IMP: Integrative Multi-species Prediction

Drosophila melanogaster

71 known processes

RpS3 (Dmel_CG6779)

Ribosomal protein S3

(Aliases: S3,RpS,rpS3,DmRpS3,X72921,M(3)B,RS3,M(3)B2,M(3)w,M(3)124,M(3)95A,M[[w]],M95A,dS3,Mw,Rps3,Dmel\CG6779,CG6779,M(3R)w,6779,rps3,M(3)Fla)

Entrez: 42761
FLYBASE: FBgn0002622
UniProtKB: Q06559
UniProtKB: G3M3A2

Process Predictions
Disease Predictions

RpS3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
determination of adult lifespan	GO:0008340	137	0.632	Worm
nuclear division	GO:0000280	332	0.495
establishment of localization in cell	GO:0051649	402	0.429	Yeast
purine containing compound catabolic process	GO:0072523	112	0.301
morphogenesis of an epithelium	GO:0002009	276	0.284
response to organic cyclic compound	GO:0014070	89	0.210
heart process	GO:0003015	37	0.210
mitotic nuclear division	GO:0007067	213	0.172
regulation of cell death	GO:0010941	173	0.163
nucleotide catabolic process	GO:0009166	109	0.160
death	GO:0016265	284	0.150
chitin based cuticle development	GO:0040003	49	0.139
homeostatic process	GO:0042592	199	0.127	Zebrafish
tissue death	GO:0016271	102	0.123
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.108
cuticle development	GO:0042335	86	0.101
spermatogenesis	GO:0007283	200	0.100
chemical homeostasis	GO:0048878	92	0.099
small molecule biosynthetic process	GO:0044283	37	0.098
cell death	GO:0008219	279	0.090
apoptotic process	GO:0006915	159	0.079
mitotic spindle organization	GO:0007052	220	0.078
embryo development ending in birth or egg hatching	GO:0009792	152	0.072	Worm
positive regulation of gene expression	GO:0010628	290	0.070
blood circulation	GO:0008015	26	0.069
negative regulation of programmed cell death	GO:0043069	72	0.068
synaptic growth at neuromuscular junction	GO:0051124	119	0.067
positive regulation of macromolecule metabolic process	GO:0010604	405	0.063
muscle system process	GO:0003012	21	0.060
male gamete generation	GO:0048232	201	0.048
regulation of heart contraction	GO:0008016	21	0.047
negative regulation of rna metabolic process	GO:0051253	251	0.047
regulation of reactive oxygen species metabolic process	GO:2000377	8	0.047
aromatic compound catabolic process	GO:0019439	166	0.047
spindle elongation	GO:0051231	83	0.046
muscle contraction	GO:0006936	13	0.046
body morphogenesis	GO:0010171	2	0.046
response to hexose	GO:0009746	3	0.044
single organism catabolic process	GO:0044712	228	0.042
nuclear export	GO:0051168	24	0.041	Yeast
response to glucose	GO:0009749	2	0.041
regulation of stem cell differentiation	GO:2000736	14	0.039
organonitrogen compound catabolic process	GO:1901565	128	0.039
negative regulation of cell death	GO:0060548	81	0.039
ribonucleotide catabolic process	GO:0009261	109	0.039
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.038
spindle organization	GO:0007051	253	0.038
actin filament based process	GO:0030029	220	0.037
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.037
histolysis	GO:0007559	102	0.035
regulation of apoptotic process	GO:0042981	130	0.035
nuclear transport	GO:0051169	72	0.032	Yeast
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.032
posttranscriptional regulation of gene expression	GO:0010608	145	0.032
purine ribonucleotide catabolic process	GO:0009154	109	0.031
programmed cell death	GO:0012501	257	0.031
purine nucleoside catabolic process	GO:0006152	112	0.030
striated muscle contraction	GO:0006941	5	0.030
neuron apoptotic process	GO:0051402	17	0.030
stem cell differentiation	GO:0048863	117	0.029
eggshell formation	GO:0030703	105	0.029
regulation of catabolic process	GO:0009894	170	0.029
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.028
regulation of cell differentiation	GO:0045595	302	0.027
cellular response to dna damage stimulus	GO:0006974	223	0.027
regulation of programmed cell death	GO:0043067	152	0.026
female germ line stem cell asymmetric division	GO:0048132	14	0.025
germline stem cell asymmetric division	GO:0098728	15	0.024
translation	GO:0006412	69	0.024
taxis	GO:0042330	304	0.024
developmental programmed cell death	GO:0010623	138	0.023
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.023
purine ribonucleoside catabolic process	GO:0046130	112	0.022
regulation of response to stress	GO:0080134	200	0.022	Human
eye antennal disc morphogenesis	GO:0007455	34	0.022
positive regulation of phosphate metabolic process	GO:0045937	139	0.022
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.022
organic substance transport	GO:0071702	257	0.022	Yeast
cellular catabolic process	GO:0044248	372	0.021
cellular response to external stimulus	GO:0071496	66	0.021
carbohydrate derivative catabolic process	GO:1901136	118	0.020
maintenance of gastrointestinal epithelium	GO:0030277	3	0.020
positive regulation of cellular biosynthetic process	GO:0031328	316	0.020
positive regulation of translation	GO:0045727	12	0.020
purine nucleotide catabolic process	GO:0006195	109	0.020
positive regulation of transcription dna templated	GO:0045893	266	0.020
cellular protein modification process	GO:0006464	438	0.019
positive regulation of developmental growth	GO:0048639	62	0.019
cellular response to oxygen containing compound	GO:1901701	79	0.019
defense response	GO:0006952	300	0.018
regulation of nucleoside metabolic process	GO:0009118	50	0.017
response to endogenous stimulus	GO:0009719	119	0.017
nitrogen compound transport	GO:0071705	85	0.017	Yeast
retina development in camera type eye	GO:0060041	4	0.017
regulation of stem cell proliferation	GO:0072091	40	0.017
multicellular organism growth	GO:0035264	46	0.017
establishment of protein localization	GO:0045184	163	0.017
hindgut development	GO:0061525	58	0.017
regulation of intracellular signal transduction	GO:1902531	236	0.016
atp catabolic process	GO:0006200	38	0.016
nucleoside catabolic process	GO:0009164	112	0.016
organelle fission	GO:0048285	340	0.016
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.016
positive regulation of phosphorus metabolic process	GO:0010562	139	0.016
negative regulation of neuron apoptotic process	GO:0043524	14	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.015
regulation of localization	GO:0032879	275	0.015
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.015
cell type specific apoptotic process	GO:0097285	38	0.015
cellular response to oxidative stress	GO:0034599	28	0.015
exocrine system development	GO:0035272	162	0.015
stem cell development	GO:0048864	79	0.014
mrna processing	GO:0006397	104	0.014
positive regulation of rna biosynthetic process	GO:1902680	266	0.014
germ line stem cell maintenance	GO:0030718	50	0.013
chromosome condensation	GO:0030261	41	0.013
purine ribonucleotide metabolic process	GO:0009150	145	0.013
nephron tubule morphogenesis	GO:0072078	3	0.013
regulation of ras protein signal transduction	GO:0046578	93	0.013
organophosphate catabolic process	GO:0046434	112	0.013
positive regulation of molecular function	GO:0044093	136	0.013	Human
regulation of nervous system development	GO:0051960	248	0.013
spermatid differentiation	GO:0048515	114	0.013
response to oxygen containing compound	GO:1901700	200	0.013
regulation of blood circulation	GO:1903522	21	0.012
heterocycle catabolic process	GO:0046700	166	0.012
imaginal disc growth	GO:0007446	37	0.012
protein transport	GO:0015031	155	0.012
nucleoside metabolic process	GO:0009116	127	0.012
purine containing compound metabolic process	GO:0072521	155	0.012
mitotic sister chromatid segregation	GO:0000070	87	0.012
regulation of insulin like growth factor receptor signaling pathway	GO:0043567	3	0.012
response to mechanical stimulus	GO:0009612	28	0.012
negative regulation of stem cell proliferation	GO:2000647	30	0.012
regulation of purine nucleotide metabolic process	GO:1900542	62	0.012
translational elongation	GO:0006414	4	0.011
larval midgut cell programmed cell death	GO:0035096	19	0.011
circulatory system process	GO:0003013	37	0.011
negative regulation of apoptotic process	GO:0043066	63	0.011
vesicle mediated transport	GO:0016192	381	0.011
salivary gland development	GO:0007431	162	0.011
nucleobase containing compound catabolic process	GO:0034655	165	0.011
autophagic cell death	GO:0048102	83	0.011
salivary gland histolysis	GO:0035070	88	0.011
regulation of multicellular organismal development	GO:2000026	414	0.011
salivary gland morphogenesis	GO:0007435	145	0.011
regulation of muscle contraction	GO:0006937	5	0.010
post embryonic appendage morphogenesis	GO:0035120	385	0.010
single organism behavior	GO:0044708	391	0.010
regulation of phosphatase activity	GO:0010921	3	0.010

RpS3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
hematopoietic system disease	DOID:74	0.032
anemia	DOID:2355	0.032
bone marrow disease	DOID:4961	0.032
disease of anatomical entity	DOID:7	0.032
aplastic anemia	DOID:12449	0.032
congenital hypoplastic anemia	DOID:1342	0.032
immune system disease	DOID:2914	0.032
nervous system disease	DOID:863	0.027
sensory system disease	DOID:0050155	0.011

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