
reproductive system development	GO:0061458	74	0.108	Worm
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.108
cell proliferation	GO:0008283	299	0.108
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.106
nuclear transport	GO:0051169	72	0.105
protein acetylation	GO:0006473	39	0.103	Human
cellular response to dsrna	GO:0071359	15	0.100
posttranscriptional gene silencing	GO:0016441	46	0.098
mrna catabolic process	GO:0006402	33	0.097
regulation of sister chromatid segregation	GO:0033045	28	0.096
nuclear export	GO:0051168	24	0.095
regulation of chromosome organization	GO:0033044	64	0.094
regulation of organelle organization	GO:0033043	196	0.090
peptidyl amino acid modification	GO:0018193	105	0.089	Human
macromolecule catabolic process	GO:0009057	161	0.089
histone h2a acetylation	GO:0043968	1	0.088	Human
mrna transport	GO:0051028	15	0.087
cytoplasmic transport	GO:0016482	130	0.087
cellular response to dna damage stimulus	GO:0006974	223	0.083
negative regulation of rna metabolic process	GO:0051253	251	0.083
regulation of cell division	GO:0051302	72	0.083
regulation of apoptotic process	GO:0042981	130	0.083
negative regulation of cellular biosynthetic process	GO:0031327	277	0.079
response to oxygen containing compound	GO:1901700	200	0.079
programmed cell death	GO:0012501	257	0.078
dna templated transcription initiation	GO:0006352	25	0.078
dendrite guidance	GO:0070983	21	0.077
rna capping	GO:0036260	1	0.074
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.071
regulation of cell differentiation	GO:0045595	302	0.070
ras protein signal transduction	GO:0007265	88	0.068
multi organism behavior	GO:0051705	175	0.067
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.067
cellular component disassembly	GO:0022411	46	0.066
proteasomal protein catabolic process	GO:0010498	59	0.065
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.064
regulation of cellular amino acid metabolic process	GO:0006521	0	0.063
covalent chromatin modification	GO:0016569	106	0.062	Human
positive regulation of cell communication	GO:0010647	250	0.059
regulation of nucleocytoplasmic transport	GO:0046822	35	0.059
meiotic nuclear division	GO:0007126	151	0.058
cellular amino acid metabolic process	GO:0006520	61	0.058
positive regulation of catalytic activity	GO:0043085	118	0.058
regulation of protein catabolic process	GO:0042176	55	0.057
rna 3 end processing	GO:0031123	45	0.056
negative regulation of organelle organization	GO:0010639	56	0.054
organic substance transport	GO:0071702	257	0.054
protein complex disassembly	GO:0043241	36	0.053
gene silencing by rna	GO:0031047	57	0.053
alternative mrna splicing via spliceosome	GO:0000380	60	0.052
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.051
positive regulation of cellular amine metabolic process	GO:0033240	0	0.051
organic substance catabolic process	GO:1901575	308	0.050
mitotic sister chromatid separation	GO:0051306	30	0.050
organic cyclic compound catabolic process	GO:1901361	168	0.050
positive regulation of phosphate metabolic process	GO:0045937	139	0.049
positive regulation of response to stimulus	GO:0048584	323	0.049
negative regulation of proteasomal protein catabolic process	GO:1901799	16	0.048
cellular ketone metabolic process	GO:0042180	24	0.048
catabolic process	GO:0009056	409	0.048
phagocytosis	GO:0006909	215	0.048
nucleosome positioning	GO:0016584	3	0.047
regulation of proteasomal protein catabolic process	GO:0061136	39	0.047
negative regulation of rna splicing	GO:0033119	5	0.047
single organism intracellular transport	GO:1902582	207	0.046
intracellular signal transduction	GO:0035556	300	0.046
regulation of cellular protein catabolic process	GO:1903362	44	0.046
cellular catabolic process	GO:0044248	372	0.046
nucleocytoplasmic transport	GO:0006913	72	0.045
negative regulation of apoptotic process	GO:0043066	63	0.045
cellular protein complex assembly	GO:0043623	71	0.045
ncrna metabolic process	GO:0034660	43	0.045
regulation of nuclear division	GO:0051783	58	0.045
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.044
negative regulation of catabolic process	GO:0009895	36	0.043
regulation of multicellular organismal development	GO:2000026	414	0.043
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.043
negative regulation of rna biosynthetic process	GO:1902679	240	0.043
mitotic spindle organization	GO:0007052	220	0.042
regionalization	GO:0003002	416	0.042
regulation of cellular catabolic process	GO:0031329	157	0.042
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.042
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.042
regulation of multi organism process	GO:0043900	131	0.041
chromosome segregation	GO:0007059	157	0.041
response to external biotic stimulus	GO:0043207	293	0.041
regulation of hydrolase activity	GO:0051336	97	0.040
internal protein amino acid acetylation	GO:0006475	38	0.040	Human
positive regulation of transcription dna templated	GO:0045893	266	0.039
cellular response to organic cyclic compound	GO:0071407	32	0.039
regulation of endopeptidase activity	GO:0052548	36	0.039
negative regulation of biosynthetic process	GO:0009890	277	0.039
cellular macromolecule catabolic process	GO:0044265	136	0.039
negative regulation of transcription dna templated	GO:0045892	237	0.039
heterocycle catabolic process	GO:0046700	166	0.039
histone modification	GO:0016570	106	0.038	Human
chromosome separation	GO:0051304	42	0.038
positive regulation of cellular biosynthetic process	GO:0031328	316	0.038
establishment of rna localization	GO:0051236	47	0.037
ribonucleoprotein complex subunit organization	GO:0071826	28	0.037
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031145	30	0.037
spindle organization	GO:0007051	253	0.037
ribonucleoprotein complex assembly	GO:0022618	23	0.036
aromatic compound catabolic process	GO:0019439	166	0.035
positive regulation of signaling	GO:0023056	243	0.035
regulation of heterochromatin assembly	GO:0031445	8	0.035
reproductive structure development	GO:0048608	74	0.035	Worm
single organism catabolic process	GO:0044712	228	0.035
negative regulation of signal transduction	GO:0009968	206	0.034
regulation of cellular protein metabolic process	GO:0032268	243	0.034
positive regulation of intracellular signal transduction	GO:1902533	116	0.034
cellular nitrogen compound catabolic process	GO:0044270	165	0.034
cellular protein modification process	GO:0006464	438	0.033	Human
regulation of chromatin modification	GO:1903308	28	0.033
metaphase anaphase transition of cell cycle	GO:0044784	28	0.033
positive regulation of phosphorus metabolic process	GO:0010562	139	0.033
positive regulation of macromolecule metabolic process	GO:0010604	405	0.033
meiotic cell cycle	GO:0051321	171	0.033
regulation of meiotic cell cycle	GO:0051445	9	0.033
regulation of cellular ketone metabolic process	GO:0010565	3	0.032
regulation of gene expression epigenetic	GO:0040029	128	0.032
protein transport	GO:0015031	155	0.032
organic acid metabolic process	GO:0006082	103	0.032
regulation of mitosis	GO:0007088	56	0.032
oviposition	GO:0018991	19	0.032
nucleosome mobilization	GO:0042766	9	0.031
dna templated transcription elongation	GO:0006354	18	0.031
regulation of chromosome segregation	GO:0051983	32	0.030
response to organic substance	GO:0010033	284	0.030
regulation of mitotic sister chromatid separation	GO:0010965	28	0.030
carboxylic acid metabolic process	GO:0019752	92	0.030
gonad development	GO:0008406	50	0.030	Worm
cullin deneddylation	GO:0010388	3	0.029
regulation of microtubule based process	GO:0032886	49	0.029
positive regulation of signal transduction	GO:0009967	223	0.029
nitrogen compound transport	GO:0071705	85	0.028
regulation of cellular amine metabolic process	GO:0033238	3	0.028
modification dependent macromolecule catabolic process	GO:0043632	79	0.027
rna localization	GO:0006403	115	0.027
negative regulation of protein catabolic process	GO:0042177	17	0.027
multicellular organismal reproductive behavior	GO:0033057	110	0.026
positive regulation of phosphorylation	GO:0042327	87	0.026
notch signaling pathway	GO:0007219	120	0.026
regulation of phosphate metabolic process	GO:0019220	210	0.026
negative regulation of cellular catabolic process	GO:0031330	34	0.026
genitalia development	GO:0048806	26	0.025	Worm
protein processing	GO:0016485	68	0.025
hemopoiesis	GO:0030097	46	0.025
regulation of intracellular transport	GO:0032386	64	0.025
regulation of protein metabolic process	GO:0051246	256	0.025
protein modification process	GO:0036211	438	0.025	Human
protein complex assembly	GO:0006461	200	0.024
negative regulation of cell differentiation	GO:0045596	143	0.024
amine metabolic process	GO:0009308	12	0.024
homeostatic process	GO:0042592	199	0.024
negative regulation of proteolysis	GO:0045861	31	0.024
imaginal disc derived wing morphogenesis	GO:0007476	337	0.024
regulation of intracellular signal transduction	GO:1902531	236	0.023
dna conformation change	GO:0071103	105	0.023
ribonucleoprotein complex biogenesis	GO:0022613	31	0.023
protein deneddylation	GO:0000338	8	0.023
response to abiotic stimulus	GO:0009628	341	0.023
positive regulation of cell proliferation	GO:0008284	47	0.022
dna templated transcriptional preinitiation complex assembly	GO:0070897	20	0.022
oxoacid metabolic process	GO:0043436	103	0.022
embryonic morphogenesis	GO:0048598	206	0.022
developmental growth	GO:0048589	280	0.022
blastoderm segmentation	GO:0007350	159	0.021
regulation of catalytic activity	GO:0050790	185	0.021
proteolysis	GO:0006508	192	0.021
organonitrogen compound metabolic process	GO:1901564	318	0.021
regulation of mitotic metaphase anaphase transition	GO:0030071	26	0.020
spliceosomal complex assembly	GO:0000245	1	0.020
negative regulation of protein processing	GO:0010955	31	0.020
mitotic nuclear division	GO:0007067	213	0.020
negative regulation of proteolysis involved in cellular protein catabolic process	GO:1903051	17	0.020
negative regulation of meiotic cell cycle	GO:0051447	2	0.020
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.019
regulation of protein processing	GO:0070613	32	0.019
stem cell maintenance	GO:0019827	67	0.019
stem cell proliferation	GO:0072089	88	0.019
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.019
negative regulation of developmental process	GO:0051093	201	0.019
nucleobase containing compound transport	GO:0015931	56	0.019
multi multicellular organism process	GO:0044706	123	0.019
regulation of cellular localization	GO:0060341	136	0.019
regulation of protein modification process	GO:0031399	112	0.019
cell cycle phase transition	GO:0044770	140	0.019
nucleobase containing compound catabolic process	GO:0034655	165	0.019
myofibril assembly	GO:0030239	36	0.018
lymph gland development	GO:0048542	28	0.018
rna interference	GO:0016246	27	0.018
mitotic sister chromatid segregation	GO:0000070	87	0.018
eye development	GO:0001654	323	0.018	Human
growth	GO:0040007	359	0.018
cellular response to organic substance	GO:0071310	132	0.018
regulation of phosphorus metabolic process	GO:0051174	210	0.018
negative regulation of chromosome organization	GO:2001251	19	0.017
cellular amine metabolic process	GO:0044106	12	0.017
digestive system development	GO:0055123	149	0.017
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.017
cytoplasmic mrna processing body assembly	GO:0033962	10	0.017
regulation of response to stress	GO:0080134	200	0.017
establishment of organelle localization	GO:0051656	122	0.017
pronuclear migration	GO:0035046	4	0.017
negative regulation of cell communication	GO:0010648	223	0.017
gene silencing by mirna	GO:0035195	22	0.016
appendage development	GO:0048736	401	0.016
negative regulation of signaling	GO:0023057	219	0.016
negative regulation of chromosome segregation	GO:0051985	14	0.016
positive regulation of cell cycle	GO:0045787	43	0.016
regulation of dna templated transcription elongation	GO:0032784	17	0.016
translation	GO:0006412	69	0.016
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	16	0.016
negative regulation of molecular function	GO:0044092	51	0.016
establishment of protein localization	GO:0045184	163	0.016
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.016
positive regulation of intracellular transport	GO:0032388	42	0.016
anatomical structure homeostasis	GO:0060249	97	0.016
positive regulation of hydrolase activity	GO:0051345	78	0.016
rna transport	GO:0050658	46	0.016
sister chromatid segregation	GO:0000819	92	0.016
nucleotide excision repair	GO:0006289	8	0.015
spinal cord development	GO:0021510	1	0.015	Rat
response to temperature stimulus	GO:0009266	106	0.015
regulation of catabolic process	GO:0009894	170	0.015
regulation of programmed cell death	GO:0043067	152	0.015
heterochromatin assembly	GO:0031507	13	0.015
nucleosome assembly	GO:0006334	35	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.015
negative regulation of mitotic sister chromatid separation	GO:2000816	13	0.015
negative regulation of gene expression epigenetic	GO:0045814	77	0.015
carbohydrate derivative metabolic process	GO:1901135	217	0.014
regulation of protein complex disassembly	GO:0043244	29	0.014
organelle assembly	GO:0070925	198	0.014
stem cell differentiation	GO:0048863	117	0.014
negative regulation of cellular component organization	GO:0051129	108	0.014
protein neddylation	GO:0045116	5	0.014
protein targeting to nucleus	GO:0044744	51	0.014
unsaturated fatty acid biosynthetic process	GO:0006636	1	0.014
carbohydrate metabolic process	GO:0005975	82	0.013
organophosphate catabolic process	GO:0046434	112	0.013
response to dsrna	GO:0043331	15	0.013
regulation of phosphorylation	GO:0042325	147	0.013
post embryonic appendage morphogenesis	GO:0035120	385	0.013
molting cycle	GO:0042303	56	0.013
positive regulation of heterochromatin assembly	GO:0031453	5	0.013
antimicrobial humoral response	GO:0019730	99	0.013
regulation of smoothened signaling pathway	GO:0008589	28	0.013
sensory organ morphogenesis	GO:0090596	260	0.013
sister chromatid cohesion	GO:0007062	18	0.013
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.013
regulation of transport	GO:0051049	181	0.013
receptor mediated endocytosis	GO:0006898	21	0.013
regulation of response to dna damage stimulus	GO:2001020	23	0.013
hematopoietic or lymphoid organ development	GO:0048534	57	0.012
positive regulation of cellular protein metabolic process	GO:0032270	118	0.012
regulation of developmental growth	GO:0048638	174	0.012
positive regulation of chromatin silencing	GO:0031937	16	0.012
response to other organism	GO:0051707	293	0.012
endomembrane system organization	GO:0010256	119	0.012
regulation of protein maturation	GO:1903317	32	0.012
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.012
small gtpase mediated signal transduction	GO:0007264	88	0.012
negative regulation of cell division	GO:0051782	17	0.012
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	15	0.012
primary mirna processing	GO:0031053	5	0.012
regulation of peptidase activity	GO:0052547	39	0.012
rna catabolic process	GO:0006401	37	0.012
protein maturation	GO:0051604	71	0.012
positive regulation of multicellular organismal process	GO:0051240	143	0.011
regulation of erbb signaling pathway	GO:1901184	42	0.011
rna export from nucleus	GO:0006405	12	0.011
peptidyl lysine trimethylation	GO:0018023	6	0.011
positive regulation of proteolysis	GO:0045862	52	0.011
formation of a compartment boundary	GO:0060288	4	0.011
negative regulation of programmed cell death	GO:0043069	72	0.011
phospholipid transport	GO:0015914	2	0.011
cellular protein localization	GO:0034613	160	0.011
cellular response to ketone	GO:1901655	17	0.011
digestive tract morphogenesis	GO:0048546	127	0.011
negative regulation of protein maturation	GO:1903318	31	0.011
modification dependent protein catabolic process	GO:0019941	78	0.011
regulation of mapk cascade	GO:0043408	92	0.011
multi organism reproductive behavior	GO:0044705	121	0.011
mapk cascade	GO:0000165	107	0.011
sarcomere organization	GO:0045214	26	0.011
mitochondrial membrane organization	GO:0007006	3	0.010
compound eye morphogenesis	GO:0001745	249	0.010
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.010
positive regulation of mapk cascade	GO:0043410	63	0.010
protein complex biogenesis	GO:0070271	201	0.010
regulation of chromatin assembly	GO:0010847	9	0.010
intracellular receptor signaling pathway	GO:0030522	19	0.010
protein dna complex assembly	GO:0065004	63	0.010
regulation of dna metabolic process	GO:0051052	34	0.010

Bap55 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.053

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