IMP: Integrative Multi-species Prediction

Drosophila melanogaster

31 known processes

pen (Dmel_CG1685)

penguin

(Aliases: CG1685,Dmel\CG1685)

Entrez: 33112
FLYBASE: FBgn0015527
UniProtKB: O61345

Process Predictions
Disease Predictions

pen biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
meiotic nuclear division	GO:0007126	151	0.089
organelle fission	GO:0048285	340	0.082
nuclear division	GO:0000280	332	0.073
centrosome duplication	GO:0051298	121	0.065
establishment of localization in cell	GO:0051649	402	0.064
cellular macromolecule localization	GO:0070727	220	0.057
organonitrogen compound metabolic process	GO:1901564	318	0.052
catabolic process	GO:0009056	409	0.050
cellular protein modification process	GO:0006464	438	0.045
cellular response to dna damage stimulus	GO:0006974	223	0.043
centrosome organization	GO:0051297	163	0.043
regulation of cell cycle	GO:0051726	291	0.041
protein modification process	GO:0036211	438	0.040
vesicle mediated transport	GO:0016192	381	0.040
protein localization	GO:0008104	284	0.040
nucleobase containing compound catabolic process	GO:0034655	165	0.037
cell division	GO:0051301	248	0.037
centrosome cycle	GO:0007098	137	0.036
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.036
modification dependent macromolecule catabolic process	GO:0043632	79	0.036
cellular macromolecular complex assembly	GO:0034622	153	0.035
small molecule metabolic process	GO:0044281	305	0.031
carbohydrate derivative metabolic process	GO:1901135	217	0.031
organic substance catabolic process	GO:1901575	308	0.030
negative regulation of transcription dna templated	GO:0045892	237	0.030
mitotic nuclear division	GO:0007067	213	0.030
endocytosis	GO:0006897	310	0.029
chromosome segregation	GO:0007059	157	0.029
cellular catabolic process	GO:0044248	372	0.028
oxoacid metabolic process	GO:0043436	103	0.028
embryo development ending in birth or egg hatching	GO:0009792	152	0.027
negative regulation of biosynthetic process	GO:0009890	277	0.027
negative regulation of cellular metabolic process	GO:0031324	382	0.027
positive regulation of response to stimulus	GO:0048584	323	0.026
single organism catabolic process	GO:0044712	228	0.025
cell proliferation	GO:0008283	299	0.025
chromatin modification	GO:0016568	147	0.025
organelle localization	GO:0051640	148	0.024
organic acid metabolic process	GO:0006082	103	0.023
posttranscriptional regulation of gene expression	GO:0010608	145	0.023
protein catabolic process	GO:0030163	101	0.022
negative regulation of rna biosynthetic process	GO:1902679	240	0.022
spindle assembly	GO:0051225	80	0.022
cytoskeleton dependent cytokinesis	GO:0061640	81	0.021
mitotic sister chromatid segregation	GO:0000070	87	0.021
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.021
imaginal disc derived appendage development	GO:0048737	399	0.021
negative regulation of gene expression	GO:0010629	387	0.020
cellular macromolecule catabolic process	GO:0044265	136	0.020
response to abiotic stimulus	GO:0009628	341	0.020
mitotic cytokinesis	GO:0000281	50	0.019
cell motility	GO:0048870	251	0.019
phagocytosis	GO:0006909	215	0.019
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.019
positive regulation of cell communication	GO:0010647	250	0.019
response to biotic stimulus	GO:0009607	294	0.019
regulation of cell morphogenesis	GO:0022604	163	0.019
proteolysis	GO:0006508	192	0.018
cytokinesis	GO:0000910	90	0.018
establishment or maintenance of cell polarity	GO:0007163	167	0.018
sister chromatid segregation	GO:0000819	92	0.018
regulation of catabolic process	GO:0009894	170	0.018
chromatin organization	GO:0006325	207	0.018
covalent chromatin modification	GO:0016569	106	0.018
cellular protein localization	GO:0034613	160	0.018
cellular component assembly involved in morphogenesis	GO:0010927	151	0.017
cellular amine metabolic process	GO:0044106	12	0.017
regulation of cell development	GO:0060284	215	0.017
establishment of organelle localization	GO:0051656	122	0.017
response to oxygen containing compound	GO:1901700	200	0.017
chromosome organization	GO:0051276	360	0.017
heterocycle catabolic process	GO:0046700	166	0.017
organic substance transport	GO:0071702	257	0.017
mitotic spindle organization	GO:0007052	220	0.017
peptidyl amino acid modification	GO:0018193	105	0.017
dendrite development	GO:0016358	204	0.017
microtubule organizing center organization	GO:0031023	168	0.017
meiotic cell cycle	GO:0051321	171	0.016
single organism cellular localization	GO:1902580	180	0.016
positive regulation of signaling	GO:0023056	243	0.015
positive regulation of biosynthetic process	GO:0009891	316	0.015
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.015
tissue morphogenesis	GO:0048729	297	0.015
regulation of growth	GO:0040008	233	0.015
spindle organization	GO:0007051	253	0.015
embryonic development via the syncytial blastoderm	GO:0001700	148	0.015
carboxylic acid metabolic process	GO:0019752	92	0.015
cellular amino acid metabolic process	GO:0006520	61	0.015
regulation of localization	GO:0032879	275	0.015
male meiosis	GO:0007140	52	0.015
protein complex assembly	GO:0006461	200	0.015
ribonucleotide metabolic process	GO:0009259	145	0.015
reproductive system development	GO:0061458	74	0.015
programmed cell death	GO:0012501	257	0.015
growth	GO:0040007	359	0.015
regulation of meiosis	GO:0040020	3	0.015
macromolecular complex assembly	GO:0065003	256	0.015
cell migration	GO:0016477	238	0.014
regulation of cell cycle process	GO:0010564	181	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.014
protein dna complex subunit organization	GO:0071824	86	0.014
intracellular transport	GO:0046907	228	0.014
intracellular signal transduction	GO:0035556	300	0.014
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.014
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.014
regulation of anatomical structure morphogenesis	GO:0022603	242	0.014
protein phosphorylation	GO:0006468	169	0.014
organelle assembly	GO:0070925	198	0.014
single organism intracellular transport	GO:1902582	207	0.014
regulation of cell division	GO:0051302	72	0.014
mrna processing	GO:0006397	104	0.014
regulation of multicellular organismal development	GO:2000026	414	0.014
response to other organism	GO:0051707	293	0.014
negative regulation of cell communication	GO:0010648	223	0.013
rna processing	GO:0006396	147	0.013
actin filament based process	GO:0030029	220	0.013
body morphogenesis	GO:0010171	2	0.013
protein complex biogenesis	GO:0070271	201	0.013
regulation of nervous system development	GO:0051960	248	0.013
regulation of cell differentiation	GO:0045595	302	0.013
locomotory behavior	GO:0007626	176	0.013
muscle organ development	GO:0007517	127	0.013
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013
mrna metabolic process	GO:0016071	124	0.013
regulation of organelle organization	GO:0033043	196	0.013
histone modification	GO:0016570	106	0.013
cellular nitrogen compound catabolic process	GO:0044270	165	0.013
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.013
dna conformation change	GO:0071103	105	0.013
rna localization	GO:0006403	115	0.013
negative regulation of mitotic cell cycle	GO:0045930	109	0.013
cellularization	GO:0007349	90	0.013
male gamete generation	GO:0048232	201	0.013
morphogenesis of an epithelium	GO:0002009	276	0.012
tube morphogenesis	GO:0035239	191	0.012
leg disc morphogenesis	GO:0007478	80	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
nucleus organization	GO:0006997	45	0.012
regulation of catalytic activity	GO:0050790	185	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.012
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.012
amine metabolic process	GO:0009308	12	0.012
regionalization	GO:0003002	416	0.012
rna transport	GO:0050658	46	0.012
spindle elongation	GO:0051231	83	0.012
regulation of phosphorus metabolic process	GO:0051174	210	0.012
transcription from rna polymerase ii promoter	GO:0006366	368	0.012
dna metabolic process	GO:0006259	227	0.012
organophosphate metabolic process	GO:0019637	195	0.012
chromatin assembly or disassembly	GO:0006333	52	0.012
developmental maturation	GO:0021700	172	0.012
ribose phosphate metabolic process	GO:0019693	145	0.012
eye development	GO:0001654	323	0.012
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.011
cell death	GO:0008219	279	0.011
positive regulation of cellular biosynthetic process	GO:0031328	316	0.011
camera type eye development	GO:0043010	4	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.011
establishment of protein localization	GO:0045184	163	0.011
central nervous system development	GO:0007417	201	0.011
nuclear import	GO:0051170	51	0.011
apoptotic process	GO:0006915	159	0.011
muscle structure development	GO:0061061	224	0.011
regulation of transport	GO:0051049	181	0.011
humoral immune response	GO:0006959	117	0.010
mitotic dna damage checkpoint	GO:0044773	74	0.010
positive regulation of signal transduction	GO:0009967	223	0.010
cellular component disassembly	GO:0022411	46	0.010
positive regulation of macromolecule metabolic process	GO:0010604	405	0.010
purine containing compound metabolic process	GO:0072521	155	0.010
nucleoside phosphate metabolic process	GO:0006753	162	0.010
regulation of molecular function	GO:0065009	217	0.010
nucleocytoplasmic transport	GO:0006913	72	0.010

pen disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.054
	nervous system disease	DOID:863	0	0.021

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