Drosophila melanogaster

60 known processes

ppk (Dmel_CG3478)

pickpocket

(Aliases: CG3478,BG:DS06238.1,pkt,Dmel\CG3478,PPK,mdNaC1,dmdNaC1,dmdNaCl,PPK1,ppk1)

ppk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval behaviorGO:0030537420.951
single organism behaviorGO:00447083910.786
circadian behaviorGO:0048512760.697
regulation of behaviorGO:0050795750.608
multi organism reproductive behaviorGO:00447051210.598
Fly
aggressive behaviorGO:0002118630.521
Fly
circadian rhythmGO:00076231050.501
matingGO:00076181200.481
Fly
rhythmic processGO:00485111060.475
response to temperature stimulusGO:00092661060.451
response to abiotic stimulusGO:00096283410.438
locomotory behaviorGO:00076261760.401
sensory perception of mechanical stimulusGO:0050954720.369
detection of mechanical stimulus involved in sensory perception of painGO:005096620.359
feeding behaviorGO:0007631500.349
response to radiationGO:00093141550.329
response to light stimulusGO:00094161240.311
larval locomotory behaviorGO:0008345270.308
synaptic transmissionGO:00072682880.296
Fly
mating behaviorGO:00076171060.251
Fly
multi organism behaviorGO:00517051750.237
Fly
multicellular organismal reproductive behaviorGO:00330571100.219
Fly
negative regulation of response to stimulusGO:00485852580.197
inter male aggressive behaviorGO:0002121600.167
Fly
response to organic substanceGO:00100332840.166
Fly
cellular response to abiotic stimulusGO:0071214580.161
Fly
larval feeding behaviorGO:0030536150.155
courtship behaviorGO:0007619680.147
Fly
male courtship behaviorGO:0008049630.139
Fly
rhythmic behaviorGO:0007622760.133
cell migrationGO:00164772380.131
Rat
cellular response to organonitrogen compoundGO:0071417360.130
regulation of anatomical structure sizeGO:00900661630.114
glycerolipid catabolic processGO:004650330.112
positive regulation of cell communicationGO:00106472500.111
cellular response to insulin stimulusGO:0032869280.110
multi multicellular organism processGO:00447061230.108
Fly
cell motilityGO:00488702510.101
Rat
localization of cellGO:00516742570.100
Rat
agingGO:00075681430.100
positive regulation of response to stimulusGO:00485843230.098
male mating behaviorGO:0060179700.097
Fly
reproductive behaviorGO:00190981220.095
Fly
negative regulation of developmental processGO:00510932010.093
sensory perception of salty tasteGO:005091430.090
Fly
response to insulinGO:0032868290.089
taxisGO:00423303040.089
determination of adult lifespanGO:00083401370.089
mechanosensory behaviorGO:0007638120.087
detection of stimulus involved in sensory perceptionGO:0050906920.085
positive regulation of multicellular organismal processGO:00512401430.080
growthGO:00400073590.079
chemical homeostasisGO:0048878920.076
Human
developmental growthGO:00485892800.076
cellular response to organic substanceGO:00713101320.075
embryonic morphogenesisGO:00485982060.074
intracellular signal transductionGO:00355563000.074
negative regulation of behaviorGO:004852180.070
cellular response to nitrogen compoundGO:1901699510.070
response to mechanical stimulusGO:0009612280.069
response to oxygen containing compoundGO:19017002000.069
Fly
multicellular organismal agingGO:00102591400.066
sensory perception of painGO:001923340.066
response to foodGO:003209430.062
locomotor rhythmGO:0045475560.061
positive regulation of signalingGO:00230562430.060
intraspecies interaction between organismsGO:005170340.059
negative regulation of signalingGO:00230572190.058
regulation of growthGO:00400082330.056
homeostatic processGO:00425921990.055
Human
response to painGO:004826530.055
cellular response to peptide hormone stimulusGO:0071375280.054
positive regulation of growthGO:0045927750.053
single organism catabolic processGO:00447122280.053
organic substance catabolic processGO:19015753080.052
regulation of developmental growthGO:00486381740.052
response to woundingGO:0009611940.051
Rat
response to peptide hormoneGO:0043434290.051
small molecule metabolic processGO:00442813050.051
cellular response to oxygen containing compoundGO:1901701790.050
Fly
cellular response to endogenous stimulusGO:0071495800.049
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.048
social behaviorGO:003517640.048
regulation of synapse structure and activityGO:00508031280.048
Fly
response to nitrogen compoundGO:1901698900.047
organonitrogen compound metabolic processGO:19015643180.046
detection of stimulusGO:00516061560.045
regulation of localizationGO:00328792750.045
Rat
kidney developmentGO:000182230.044
regulation of circadian rhythmGO:0042752490.044
enzyme linked receptor protein signaling pathwayGO:00071671790.044
wound healingGO:0042060750.043
Rat
regulation of cell developmentGO:00602842150.042
cellular response to peptideGO:1901653280.041
cilium morphogenesisGO:0060271390.041
cell proliferationGO:00082832990.041
neurological system processGO:00508773580.040
cellular protein modification processGO:00064644380.039
positive regulation of developmental growthGO:0048639620.039
telencephalon developmentGO:002153720.039
regulation of cell morphogenesisGO:00226041630.038
g protein coupled receptor signaling pathwayGO:00071861360.038
response to nutrient levelsGO:00316671140.038
cation homeostasisGO:0055080510.038
Human
female mating behaviorGO:0060180300.037
regulation of tube sizeGO:0035150460.037
regulation of dendrite developmentGO:0050773370.037
negative regulation of cellular component organizationGO:00511291080.036
response to endogenous stimulusGO:00097191190.036
tissue morphogenesisGO:00487292970.036
Rat
digestive tract developmentGO:00485651490.036
organic acid metabolic processGO:00060821030.036
response to inorganic substanceGO:0010035440.035
Fly
morphogenesis of an epitheliumGO:00020092760.035
Rat
protein modification processGO:00362114380.035
detection of abiotic stimulusGO:0009582660.034
regulation of camp biosynthetic processGO:0030817120.034
protein phosphorylationGO:00064681690.034
epibolyGO:009050420.033
Rat
response to acid chemicalGO:0001101250.033
Fly
negative regulation of nervous system developmentGO:0051961920.033
negative regulation of developmental growthGO:0048640640.033
regionalizationGO:00030024160.032
olfactory learningGO:0008355560.032
forebrain developmentGO:003090020.032
spermatogenesisGO:00072832000.032
oxoacid metabolic processGO:00434361030.031
water homeostasisGO:003010430.031
Human
epiboly involved in wound healingGO:009050520.031
Rat
negative regulation of cell communicationGO:00106482230.030
response to extracellular stimulusGO:00099911160.030
chemosensory behaviorGO:00076351060.030
cognitionGO:00508901410.029
regulation of multicellular organismal developmentGO:20000264140.029
regulation of synaptic transmissionGO:0050804690.029
Fly
positive regulation of phosphate metabolic processGO:00459371390.029
olfactory behaviorGO:0042048970.028
regulation of cell sizeGO:0008361630.028
regulation of nervous system developmentGO:00519602480.028
thermotaxisGO:0043052160.028
cuticle developmentGO:0042335860.028
convergent extensionGO:006002620.027
circulatory system processGO:0003013370.027
sensory perceptionGO:00076001960.027
anatomical structure homeostasisGO:0060249970.027
cellular response to chemical stimulusGO:00708871990.027
Fly
camera type eye developmentGO:004301040.026
developmental maturationGO:00217001720.026
salt aversionGO:003519930.025
Fly
actin filament based processGO:00300292200.025
epithelial cell differentiationGO:00308553220.025
columnar cuboidal epithelial cell developmentGO:00020662490.025
regulation of dendrite morphogenesisGO:0048814280.025
negative regulation of multicellular organismal processGO:00512411420.024
regulation of cellular protein metabolic processGO:00322682430.024
ovarian follicle cell developmentGO:00307072480.024
mitotic nuclear divisionGO:00070672130.024
sleepGO:0030431490.024
positive regulation of biosynthetic processGO:00098913160.023
positive regulation of cellular biosynthetic processGO:00313283160.023
spinal cord developmentGO:002151010.023
regulation of locomotionGO:0040012420.023
stem cell differentiationGO:00488631170.023
cellular amino acid metabolic processGO:0006520610.023
sensory organ morphogenesisGO:00905962600.022
monovalent inorganic cation transportGO:0015672400.022
regulation of feeding behaviorGO:0060259160.022
regulation of anatomical structure morphogenesisGO:00226032420.021
negative regulation of growthGO:0045926840.021
regulation of membrane potentialGO:0042391350.021
cellular response to hormone stimulusGO:0032870440.021
appendage developmentGO:00487364010.021
positive regulation of developmental processGO:00510941430.021
post embryonic appendage morphogenesisGO:00351203850.020
negative regulation of signal transductionGO:00099682060.020
catabolic processGO:00090564090.020
cell projection assemblyGO:0030031940.020
carboxylic acid metabolic processGO:0019752920.020
digestive tract morphogenesisGO:00485461270.020
phototaxisGO:0042331210.020
sodium ion transportGO:0006814220.019
regulation of system processGO:0044057360.019
respiratory system developmentGO:00605412130.019
Fly
central nervous system developmentGO:00074172010.019
gastrulationGO:0007369700.019
actin cytoskeleton organizationGO:00300362060.019
epithelial cell developmentGO:00020642740.019
cell recognitionGO:00080371020.019
cellular lipid catabolic processGO:0044242160.019
learningGO:0007612750.019
phosphorylationGO:00163102940.019
cellular amine metabolic processGO:0044106120.019
biological adhesionGO:00226101380.018
positive regulation of signal transductionGO:00099672230.018
eye developmentGO:00016543230.018
chaeta developmentGO:0022416970.018
negative regulation of cellular metabolic processGO:00313243820.018
regulation of phosphorylationGO:00423251470.018
regulation of protein metabolic processGO:00512462560.018
sensory perception of soundGO:0007605560.018
positive regulation of intracellular signal transductionGO:19025331160.017
detection of mechanical stimulusGO:005098260.017
dendrite developmentGO:00163582040.017
nucleoside phosphate metabolic processGO:00067531620.017
epithelial tube morphogenesisGO:0060562880.017
regulation of protein modification processGO:00313991120.017
vesicle mediated transportGO:00161923810.017
regulation of programmed cell deathGO:00430671520.017
appendage morphogenesisGO:00351073970.017
camera type eye morphogenesisGO:004859320.017
photoreceptor cell axon guidanceGO:0072499230.017
regulation of cell cycleGO:00517262910.017
regulation of cellular component sizeGO:0032535980.016
neuropeptide signaling pathwayGO:0007218450.016
response to ethanolGO:0045471590.016
regulation of intracellular signal transductionGO:19025312360.016
response to oxygen levelsGO:0070482590.016
Rat
regulation of blood circulationGO:1903522210.016
response to organophosphorusGO:004668320.016
notch signaling pathwayGO:00072191200.016
memoryGO:0007613940.016
cyclic purine nucleotide metabolic processGO:0052652250.016
ion transmembrane transportGO:00342201220.016
response to alcoholGO:0097305950.015
ras protein signal transductionGO:0007265880.015
nuclear divisionGO:00002803320.015
metal ion transportGO:0030001740.015
urogenital system developmentGO:0001655720.015
negative regulation of phosphorylationGO:0042326350.015
digestive system developmentGO:00551231490.015
steroid catabolic processGO:000670610.015
positive regulation of phosphorus metabolic processGO:00105621390.015
insulin receptor signaling pathwayGO:0008286250.015
negative regulation of cellular protein metabolic processGO:0032269850.015
cellular response to carbohydrate stimulusGO:007132240.015
behavioral response to painGO:004826630.014
antennal morphogenesisGO:0048800140.014
sensory perception of touchGO:0050975110.014
Fly
response to alkaloidGO:0043279260.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.014
apoptotic processGO:00069151590.014
compound eye photoreceptor cell differentiationGO:00017511400.014
dendrite morphogenesisGO:00488131990.014
nucleobase containing small molecule metabolic processGO:00550861740.014
adult locomotory behaviorGO:0008344760.014
stem cell proliferationGO:0072089880.014
negative regulation of cell differentiationGO:00455961430.014
organelle fissionGO:00482853400.014
purine ribonucleotide metabolic processGO:00091501450.014
purine containing compound metabolic processGO:00725211550.014
protein localizationGO:00081042840.014
regulation of camp metabolic processGO:0030814120.013
imaginal disc derived appendage developmentGO:00487373990.013
protein processingGO:0016485680.013
organelle assemblyGO:00709251980.013
tube morphogenesisGO:00352391910.013
associative learningGO:0008306650.013
chitin based cuticle developmentGO:0040003490.013
regulation of response to extracellular stimulusGO:0032104180.013
neuromuscular junction developmentGO:00075281490.013
cellular protein localizationGO:00346131600.013
eggshell formationGO:00307031050.013
cellular ketone metabolic processGO:0042180240.013
response to organonitrogen compoundGO:0010243750.013
regulation of notch signaling pathwayGO:00085931000.013
response to heatGO:0009408630.013
programmed cell deathGO:00125012570.013
organophosphate catabolic processGO:00464341120.013
actin filament based movementGO:0030048260.012
phagocytosisGO:00069092150.012
response to hypoxiaGO:0001666530.012
Rat
purine nucleotide metabolic processGO:00061631460.012
single organism biosynthetic processGO:00447112060.012
cilium assemblyGO:0042384380.012
photoreceptor cell differentiationGO:00465301700.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
response to decreased oxygen levelsGO:0036293580.012
Rat
regulation of phosphorus metabolic processGO:00511742100.012
regulation of transportGO:00510491810.012
Rat
organic substance transportGO:00717022570.012
visual learningGO:000854240.012
ribonucleoside metabolic processGO:00091191270.012
transmembrane transportGO:00550851390.012
response to other organismGO:00517072930.012
organic cyclic compound catabolic processGO:19013611680.012
lipid catabolic processGO:0016042210.012
regulation of cell differentiationGO:00455953020.012
dorsal ventral pattern formationGO:00099531330.012
compound eye morphogenesisGO:00017452490.012
hindbrain developmentGO:003090220.012
positive regulation of nucleobase containing compound metabolic processGO:00459353320.012
ribose phosphate metabolic processGO:00196931450.012
blood circulationGO:0008015260.012
protein maturationGO:0051604710.012
regulation of cellular component movementGO:0051270420.012
regulation of neuron projection developmentGO:0010975690.012
mesenchymal cell developmentGO:001403110.012
axon developmentGO:00615642970.012
regulation of cell substrate adhesionGO:001081020.011
salivary gland morphogenesisGO:00074351450.011
lipid homeostasisGO:0055088330.011
regulation of protein phosphorylationGO:0001932640.011
positive regulation of behaviorGO:0048520190.011
adult behaviorGO:00305341370.011
macromolecular complex assemblyGO:00650032560.011
metal ion homeostasisGO:0055065440.011
Human
purine nucleotide biosynthetic processGO:0006164290.011
imaginal disc derived appendage morphogenesisGO:00351143950.011
regulation of response to nutrient levelsGO:0032107180.011
tube developmentGO:00352952440.011
dendrite self avoidanceGO:007059380.011
carbohydrate metabolic processGO:0005975820.011
response to peptideGO:1901652290.011
response to salt stressGO:0009651110.011
Fly
renal system developmentGO:0072001720.011
nucleotide metabolic processGO:00091171610.011
endocytosisGO:00068973100.011
cell maturationGO:00484691440.011
regulation of cell shapeGO:00083601130.011
chemotaxisGO:00069352490.011
chaeta morphogenesisGO:0008407420.010
retina development in camera type eyeGO:006004140.010
formation of anatomical boundaryGO:0048859370.010
compound eye developmentGO:00487493070.010
negative regulation of protein metabolic processGO:0051248850.010
synapse organizationGO:00508081960.010
regulation of apoptotic processGO:00429811300.010
mapk cascadeGO:00001651070.010
circadian sleep wake cycle sleepGO:0050802230.010
carbohydrate derivative metabolic processGO:19011352170.010
response to drugGO:0042493170.010
male courtship behavior veined wing generated song productionGO:0045433200.010
negative regulation of nitrogen compound metabolic processGO:00511722650.010

ppk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
renal tubular transport diseaseDOID:44700.358
Human
liddle syndromeDOID:005047700.358
Human
kidney diseaseDOID:55700.358
Human
disease of anatomical entityDOID:700.358
Human
urinary system diseaseDOID:1800.358
Human
respiratory system diseaseDOID:157900.307
Human
lower respiratory tract diseaseDOID:005016100.307
Human
bronchial diseaseDOID:117600.275
Human
nervous system diseaseDOID:86300.038
central nervous system diseaseDOID:33100.019
bronchiectasisDOID:956300.013
Human
sensory system diseaseDOID:005015500.010