| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.720 | |
| acylglycerol biosynthetic process | GO:0046463 | 2 | 0.682 | |
| positive regulation of gene expression | GO:0010628 | 290 | 0.620 | |
| response to nutrient levels | GO:0031667 | 114 | 0.559 | |
| cellular response to external stimulus | GO:0071496 | 66 | 0.510 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.506 | |
| response to extracellular stimulus | GO:0009991 | 116 | 0.497 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.480 | |
| response to starvation | GO:0042594 | 97 | 0.477 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.449 | |
| translation | GO:0006412 | 69 | 0.400 | Rat |
| positive regulation of insulin receptor signaling pathway | GO:0046628 | 3 | 0.395 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.384 | |
| determination of adult lifespan | GO:0008340 | 137 | 0.370 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.349 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.336 | |
| regulation of response to stress | GO:0080134 | 200 | 0.327 | |
| fatty acid homeostasis | GO:0055089 | 2 | 0.319 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.289 | |
| response to abiotic stimulus | GO:0009628 | 341 | 0.285 | Mouse |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.261 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.257 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.245 | |
| larval development | GO:0002164 | 104 | 0.243 | |
| anion homeostasis | GO:0055081 | 3 | 0.242 | |
| apoptotic process | GO:0006915 | 159 | 0.238 | Mouse |
| tor signaling | GO:0031929 | 32 | 0.233 | |
| homeostatic process | GO:0042592 | 199 | 0.223 | |
| multicellular organismal aging | GO:0010259 | 140 | 0.216 | |
| intracellular signal transduction | GO:0035556 | 300 | 0.211 | |
| aging | GO:0007568 | 143 | 0.201 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 145 | 0.184 | Rat |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.183 | |
| regulation of multicellular organism growth | GO:0040014 | 40 | 0.168 | |
| cellular response to extracellular stimulus | GO:0031668 | 64 | 0.166 | |
| gene silencing by rna | GO:0031047 | 57 | 0.160 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.156 | |
| chromatin modification | GO:0016568 | 147 | 0.154 | |
| secondary metabolite biosynthetic process | GO:0044550 | 24 | 0.152 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.149 | |
| cellular response to starvation | GO:0009267 | 61 | 0.136 | |
| macroautophagy | GO:0016236 | 42 | 0.124 | |
| programmed cell death | GO:0012501 | 257 | 0.122 | Mouse |
| oxoacid metabolic process | GO:0043436 | 103 | 0.122 | |
| response to hypoxia | GO:0001666 | 53 | 0.118 | |
| transmembrane transport | GO:0055085 | 139 | 0.110 | |
| regulation of cellular response to insulin stimulus | GO:1900076 | 17 | 0.107 | |
| autophagy | GO:0006914 | 108 | 0.106 | |
| negative regulation of phosphatidylinositol 3 kinase signaling | GO:0014067 | 4 | 0.106 | |
| lateral inhibition | GO:0046331 | 206 | 0.103 | |
| apoptotic signaling pathway | GO:0097190 | 27 | 0.102 | Mouse |
| regulation of response to external stimulus | GO:0032101 | 115 | 0.099 | |
| regulation of response to extracellular stimulus | GO:0032104 | 18 | 0.099 | |
| innate immune response | GO:0045087 | 144 | 0.097 | |
| cell proliferation | GO:0008283 | 299 | 0.096 | |
| compound eye morphogenesis | GO:0001745 | 249 | 0.094 | |
| neutral lipid biosynthetic process | GO:0046460 | 2 | 0.092 | |
| cellular macromolecule catabolic process | GO:0044265 | 136 | 0.091 | |
| chromatin organization | GO:0006325 | 207 | 0.089 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.089 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.088 | |
| regulation of defense response | GO:0031347 | 102 | 0.088 | |
| oxidation reduction process | GO:0055114 | 123 | 0.088 | |
| gene silencing | GO:0016458 | 138 | 0.086 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.085 | |
| chemical homeostasis | GO:0048878 | 92 | 0.083 | |
| cell cycle phase transition | GO:0044770 | 140 | 0.083 | |
| regulation of cellular component biogenesis | GO:0044087 | 201 | 0.080 | |
| defense response | GO:0006952 | 300 | 0.077 | |
| triglyceride biosynthetic process | GO:0019432 | 2 | 0.077 | |
| positive regulation of lipid catabolic process | GO:0050996 | 1 | 0.077 | |
| posttranscriptional gene silencing | GO:0016441 | 46 | 0.077 | |
| negative regulation of cell cycle process | GO:0010948 | 109 | 0.077 | |
| skeletal muscle adaptation | GO:0043501 | 1 | 0.076 | |
| maintenance of location | GO:0051235 | 73 | 0.072 | |
| striated muscle adaptation | GO:0014888 | 1 | 0.071 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.070 | |
| ion transmembrane transport | GO:0034220 | 122 | 0.069 | |
| positive regulation of developmental process | GO:0051094 | 143 | 0.069 | |
| positive regulation of lipid metabolic process | GO:0045834 | 4 | 0.068 | |
| response to decreased oxygen levels | GO:0036293 | 58 | 0.066 | |
| regulation of dna metabolic process | GO:0051052 | 34 | 0.066 | |
| synaptic transmission | GO:0007268 | 288 | 0.064 | |
| death | GO:0016265 | 284 | 0.064 | Mouse |
| regulation of phosphorylation | GO:0042325 | 147 | 0.060 | |
| cellular catabolic process | GO:0044248 | 372 | 0.060 | |
| response to organic substance | GO:0010033 | 284 | 0.059 | |
| associative learning | GO:0008306 | 65 | 0.058 | |
| posttranscriptional gene silencing by rna | GO:0035194 | 45 | 0.058 | |
| positive regulation of growth | GO:0045927 | 75 | 0.057 | |
| dna metabolic process | GO:0006259 | 227 | 0.056 | |
| catabolic process | GO:0009056 | 409 | 0.056 | |
| learning or memory | GO:0007611 | 141 | 0.056 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.054 | |
| cellular response to oxygen levels | GO:0071453 | 30 | 0.054 | |
| protein phosphorylation | GO:0006468 | 169 | 0.054 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.053 | |
| regulation of cell growth | GO:0001558 | 43 | 0.052 | |
| chromosome organization | GO:0051276 | 360 | 0.051 | |
| metal ion homeostasis | GO:0055065 | 44 | 0.051 | |
| immune system process | GO:0002376 | 347 | 0.050 | Human |
| positive regulation of protein metabolic process | GO:0051247 | 128 | 0.050 | |
| mrna catabolic process | GO:0006402 | 33 | 0.050 | |
| mitotic cell cycle phase transition | GO:0044772 | 138 | 0.049 | |
| nucleobase containing compound catabolic process | GO:0034655 | 165 | 0.049 | |
| lipid localization | GO:0010876 | 54 | 0.049 | |
| regulation of cell cycle phase transition | GO:1901987 | 130 | 0.049 | |
| phosphorylation | GO:0016310 | 294 | 0.048 | |
| regulation of cell proliferation | GO:0042127 | 163 | 0.048 | |
| cellular response to nutrient levels | GO:0031669 | 62 | 0.045 | |
| regulation of cell death | GO:0010941 | 173 | 0.044 | |
| response to oxygen levels | GO:0070482 | 59 | 0.043 | |
| cellular response to sterol depletion | GO:0071501 | 3 | 0.043 | |
| cellular response to dna damage stimulus | GO:0006974 | 223 | 0.043 | |
| ion transport | GO:0006811 | 145 | 0.043 | |
| response to temperature stimulus | GO:0009266 | 106 | 0.041 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.041 | |
| regulation of immune system process | GO:0002682 | 176 | 0.041 | |
| dendrite morphogenesis | GO:0048813 | 199 | 0.041 | |
| mitotic dna integrity checkpoint | GO:0044774 | 75 | 0.040 | |
| regulation of developmental growth | GO:0048638 | 174 | 0.039 | |
| atp metabolic process | GO:0046034 | 49 | 0.039 | |
| protein catabolic process | GO:0030163 | 101 | 0.038 | |
| eye morphogenesis | GO:0048592 | 260 | 0.037 | |
| developmental pigmentation | GO:0048066 | 68 | 0.037 | |
| forebrain development | GO:0030900 | 2 | 0.037 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 103 | 0.036 | |
| regulation of insulin receptor signaling pathway | GO:0046626 | 17 | 0.036 | |
| growth | GO:0040007 | 359 | 0.036 | |
| macromolecular complex assembly | GO:0065003 | 256 | 0.036 | |
| brain development | GO:0007420 | 120 | 0.036 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 38 | 0.036 | |
| regulation of mitotic cell cycle | GO:0007346 | 190 | 0.035 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.035 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.034 | |
| negative regulation of autophagy | GO:0010507 | 16 | 0.034 | |
| positive regulation of lipid biosynthetic process | GO:0046889 | 3 | 0.034 | |
| organic cyclic compound catabolic process | GO:1901361 | 168 | 0.033 | |
| learning | GO:0007612 | 75 | 0.033 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.032 | Rat |
| cellular carbohydrate metabolic process | GO:0044262 | 22 | 0.032 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 3 | 0.032 | |
| regulation of response to nutrient levels | GO:0032107 | 18 | 0.031 | |
| establishment or maintenance of cell polarity | GO:0007163 | 167 | 0.031 | |
| acyl coa metabolic process | GO:0006637 | 3 | 0.031 | |
| gene silencing by mirna | GO:0035195 | 22 | 0.030 | |
| mrna metabolic process | GO:0016071 | 124 | 0.030 | |
| cellular protein modification process | GO:0006464 | 438 | 0.030 | |
| rna catabolic process | GO:0006401 | 37 | 0.030 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.029 | |
| mitotic dna damage checkpoint | GO:0044773 | 74 | 0.029 | |
| mitotic cell cycle checkpoint | GO:0007093 | 88 | 0.029 | |
| regulation of autophagy | GO:0010506 | 62 | 0.029 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.028 | |
| positive regulation of phosphorylation | GO:0042327 | 87 | 0.028 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 165 | 0.028 | |
| regulation of apoptotic process | GO:0042981 | 130 | 0.027 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.027 | |
| regulation of response to oxidative stress | GO:1902882 | 4 | 0.027 | |
| response to endoplasmic reticulum stress | GO:0034976 | 28 | 0.027 | |
| regulation of cellular carbohydrate metabolic process | GO:0010675 | 7 | 0.027 | |
| positive regulation of organelle organization | GO:0010638 | 65 | 0.027 | |
| spindle organization | GO:0007051 | 253 | 0.027 | |
| regulation of gene expression epigenetic | GO:0040029 | 128 | 0.027 | |
| cellular response to chemical stimulus | GO:0070887 | 199 | 0.026 | Human |
| atp catabolic process | GO:0006200 | 38 | 0.026 | |
| activation of protein kinase activity | GO:0032147 | 12 | 0.026 | |
| positive regulation of cell size | GO:0045793 | 21 | 0.026 | |
| regulation of transport | GO:0051049 | 181 | 0.026 | |
| heterocycle catabolic process | GO:0046700 | 166 | 0.026 | |
| regulation of macroautophagy | GO:0016241 | 15 | 0.026 | |
| response to heat | GO:0009408 | 63 | 0.026 | |
| dendrite development | GO:0016358 | 204 | 0.025 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 103 | 0.025 | |
| regulation of cell size | GO:0008361 | 63 | 0.025 | |
| positive regulation of developmental growth | GO:0048639 | 62 | 0.025 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.025 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.024 | |
| aromatic compound catabolic process | GO:0019439 | 166 | 0.024 | |
| regulation of organelle organization | GO:0033043 | 196 | 0.024 | |
| stem cell differentiation | GO:0048863 | 117 | 0.024 | |
| protein complex biogenesis | GO:0070271 | 201 | 0.024 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 109 | 0.024 | |
| monocarboxylic acid metabolic process | GO:0032787 | 29 | 0.023 | |
| negative regulation of neurogenesis | GO:0050768 | 53 | 0.023 | |
| imaginal disc growth | GO:0007446 | 37 | 0.023 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.023 | |
| negative regulation of cellular response to oxidative stress | GO:1900408 | 1 | 0.022 | |
| response to organic cyclic compound | GO:0014070 | 89 | 0.022 | |
| carbohydrate metabolic process | GO:0005975 | 82 | 0.022 | |
| positive regulation of multicellular organism growth | GO:0040018 | 21 | 0.022 | |
| response to light stimulus | GO:0009416 | 124 | 0.022 | |
| regulation of translation | GO:0006417 | 56 | 0.022 | Rat |
| response to hexose | GO:0009746 | 3 | 0.022 | |
| jak stat cascade | GO:0007259 | 49 | 0.022 | |
| response to monosaccharide | GO:0034284 | 4 | 0.021 | |
| organic acid metabolic process | GO:0006082 | 103 | 0.021 | |
| compound eye development | GO:0048749 | 307 | 0.021 | |
| central nervous system development | GO:0007417 | 201 | 0.021 | |
| cell cell signaling involved in cell fate commitment | GO:0045168 | 210 | 0.021 | |
| cognition | GO:0050890 | 141 | 0.021 | |
| endocytosis | GO:0006897 | 310 | 0.021 | |
| cellular response to peptide | GO:1901653 | 28 | 0.020 | |
| negative regulation of response to oxidative stress | GO:1902883 | 1 | 0.020 | |
| regulation of epithelial cell proliferation | GO:0050678 | 4 | 0.020 | |
| taxis | GO:0042330 | 304 | 0.020 | |
| dna integrity checkpoint | GO:0031570 | 81 | 0.020 | |
| molting cycle chitin based cuticle | GO:0007591 | 56 | 0.020 | |
| multi organism reproductive behavior | GO:0044705 | 121 | 0.020 | |
| peptidyl threonine phosphorylation | GO:0018107 | 2 | 0.020 | |
| adult behavior | GO:0030534 | 137 | 0.020 | |
| chromosome segregation | GO:0007059 | 157 | 0.020 | |
| lipid homeostasis | GO:0055088 | 33 | 0.019 | |
| telomere organization | GO:0032200 | 21 | 0.019 | |
| cellular ketone metabolic process | GO:0042180 | 24 | 0.019 | |
| meiotic chromosome segregation | GO:0045132 | 59 | 0.019 | |
| regulation of cellular catabolic process | GO:0031329 | 157 | 0.019 | |
| single organism behavior | GO:0044708 | 391 | 0.019 | |
| microtubule based transport | GO:0010970 | 42 | 0.019 | |
| telomere maintenance | GO:0000723 | 21 | 0.019 | |
| neuron projection guidance | GO:0097485 | 241 | 0.018 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 57 | 0.018 | |
| rna processing | GO:0006396 | 147 | 0.018 | |
| positive regulation of multicellular organismal process | GO:0051240 | 143 | 0.018 | |
| regulation of phosphate metabolic process | GO:0019220 | 210 | 0.018 | |
| heterochromatin organization | GO:0070828 | 25 | 0.018 | |
| histone modification | GO:0016570 | 106 | 0.018 | |
| regulation of growth | GO:0040008 | 233 | 0.017 | |
| positive regulation of kinase activity | GO:0033674 | 25 | 0.017 | |
| eye development | GO:0001654 | 323 | 0.017 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.017 | |
| germ line stem cell maintenance | GO:0030718 | 50 | 0.017 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 130 | 0.017 | |
| regulation of programmed cell death | GO:0043067 | 152 | 0.017 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 83 | 0.017 | |
| cell death | GO:0008219 | 279 | 0.016 | Mouse |
| regulation of imaginal disc growth | GO:0045570 | 26 | 0.016 | |
| vesicle mediated transport | GO:0016192 | 381 | 0.016 | |
| chemotaxis | GO:0006935 | 249 | 0.016 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 139 | 0.016 | |
| regulation of tor signaling | GO:0032006 | 21 | 0.016 | |
| axon cargo transport | GO:0008088 | 29 | 0.016 | |
| olfactory learning | GO:0008355 | 56 | 0.016 | |
| regulation of protein phosphorylation | GO:0001932 | 64 | 0.015 | |
| lipid metabolic process | GO:0006629 | 121 | 0.015 | |
| regulation of mitochondrial fusion | GO:0010635 | 5 | 0.015 | |
| regulation of cellular response to hypoxia | GO:1900037 | 3 | 0.015 | |
| regulation of ion transport | GO:0043269 | 39 | 0.015 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 240 | 0.015 | |
| metal ion transport | GO:0030001 | 74 | 0.015 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.015 | |
| regulation of mitochondrial fission | GO:0090140 | 7 | 0.014 | |
| regulation of nervous system development | GO:0051960 | 248 | 0.014 | |
| autophagic vacuole fusion | GO:0000046 | 15 | 0.014 | |
| negative regulation of transcription dna templated | GO:0045892 | 237 | 0.014 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.014 | |
| regulation of membrane potential | GO:0042391 | 35 | 0.014 | |
| primary spermatocyte growth | GO:0007285 | 5 | 0.014 | |
| reproductive behavior | GO:0019098 | 122 | 0.014 | |
| organelle membrane fusion | GO:0090174 | 16 | 0.014 | |
| negative regulation of tor signaling | GO:0032007 | 5 | 0.014 | |
| cellular response to organic substance | GO:0071310 | 132 | 0.014 | |
| histone h4 k16 acetylation | GO:0043984 | 4 | 0.014 | |
| response to oxidative stress | GO:0006979 | 86 | 0.013 | |
| regulation of synaptic transmission | GO:0050804 | 69 | 0.013 | |
| positive regulation of protein phosphorylation | GO:0001934 | 34 | 0.013 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 119 | 0.013 | |
| single organism membrane budding | GO:1902591 | 2 | 0.013 | |
| response to uv | GO:0009411 | 24 | 0.013 | |
| response to oxygen containing compound | GO:1901700 | 200 | 0.013 | |
| sex differentiation | GO:0007548 | 81 | 0.013 | |
| covalent chromatin modification | GO:0016569 | 106 | 0.013 | |
| cytoskeleton dependent intracellular transport | GO:0030705 | 44 | 0.013 | |
| g2 dna damage checkpoint | GO:0031572 | 69 | 0.013 | |
| photoreceptor cell differentiation | GO:0046530 | 170 | 0.013 | |
| endomembrane system organization | GO:0010256 | 119 | 0.013 | |
| dna damage checkpoint | GO:0000077 | 78 | 0.012 | |
| ncrna metabolic process | GO:0034660 | 43 | 0.012 | |
| long term memory | GO:0007616 | 62 | 0.012 | |
| female meiotic division | GO:0007143 | 70 | 0.012 | |
| response to peptide | GO:1901652 | 29 | 0.012 | |
| regulation of cellular amine metabolic process | GO:0033238 | 3 | 0.012 | |
| somatic muscle development | GO:0007525 | 66 | 0.012 | |
| insulin receptor signaling pathway | GO:0008286 | 25 | 0.012 | |
| sperm mitochondrion organization | GO:0030382 | 7 | 0.012 | |
| regulation of phosphatase activity | GO:0010921 | 3 | 0.012 | |
| lipid storage | GO:0019915 | 38 | 0.012 | |
| negative regulation of g2 m transition of mitotic cell cycle | GO:0010972 | 8 | 0.012 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.012 | |
| regulation of cellular response to oxidative stress | GO:1900407 | 4 | 0.011 | |
| response to peptide hormone | GO:0043434 | 29 | 0.011 | |
| regulation of jnk cascade | GO:0046328 | 40 | 0.011 | |
| positive regulation of immune system process | GO:0002684 | 68 | 0.011 | |
| single organism membrane organization | GO:0044802 | 93 | 0.011 | |
| negative regulation of epithelial cell proliferation | GO:0050680 | 4 | 0.011 | |
| negative regulation of nervous system development | GO:0051961 | 92 | 0.011 | |
| regulation of photoreceptor cell differentiation | GO:0046532 | 34 | 0.011 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 23 | 0.011 | |
| locomotory behavior | GO:0007626 | 176 | 0.011 | |
| regulation of cellular response to stress | GO:0080135 | 89 | 0.011 | |
| regulation of neurogenesis | GO:0050767 | 158 | 0.011 | |
| regulation of cell fate commitment | GO:0010453 | 29 | 0.011 | |
| response to glucose | GO:0009749 | 2 | 0.011 | |
| regulation of cell junction assembly | GO:1901888 | 2 | 0.011 | |
| cation transport | GO:0006812 | 110 | 0.011 | |
| protein localization | GO:0008104 | 284 | 0.011 | |
| negative regulation of apoptotic process | GO:0043066 | 63 | 0.011 | |
| negative regulation of growth of symbiont involved in interaction with host | GO:0044146 | 9 | 0.010 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 16 | 0.010 | |
| response to metal ion | GO:0010038 | 23 | 0.010 | |
| cellular response to hormone stimulus | GO:0032870 | 44 | 0.010 | |
| negative regulation of cell proliferation | GO:0008285 | 69 | 0.010 | |
| hindbrain development | GO:0030902 | 2 | 0.010 | |
