Drosophila melanogaster

65 known processes

Drp1 (Dmel_CG3210)

Dynamin related protein 1

(Aliases: drp1,Dnm1/Drp1,DRP1,Drp-1,l(2)ND2,drp-1,frat,Drp,CG3210,l(2)22Fd,l(2)ND3,l(2)22Fc,Dmel\CG3210)

Drp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitochondrion morphogenesisGO:007058480.706
cytoskeleton dependent cytokinesisGO:0061640810.670
establishment of localization in cellGO:00516494020.515
intracellular protein transmembrane transportGO:006500240.426
intracellular protein transmembrane importGO:004474340.420
vesicle mediated transportGO:00161923810.355
mitochondrion organizationGO:0007005650.310
sperm mitochondrion organizationGO:003038270.301
meiotic cytokinesisGO:0033206330.292
vesicle localizationGO:0051648550.267
cellular component disassemblyGO:0022411460.257
regulation of cellular component biogenesisGO:00440872010.253
glycosyl compound catabolic processGO:19016581120.240
cellular catabolic processGO:00442483720.238
intracellular transportGO:00469072280.227
male gamete generationGO:00482322010.225
intracellular signal transductionGO:00355563000.220
cellular protein complex disassemblyGO:0043624350.174
synapse organizationGO:00508081960.174
guanosine containing compound metabolic processGO:1901068740.171
regulation of transportGO:00510491810.170
anterior posterior axis specificationGO:00099481090.167
regulation of cellular catabolic processGO:00313291570.166
trna aminoacylationGO:004303920.166
positive regulation of cellular biosynthetic processGO:00313283160.164
cytokinetic processGO:0032506270.162
protein localizationGO:00081042840.148
Mouse
purine nucleotide catabolic processGO:00061951090.144
proteolysisGO:00065081920.144
regulation of protein complex disassemblyGO:0043244290.143
cellular macromolecule localizationGO:00707272200.140
Mouse
regulation of intracellular signal transductionGO:19025312360.134
protein modification processGO:00362114380.133
response to virusGO:0009615280.130
organelle localizationGO:00516401480.129
male meiosis cytokinesisGO:0007112260.128
nucleoside metabolic processGO:00091161270.126
axis specificationGO:00097981670.124
regulation of protein metabolic processGO:00512462560.124
cell divisionGO:00513012480.122
response to external biotic stimulusGO:00432072930.119
protein modification by small protein conjugation or removalGO:00706471060.114
positive regulation of macromolecule metabolic processGO:00106044050.111
single organism biosynthetic processGO:00447112060.110
ribose phosphate metabolic processGO:00196931450.107
negative regulation of cellular metabolic processGO:00313243820.106
macromolecular complex disassemblyGO:0032984370.101
endocytosisGO:00068973100.100
axonogenesisGO:00074092900.098
single organism cellular localizationGO:19025801800.098
spermatogenesisGO:00072832000.095
nucleobase containing compound catabolic processGO:00346551650.091
deathGO:00162652840.090
Mouse
modification dependent macromolecule catabolic processGO:0043632790.088
organelle assemblyGO:00709251980.087
establishment of vesicle localizationGO:0051650510.086
response to biotic stimulusGO:00096072940.083
establishment of mitochondrion localizationGO:005165470.082
actomyosin structure organizationGO:0031032560.082
establishment of protein localizationGO:00451841630.079
organic substance catabolic processGO:19015753080.078
regionalizationGO:00030024160.078
organic substance transportGO:00717022570.078
regulation of catabolic processGO:00098941700.076
chemotaxisGO:00069352490.075
spermatid developmentGO:0007286980.074
transcription from rna polymerase ii promoterGO:00063663680.074
synapse assemblyGO:00074161430.074
ribonucleoside triphosphate metabolic processGO:00091991190.073
regulation of cell shapeGO:00083601130.072
protein modification by small protein removalGO:0070646280.070
purine containing compound metabolic processGO:00725211550.070
purine nucleoside triphosphate catabolic processGO:00091461080.070
nucleoside triphosphate metabolic processGO:00091411200.070
cellular protein catabolic processGO:0044257830.069
small molecule metabolic processGO:00442813050.069
glycosyl compound metabolic processGO:19016571270.069
embryonic axis specificationGO:00005781070.068
regulation of transcription from rna polymerase ii promoterGO:00063573780.067
regulation of localizationGO:00328792750.066
organic cyclic compound catabolic processGO:19013611680.066
cellular protein localizationGO:00346131600.066
Mouse
positive regulation of biosynthetic processGO:00098913160.065
cellular protein modification processGO:00064644380.062
nucleoside triphosphate catabolic processGO:00091431080.061
negative regulation of growthGO:0045926840.061
response to other organismGO:00517072930.060
regulation of mitochondrial fusionGO:001063550.060
protein transmembrane transportGO:007180640.060
gtp metabolic processGO:0046039720.059
negative regulation of signalingGO:00230572190.059
organophosphate metabolic processGO:00196371950.058
apoptotic processGO:00069151590.057
eye developmentGO:00016543230.056
organonitrogen compound metabolic processGO:19015643180.054
regulation of oocyte developmentGO:0060281270.054
establishment of organelle localizationGO:00516561220.053
regulation of phosphorus metabolic processGO:00511742100.052
purine containing compound catabolic processGO:00725231120.051
ribonucleotide metabolic processGO:00092591450.051
regulation of molecular functionGO:00650092170.050
translationGO:0006412690.049
purine ribonucleotide catabolic processGO:00091541090.049
imaginal disc derived appendage morphogenesisGO:00351143950.049
protein transportGO:00150311550.048
protein complex assemblyGO:00064612000.048
imaginal disc derived wing morphogenesisGO:00074763370.047
cytoplasmic transportGO:00164821300.047
carbohydrate derivative catabolic processGO:19011361180.047
purine ribonucleoside triphosphate catabolic processGO:00092071080.047
nucleotide catabolic processGO:00091661090.047
embryonic pattern specificationGO:00098801740.046
protein complex disassemblyGO:0043241360.046
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.046
dorsal ventral pattern formationGO:00099531330.046
cytokinesisGO:0000910900.045
catabolic processGO:00090564090.045
compound eye morphogenesisGO:00017452490.045
nucleoside catabolic processGO:00091641120.044
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.044
regulation of organelle organizationGO:00330431960.043
neuromuscular junction developmentGO:00075281490.041
brain developmentGO:00074201200.041
eye morphogenesisGO:00485922600.041
positive regulation of cellular catabolic processGO:0031331950.041
purine ribonucleoside catabolic processGO:00461301120.040
homeostatic processGO:00425921990.040
purine nucleoside triphosphate metabolic processGO:00091441190.040
meiotic spindle organizationGO:0000212360.040
agingGO:00075681430.040
regulation of cellular protein metabolic processGO:00322682430.039
purine nucleoside metabolic processGO:00422781270.039
multi organism reproductive behaviorGO:00447051210.039
establishment of protein localization to organelleGO:0072594620.038
oocyte differentiationGO:00099941450.038
ribonucleoside metabolic processGO:00091191270.038
protein catabolic processGO:00301631010.037
negative regulation of cellular component organizationGO:00511291080.037
appendage developmentGO:00487364010.037
positive regulation of macromolecule biosynthetic processGO:00105572830.037
meiosis iiGO:0007135230.037
regulation of protein depolymerizationGO:1901879270.037
cytoplasm organizationGO:0007028640.036
wing disc morphogenesisGO:00074723440.036
positive regulation of catabolic processGO:00098961050.036
nuclear transportGO:0051169720.036
transmembrane transportGO:00550851390.036
programmed cell deathGO:00125012570.035
Mouse
anterior posterior axis specification embryoGO:00085951030.035
amino acid activationGO:004303830.034
contractile ring contractionGO:0036213120.034
single organism intracellular transportGO:19025822070.034
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.034
morphogenesis of an epitheliumGO:00020092760.033
protein localization to organelleGO:0033365820.033
Mouse
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.033
regulation of cell deathGO:00109411730.033
negative regulation of cell communicationGO:00106482230.033
protein processingGO:0016485680.033
axon guidanceGO:00074112330.032
intracellular protein transportGO:00068861040.032
nucleobase containing small molecule metabolic processGO:00550861740.032
regulation of phosphorylationGO:00423251470.031
sensory organ morphogenesisGO:00905962600.031
positive regulation of cellular protein metabolic processGO:00322701180.031
negative regulation of signal transductionGO:00099682060.030
regulation of multicellular organismal developmentGO:20000264140.030
nucleotide metabolic processGO:00091171610.030
tripartite regional subdivisionGO:00073511030.030
ribonucleoside triphosphate catabolic processGO:00092031080.029
retina development in camera type eyeGO:006004140.029
regulation of cellular amine metabolic processGO:003323830.029
negative regulation of response to oxidative stressGO:190288310.029
cell motilityGO:00488702510.029
larval developmentGO:00021641040.029
positive regulation of response to stimulusGO:00485843230.029
regulation of cell proliferationGO:00421271630.028
regulation of synaptic growth at neuromuscular junctionGO:0008582890.028
carbohydrate derivative metabolic processGO:19011352170.028
sensory perceptionGO:00076001960.028
appendage morphogenesisGO:00351073970.027
organophosphate catabolic processGO:00464341120.027
central nervous system developmentGO:00074172010.027
positive regulation of gene expressionGO:00106282900.027
negative regulation of protein depolymerizationGO:1901880230.027
regulation of meiosisGO:004002030.027
heterocycle catabolic processGO:00467001660.027
positive regulation of nitrogen compound metabolic processGO:00511733540.026
protein maturationGO:0051604710.026
embryo development ending in birth or egg hatchingGO:00097921520.026
forebrain developmentGO:003090020.026
spermatid differentiationGO:00485151140.026
axon developmentGO:00615642970.026
cellular macromolecule catabolic processGO:00442651360.026
purine nucleoside catabolic processGO:00061521120.026
mitochondrial fissionGO:000026680.026
cellular nitrogen compound catabolic processGO:00442701650.026
guanosine containing compound catabolic processGO:1901069740.026
autophagyGO:00069141080.026
negative regulation of organelle organizationGO:0010639560.025
post embryonic appendage morphogenesisGO:00351203850.025
imaginal disc derived appendage developmentGO:00487373990.025
blastoderm segmentationGO:00073501590.025
positive regulation of molecular functionGO:00440931360.025
localization of cellGO:00516742570.025
regulation of cell maturationGO:1903429270.025
oocyte anterior posterior axis specificationGO:0007314720.025
positive regulation of cellular amino acid metabolic processGO:004576400.025
extracellular structure organizationGO:0043062460.025
tissue morphogenesisGO:00487292970.025
embryonic morphogenesisGO:00485982060.024
purine ribonucleoside triphosphate metabolic processGO:00092051190.024
mitochondrion degradationGO:000042280.024
protein targeting to mitochondrionGO:000662610.024
nucleoside phosphate metabolic processGO:00067531620.024
cellular amino acid metabolic processGO:0006520610.024
organic acid metabolic processGO:00060821030.023
positive regulation of hydrolase activityGO:0051345780.023
positive regulation of signalingGO:00230562430.023
positive regulation of intracellular signal transductionGO:19025331160.023
dorsal closureGO:0007391790.023
posttranscriptional regulation of gene expressionGO:00106081450.023
protein deubiquitinationGO:0016579170.023
ubiquitin dependent protein catabolic processGO:0006511780.023
positive regulation of cell communicationGO:00106472500.023
proteolysis involved in cellular protein catabolic processGO:0051603830.022
positive regulation of cellular component organizationGO:00511301560.022
protein depolymerizationGO:0051261310.022
cell deathGO:00082192790.022
Mouse
positive regulation of cellular protein catabolic processGO:1903364240.022
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.022
positive regulation of rna biosynthetic processGO:19026802660.022
regulation of programmed cell deathGO:00430671520.022
segmentationGO:00352822070.021
phosphorylationGO:00163102940.021
neuromuscular synaptic transmissionGO:0007274670.021
protein ubiquitinationGO:0016567700.021
ribonucleotide catabolic processGO:00092611090.021
ubiquitin homeostasisGO:001099210.021
positive regulation of phosphate metabolic processGO:00459371390.021
anterior posterior pattern specificationGO:00099521360.021
regulation of embryonic pattern specificationGO:1902875270.021
regulation of synapse structure and activityGO:00508031280.021
dna metabolic processGO:00062592270.021
positive regulation of nucleotide catabolic processGO:0030813460.020
negative regulation of cellular response to oxidative stressGO:190040810.020
response to organic substanceGO:00100332840.020
positive regulation of transportGO:0051050920.020
peptide metabolic processGO:0006518800.020
protein targetingGO:0006605640.020
cellular response to chemical stimulusGO:00708871990.020
trna aminoacylation for protein translationGO:000641820.019
maternal determination of anterior posterior axis embryoGO:0008358740.019
protein phosphorylationGO:00064681690.019
mitochondrial fusionGO:000805370.019
regulation of proteolysisGO:0030162870.019
regulation of cellular response to oxidative stressGO:190040740.019
establishment or maintenance of bipolar cell polarityGO:0061245340.019
protein localization to mitochondrionGO:007058510.019
Mouse
retina morphogenesis in camera type eyeGO:006004220.019
developmental growthGO:00485892800.019
body morphogenesisGO:001017120.018
sperm individualizationGO:0007291480.018
growthGO:00400073590.018
negative regulation of catabolic processGO:0009895360.018
positive regulation of protein catabolic processGO:0045732340.018
secretionGO:00469031090.017
regulation of establishment of protein localization to plasma membraneGO:009000370.017
purine nucleotide metabolic processGO:00061631460.017
camera type eye developmentGO:004301040.017
macromolecular complex assemblyGO:00650032560.017
regulation of g protein coupled receptor protein signaling pathwayGO:0008277230.017
purine ribonucleoside metabolic processGO:00461281270.017
regulation of cellular protein catabolic processGO:1903362440.017
regulation of microtubule based processGO:0032886490.017
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.017
taxisGO:00423303040.017
single organism catabolic processGO:00447122280.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of protein catabolic processGO:0042176550.017
photoreceptor cell maintenanceGO:0045494110.017
multicellular organismal agingGO:00102591400.016
gtp catabolic processGO:0006184720.016
protein modification by small protein conjugationGO:0032446790.016
mitotic g2 dna damage checkpointGO:0007095690.016
negative regulation of response to stimulusGO:00485852580.016
meiotic nuclear divisionGO:00071261510.016
regulation of protein modification processGO:00313991120.016
regulation of mapk cascadeGO:0043408920.016
small gtpase mediated signal transductionGO:0007264880.015
positive regulation of catalytic activityGO:00430851180.015
regulation of synapse assemblyGO:0051963940.015
golgi to plasma membrane protein transportGO:004300180.015
ribonucleoside monophosphate metabolic processGO:0009161510.015
regulation of cell developmentGO:00602842150.015
matingGO:00076181200.015
cellular respirationGO:0045333260.015
regulation of protein phosphorylationGO:0001932640.015
mating behaviorGO:00076171060.015
negative regulation of autophagyGO:0010507160.015
cell migrationGO:00164772380.015
regulation of small gtpase mediated signal transductionGO:0051056930.015
epithelial cell differentiationGO:00308553220.015
regulation of translationGO:0006417560.015
meiosis iGO:0007127590.015
actomyosin contractile ring contractionGO:0000916120.015
regulation of reproductive processGO:2000241540.014
regulation of catalytic activityGO:00507901850.014
ribonucleoside monophosphate catabolic processGO:0009158390.014
positive regulation of phosphorus metabolic processGO:00105621390.014
positive regulation of cell deathGO:0010942690.014
morphogenesis of embryonic epitheliumGO:0016331940.014
regulation of protein localizationGO:0032880760.014
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.014
intracellular mrna localization involved in pattern specification processGO:0060810560.014
response to dsrnaGO:0043331150.014
regulation of vesicle mediated transportGO:0060627590.014
gastrulation involving germ band extensionGO:0010004360.014
negative regulation of cytoskeleton organizationGO:0051494300.014
compound eye developmentGO:00487493070.013
regulation of cytoplasmic transportGO:1903649470.013
histone modificationGO:00165701060.013
aromatic compound catabolic processGO:00194391660.013
regulation of intracellular transportGO:0032386640.013
negative regulation of cellular catabolic processGO:0031330340.013
pole plasm mrna localizationGO:0019094490.013
regulation of microtubule cytoskeleton organizationGO:0070507410.013
positive regulation of phosphorylationGO:0042327870.013
oocyte developmentGO:00485991240.013
regulation of phosphate metabolic processGO:00192202100.013
negative regulation of protein metabolic processGO:0051248850.013
response to temperature stimulusGO:00092661060.013
er associated ubiquitin dependent protein catabolic processGO:003043330.013
establishment of mitochondrion localization microtubule mediatedGO:003464360.013
single organism nuclear importGO:1902593510.013
purine ribonucleotide metabolic processGO:00091501450.013
anatomical structure homeostasisGO:0060249970.012
positive regulation of mapk cascadeGO:0043410630.012
regulation of synapse organizationGO:00508071100.012
nephron developmentGO:007200630.012
negative regulation of cell deathGO:0060548810.012
determination of adult lifespanGO:00083401370.012
protein polymerizationGO:0051258420.012
positive regulation of nucleobase containing compound metabolic processGO:00459353320.012
hemopoiesisGO:0030097460.012
mitotic g2 m transition checkpointGO:0044818700.012
regulation of mrna 3 end processingGO:003144070.012
lamellipodium assemblyGO:0030032210.012
production of small rna involved in gene silencing by rnaGO:0070918150.012
establishment of tissue polarityGO:0007164870.012
synaptic transmissionGO:00072682880.011
actin filament organizationGO:00070151260.011
neuron deathGO:0070997270.011
synaptic vesicle transportGO:0048489500.011
regulation of symbiosis encompassing mutualism through parasitismGO:0043903150.011
spindle assemblyGO:0051225800.011
regulation of mitotic cell cycleGO:00073461900.011
response to heatGO:0009408630.011
purine ribonucleoside monophosphate metabolic processGO:0009167500.011
regulation of protein polymerizationGO:0032271280.011
synaptic vesicle recyclingGO:0036465280.011
regulation of intracellular protein transportGO:0033157460.011
detection of light stimulus involved in sensory perceptionGO:005096290.011
regulation of cell cycleGO:00517262910.011
cellular response to oxygen containing compoundGO:1901701790.011
regulation of protein stabilityGO:0031647430.011
mapk cascadeGO:00001651070.011
regulation of multi organism processGO:00439001310.011
regulation of nucleoside metabolic processGO:0009118500.011
synaptic vesicle localizationGO:0097479530.011
negative regulation of protein processingGO:0010955310.011
mitotic nuclear divisionGO:00070672130.011
metal ion transportGO:0030001740.010
entry into cell of other organism involved in symbiotic interactionGO:005180630.010
meiotic cell cycleGO:00513211710.010
regulation of i kappab kinase nf kappab signalingGO:004312220.010
dna templated transcription elongationGO:0006354180.010
cation transportGO:00068121100.010
tube developmentGO:00352952440.010
epithelial cell developmentGO:00020642740.010
positive regulation of signal transductionGO:00099672230.010
regulation of protein processingGO:0070613320.010
purine nucleoside monophosphate metabolic processGO:0009126500.010
male pronucleus assemblyGO:003503960.010
inorganic cation transmembrane transportGO:0098662610.010
mitotic cell cycle phase transitionGO:00447721380.010
regulation of protein modification by small protein conjugation or removalGO:1903320250.010

Drp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.014
disease of cellular proliferationDOID:1456600.011