Drosophila melanogaster

117 known processes

spn-A (Dmel_CG7948)

spindle A

(Aliases: Dm Rad51,Dmrad51,CG7948,RA51,DMR1,Dmel\CG7948,RA51_DROME,dmRAD51,rad51,DMR,RAD51,D37788,Spn-A,Rad51,spnA,DmRad51,DMR/DroRAD51,Rad51dm,DmRAD51)

spn-A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
reciprocal meiotic recombinationGO:0007131191.000
Yeast
meiotic nuclear divisionGO:00071261510.999
dna recombinationGO:0006310320.991
reciprocal dna recombinationGO:0035825190.990
Yeast
meiotic cell cycle processGO:19030461320.986
Yeast Worm
organelle fissionGO:00482853400.965
dna metabolic processGO:00062592270.959
female meiotic divisionGO:0007143700.955
chorion containing eggshell formationGO:00073041050.948
meiotic cell cycleGO:00513211710.948
meiosis iGO:0007127590.946
Yeast
double strand break repairGO:0006302260.938
germarium derived oocyte fate determinationGO:0007294260.921
transcription from rna polymerase ii promoterGO:00063663680.913
germarium derived egg chamber formationGO:00072931010.908
nuclear divisionGO:00002803320.901
double strand break repair via nonhomologous end joiningGO:000630350.895
chromosome segregationGO:00070591570.886
Worm
columnar cuboidal epithelial cell differentiationGO:00020652560.873
karyosome formationGO:0030717220.811
nucleotide excision repairGO:000628980.799
oocyte differentiationGO:00099941450.791
meiotic chromosome segregationGO:0045132590.762
Worm
nucleobase containing compound catabolic processGO:00346551650.709
Human Yeast Worm
negative regulation of cellular biosynthetic processGO:00313272770.682
non recombinational repairGO:000072670.651
double strand break repair via homologous recombinationGO:0000724130.632
oocyte developmentGO:00485991240.617
columnar cuboidal epithelial cell developmentGO:00020662490.612
chromosome organizationGO:00512763600.495
negative regulation of rna metabolic processGO:00512532510.492
recombinational repairGO:0000725130.473
cellular nitrogen compound catabolic processGO:00442701650.432
Human Yeast Worm
mitotic dna damage checkpointGO:0044773740.429
embryo development ending in birth or egg hatchingGO:00097921520.419
Worm
ovarian follicle cell developmentGO:00307072480.407
regulation of phosphorylationGO:00423251470.399
oocyte anterior posterior axis specificationGO:0007314720.382
negative regulation of biosynthetic processGO:00098902770.366
aromatic compound catabolic processGO:00194391660.361
Human Yeast Worm
response to uvGO:0009411240.360
dna synthesis involved in dna repairGO:000073150.359
anterior posterior axis specificationGO:00099481090.353
organelle fusionGO:0048284460.343
oocyte fate determinationGO:0030716270.332
negative regulation of rna biosynthetic processGO:19026792400.307
regulation of transcription from rna polymerase ii promoterGO:00063573780.291
axis specificationGO:00097981670.291
negative regulation of nucleic acid templated transcriptionGO:19035072400.280
negative regulation of macromolecule biosynthetic processGO:00105582700.278
embryonic pattern specificationGO:00098801740.274
negative regulation of nitrogen compound metabolic processGO:00511722650.272
negative regulation of cellular metabolic processGO:00313243820.269
rna localizationGO:00064031150.266
cellular response to dna damage stimulusGO:00069742230.264
germarium derived oocyte differentiationGO:0030706290.260
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.256
macromolecule catabolic processGO:00090571610.254
dna geometric changeGO:0032392160.241
Human
organic substance catabolic processGO:19015753080.229
Human Yeast Worm
developmental maturationGO:00217001720.226
response to ionizing radiationGO:0010212320.225
Human
polarity specification of dorsal ventral axisGO:000995160.222
segmentationGO:00352822070.218
oocyte axis specificationGO:00073091080.218
protein modification processGO:00362114380.216
chromatin organizationGO:00063252070.213
anterior posterior pattern specificationGO:00099521360.211
phosphorylationGO:00163102940.209
cell deathGO:00082192790.206
Worm
response to organonitrogen compoundGO:0010243750.199
intracellular mrna localizationGO:0008298660.197
dna double strand break processingGO:000072930.195
cellular macromolecule localizationGO:00707272200.181
negative regulation of gene expressionGO:00106293870.180
purine ribonucleoside metabolic processGO:00461281270.176
Human Yeast Worm
specification of axis polarityGO:006500160.170
glycosyl compound catabolic processGO:19016581120.167
Human Yeast Worm
regionalizationGO:00030024160.164
positive regulation of intracellular signal transductionGO:19025331160.162
epithelial cell differentiationGO:00308553220.159
double strand break repair via synthesis dependent strand annealingGO:004500360.156
eggshell chorion assemblyGO:0007306660.155
negative regulation of transcription dna templatedGO:00458922370.154
cell divisionGO:00513012480.153
regulation of cell cycle processGO:00105641810.153
organic cyclic compound catabolic processGO:19013611680.153
Human Yeast Worm
positive regulation of gene expressionGO:00106282900.149
eggshell formationGO:00307031050.149
positive regulation of cell communicationGO:00106472500.148
carbohydrate derivative catabolic processGO:19011361180.148
Human Yeast Worm
dna replicationGO:0006260480.148
Human
oocyte dorsal ventral axis specificationGO:0007310340.146
embryonic axis specificationGO:00005781070.145
pole plasm rna localizationGO:0007316520.144
cell cycle checkpointGO:0000075950.141
purine ribonucleoside triphosphate catabolic processGO:00092071080.141
Human Yeast Worm
cellular protein modification processGO:00064644380.136
regulation of cell cycleGO:00517262910.136
oocyte constructionGO:00073081120.135
response to light stimulusGO:00094161240.134
mrna metabolic processGO:00160711240.130
regulation of mrna splicing via spliceosomeGO:0048024640.129
tripartite regional subdivisionGO:00073511030.127
negative regulation of cell cycleGO:00457861160.125
cellular catabolic processGO:00442483720.125
Human Yeast Worm
dna repairGO:0006281540.123
regulation of mitotic cell cycleGO:00073461900.120
regulation of cellular response to stressGO:0080135890.114
purine containing compound metabolic processGO:00725211550.113
Human Yeast Worm
regulation of cell cycle phase transitionGO:19019871300.111
regulation of phosphate metabolic processGO:00192202100.110
cellular component assembly involved in morphogenesisGO:00109271510.104
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.102
pole plasm assemblyGO:0007315610.099
positive regulation of response to stimulusGO:00485843230.098
agingGO:00075681430.097
regulation of intracellular signal transductionGO:19025312360.097
growthGO:00400073590.096
apoptotic signaling pathwayGO:0097190270.095
Worm
catabolic processGO:00090564090.095
Human Yeast Worm
single organism membrane organizationGO:0044802930.093
single organism cellular localizationGO:19025801800.092
regulation of developmental growthGO:00486381740.091
positive regulation of signalingGO:00230562430.089
organophosphate metabolic processGO:00196371950.088
Human Yeast Worm
mitotic dna integrity checkpointGO:0044774750.086
regulation of mapk cascadeGO:0043408920.086
alternative mrna splicing via spliceosomeGO:0000380600.082
negative regulation of developmental processGO:00510932010.082
ribose phosphate metabolic processGO:00196931450.081
Human Yeast Worm
reproductive system developmentGO:0061458740.079
development of primary sexual characteristicsGO:0045137500.079
positive regulation of programmed cell deathGO:0043068620.079
pole plasm oskar mrna localizationGO:0045451460.078
regulation of cell proliferationGO:00421271630.077
regulation of catalytic activityGO:00507901850.076
body morphogenesisGO:001017120.075
regulation of cellular protein metabolic processGO:00322682430.075
intracellular signal transductionGO:00355563000.075
Worm
regulation of organelle organizationGO:00330431960.075
purine ribonucleoside monophosphate metabolic processGO:0009167500.075
Human Yeast Worm
regulation of protein metabolic processGO:00512462560.074
dna damage checkpointGO:0000077780.074
pole plasm mrna localizationGO:0019094490.073
regulation of phosphorus metabolic processGO:00511742100.073
ribonucleoside catabolic processGO:00424541120.071
Human Yeast Worm
purine ribonucleotide metabolic processGO:00091501450.071
Human Yeast Worm
g2 m transition of mitotic cell cycleGO:0000086190.070
cellular macromolecule catabolic processGO:00442651360.068
translesion synthesisGO:001998520.068
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.065
multicellular organismal agingGO:00102591400.064
negative regulation of nucleobase containing compound metabolic processGO:00459342610.063
purine nucleoside metabolic processGO:00422781270.062
Human Yeast Worm
female meiosis chromosome segregationGO:0016321330.062
regulation of mrna metabolic processGO:1903311720.061
response to abiotic stimulusGO:00096283410.059
Human
epithelial cell developmentGO:00020642740.059
deathGO:00162652840.059
Worm
nucleoside catabolic processGO:00091641120.059
Human Yeast Worm
positive regulation of cellular protein metabolic processGO:00322701180.058
response to radiationGO:00093141550.057
Human
immune system developmentGO:0002520570.056
dorsal appendage formationGO:0046843470.055
mrna processingGO:00063971040.054
anterior posterior axis specification embryoGO:00085951030.054
dna conformation changeGO:00711031050.054
Human Worm
positive regulation of macromolecule biosynthetic processGO:00105572830.053
positive regulation of cellular component organizationGO:00511301560.052
purine ribonucleoside catabolic processGO:00461301120.051
Human Yeast Worm
gene silencingGO:00164581380.049
vesicle mediated transportGO:00161923810.049
positive regulation of phosphorylationGO:0042327870.048
regulation of response to stressGO:00801342000.047
gene silencing by rnaGO:0031047570.047
maternal determination of anterior posterior axis embryoGO:0008358740.047
regulation of nervous system developmentGO:00519602480.046
blastoderm segmentationGO:00073501590.046
establishment or maintenance of cell polarityGO:00071631670.045
larval developmentGO:00021641040.044
nucleotide metabolic processGO:00091171610.043
Human Yeast Worm
protein phosphorylationGO:00064681690.043
negative regulation of protein metabolic processGO:0051248850.042
purine nucleoside catabolic processGO:00061521120.042
Human Yeast Worm
positive regulation of macromolecule metabolic processGO:00106044050.041
Human
positive regulation of signal transductionGO:00099672230.041
eggshell chorion gene amplificationGO:000730790.041
sex differentiationGO:0007548810.041
mitotic cell cycle phase transitionGO:00447721380.041
male gamete generationGO:00482322010.040
single organism behaviorGO:00447083910.040
response to nitrogen compoundGO:1901698900.040
establishment of localization in cellGO:00516494020.039
purine nucleoside triphosphate catabolic processGO:00091461080.038
Human Yeast Worm
telomere maintenance via recombinationGO:000072210.038
Yeast
regulation of gene expression epigeneticGO:00400291280.038
positive regulation of phosphorus metabolic processGO:00105621390.038
cellular protein localizationGO:00346131600.038
ribonucleoside triphosphate metabolic processGO:00091991190.038
Human Yeast Worm
positive regulation of cellular biosynthetic processGO:00313283160.037
ribonucleoside triphosphate catabolic processGO:00092031080.037
Human Yeast Worm
negative regulation of cellular component organizationGO:00511291080.037
regulation of meiosisGO:004002030.037
rna processingGO:00063961470.036
meiotic chromosome separationGO:005130780.036
oocyte microtubule cytoskeleton organizationGO:0016325350.036
cognitionGO:00508901410.035
apoptotic processGO:00069151590.035
Worm
dna biosynthetic processGO:0071897240.035
regulation of cell cycle g1 s phase transitionGO:1902806230.034
chromatin modificationGO:00165681470.033
positive regulation of phosphate metabolic processGO:00459371390.033
nuclear dna replicationGO:003326010.033
regulation of meiotic cell cycleGO:005144590.032
telomere maintenanceGO:0000723210.032
Yeast
spindle assembly involved in female meiosisGO:0007056140.031
negative regulation of mitotic cell cycleGO:00459301090.031
positive regulation of cellular catabolic processGO:0031331950.031
ribonucleotide metabolic processGO:00092591450.031
Human Yeast Worm
endocytosisGO:00068973100.031
purine nucleotide catabolic processGO:00061951090.030
Human Yeast Worm
heterocycle catabolic processGO:00467001660.030
Human Yeast Worm
positive regulation of protein metabolic processGO:00512471280.030
polarity specification of anterior posterior axisGO:000994950.030
purine nucleotide metabolic processGO:00061631460.030
Human Yeast Worm
negative regulation of cell communicationGO:00106482230.030
protein complex biogenesisGO:00702712010.030
Human
nucleotide catabolic processGO:00091661090.030
Human Yeast Worm
small molecule metabolic processGO:00442813050.030
Human Yeast Worm
dna integrity checkpointGO:0031570810.029
regulation of rna splicingGO:0043484690.029
cell cycle arrestGO:000705040.029
negative regulation of gene expression epigeneticGO:0045814770.029
imaginal disc derived appendage developmentGO:00487373990.028
nucleoside metabolic processGO:00091161270.028
Human Yeast Worm
positive regulation of organelle organizationGO:0010638650.027
regulation of cell deathGO:00109411730.027
Worm
morphogenesis of follicular epitheliumGO:0016333360.027
negative regulation of signal transductionGO:00099682060.027
mapk cascadeGO:00001651070.027
cell proliferationGO:00082832990.026
mitotic g2 dna damage checkpointGO:0007095690.026
cytoplasmic transport nurse cell to oocyteGO:0007303120.026
positive regulation of apoptotic processGO:0043065470.025
positive regulation of mapk cascadeGO:0043410630.025
negative regulation of cell proliferationGO:0008285690.025
negative regulation of cell cycle g1 s phase transitionGO:1902807130.025
regulation of g1 s transition of mitotic cell cycleGO:2000045230.025
negative regulation of programmed cell deathGO:0043069720.025
Worm
response to endogenous stimulusGO:00097191190.024
negative regulation of multicellular organismal processGO:00512411420.024
regulation of mitotic cell cycle phase transitionGO:19019901300.024
rna interferenceGO:0016246270.024
locomotory behaviorGO:00076261760.024
response to organic substanceGO:00100332840.024
positive regulation of biosynthetic processGO:00098913160.024
regulation of programmed cell deathGO:00430671520.024
Worm
regulation of catabolic processGO:00098941700.023
protein complex assemblyGO:00064612000.023
Human
ovarian fusome organizationGO:0030723110.023
organonitrogen compound catabolic processGO:19015651280.023
Human Yeast Worm
dna packagingGO:0006323910.023
Worm
spindle organizationGO:00070512530.023
signal transduction by phosphorylationGO:00230141070.022
negative regulation of signalingGO:00230572190.022
regulation of cellular component biogenesisGO:00440872010.022
organonitrogen compound metabolic processGO:19015643180.022
Human Yeast Worm
mitotic g2 m transition checkpointGO:0044818700.022
dna dependent dna replicationGO:0006261170.022
Human
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.021
Worm
glycosyl compound metabolic processGO:19016571270.021
Human Yeast Worm
postreplication repairGO:000630120.021
dna catabolic processGO:0006308160.021
jak stat cascadeGO:0007259490.021
purine containing compound catabolic processGO:00725231120.020
Human Yeast Worm
mitotic cell cycle checkpointGO:0007093880.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
Human
protein localizationGO:00081042840.020
establishment of organelle localizationGO:00516561220.020
enzyme linked receptor protein signaling pathwayGO:00071671790.020
positive regulation of cell deathGO:0010942690.019
organelle assemblyGO:00709251980.019
chromatin silencingGO:0006342760.019
response to alkaloidGO:0043279260.019
nucleobase containing small molecule metabolic processGO:00550861740.019
Human Yeast Worm
purine ribonucleotide catabolic processGO:00091541090.019
Human Yeast Worm
nucleoside phosphate metabolic processGO:00067531620.018
Human Yeast Worm
positive regulation of catalytic activityGO:00430851180.018
negative regulation of cell differentiationGO:00455961430.018
regulation of mrna processingGO:0050684710.017
negative regulation of cell cycle processGO:00109481090.017
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.017
wing disc morphogenesisGO:00074723440.017
learning or memoryGO:00076111410.017
positive regulation of protein modification processGO:0031401580.016
intrinsic apoptotic signaling pathwayGO:0097193160.016
Worm
reproductive structure developmentGO:0048608740.016
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.016
rna splicingGO:0008380830.016
positive regulation of nucleic acid templated transcriptionGO:19035082660.015
regulation of growthGO:00400082330.015
purine ribonucleoside triphosphate metabolic processGO:00092051190.015
Human Yeast Worm
purine nucleoside triphosphate metabolic processGO:00091441190.015
Human Yeast Worm
regulation of phosphatase activityGO:001092130.015
intracellular mrna localization involved in pattern specification processGO:0060810560.015
cellular response to growth factor stimulusGO:0071363300.015
positive regulation of nitrogen compound metabolic processGO:00511733540.015
Human
mitotic recombinationGO:000631220.015
Yeast
dorsal ventral pattern formationGO:00099531330.015
nucleoside phosphate catabolic processGO:19012921100.015
Human Yeast Worm
genitalia developmentGO:0048806260.014
meiotic spindle organizationGO:0000212360.014
immune system processGO:00023763470.014
nucleoside triphosphate catabolic processGO:00091431080.014
Human Yeast Worm
mrna splicing via spliceosomeGO:0000398730.014
ubiquitin dependent protein catabolic processGO:0006511780.014
spindle assembly involved in meiosisGO:0090306200.014
forebrain developmentGO:003090020.014
cell maturationGO:00484691440.014
ribonucleoside metabolic processGO:00091191270.013
Human Yeast Worm
atp metabolic processGO:0046034490.013
Human Yeast Worm
glandular epithelial cell differentiationGO:000206710.013
protein maturationGO:0051604710.013
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.013
telomere organizationGO:0032200210.013
Yeast
g2 dna damage checkpointGO:0031572690.013
proteolysisGO:00065081920.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
negative regulation of phosphate metabolic processGO:0045936450.012
regulation of pole plasm oskar mrna localizationGO:0007317270.012
mrna catabolic processGO:0006402330.012
regulation of alternative mrna splicing via spliceosomeGO:0000381600.012
organophosphate catabolic processGO:00464341120.012
Human Yeast Worm
regulation of double strand break repairGO:200077930.012
appendage morphogenesisGO:00351073970.012
gonad developmentGO:0008406500.012
nuclear transcribed mrna catabolic processGO:0000956240.011
regulation of anatomical structure sizeGO:00900661630.011
oocyte microtubule cytoskeleton polarizationGO:0008103220.011
defense response to bacteriumGO:00427421780.011
positive regulation of rna metabolic processGO:00512542710.011
cell cycle dna replicationGO:0044786230.011
connective tissue developmentGO:006144830.011
cell cycle phase transitionGO:00447701400.011
positive regulation of cell proliferationGO:0008284470.011
sister chromatid cohesionGO:0007062180.011
jnk cascadeGO:0007254500.011
dna replication initiationGO:000627060.011
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018480.011
ribonucleotide catabolic processGO:00092611090.011
Human Yeast Worm
hematopoietic or lymphoid organ developmentGO:0048534570.011
posttranscriptional gene silencing by rnaGO:0035194450.011
glycerolipid catabolic processGO:004650330.010
peptidyl amino acid modificationGO:00181931050.010
positive regulation of developmental processGO:00510941430.010
membrane fusionGO:0061025420.010
positive regulation of transcription dna templatedGO:00458932660.010
cellular response to radiationGO:0071478520.010
Human
defense response to gram negative bacteriumGO:0050829940.010
regulation of protein modification processGO:00313991120.010
macromolecular complex assemblyGO:00650032560.010
Human
modification dependent protein catabolic processGO:0019941780.010
negative regulation of dna metabolic processGO:0051053120.010
regulation of multi organism processGO:00439001310.010
spermatogenesisGO:00072832000.010

spn-A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.077
Human
cancerDOID:16200.077
Human
organ system cancerDOID:005068600.032
Human
thoracic cancerDOID:509300.013
Human
disease of metabolismDOID:001466700.011