Drosophila melanogaster

160 known processes

pygo (Dmel_CG11518)

pygopus

(Aliases: pyg,Dmel\CG11518,anon-WO02077023.1,BEST:LD21971,gam,pypo,CG11518,pNB5.2,dPygo,Pygo)

pygo biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycleGO:00517262910.842
chromosome organizationGO:00512763600.836
protein modification processGO:00362114380.806
regulation of transcription from rna polymerase ii promoterGO:00063573780.774
axon developmentGO:00615642970.705
cellular protein modification processGO:00064644380.623
establishment of organelle localizationGO:00516561220.595
negative regulation of cell communicationGO:00106482230.557
imaginal disc derived leg morphogenesisGO:0007480800.555
appendage developmentGO:00487364010.523
regulation of neurogenesisGO:00507671580.493
regulation of wnt signaling pathwayGO:0030111680.492
post embryonic appendage morphogenesisGO:00351203850.490
negative regulation of rna metabolic processGO:00512532510.410
positive regulation of rna metabolic processGO:00512542710.407
imaginal disc derived appendage developmentGO:00487373990.401
negative regulation of signal transductionGO:00099682060.390
wing disc morphogenesisGO:00074723440.361
negative regulation of response to stimulusGO:00485852580.358
negative regulation of nucleic acid templated transcriptionGO:19035072400.350
transcription from rna polymerase ii promoterGO:00063663680.349
chromatin organizationGO:00063252070.342
rna processingGO:00063961470.314
negative regulation of nucleobase containing compound metabolic processGO:00459342610.312
negative regulation of macromolecule biosynthetic processGO:00105582700.305
positive regulation of nucleic acid templated transcriptionGO:19035082660.297
eye developmentGO:00016543230.296
intracellular transportGO:00469072280.282
regulation of anatomical structure morphogenesisGO:00226032420.279
imaginal disc derived appendage morphogenesisGO:00351143950.277
regionalizationGO:00030024160.273
imaginal disc derived wing margin morphogenesisGO:0008587410.268
stem cell developmentGO:0048864790.263
regulation of multicellular organismal developmentGO:20000264140.255
axonogenesisGO:00074092900.243
regulation of developmental pigmentationGO:0048070240.241
establishment of localization in cellGO:00516494020.237
positive regulation of nitrogen compound metabolic processGO:00511733540.229
single organism cellular localizationGO:19025801800.226
periodic partitioningGO:0007365290.223
blastoderm segmentationGO:00073501590.219
regulation of nervous system developmentGO:00519602480.210
negative regulation of biosynthetic processGO:00098902770.209
cellular response to dna damage stimulusGO:00069742230.207
anterior posterior pattern specificationGO:00099521360.206
axon guidanceGO:00074112330.202
leg disc morphogenesisGO:0007478800.202
organelle localizationGO:00516401480.201
appendage morphogenesisGO:00351073970.196
cell cycle phase transitionGO:00447701400.192
segmentationGO:00352822070.181
regulation of mitotic cell cycle phase transitionGO:19019901300.180
regulation of programmed cell deathGO:00430671520.178
negative regulation of signalingGO:00230572190.177
negative regulation of wnt signaling pathwayGO:0030178280.159
response to nitrogen compoundGO:1901698900.158
positive regulation of response to stimulusGO:00485843230.157
circulatory system developmentGO:0072359820.156
segment polarity determinationGO:0007367250.153
posttranscriptional regulation of gene expressionGO:00106081450.152
leg disc developmentGO:0035218920.147
forebrain developmentGO:003090020.145
peptidyl amino acid modificationGO:00181931050.143
negative regulation of nitrogen compound metabolic processGO:00511722650.142
negative regulation of cellular metabolic processGO:00313243820.139
regulation of protein modification processGO:00313991120.137
negative regulation of cellular biosynthetic processGO:00313272770.125
covalent chromatin modificationGO:00165691060.123
g2 dna damage checkpointGO:0031572690.121
positive regulation of protein metabolic processGO:00512471280.121
regulation of protein transportGO:0051223570.121
cardiovascular system developmentGO:0072358820.120
mitotic cell cycle phase transitionGO:00447721380.118
regulation of cellular localizationGO:00603411360.117
cell motilityGO:00488702510.116
imaginal disc pattern formationGO:0007447910.114
positive regulation of rna biosynthetic processGO:19026802660.112
endocytosisGO:00068973100.111
protein modification by small protein conjugation or removalGO:00706471060.111
regulation of eye pigmentationGO:004807370.111
neuron projection guidanceGO:00974852410.110
regulation of mitotic cell cycleGO:00073461900.107
protein localizationGO:00081042840.106
body morphogenesisGO:001017120.105
positive regulation of transcription dna templatedGO:00458932660.105
cell proliferationGO:00082832990.102
telencephalon developmentGO:002153720.102
regulation of cellular amine metabolic processGO:003323830.101
regulation of neuron differentiationGO:00456641030.101
modification dependent macromolecule catabolic processGO:0043632790.100
negative regulation of rna biosynthetic processGO:19026792400.100
embryo development ending in birth or egg hatchingGO:00097921520.098
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.097
neuroblast proliferationGO:0007405740.096
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.095
hindbrain developmentGO:003090220.092
embryonic pattern specificationGO:00098801740.090
appendage segmentationGO:0035285260.089
cuticle developmentGO:0042335860.089
chromatin modificationGO:00165681470.088
developmental growthGO:00485892800.086
regulation of phosphorylationGO:00423251470.086
histone modificationGO:00165701060.086
actin filament based processGO:00300292200.085
regulation of cell proliferationGO:00421271630.084
regulation of cell deathGO:00109411730.084
regulation of cellular ketone metabolic processGO:001056530.083
positive regulation of macromolecule metabolic processGO:00106044050.082
regulation of organelle organizationGO:00330431960.081
protein phosphorylationGO:00064681690.080
positive regulation of macromolecule biosynthetic processGO:00105572830.080
proteolysisGO:00065081920.080
protein ubiquitinationGO:0016567700.078
negative regulation of cytoskeleton organizationGO:0051494300.078
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.076
positive regulation of nucleobase containing compound metabolic processGO:00459353320.075
limb morphogenesisGO:003510810.075
stem cell differentiationGO:00488631170.075
central nervous system developmentGO:00074172010.072
regulation of cell developmentGO:00602842150.072
organic acid metabolic processGO:00060821030.071
tube developmentGO:00352952440.071
positive regulation of signal transductionGO:00099672230.070
larval developmentGO:00021641040.068
epithelial tube morphogenesisGO:0060562880.068
gene silencing by rnaGO:0031047570.067
proteasomal protein catabolic processGO:0010498590.067
developmental growth involved in morphogenesisGO:0060560650.067
positive regulation of gene expressionGO:00106282900.067
regulation of cell cycle phase transitionGO:19019871300.066
stem cell maintenanceGO:0019827670.064
negative regulation of epithelial cell proliferationGO:005068040.064
cell migrationGO:00164772380.064
negative regulation of developmental processGO:00510932010.062
actin cytoskeleton organizationGO:00300362060.062
tissue morphogenesisGO:00487292970.062
regulation of compound eye pigmentationGO:004807670.061
regulation of cellular amino acid metabolic processGO:000652100.060
regulation of developmental growthGO:00486381740.060
compound eye developmentGO:00487493070.060
single organism intracellular transportGO:19025822070.059
spindle organizationGO:00070512530.059
positive regulation of cellular component organizationGO:00511301560.058
positive regulation of biosynthetic processGO:00098913160.058
trachea developmentGO:0060438290.058
phosphorylationGO:00163102940.057
cellular protein localizationGO:00346131600.056
respiratory system developmentGO:00605412130.055
single organism behaviorGO:00447083910.055
canonical wnt signaling pathwayGO:0060070210.054
homeostatic processGO:00425921990.052
regulation of intracellular transportGO:0032386640.052
non canonical wnt signaling pathwayGO:003556780.052
oxoacid metabolic processGO:00434361030.051
ubiquitin dependent protein catabolic processGO:0006511780.051
digestive tract developmentGO:00485651490.051
maintenance of protein location in cellGO:0032507260.050
cellular amine metabolic processGO:0044106120.049
branching morphogenesis of an epithelial tubeGO:0048754450.049
protein modification by small protein conjugationGO:0032446790.049
brain developmentGO:00074201200.048
imaginal disc derived wing morphogenesisGO:00074763370.048
regulation of cytoplasmic transportGO:1903649470.046
smoothened signaling pathwayGO:0007224490.045
regulation of cellular protein metabolic processGO:00322682430.045
positive regulation of hh target transcription factor activityGO:000722850.044
posttranscriptional gene silencing by rnaGO:0035194450.043
negative regulation of mitotic cell cycle phase transitionGO:19019911030.043
intracellular signal transductionGO:00355563000.043
cellular amino acid metabolic processGO:0006520610.043
establishment of spindle localizationGO:0051293220.042
single organism membrane organizationGO:0044802930.042
regulation of cell cycle processGO:00105641810.041
protein localization to organelleGO:0033365820.040
synapse organizationGO:00508081960.039
cellular ketone metabolic processGO:0042180240.039
regulation of transportGO:00510491810.039
convergent extensionGO:006002620.039
regulation of epithelial cell proliferationGO:005067840.038
positive regulation of molecular functionGO:00440931360.038
response to external biotic stimulusGO:00432072930.037
immune system processGO:00023763470.037
tube morphogenesisGO:00352391910.037
regulation of cell differentiationGO:00455953020.037
regulation of intracellular signal transductionGO:19025312360.036
imaginal disc derived wing vein morphogenesisGO:0008586440.036
positive regulation of wnt signaling pathwayGO:0030177250.036
apoptotic processGO:00069151590.036
developmental pigmentationGO:0048066680.035
regulation of catabolic processGO:00098941700.035
regulation of ras protein signal transductionGO:0046578930.035
mitotic g2 dna damage checkpointGO:0007095690.035
cellular protein catabolic processGO:0044257830.035
regulation of protein metabolic processGO:00512462560.035
adult behaviorGO:00305341370.034
signal transduction downstream of smoothenedGO:000722750.034
regulation of apoptotic processGO:00429811300.034
wnt signaling pathwayGO:0016055980.034
deathGO:00162652840.033
protein transportGO:00150311550.033
morphogenesis of an epitheliumGO:00020092760.032
wing disc dorsal ventral pattern formationGO:0048190470.032
intraciliary transportGO:004207380.031
embryonic development via the syncytial blastodermGO:00017001480.031
programmed cell deathGO:00125012570.030
limb developmentGO:006017310.030
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.030
negative regulation of cell cycleGO:00457861160.030
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.030
cell cycle g1 s phase transitionGO:0044843310.029
positive regulation of signalingGO:00230562430.029
response to organonitrogen compoundGO:0010243750.029
organonitrogen compound metabolic processGO:19015643180.029
positive regulation of phosphorylationGO:0042327870.029
regulation of phosphorus metabolic processGO:00511742100.029
macromolecular complex assemblyGO:00650032560.029
anatomical structure homeostasisGO:0060249970.029
response to nutrient levelsGO:00316671140.029
defense responseGO:00069523000.029
eye photoreceptor cell differentiationGO:00017541450.028
phagocytosisGO:00069092150.028
pigmentationGO:0043473750.028
regulation of growthGO:00400082330.028
protein catabolic processGO:00301631010.028
negative regulation of cellular protein metabolic processGO:0032269850.028
vesicle localizationGO:0051648550.028
single organism catabolic processGO:00447122280.027
regulation of proteolysisGO:0030162870.027
regulation of microtubule based processGO:0032886490.027
reproductive structure developmentGO:0048608740.027
protein targeting to nucleusGO:0044744510.027
membrane organizationGO:00610241120.026
retina development in camera type eyeGO:006004140.026
negative regulation of gene expressionGO:00106293870.026
regulation of cellular protein catabolic processGO:1903362440.026
amine metabolic processGO:0009308120.026
cell deathGO:00082192790.025
regulation of protein catabolic processGO:0042176550.025
atp dependent chromatin remodelingGO:0043044220.025
regulation of cytoskeleton organizationGO:0051493890.025
posttranscriptional gene silencingGO:0016441460.024
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.024
spindle localizationGO:0051653220.024
asymmetric cell divisionGO:0008356370.024
peptidyl threonine phosphorylationGO:001810720.024
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.024
positive regulation of phosphorus metabolic processGO:00105621390.024
regulation of phosphate metabolic processGO:00192202100.024
establishment of cell polarityGO:0030010400.023
localization of cellGO:00516742570.023
regulation of cell morphogenesisGO:00226041630.023
notch signaling pathwayGO:00072191200.023
renal system developmentGO:0072001720.023
response to other organismGO:00517072930.023
vesicle mediated transportGO:00161923810.023
negative regulation of cell deathGO:0060548810.023
neural precursor cell proliferationGO:0061351750.023
response to organic cyclic compoundGO:0014070890.023
reproductive system developmentGO:0061458740.023
cuticle pattern formationGO:0035017270.022
small molecule metabolic processGO:00442813050.022
dorsal ventral pattern formationGO:00099531330.022
heart developmentGO:0007507820.022
dna templated transcription elongationGO:0006354180.022
response to organic substanceGO:00100332840.022
regulation of viral genome replicationGO:004506940.022
catabolic processGO:00090564090.022
positive regulation of proteolysisGO:0045862520.022
centrosome organizationGO:00512971630.021
morphogenesis of a branching epitheliumGO:0061138450.021
chaeta developmentGO:0022416970.021
connective tissue developmentGO:006144830.021
mesenchymal cell differentiationGO:004876210.021
nuclear importGO:0051170510.021
peptide metabolic processGO:0006518800.020
sensory organ morphogenesisGO:00905962600.020
ras protein signal transductionGO:0007265880.020
synaptic transmissionGO:00072682880.020
sister chromatid segregationGO:0000819920.020
central nervous system neuron differentiationGO:002195380.020
compound eye pigmentationGO:0048072170.020
regulation of compound eye photoreceptor developmentGO:0045314120.020
establishment of protein localizationGO:00451841630.020
digestive system developmentGO:00551231490.020
dna damage checkpointGO:0000077780.019
establishment of vesicle localizationGO:0051650510.019
male gamete generationGO:00482322010.019
neuroblast differentiationGO:0014016290.019
wing disc pattern formationGO:0035222660.019
protein targeting to lysosomeGO:000662250.019
regulation of proteasomal protein catabolic processGO:0061136390.019
regulation of intracellular protein transportGO:0033157460.019
regulation of neuroblast proliferationGO:1902692340.018
cellular response to endogenous stimulusGO:0071495800.018
regulation of localizationGO:00328792750.018
growthGO:00400073590.018
blood circulationGO:0008015260.018
carboxylic acid metabolic processGO:0019752920.018
developmental programmed cell deathGO:00106231380.018
gland morphogenesisGO:00226121450.018
cellular macromolecule localizationGO:00707272200.017
camera type eye developmentGO:004301040.017
establishment or maintenance of cell polarityGO:00071631670.017
taxisGO:00423303040.017
regulation of hemocyte proliferationGO:0035206370.017
response to oxygen containing compoundGO:19017002000.017
stem cell proliferationGO:0072089880.017
cardiac cell fate commitmentGO:0060911170.016
mrna processingGO:00063971040.016
muscle structure developmentGO:00610612240.016
compound eye photoreceptor developmentGO:0042051780.016
regulation of cellular component biogenesisGO:00440872010.016
cellular macromolecule catabolic processGO:00442651360.016
establishment of planar polarityGO:0001736870.016
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.016
response to radiationGO:00093141550.016
intracellular protein transportGO:00068861040.016
cytoplasmic transportGO:00164821300.016
regulation of sister chromatid segregationGO:0033045280.016
multicellular organism growthGO:0035264460.016
response to biotic stimulusGO:00096072940.016
mapk cascadeGO:00001651070.016
ion transportGO:00068111450.016
regulation of heart morphogenesisGO:200082630.016
negative regulation of cell proliferationGO:0008285690.015
negative regulation of molecular functionGO:0044092510.015
regulation of catalytic activityGO:00507901850.015
signal transduction by phosphorylationGO:00230141070.015
negative regulation of protein metabolic processGO:0051248850.015
negative regulation of organelle organizationGO:0010639560.015
positive regulation of cellular amine metabolic processGO:003324000.015
positive regulation of neurogenesisGO:0050769410.015
gland developmentGO:00487321910.015
regulation of actin filament based processGO:0032970420.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
regulation of microtubule depolymerizationGO:0031114240.015
regulation of eye photoreceptor cell developmentGO:0042478130.015
nucleocytoplasmic transportGO:0006913720.014
dorsal ventral pattern formation imaginal discGO:0007450510.014
positive regulation of cellular component biogenesisGO:0044089800.014
positive regulation of protein phosphorylationGO:0001934340.014
regulation of cell cycle g1 s phase transitionGO:1902806230.014
head developmentGO:00603221350.014
morphogenesis of a branching structureGO:0001763450.014
negative regulation of microtubule depolymerizationGO:0007026210.014
regulation of neuron projection developmentGO:0010975690.013
establishment of protein localization to organelleGO:0072594620.013
positive regulation of intracellular signal transductionGO:19025331160.013
regulation of notch signaling pathwayGO:00085931000.013
positive regulation of catalytic activityGO:00430851180.013
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573610.013
sex differentiationGO:0007548810.013
axis specificationGO:00097981670.013
positive regulation of cell communicationGO:00106472500.013
adult locomotory behaviorGO:0008344760.013
regulation of transferase activityGO:0051338580.013
mrna metabolic processGO:00160711240.013
organic substance catabolic processGO:19015753080.013
positive regulation of cell deathGO:0010942690.013
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.013
multi organism behaviorGO:00517051750.013
multi multicellular organism processGO:00447061230.013
regulation of establishment of protein localizationGO:0070201610.012
regulation of smoothened signaling pathwayGO:0008589280.012
positive regulation of multicellular organismal processGO:00512401430.012
positive regulation of protein transportGO:0051222370.012
photoreceptor cell differentiationGO:00465301700.012
dna integrity checkpointGO:0031570810.012
cellular homeostasisGO:0019725800.012
somatic stem cell maintenanceGO:0035019140.012
spermatogenesisGO:00072832000.012
protein polymerizationGO:0051258420.012
compound eye photoreceptor cell differentiationGO:00017511400.012
mitotic nuclear divisionGO:00070672130.012
organic substance transportGO:00717022570.012
negative regulation of neuroblast proliferationGO:0007406270.012
locomotory behaviorGO:00076261760.012
proteolysis involved in cellular protein catabolic processGO:0051603830.011
maintenance of gastrointestinal epitheliumGO:003027730.011
tissue deathGO:00162711020.011
canonical wnt signaling pathway involved in heart developmentGO:006131630.011
small gtpase mediated signal transductionGO:0007264880.011
heart morphogenesisGO:0003007320.011
protein targetingGO:0006605640.011
regulation of reproductive processGO:2000241540.011
organelle inheritanceGO:004830820.011
regulation of phosphatase activityGO:001092130.011
protein processingGO:0016485680.011
centrosome duplicationGO:00512981210.011
chaeta morphogenesisGO:0008407420.011
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.011
determination of adult lifespanGO:00083401370.010
ameboidal type cell migrationGO:00016671510.010
regulation of nucleocytoplasmic transportGO:0046822350.010
positive regulation of mitotic cell cycleGO:0045931340.010
imaginal disc derived leg segmentationGO:0036011260.010
organelle assemblyGO:00709251980.010
camera type eye morphogenesisGO:004859320.010
protein import into nucleusGO:0006606510.010
positive regulation of phosphate metabolic processGO:00459371390.010
negative regulation of nervous system developmentGO:0051961920.010
multicellular organismal agingGO:00102591400.010
regulation of molecular functionGO:00650092170.010
cellular catabolic processGO:00442483720.010
negative regulation of multicellular organismal processGO:00512411420.010
regulation of g2 m transition of mitotic cell cycleGO:0010389150.010

pygo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
disease of cellular proliferationDOID:1456600.028
organ system cancerDOID:005068600.010
cancerDOID:16200.010