IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

bbc (Dmel_CG6016)

bb in a boxcar

(Aliases: Dmel\CG6016,CG6016)

Entrez: 36496
FLYBASE: FBgn0033844
UniProtKB: A1Z9E0
UniProtKB: A1Z9D9

Process Predictions
Disease Predictions

bbc biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
phosphatidylethanolamine metabolic process	GO:0046337	1	0.608
organophosphate metabolic process	GO:0019637	195	0.113	Mouse
protein complex assembly	GO:0006461	200	0.102
cellular lipid metabolic process	GO:0044255	83	0.095	Mouse
protein modification process	GO:0036211	438	0.089
protein complex biogenesis	GO:0070271	201	0.083
phosphatidic acid metabolic process	GO:0046473	1	0.083
vesicle mediated transport	GO:0016192	381	0.074	Fly
response to abiotic stimulus	GO:0009628	341	0.073
purine nucleotide metabolic process	GO:0006163	146	0.073
macromolecular complex assembly	GO:0065003	256	0.063
regionalization	GO:0003002	416	0.062
lipid metabolic process	GO:0006629	121	0.058	Mouse
centrosome duplication	GO:0051298	121	0.056
small molecule metabolic process	GO:0044281	305	0.056	Mouse
endocytosis	GO:0006897	310	0.053	Fly
carbohydrate derivative biosynthetic process	GO:1901137	85	0.052
phosphorylation	GO:0016310	294	0.048
catabolic process	GO:0009056	409	0.047
cellular response to organic substance	GO:0071310	132	0.047
very long chain fatty acid metabolic process	GO:0000038	4	0.046
response to biotic stimulus	GO:0009607	294	0.046
centrosome organization	GO:0051297	163	0.046
membrane fusion	GO:0061025	42	0.045
cellular macromolecular complex assembly	GO:0034622	153	0.045
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.042
nucleotide metabolic process	GO:0009117	161	0.038
regulation of phosphorus metabolic process	GO:0051174	210	0.037
purine ribonucleoside catabolic process	GO:0046130	112	0.037
organonitrogen compound metabolic process	GO:1901564	318	0.036	Mouse
alditol phosphate metabolic process	GO:0052646	2	0.036
microtubule organizing center organization	GO:0031023	168	0.035
regulation of heart contraction	GO:0008016	21	0.034
oxoacid metabolic process	GO:0043436	103	0.034
regulation of developmental growth	GO:0048638	174	0.034
phagocytosis	GO:0006909	215	0.034	Fly
carboxylic acid metabolic process	GO:0019752	92	0.033
positive regulation of cell communication	GO:0010647	250	0.033
cellular protein modification process	GO:0006464	438	0.033
response to external biotic stimulus	GO:0043207	293	0.032
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.031
transcription from rna polymerase ii promoter	GO:0006366	368	0.031
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.030
intracellular signal transduction	GO:0035556	300	0.030
organelle assembly	GO:0070925	198	0.030
body morphogenesis	GO:0010171	2	0.030
response to bacterium	GO:0009617	198	0.030
regulation of defense response	GO:0031347	102	0.029
centrosome cycle	GO:0007098	137	0.029
organophosphate catabolic process	GO:0046434	112	0.029
homeostatic process	GO:0042592	199	0.029
response to nitrogen compound	GO:1901698	90	0.029
wing disc morphogenesis	GO:0007472	344	0.029
embryonic axis specification	GO:0000578	107	0.028
response to oxygen containing compound	GO:1901700	200	0.028
cell death	GO:0008219	279	0.028
lipid biosynthetic process	GO:0008610	46	0.028	Mouse
regulation of system process	GO:0044057	36	0.028
defense response to other organism	GO:0098542	225	0.028
carbohydrate derivative metabolic process	GO:1901135	217	0.027
eye photoreceptor cell differentiation	GO:0001754	145	0.027
regulation of intracellular signal transduction	GO:1902531	236	0.027
molting cycle chitin based cuticle	GO:0007591	56	0.027
response to nutrient levels	GO:0031667	114	0.027
positive regulation of multicellular organismal process	GO:0051240	143	0.027
nucleotide catabolic process	GO:0009166	109	0.027
purine containing compound catabolic process	GO:0072523	112	0.026
defense response to gram negative bacterium	GO:0050829	94	0.026
nucleoside triphosphate metabolic process	GO:0009141	120	0.026
glycerolipid metabolic process	GO:0046486	34	0.026	Mouse
positive regulation of molecular function	GO:0044093	136	0.025
nucleoside phosphate metabolic process	GO:0006753	162	0.025
ribose phosphate metabolic process	GO:0019693	145	0.025
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.025
tube morphogenesis	GO:0035239	191	0.025
response to other organism	GO:0051707	293	0.025
organic acid metabolic process	GO:0006082	103	0.025
axon development	GO:0061564	297	0.025
regulation of phosphate metabolic process	GO:0019220	210	0.024
cellular response to chemical stimulus	GO:0070887	199	0.024
positive regulation of phosphorus metabolic process	GO:0010562	139	0.024
mating	GO:0007618	120	0.024
modification dependent protein catabolic process	GO:0019941	78	0.024
nucleoside catabolic process	GO:0009164	112	0.024
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.022
nucleoside phosphate catabolic process	GO:1901292	110	0.022
positive regulation of phosphate metabolic process	GO:0045937	139	0.022
lateral inhibition	GO:0046331	206	0.022
negative regulation of response to stimulus	GO:0048585	258	0.022
aromatic compound catabolic process	GO:0019439	166	0.022
detection of stimulus	GO:0051606	156	0.022
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.022
protein acylation	GO:0043543	42	0.022
positive regulation of response to stimulus	GO:0048584	323	0.021
molting cycle	GO:0042303	56	0.021
purine containing compound metabolic process	GO:0072521	155	0.021
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.021
immune response	GO:0006955	246	0.021
ribonucleotide catabolic process	GO:0009261	109	0.021
nucleobase containing small molecule metabolic process	GO:0055086	174	0.021
ribonucleoside catabolic process	GO:0042454	112	0.021
segmentation	GO:0035282	207	0.021
purine ribonucleotide metabolic process	GO:0009150	145	0.020
heterocycle catabolic process	GO:0046700	166	0.020
purine ribonucleotide catabolic process	GO:0009154	109	0.020
embryonic development via the syncytial blastoderm	GO:0001700	148	0.020
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.020
single organism catabolic process	GO:0044712	228	0.019
response to organic substance	GO:0010033	284	0.019
response to starvation	GO:0042594	97	0.019
positive regulation of rna biosynthetic process	GO:1902680	266	0.019
regulation of growth	GO:0040008	233	0.019
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.018
embryo development ending in birth or egg hatching	GO:0009792	152	0.018	Worm
positive regulation of macromolecule metabolic process	GO:0010604	405	0.018
single organism membrane fusion	GO:0044801	42	0.018
heart contraction	GO:0060047	26	0.018
positive regulation of catalytic activity	GO:0043085	118	0.018
response to organonitrogen compound	GO:0010243	75	0.018
glycosyl compound metabolic process	GO:1901657	127	0.018
purine nucleoside metabolic process	GO:0042278	127	0.017
detection of stimulus involved in sensory perception	GO:0050906	92	0.017
positive regulation of cellular biosynthetic process	GO:0031328	316	0.017
cellular catabolic process	GO:0044248	372	0.017
single organism cellular localization	GO:1902580	180	0.017
multicellular organismal homeostasis	GO:0048871	41	0.017
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.017
long chain fatty acid metabolic process	GO:0001676	3	0.017
glycoprotein metabolic process	GO:0009100	41	0.017
defense response to bacterium	GO:0042742	178	0.017
carbohydrate derivative catabolic process	GO:1901136	118	0.017
ribonucleoside metabolic process	GO:0009119	127	0.016
ribonucleotide metabolic process	GO:0009259	145	0.016
cellular macromolecule catabolic process	GO:0044265	136	0.016
response to temperature stimulus	GO:0009266	106	0.016
protein dna complex assembly	GO:0065004	63	0.016
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.016
ubiquitin dependent protein catabolic process	GO:0006511	78	0.016
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.016
heart process	GO:0003015	37	0.016
regulation of localization	GO:0032879	275	0.015
cellular amine metabolic process	GO:0044106	12	0.015	Mouse
protein localization	GO:0008104	284	0.015
defense response	GO:0006952	300	0.015
photoreceptor cell differentiation	GO:0046530	170	0.015
regulation of cellular catabolic process	GO:0031329	157	0.015
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.015
anterior posterior axis specification	GO:0009948	109	0.014
response to endogenous stimulus	GO:0009719	119	0.014
regulation of response to stress	GO:0080134	200	0.014
regulation of phosphorylation	GO:0042325	147	0.014
protein catabolic process	GO:0030163	101	0.014
regulation of anatomical structure size	GO:0090066	163	0.014
organelle fusion	GO:0048284	46	0.014
glycoprotein biosynthetic process	GO:0009101	41	0.014
negative regulation of cellular metabolic process	GO:0031324	382	0.014
response to extracellular stimulus	GO:0009991	116	0.014
tripartite regional subdivision	GO:0007351	103	0.014
regulation of transport	GO:0051049	181	0.014
protein phosphorylation	GO:0006468	169	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.014
nucleobase containing compound catabolic process	GO:0034655	165	0.014
purine nucleoside catabolic process	GO:0006152	112	0.014
multicellular organismal reproductive behavior	GO:0033057	110	0.014
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.014
notch signaling pathway	GO:0007219	120	0.013
organophosphate biosynthetic process	GO:0090407	46	0.013	Mouse
organic substance catabolic process	GO:1901575	308	0.013
cellular response to oxygen containing compound	GO:1901701	79	0.013
reproductive structure development	GO:0048608	74	0.013
cellular nitrogen compound catabolic process	GO:0044270	165	0.013
regulation of immune response	GO:0050776	118	0.013
positive regulation of cellular catabolic process	GO:0031331	95	0.013
organonitrogen compound biosynthetic process	GO:1901566	117	0.013	Mouse
positive regulation of cellular component organization	GO:0051130	156	0.013
growth	GO:0040007	359	0.013
endomembrane system organization	GO:0010256	119	0.013
reproductive system development	GO:0061458	74	0.013
single organism biosynthetic process	GO:0044711	206	0.013	Mouse
positive regulation of signal transduction	GO:0009967	223	0.013
camera type eye development	GO:0043010	4	0.013
axis specification	GO:0009798	167	0.013
response to heat	GO:0009408	63	0.012
cell aging	GO:0007569	2	0.012
cellular response to endogenous stimulus	GO:0071495	80	0.012
glycosyl compound catabolic process	GO:1901658	112	0.012
regulation of catalytic activity	GO:0050790	185	0.012
membrane organization	GO:0061024	112	0.012
positive regulation of cell motility	GO:2000147	3	0.012
regulation of molecular function	GO:0065009	217	0.012
organonitrogen compound catabolic process	GO:1901565	128	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.012
negative regulation of growth	GO:0045926	84	0.012
embryonic pattern specification	GO:0009880	174	0.012
locomotory behavior	GO:0007626	176	0.012
regulation of catabolic process	GO:0009894	170	0.012
nucleoside monophosphate catabolic process	GO:0009125	39	0.012
blastoderm segmentation	GO:0007350	159	0.011
nucleoside triphosphate catabolic process	GO:0009143	108	0.011
cellular modified amino acid metabolic process	GO:0006575	45	0.011
ion transport	GO:0006811	145	0.011
response to oxidative stress	GO:0006979	86	0.011
multi organism behavior	GO:0051705	175	0.011
positive regulation of immune response	GO:0050778	63	0.011
cellular protein complex assembly	GO:0043623	71	0.011
cellular response to hormone stimulus	GO:0032870	44	0.011
negative regulation of signal transduction	GO:0009968	206	0.011
anterior posterior pattern specification	GO:0009952	136	0.011
monocarboxylic acid metabolic process	GO:0032787	29	0.011
positive regulation of cell differentiation	GO:0045597	64	0.011
single organism carbohydrate metabolic process	GO:0044723	72	0.011
establishment or maintenance of cell polarity	GO:0007163	167	0.011
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.011
regulation of multi organism process	GO:0043900	131	0.011
developmental growth	GO:0048589	280	0.010
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.010
actin cytoskeleton organization	GO:0030036	206	0.010
oocyte development	GO:0048599	124	0.010
positive regulation of developmental process	GO:0051094	143	0.010
head development	GO:0060322	135	0.010
cellular protein catabolic process	GO:0044257	83	0.010
organic cyclic compound catabolic process	GO:1901361	168	0.010
purine nucleotide catabolic process	GO:0006195	109	0.010
chromatin organization	GO:0006325	207	0.010
dorsal ventral pattern formation	GO:0009953	133	0.010
compound eye development	GO:0048749	307	0.010
multicellular organism growth	GO:0035264	46	0.010
o glycan processing	GO:0016266	3	0.010

bbc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.039
cardiovascular system disease	DOID:1287	0.018
nervous system disease	DOID:863	0.014
central nervous system disease	DOID:331	0.013
musculoskeletal system disease	DOID:17	0.011
myopathy	DOID:423	0.011
muscle tissue disease	DOID:66	0.011
muscular disease	DOID:0080000	0.011

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