Drosophila melanogaster

120 known processes

opa (Dmel_CG1133)

odd paired

(Aliases: Dmel\CG1133,CG1133,Opa)

opa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.993
positive regulation of transcription dna templatedGO:00458932660.974
transcription from rna polymerase ii promoterGO:00063663680.949
central nervous system developmentGO:00074172010.926
Human Zebrafish Mouse
regulation of transcription from rna polymerase ii promoterGO:00063573780.922
positive regulation of nucleic acid templated transcriptionGO:19035082660.913
positive regulation of rna biosynthetic processGO:19026802660.905
digestive tract developmentGO:00485651490.902
tube developmentGO:00352952440.860
blastoderm segmentationGO:00073501590.843
positive regulation of rna metabolic processGO:00512542710.836
compound eye developmentGO:00487493070.808
regionalizationGO:00030024160.785
Zebrafish Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.778
negative regulation of transcription dna templatedGO:00458922370.777
Zebrafish Mouse Fly
segmentationGO:00352822070.776
epithelial cell differentiationGO:00308553220.735
embryonic pattern specificationGO:00098801740.733
morphogenesis of an epitheliumGO:00020092760.733
Human Zebrafish Mouse
stem cell differentiationGO:00488631170.715
Zebrafish
appendage morphogenesisGO:00351073970.710
compound eye photoreceptor cell differentiationGO:00017511400.705
negative regulation of nucleic acid templated transcriptionGO:19035072400.705
Zebrafish Mouse Fly
positive regulation of gene expressionGO:00106282900.688
cuticle developmentGO:0042335860.688
positive regulation of biosynthetic processGO:00098913160.685
digestive system developmentGO:00551231490.634
negative regulation of biosynthetic processGO:00098902770.620
Zebrafish Mouse Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.619
Zebrafish Mouse Fly
epithelial cell developmentGO:00020642740.610
positive regulation of cellular biosynthetic processGO:00313283160.584
foregut morphogenesisGO:0007440100.582
negative regulation of nucleobase containing compound metabolic processGO:00459342610.577
Zebrafish Mouse Fly
negative regulation of cellular biosynthetic processGO:00313272770.569
Zebrafish Mouse Fly
sensory organ morphogenesisGO:00905962600.527
Zebrafish
eye photoreceptor cell differentiationGO:00017541450.515
positive regulation of nitrogen compound metabolic processGO:00511733540.510
brain developmentGO:00074201200.497
Human Zebrafish Mouse
malpighian tubule developmentGO:0072002640.492
imaginal disc derived appendage developmentGO:00487373990.483
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.481
Zebrafish Mouse Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.478
Zebrafish Mouse Fly
head involutionGO:0008258350.476
renal system developmentGO:0072001720.461
appendage developmentGO:00487364010.448
negative regulation of gene expressionGO:00106293870.434
Zebrafish Mouse Fly
camera type eye developmentGO:004301040.427
Zebrafish
tube morphogenesisGO:00352391910.422
Human Zebrafish Mouse
columnar cuboidal epithelial cell developmentGO:00020662490.416
head segmentationGO:0035287130.414
head developmentGO:00603221350.395
Human Zebrafish Mouse
embryonic organ developmentGO:0048568500.383
Human Zebrafish Mouse
eye developmentGO:00016543230.382
Zebrafish
nephron epithelium developmentGO:007200930.378
positive regulation of macromolecule biosynthetic processGO:00105572830.369
renal tubule developmentGO:0061326640.363
eye antennal disc developmentGO:0035214600.347
epithelial tube morphogenesisGO:0060562880.341
Human Zebrafish Mouse
embryonic epithelial tube formationGO:000183860.340
Zebrafish Mouse
developmental programmed cell deathGO:00106231380.340
heart developmentGO:0007507820.339
Human Mouse
gland developmentGO:00487321910.337
Human
malpighian tubule morphogenesisGO:0007443440.336
segment specificationGO:0007379330.331
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.322
Fly
cellular protein modification processGO:00064644380.321
positive regulation of macromolecule metabolic processGO:00106044050.317
nephron tubule morphogenesisGO:007207830.314
regulation of organ morphogenesisGO:2000027780.303
leg disc developmentGO:0035218920.280
wing disc morphogenesisGO:00074723440.276
negative regulation of cellular metabolic processGO:00313243820.276
Zebrafish Mouse Fly
negative regulation of rna metabolic processGO:00512532510.273
Zebrafish Mouse Fly
digestive tract morphogenesisGO:00485461270.267
kidney developmentGO:000182230.265
regulation of embryonic developmentGO:0045995680.256
anterior posterior pattern specificationGO:00099521360.251
Zebrafish Mouse
dorsal closureGO:0007391790.247
nephron morphogenesisGO:007202830.247
periodic partitioningGO:0007365290.226
neural precursor cell proliferationGO:0061351750.225
Zebrafish
hindbrain developmentGO:003090220.223
Zebrafish
sex differentiationGO:0007548810.221
Worm
negative regulation of rna biosynthetic processGO:19026792400.220
Zebrafish Mouse Fly
columnar cuboidal epithelial cell differentiationGO:00020652560.220
respiratory system developmentGO:00605412130.220
Human
eye photoreceptor cell fate commitmentGO:0042706370.218
cellular response to chemical stimulusGO:00708871990.215
Fly
regulation of cell proliferationGO:00421271630.209
Zebrafish
negative regulation of cell differentiationGO:00455961430.208
compound eye photoreceptor developmentGO:0042051780.207
wnt signaling pathwayGO:0016055980.204
Zebrafish
embryonic morphogenesisGO:00485982060.186
Human Zebrafish Mouse
embryonic hemopoiesisGO:0035162260.185
regulation of wnt signaling pathwayGO:0030111680.182
cell proliferationGO:00082832990.181
Zebrafish
post embryonic appendage morphogenesisGO:00351203850.178
embryonic axis specificationGO:00005781070.178
compound eye photoreceptor fate commitmentGO:0001752360.171
stem cell proliferationGO:0072089880.165
kidney epithelium developmentGO:007207330.165
embryonic hindgut morphogenesisGO:0048619480.164
regulation of anatomical structure morphogenesisGO:00226032420.160
urogenital system developmentGO:0001655720.158
embryonic development via the syncytial blastodermGO:00017001480.157
connective tissue developmentGO:006144830.145
gastrulationGO:0007369700.144
photoreceptor cell fate commitmentGO:0046552410.143
compound eye morphogenesisGO:00017452490.142
chemosensory behaviorGO:00076351060.141
programmed cell deathGO:00125012570.141
morphogenesis of embryonic epitheliumGO:0016331940.136
Zebrafish Mouse
regulation of multicellular organismal developmentGO:20000264140.136
regulation of imaginal disc derived wing sizeGO:0044719200.133
axis specificationGO:00097981670.126
Zebrafish
regulation of epithelial cell differentiationGO:003085640.125
proximal distal pattern formationGO:0009954150.125
cardiac cell fate determinationGO:006091330.123
deathGO:00162652840.123
hindgut morphogenesisGO:0007442580.123
apoptotic process involved in morphogenesisGO:006056130.118
dendrite morphogenesisGO:00488131990.116
imaginal disc derived wing morphogenesisGO:00074763370.115
post embryonic hemopoiesisGO:0035166170.115
imaginal disc pattern formationGO:0007447910.113
dendrite developmentGO:00163582040.112
nephron epithelium morphogenesisGO:007208830.112
hindgut developmentGO:0061525580.112
chitin based cuticle developmentGO:0040003490.109
tripartite regional subdivisionGO:00073511030.109
reproductive system developmentGO:0061458740.109
Worm
regulation of heart morphogenesisGO:200082630.107
cell divisionGO:00513012480.105
cardiovascular system developmentGO:0072358820.105
Human Mouse
nephron tubule formationGO:007207930.103
salivary gland morphogenesisGO:00074351450.102
stem cell maintenanceGO:0019827670.102
positive regulation of programmed cell deathGO:0043068620.101
protein localizationGO:00081042840.101
Mouse
regulation of embryonic cell shapeGO:0016476300.097
negative regulation of cell cycle processGO:00109481090.096
ovarian follicle cell developmentGO:00307072480.095
photoreceptor cell differentiationGO:00465301700.092
axon developmentGO:00615642970.091
Mouse
specification of segmental identity headGO:0007380110.091
neuroblast fate commitmentGO:0014017190.089
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.089
Fly
mesenchymal cell differentiationGO:004876210.086
Zebrafish
tissue deathGO:00162711020.086
limb developmentGO:006017310.084
lymph gland developmentGO:0048542280.083
eye morphogenesisGO:00485922600.083
Zebrafish
neuron projection guidanceGO:00974852410.083
Mouse
cell fate commitment involved in formation of primary germ layerGO:0060795100.083
chromosome organizationGO:00512763600.081
spinal cord developmentGO:002151010.080
Zebrafish Mouse
renal tubule morphogenesisGO:0061333440.080
autophagyGO:00069141080.079
eye photoreceptor cell developmentGO:0042462810.079
imaginal disc derived female genitalia developmentGO:000748660.079
morphogenesis of a branching epitheliumGO:0061138450.078
compound eye retinal cell programmed cell deathGO:0046667230.078
tissue morphogenesisGO:00487292970.077
Human Zebrafish Mouse
kidney morphogenesisGO:006099330.077
reproductive structure developmentGO:0048608740.076
Worm
positive regulation of signal transductionGO:00099672230.075
imaginal disc derived leg morphogenesisGO:0007480800.075
regulation of stem cell proliferationGO:0072091400.073
development of primary sexual characteristicsGO:0045137500.073
Worm
cell deathGO:00082192790.071
cell cell signaling involved in cell fate commitmentGO:00451682100.070
retina development in camera type eyeGO:006004140.069
Zebrafish
endocytosisGO:00068973100.069
regulation of apoptotic processGO:00429811300.069
protein modification processGO:00362114380.067
regulation of molecular functionGO:00650092170.066
Mouse
dorsal ventral pattern formationGO:00099531330.066
Zebrafish
neuron recognitionGO:00080381010.065
neuron fate commitmentGO:0048663500.065
Worm
cell fate specificationGO:0001708710.065
Worm
salivary gland developmentGO:00074311620.064
negative regulation of cell deathGO:0060548810.064
nephron tubule developmentGO:007208030.063
tube formationGO:0035148210.062
Zebrafish Mouse
gland morphogenesisGO:00226121450.062
neuroblast differentiationGO:0014016290.062
olfactory behaviorGO:0042048970.061
morphogenesis of a polarized epitheliumGO:0001738930.060
exocrine system developmentGO:00352721620.059
nephron developmentGO:007200630.059
histolysisGO:00075591020.058
sex comb developmentGO:004549880.058
cellular component assembly involved in morphogenesisGO:00109271510.058
segment polarity determinationGO:0007367250.058
ectodermal placode morphogenesisGO:007169740.057
hemocyte differentiationGO:0042386380.057
epithelial tube formationGO:007217570.056
Zebrafish Mouse
positive regulation of wnt signaling pathwayGO:0030177250.056
axonogenesisGO:00074092900.055
Mouse
gonad developmentGO:0008406500.055
Worm
embryonic foregut morphogenesisGO:004861730.055
imaginal disc derived appendage morphogenesisGO:00351143950.054
regulation of cell cycleGO:00517262910.054
negative regulation of multicellular organismal processGO:00512411420.052
photoreceptor cell developmentGO:0042461960.052
epithelial cell migrationGO:00106311480.052
smoothened signaling pathwayGO:0007224490.051
Zebrafish Mouse
morphogenesis of a branching structureGO:0001763450.051
circulatory system developmentGO:0072359820.050
Human Mouse
vesicle mediated transportGO:00161923810.050
limb morphogenesisGO:003510810.050
regulation of cell differentiationGO:00455953020.050
positive regulation of cell deathGO:0010942690.049
imaginal disc derived leg segmentationGO:0036011260.048
internal protein amino acid acetylationGO:0006475380.048
branching morphogenesis of an epithelial tubeGO:0048754450.047
regulation of programmed cell deathGO:00430671520.047
negative regulation of wnt signaling pathwayGO:0030178280.045
telencephalon developmentGO:002153720.045
regulation of cell cycle processGO:00105641810.043
germ cell migrationGO:0008354430.043
synaptic transmissionGO:00072682880.043
cell migrationGO:00164772380.042
anterior posterior axis specificationGO:00099481090.042
Zebrafish
positive regulation of compound eye retinal cell programmed cell deathGO:004667290.041
chorion containing eggshell formationGO:00073041050.041
regulation of epithelial cell proliferationGO:005067840.041
negative regulation of developmental processGO:00510932010.041
neuroblast proliferationGO:0007405740.041
torso signaling pathwayGO:0008293210.040
growthGO:00400073590.040
anterior posterior axis specification embryoGO:00085951030.039
phagocytosisGO:00069092150.039
memoryGO:0007613940.038
cardioblast cell fate determinationGO:000751030.038
gastrulation involving germ band extensionGO:0010004360.037
establishment of ommatidial planar polarityGO:0042067490.037
immune system processGO:00023763470.037
regulation of cell deathGO:00109411730.036
neuron fate specificationGO:0048665120.036
Worm
retina morphogenesis in camera type eyeGO:006004220.035
Zebrafish
dorsal appendage formationGO:0046843470.035
neurological system processGO:00508773580.035
Mouse
mesodermal cell fate specificationGO:000750120.035
posterior head segmentationGO:003528960.034
localization of cellGO:00516742570.034
convergent extensionGO:006002620.034
regulation of compound eye retinal cell programmed cell deathGO:0046669180.034
response to gravityGO:0009629260.034
ovarian follicle cell migrationGO:00072971210.033
cellular response to organic substanceGO:00713101320.033
catabolic processGO:00090564090.033
regulation of retinal cell programmed cell deathGO:0046668180.032
cuticle pattern formationGO:0035017270.032
camera type eye morphogenesisGO:004859320.032
Zebrafish
endodermal cell fate commitmentGO:000171130.032
cell cycle dna replicationGO:0044786230.031
developmental inductionGO:003112830.031
midgut developmentGO:0007494230.031
salivary gland histolysisGO:0035070880.031
imaginal disc derived wing margin morphogenesisGO:0008587410.031
regulation of anatomical structure sizeGO:00900661630.031
negative regulation of cell cycleGO:00457861160.031
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.030
embryo development ending in birth or egg hatchingGO:00097921520.030
Zebrafish Mouse
stem cell developmentGO:0048864790.029
Zebrafish
response to organic substanceGO:00100332840.029
larval lymph gland hemopoiesisGO:0035167170.028
zygotic determination of anterior posterior axis embryoGO:0007354270.028
wing disc pattern formationGO:0035222660.028
regulation of phosphorus metabolic processGO:00511742100.028
positive regulation of retinal cell programmed cell deathGO:004667090.027
locomotory behaviorGO:00076261760.027
Mouse
eggshell formationGO:00307031050.026
retinal cell programmed cell deathGO:0046666250.026
regulation of neural precursor cell proliferationGO:2000177350.026
motor neuron axon guidanceGO:0008045580.026
regulation of tube sizeGO:0035150460.026
immune system developmentGO:0002520570.026
cell cycle checkpointGO:0000075950.026
response to endogenous stimulusGO:00097191190.025
positive regulation of epithelial cell differentiationGO:003085810.025
response to oxygen containing compoundGO:19017002000.025
organic substance catabolic processGO:19015753080.025
brain morphogenesisGO:0048854160.025
Zebrafish
mesenchyme developmentGO:006048590.025
Zebrafish
embryonic heart tube developmentGO:0035050220.025
Human Mouse
dorsal ventral pattern formation imaginal discGO:0007450510.025
organonitrogen compound metabolic processGO:19015643180.025
cell cycle comprising mitosis without cytokinesisGO:0033301250.025
terminal region determinationGO:0007362250.024
positive regulation of developmental processGO:00510941430.024
mesenchymal cell developmentGO:001403110.024
Zebrafish
induction of programmed cell death by hormonesGO:0035081120.024
autophagic cell deathGO:0048102830.024
negative regulation of epithelial cell proliferationGO:005068040.024
positive regulation of cell proliferationGO:0008284470.023
ventral midline developmentGO:000741890.023
larval lymph gland hemocyte differentiationGO:0035168110.023
determination of left right symmetryGO:000736890.023
Human Zebrafish Mouse
r7 cell differentiationGO:0045466430.023
apoptotic process involved in developmentGO:1902742200.023
taxisGO:00423303040.022
Mouse
r3 r4 cell fate commitmentGO:0007464100.022
negative regulation of apoptotic processGO:0043066630.022
endoderm formationGO:000170630.022
regulation of phosphatase activityGO:001092130.022
pigmentationGO:0043473750.022
Mouse
adipose tissue developmentGO:006061220.021
ameboidal type cell migrationGO:00016671510.021
establishment or maintenance of bipolar cell polarityGO:0061245340.021
syncytial blastoderm mitotic cell cycleGO:0035186210.021
response to growth factorGO:0070848310.021
cell cycle phase transitionGO:00447701400.020
organelle assemblyGO:00709251980.020
mapk cascadeGO:00001651070.020
regulation of cellular protein metabolic processGO:00322682430.020
body morphogenesisGO:001017120.020
regulation of organ formationGO:000315630.020
digestive tract mesoderm developmentGO:000750250.020
phosphorylationGO:00163102940.020
regulation of phosphorylationGO:00423251470.019
establishment or maintenance of cell polarityGO:00071631670.019
regulation of cell divisionGO:0051302720.019
stem cell fate commitmentGO:0048865250.019
negative regulation of response to stimulusGO:00485852580.019
ectodermal placode formationGO:006078840.019
dna endoreduplicationGO:0042023220.019
negative regulation of neural precursor cell proliferationGO:2000178270.019
somatic stem cell maintenanceGO:0035019140.018
induction of programmed cell death by ecdysoneGO:0035078120.018
eggshell chorion assemblyGO:0007306660.018
response to sterolGO:0036314340.018
leg disc morphogenesisGO:0007478800.018
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.018
cardioblast cell fate commitmentGO:0042684140.018
regulation of protein modification processGO:00313991120.018
regulation of cell cycle phase transitionGO:19019871300.018
tissue migrationGO:00901301550.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.017
positive regulation of response to stimulusGO:00485843230.017
muscle cell fate commitmentGO:0042693140.017
cellular catabolic processGO:00442483720.017
equator specificationGO:004531740.017
neural retina developmentGO:000340740.017
endoderm developmentGO:000749260.017
regulation of mitotic cell cycle phase transitionGO:19019901300.017
negative regulation of programmed cell deathGO:0043069720.017
ectodermal placode developmentGO:007169640.017
r7 cell developmentGO:0045467140.017
response to ecdysoneGO:0035075340.017
response to lipidGO:0033993380.016
positive regulation of cell motilityGO:200014730.016
mitotic dna integrity checkpointGO:0044774750.016
specification of organ identityGO:001009230.016
mitotic spindle organizationGO:00070522200.016
cell motilityGO:00488702510.016
pericardial nephrocyte differentiationGO:006132090.016
endodermal cell differentiationGO:003598730.016
regulation of cell fate commitmentGO:0010453290.016
embryonic organ morphogenesisGO:004856250.015
Human Zebrafish Mouse
mesodermal cell fate commitmentGO:000171070.015
positive regulation of mapk cascadeGO:0043410630.015
male genitalia developmentGO:0030539190.015
response to biotic stimulusGO:00096072940.015
amnioserosa maintenanceGO:004666550.015
positive regulation of stem cell differentiationGO:200073830.015
positive regulation of signalingGO:00230562430.015
negative regulation of cell developmentGO:0010721620.014
female genitalia developmentGO:003054060.014
muscle cell differentiationGO:00426921030.014
regulation of mapk cascadeGO:0043408920.014
developmental growthGO:00485892800.014
morphogenesis of follicular epitheliumGO:0016333360.014
negative regulation of cell proliferationGO:0008285690.014
negative regulation of neurogenesisGO:0050768530.014
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.014
cardioblast differentiationGO:0010002200.014
negative regulation of mitotic cell cycle phase transitionGO:19019911030.014
regulation of phosphate metabolic processGO:00192202100.014
stem cell fate specificationGO:004886620.014
regulation of muscle cell differentiationGO:005114780.013
axon guidanceGO:00074112330.013
Mouse
mesodermal cell differentiationGO:004833370.013
adult behaviorGO:00305341370.013
Mouse
forebrain developmentGO:003090020.013
Zebrafish Mouse
regulation of cellular amine metabolic processGO:003323830.013
spindle organizationGO:00070512530.013
response to alcoholGO:0097305950.013
branch fusion open tracheal systemGO:0035147170.013
positive regulation of intracellular signal transductionGO:19025331160.013
single organism intracellular transportGO:19025822070.013
Mouse
molting cycleGO:0042303560.013
positive regulation of phosphorus metabolic processGO:00105621390.013
negative regulation of signalingGO:00230572190.013
negative regulation of molecular functionGO:0044092510.013
regulation of bindingGO:0051098160.013
genitalia developmentGO:0048806260.012
Worm
apoptotic processGO:00069151590.012
negative regulation of signal transductionGO:00099682060.012
neuroblast fate specificationGO:001401820.012
cellular response to oxygen containing compoundGO:1901701790.012
establishment of tissue polarityGO:0007164870.012
chaeta developmentGO:0022416970.012
molting cycle chitin based cuticleGO:0007591560.012
proteolysisGO:00065081920.012
cellular amine metabolic processGO:0044106120.012
aggressive behaviorGO:0002118630.012
germarium derived egg chamber formationGO:00072931010.012
optic placode formationGO:000174340.012
positive regulation of cell communicationGO:00106472500.012
r3 r4 cell differentiationGO:0048056120.012
hematopoietic or lymphoid organ developmentGO:0048534570.012
skin developmentGO:0043588650.012
positive regulation of erk1 and erk2 cascadeGO:0070374360.012
positive regulation of multicellular organismal processGO:00512401430.012
cellular amino acid metabolic processGO:0006520610.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
organ formationGO:0048645390.012
positive regulation of cell migrationGO:003033520.011
cardiac cell fate commitmentGO:0060911170.011
negative regulation of cell communicationGO:00106482230.011
negative regulation of proteolysisGO:0045861310.011
lipid metabolic processGO:00066291210.011
negative regulation of nervous system developmentGO:0051961920.011
protein localization to nucleusGO:0034504550.011
Mouse
synaptic target recognitionGO:0008039450.011
male sex differentiationGO:0046661250.011
establishment of planar polarityGO:0001736870.011
cell growthGO:00160491080.011
maintenance of gastrointestinal epitheliumGO:003027730.011
cellular ketone metabolic processGO:0042180240.011
cellular response to fibroblast growth factor stimulusGO:0044344100.011
neuroblast developmentGO:0014019130.011
protein transportGO:00150311550.011
Mouse
regulation of mitosisGO:0007088560.011
epithelial cell proliferationGO:0050673150.011
regulation of reproductive processGO:2000241540.010
notch signaling pathwayGO:00072191200.010
cell surface receptor signaling pathway involved in heart developmentGO:006131130.010
regulation of cell fate specificationGO:0042659270.010
response to external biotic stimulusGO:00432072930.010
fibroblast growth factor receptor signaling pathwayGO:0008543100.010
response to woundingGO:0009611940.010
positive regulation of catalytic activityGO:00430851180.010
negative regulation of cellular component organizationGO:00511291080.010

opa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.113
cancerDOID:16200.113
organ system cancerDOID:005068600.102
disease of anatomical entityDOID:700.014
sensory system diseaseDOID:005015500.014
nervous system diseaseDOID:86300.014
musculoskeletal system diseaseDOID:1700.013