Drosophila melanogaster

143 known processes

pic (Dmel_CG7769)

piccolo

(Aliases: Ddb1,D-DDB1,1258/16,263/16,l(3)87Dh,Dmel\CG7769,1366/03,153636_at,dDdb1,l(3)S136603,0263/16,d-ddb1,DDB1,DDB-1,CG7769)

pic biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
g2 dna damage checkpointGO:0031572690.984
dna metabolic processGO:00062592270.946
mitotic dna integrity checkpointGO:0044774750.936
positive regulation of nitrogen compound metabolic processGO:00511733540.934
mitotic dna damage checkpointGO:0044773740.904
mitotic g2 m transition checkpointGO:0044818700.880
regulation of cell cycle processGO:00105641810.874
dna integrity checkpointGO:0031570810.872
regulation of cell cycle phase transitionGO:19019871300.847
positive regulation of gene expressionGO:00106282900.828
positive regulation of rna metabolic processGO:00512542710.819
mitotic g2 dna damage checkpointGO:0007095690.807
positive regulation of nucleic acid templated transcriptionGO:19035082660.782
cell cycle phase transitionGO:00447701400.782
dna damage checkpointGO:0000077780.707
nucleobase containing compound catabolic processGO:00346551650.653
eggshell chorion gene amplificationGO:000730790.645
mitotic cell cycle checkpointGO:0007093880.607
negative regulation of gene expressionGO:00106293870.590
positive regulation of nucleobase containing compound metabolic processGO:00459353320.564
positive regulation of macromolecule metabolic processGO:00106044050.553
nuclear transportGO:0051169720.539
aromatic compound catabolic processGO:00194391660.508
regulation of gene expression epigeneticGO:00400291280.487
reproductive structure developmentGO:0048608740.452
dna replicationGO:0006260480.440
regulation of cell cycleGO:00517262910.412
regulation of mitotic cell cycle phase transitionGO:19019901300.395
positive regulation of transcription dna templatedGO:00458932660.387
cellular catabolic processGO:00442483720.382
regulation of transcription from rna polymerase ii promoterGO:00063573780.382
mitotic cell cycle phase transitionGO:00447721380.368
response to abiotic stimulusGO:00096283410.367
negative regulation of cell cycle processGO:00109481090.362
mrna metabolic processGO:00160711240.359
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.357
small molecule metabolic processGO:00442813050.336
defense responseGO:00069523000.334
intracellular transportGO:00469072280.308
heterocycle catabolic processGO:00467001660.306
positive regulation of macromolecule biosynthetic processGO:00105572830.303
organic cyclic compound catabolic processGO:19013611680.302
immune system processGO:00023763470.282
deathGO:00162652840.280
cellular macromolecule catabolic processGO:00442651360.280
establishment of localization in cellGO:00516494020.278
chromatin organizationGO:00063252070.276
single organism biosynthetic processGO:00447112060.270
rna catabolic processGO:0006401370.264
negative regulation of mitotic cell cycle phase transitionGO:19019911030.262
protein targeting to nucleusGO:0044744510.255
programmed cell deathGO:00125012570.244
positive regulation of cellular biosynthetic processGO:00313283160.243
single organism intracellular transportGO:19025822070.241
developmental programmed cell deathGO:00106231380.241
negative regulation of cell cycle phase transitionGO:19019881030.226
cellular nitrogen compound catabolic processGO:00442701650.223
chromosome organizationGO:00512763600.202
catabolic processGO:00090564090.199
negative regulation of mitotic cell cycleGO:00459301090.189
positive regulation of biosynthetic processGO:00098913160.189
dna endoreduplicationGO:0042023220.187
cell cycle dna replicationGO:0044786230.186
response to external biotic stimulusGO:00432072930.186
regulation of cell cycle g1 s phase transitionGO:1902806230.185
regulation of cellular catabolic processGO:00313291570.185
smad protein import into nucleusGO:0007184110.184
dna biosynthetic processGO:0071897240.183
protein complex assemblyGO:00064612000.169
negative regulation of macromolecule biosynthetic processGO:00105582700.168
negative regulation of cellular metabolic processGO:00313243820.164
development of primary sexual characteristicsGO:0045137500.164
organic substance catabolic processGO:19015753080.159
response to radiationGO:00093141550.155
cell deathGO:00082192790.154
negative regulation of cell cycleGO:00457861160.149
organophosphate metabolic processGO:00196371950.145
transcription from rna polymerase ii promoterGO:00063663680.145
positive regulation of cell proliferationGO:0008284470.144
hemopoiesisGO:0030097460.142
regulation of mitotic cell cycleGO:00073461900.141
nucleotide metabolic processGO:00091171610.141
immune responseGO:00069552460.141
regulation of multicellular organismal developmentGO:20000264140.141
regulation of programmed cell deathGO:00430671520.139
cell proliferationGO:00082832990.129
nucleocytoplasmic transportGO:0006913720.127
nucleotide excision repairGO:000628980.122
mrna catabolic processGO:0006402330.120
organic acid metabolic processGO:00060821030.118
nucleobase containing small molecule metabolic processGO:00550861740.117
cell cycle checkpointGO:0000075950.116
regulation of cell proliferationGO:00421271630.114
histone acetylationGO:0016573380.112
negative regulation of neuron deathGO:1901215180.109
multi organism behaviorGO:00517051750.109
negative regulation of nucleic acid templated transcriptionGO:19035072400.107
regulation of developmental growthGO:00486381740.107
regulation of growthGO:00400082330.106
organonitrogen compound metabolic processGO:19015643180.105
mitotic nuclear divisionGO:00070672130.104
cellular response to extracellular stimulusGO:0031668640.103
negative regulation of cell differentiationGO:00455961430.102
negative regulation of apoptotic processGO:0043066630.102
body morphogenesisGO:001017120.099
anatomical structure homeostasisGO:0060249970.097
protein import into nucleusGO:0006606510.096
positive regulation of rna biosynthetic processGO:19026802660.095
negative regulation of rna biosynthetic processGO:19026792400.091
negative regulation of transcription dna templatedGO:00458922370.090
chromatin modificationGO:00165681470.089
nucleoside triphosphate metabolic processGO:00091411200.089
regulation of cellular response to stressGO:0080135890.088
positive regulation of growthGO:0045927750.087
protein modification processGO:00362114380.087
embryo development ending in birth or egg hatchingGO:00097921520.086
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.085
negative regulation of biosynthetic processGO:00098902770.085
single organism catabolic processGO:00447122280.082
chromatin remodelingGO:0006338720.081
ribonucleoside catabolic processGO:00424541120.080
negative regulation of rna metabolic processGO:00512532510.079
histone modificationGO:00165701060.078
single organism nuclear importGO:1902593510.074
cellular response to dna damage stimulusGO:00069742230.073
atp metabolic processGO:0046034490.072
organic substance transportGO:00717022570.071
regulation of dna metabolic processGO:0051052340.068
regulation of g1 s transition of mitotic cell cycleGO:2000045230.068
regulation of apoptotic processGO:00429811300.068
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.066
immune system developmentGO:0002520570.066
protein transportGO:00150311550.066
negative regulation of nucleobase containing compound metabolic processGO:00459342610.066
regulation of protein metabolic processGO:00512462560.064
posttranscriptional gene silencing by rnaGO:0035194450.064
cellular macromolecule localizationGO:00707272200.062
negative regulation of multicellular organismal processGO:00512411420.061
dna amplificationGO:0006277110.059
sex differentiationGO:0007548810.059
nuclear exportGO:0051168240.059
regulation of cell differentiationGO:00455953020.057
ribonucleotide metabolic processGO:00092591450.052
oxidation reduction processGO:00551141230.052
cytoplasmic transportGO:00164821300.051
protein localization to nucleusGO:0034504550.051
intracellular protein transportGO:00068861040.051
purine nucleoside metabolic processGO:00422781270.051
purine nucleotide metabolic processGO:00061631460.051
nitrogen compound transportGO:0071705850.051
nuclear divisionGO:00002803320.050
cellular response to abiotic stimulusGO:0071214580.050
gene silencing by rnaGO:0031047570.049
purine nucleoside triphosphate metabolic processGO:00091441190.049
ribose phosphate metabolic processGO:00196931450.048
nuclear importGO:0051170510.048
response to endogenous stimulusGO:00097191190.048
purine ribonucleoside triphosphate metabolic processGO:00092051190.047
positive regulation of cellular catabolic processGO:0031331950.047
generation of precursor metabolites and energyGO:0006091420.046
reproductive system developmentGO:0061458740.045
positive regulation of response to stimulusGO:00485843230.045
positive regulation of cellular amine metabolic processGO:003324000.045
posttranscriptional gene silencingGO:0016441460.044
gene silencingGO:00164581380.044
intracellular signal transductionGO:00355563000.044
nucleotide catabolic processGO:00091661090.043
single organism cellular localizationGO:19025801800.043
spindle organizationGO:00070512530.043
regulation of cell deathGO:00109411730.043
larval developmentGO:00021641040.042
negative regulation of cellular biosynthetic processGO:00313272770.041
eye developmentGO:00016543230.040
genitalia developmentGO:0048806260.040
carbohydrate derivative metabolic processGO:19011352170.039
macromolecular complex assemblyGO:00650032560.038
purine ribonucleoside triphosphate catabolic processGO:00092071080.037
immune effector processGO:0002252980.037
regulation of intracellular transportGO:0032386640.037
regulation of execution phase of apoptosisGO:190011750.036
compound eye developmentGO:00487493070.036
purine ribonucleoside metabolic processGO:00461281270.036
cell cycle g1 s phase transitionGO:0044843310.033
heart developmentGO:0007507820.033
regulation of protein export from nucleusGO:004682530.033
g1 s transition of mitotic cell cycleGO:0000082310.033
neurological system processGO:00508773580.033
insulin like growth factor receptor signaling pathwayGO:004800950.033
negative regulation of programmed cell deathGO:0043069720.033
response to extracellular stimulusGO:00099911160.033
organonitrogen compound catabolic processGO:19015651280.033
purine ribonucleotide metabolic processGO:00091501450.032
protein localizationGO:00081042840.031
nucleoside phosphate metabolic processGO:00067531620.031
ribonucleoside metabolic processGO:00091191270.031
purine containing compound catabolic processGO:00725231120.030
protein importGO:0017038550.030
gonad developmentGO:0008406500.030
internal peptidyl lysine acetylationGO:0018393380.030
growthGO:00400073590.030
regulation of nuclear divisionGO:0051783580.030
homeostatic processGO:00425921990.029
oxoacid metabolic processGO:00434361030.029
response to woundingGO:0009611940.029
ribonucleoside triphosphate metabolic processGO:00091991190.029
regulation of hydrolase activityGO:0051336970.028
macromolecule catabolic processGO:00090571610.028
nucleoside phosphate catabolic processGO:19012921100.028
ribonucleoside triphosphate catabolic processGO:00092031080.028
rna processingGO:00063961470.027
protein targetingGO:0006605640.027
ribonucleotide catabolic processGO:00092611090.027
response to other organismGO:00517072930.027
regulation of mrna metabolic processGO:1903311720.026
positive regulation of multicellular organismal processGO:00512401430.026
hematopoietic or lymphoid organ developmentGO:0048534570.026
negative regulation of immune system processGO:0002683500.026
compound eye photoreceptor developmentGO:0042051780.026
oocyte microtubule cytoskeleton polarizationGO:0008103220.026
positive regulation of catalytic activityGO:00430851180.025
defense response to other organismGO:00985422250.025
cellular ketone metabolic processGO:0042180240.025
regionalizationGO:00030024160.025
signal transduction in response to dna damageGO:004277030.024
response to uvGO:0009411240.024
organelle fissionGO:00482853400.024
tissue deathGO:00162711020.024
purine containing compound metabolic processGO:00725211550.024
hematopoietic progenitor cell differentiationGO:000224410.024
negative regulation of lamellocyte differentiationGO:003520450.024
salivary gland cell autophagic cell deathGO:0035071830.024
glycosyl compound catabolic processGO:19016581120.024
agingGO:00075681430.023
meiotic cell cycleGO:00513211710.023
response to organic cyclic compoundGO:0014070890.023
stem cell differentiationGO:00488631170.023
intrinsic apoptotic signaling pathwayGO:0097193160.023
covalent chromatin modificationGO:00165691060.023
cellular response to external stimulusGO:0071496660.022
regulation of intracellular signal transductionGO:19025312360.022
response to biotic stimulusGO:00096072940.022
purine nucleotide catabolic processGO:00061951090.022
purine nucleoside triphosphate catabolic processGO:00091461080.022
oocyte microtubule cytoskeleton organizationGO:0016325350.022
cellular ion homeostasisGO:0006873390.022
meiotic nuclear divisionGO:00071261510.022
regulation of translationGO:0006417560.022
histolysisGO:00075591020.022
compound eye morphogenesisGO:00017452490.021
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.021
innate immune responseGO:00450871440.021
regulation of immune system processGO:00026821760.021
response to organic substanceGO:00100332840.021
post embryonic hemopoiesisGO:0035166170.021
carboxylic acid metabolic processGO:0019752920.020
rna localizationGO:00064031150.020
mitochondrion organizationGO:0007005650.020
positive regulation of hydrolase activityGO:0051345780.020
digestive system developmentGO:00551231490.020
nucleoside catabolic processGO:00091641120.019
regulation of phosphorus metabolic processGO:00511742100.019
protein localization to organelleGO:0033365820.019
gliogenesisGO:0042063800.019
cellular response to chemical stimulusGO:00708871990.018
establishment of protein localization to organelleGO:0072594620.018
regulation of organelle organizationGO:00330431960.018
apoptotic signaling pathwayGO:0097190270.018
central nervous system developmentGO:00074172010.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
eye photoreceptor cell differentiationGO:00017541450.017
defense response to gram negative bacteriumGO:0050829940.017
regulation of response to stressGO:00801342000.017
rna interferenceGO:0016246270.017
regulation of cell divisionGO:0051302720.017
ribonucleoside monophosphate metabolic processGO:0009161510.017
endocytosisGO:00068973100.017
carbohydrate derivative catabolic processGO:19011361180.017
positive regulation of phosphate metabolic processGO:00459371390.017
regulation of mitosisGO:0007088560.017
lipid storageGO:0019915380.017
positive regulation of signal transductionGO:00099672230.016
organonitrogen compound biosynthetic processGO:19015661170.016
nucleoside triphosphate catabolic processGO:00091431080.016
cell recognitionGO:00080371020.016
neuron apoptotic processGO:0051402170.016
multicellular organismal reproductive behaviorGO:00330571100.016
oocyte developmentGO:00485991240.016
ribonucleoprotein complex biogenesisGO:0022613310.016
enzyme linked receptor protein signaling pathwayGO:00071671790.016
lipid biosynthetic processGO:0008610460.016
positive regulation of signalingGO:00230562430.016
protein complex biogenesisGO:00702712010.016
positive regulation of catabolic processGO:00098961050.016
regulation of cytoplasmic transportGO:1903649470.015
salivary gland histolysisGO:0035070880.015
multi multicellular organism processGO:00447061230.015
establishment of protein localizationGO:00451841630.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
positive regulation of developmental processGO:00510941430.015
regulation of nucleocytoplasmic transportGO:0046822350.015
nucleoside metabolic processGO:00091161270.014
dendrite morphogenesisGO:00488131990.014
regulation of mrna processingGO:0050684710.014
energy derivation by oxidation of organic compoundsGO:0015980320.014
exocrine system developmentGO:00352721620.014
positive regulation of cellular protein metabolic processGO:00322701180.013
autophagic cell deathGO:0048102830.013
regulation of mrna splicing via spliceosomeGO:0048024640.013
positive regulation of mitotic cell cycle phase transitionGO:1901992200.013
cellular homeostasisGO:0019725800.013
proteolysisGO:00065081920.013
glycosyl compound metabolic processGO:19016571270.013
purine nucleoside monophosphate metabolic processGO:0009126500.013
regulation of nucleotide catabolic processGO:0030811480.013
positive regulation of nucleotide metabolic processGO:0045981550.013
cell divisionGO:00513012480.012
positive regulation of cell communicationGO:00106472500.012
positive regulation of intracellular signal transductionGO:19025331160.012
cellular macromolecular complex assemblyGO:00346221530.012
wing disc pattern formationGO:0035222660.012
regulation of alternative mrna splicing via spliceosomeGO:0000381600.012
negative regulation of cell deathGO:0060548810.012
cellular chemical homeostasisGO:0055082400.012
lipid metabolic processGO:00066291210.012
regulation of catalytic activityGO:00507901850.012
posttranscriptional regulation of gene expressionGO:00106081450.012
positive regulation of cell cycle processGO:0090068280.012
response to light stimulusGO:00094161240.012
induction of programmed cell death by ecdysoneGO:0035078120.012
regulation of protein localizationGO:0032880760.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
protein dna complex subunit organizationGO:0071824860.011
compound eye photoreceptor cell differentiationGO:00017511400.011
nuclear dna replicationGO:003326010.011
wound healingGO:0042060750.011
phagocytosisGO:00069092150.011
nuclear transcribed mrna catabolic processGO:0000956240.011
mrna transportGO:0051028150.011
centrosome cycleGO:00070981370.011
regulation of catabolic processGO:00098941700.011
response to decreased oxygen levelsGO:0036293580.010
regulation of response to dna damage stimulusGO:2001020230.010
organophosphate catabolic processGO:00464341120.010
positive regulation of mitotic cell cycleGO:0045931340.010

pic disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.025
musculoskeletal system cancerDOID:006010000.025
cancerDOID:16200.025
connective tissue cancerDOID:20100.025
organ system cancerDOID:005068600.025