Drosophila melanogaster

98 known processes

Doc1 (Dmel_CG5133)

Dorsocross1

(Aliases: Tb66F2,Ect2,Doc,doc1,CG5133,Dm-DOC1,doc,Dmel\CG5133)

Doc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of rna metabolic processGO:00512532510.298
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.250
Fly
regulation of cell differentiationGO:00455953020.245
Fly
negative regulation of cellular metabolic processGO:00313243820.224
Fly
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.220
post embryonic appendage morphogenesisGO:00351203850.216
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.189
Fly
imaginal disc derived appendage developmentGO:00487373990.179
Fly
appendage morphogenesisGO:00351073970.178
Fly
imaginal disc derived appendage morphogenesisGO:00351143950.165
Fly
transcription from rna polymerase ii promoterGO:00063663680.156
malpighian tubule developmentGO:0072002640.156
sensory organ morphogenesisGO:00905962600.141
Fly
negative regulation of transcription dna templatedGO:00458922370.137
Fly
regulation of multicellular organismal developmentGO:20000264140.134
negative regulation of rna biosynthetic processGO:19026792400.133
Fly
columnar cuboidal epithelial cell developmentGO:00020662490.131
Fly
regulation of transcription from rna polymerase ii promoterGO:00063573780.131
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.130
Fly
chorion containing eggshell formationGO:00073041050.130
Fly
epithelial cell differentiationGO:00308553220.129
Fly
appendage developmentGO:00487364010.128
Fly
regionalizationGO:00030024160.128
Fly
negative regulation of gene expressionGO:00106293870.127
Fly
eye developmentGO:00016543230.126
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.123
positive regulation of nucleic acid templated transcriptionGO:19035082660.111
determination of imaginal disc primordiumGO:0007445110.111
malpighian tubule morphogenesisGO:0007443440.110
positive regulation of nitrogen compound metabolic processGO:00511733540.110
negative regulation of nucleic acid templated transcriptionGO:19035072400.107
Fly
negative regulation of cellular biosynthetic processGO:00313272770.098
Fly
positive regulation of macromolecule biosynthetic processGO:00105572830.091
embryonic morphogenesisGO:00485982060.090
growthGO:00400073590.089
Fly
negative regulation of nucleobase containing compound metabolic processGO:00459342610.087
Fly
positive regulation of cellular biosynthetic processGO:00313283160.085
positive regulation of macromolecule metabolic processGO:00106044050.082
cardiocyte differentiationGO:0035051290.081
wing disc morphogenesisGO:00074723440.080
Fly
columnar cuboidal epithelial cell differentiationGO:00020652560.079
Fly
epithelial cell developmentGO:00020642740.078
Fly
positive regulation of rna metabolic processGO:00512542710.075
positive regulation of transcription dna templatedGO:00458932660.073
compound eye developmentGO:00487493070.073
Fly
positive regulation of rna biosynthetic processGO:19026802660.068
eggshell formationGO:00307031050.065
Fly
camera type eye developmentGO:004301040.064
positive regulation of gene expressionGO:00106282900.064
compound eye morphogenesisGO:00017452490.064
Fly
leg disc developmentGO:0035218920.063
Fly
immune system processGO:00023763470.058
small molecule metabolic processGO:00442813050.057
cell fate specificationGO:0001708710.057
Fly
oxoacid metabolic processGO:00434361030.056
stem cell differentiationGO:00488631170.055
Fly
cell migrationGO:00164772380.054
circulatory system developmentGO:0072359820.053
negative regulation of biosynthetic processGO:00098902770.050
Fly
endocytosisGO:00068973100.049
tube morphogenesisGO:00352391910.049
organonitrogen compound metabolic processGO:19015643180.047
organonitrogen compound biosynthetic processGO:19015661170.047
renal tubule developmentGO:0061326640.046
heart processGO:0003015370.046
Fly
wing disc pattern formationGO:0035222660.046
Fly
imaginal disc derived wing morphogenesisGO:00074763370.046
Fly
digestive tract developmentGO:00485651490.045
organelle fissionGO:00482853400.044
tissue morphogenesisGO:00487292970.044
organ growthGO:0035265560.044
Fly
negative regulation of developmental processGO:00510932010.043
morphogenesis of an epitheliumGO:00020092760.043
hindgut morphogenesisGO:0007442580.043
segmentationGO:00352822070.043
embryo development ending in birth or egg hatchingGO:00097921520.042
somatic muscle developmentGO:0007525660.042
Fly
hindgut developmentGO:0061525580.041
cell motilityGO:00488702510.039
regulation of cell fate specificationGO:0042659270.039
Fly
regulation of cell fate commitmentGO:0010453290.039
Fly
eye morphogenesisGO:00485922600.039
Fly
cardioblast differentiationGO:0010002200.038
Fly
response to abiotic stimulusGO:00096283410.037
imaginal disc pattern formationGO:0007447910.037
Fly
nucleotide metabolic processGO:00091171610.037
anterior posterior pattern specificationGO:00099521360.036
Fly
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.035
Fly
renal system developmentGO:0072001720.035
cell deathGO:00082192790.034
organophosphate metabolic processGO:00196371950.033
embryonic hindgut morphogenesisGO:0048619480.032
chaeta developmentGO:0022416970.031
muscle structure developmentGO:00610612240.031
Fly
digestive tract morphogenesisGO:00485461270.031
anterior posterior axis specification embryoGO:00085951030.031
negative regulation of multicellular organismal processGO:00512411420.030
regulation of localizationGO:00328792750.030
ovarian follicle cell developmentGO:00307072480.030
Fly
phagocytosisGO:00069092150.029
sterol homeostasisGO:005509240.029
carboxylic acid metabolic processGO:0019752920.029
vesicle mediated transportGO:00161923810.029
deathGO:00162652840.029
response to oxygen containing compoundGO:19017002000.028
digestive system developmentGO:00551231490.028
nucleobase containing small molecule metabolic processGO:00550861740.028
connective tissue developmentGO:006144830.028
developmental maturationGO:00217001720.027
synaptic transmissionGO:00072682880.027
nucleoside phosphate metabolic processGO:00067531620.027
regulation of nervous system developmentGO:00519602480.027
circulatory system processGO:0003013370.027
Fly
kidney developmentGO:000182230.027
cardiovascular system developmentGO:0072358820.027
stem cell proliferationGO:0072089880.027
localization of cellGO:00516742570.026
positive regulation of biosynthetic processGO:00098913160.026
telencephalon developmentGO:002153720.025
cell maturationGO:00484691440.025
carbohydrate derivative metabolic processGO:19011352170.025
blastoderm segmentationGO:00073501590.025
regulation of neurogenesisGO:00507671580.024
limb developmentGO:006017310.024
developmental growthGO:00485892800.024
axis specificationGO:00097981670.024
programmed cell deathGO:00125012570.023
cellular response to chemical stimulusGO:00708871990.023
tripartite regional subdivisionGO:00073511030.022
oocyte differentiationGO:00099941450.022
embryonic axis specificationGO:00005781070.022
organic hydroxy compound metabolic processGO:1901615830.022
positive regulation of signal transductionGO:00099672230.022
protein modification processGO:00362114380.022
kidney epithelium developmentGO:007207330.022
regulation of cell deathGO:00109411730.022
kidney morphogenesisGO:006099330.022
single organism biosynthetic processGO:00447112060.021
positive regulation of signalingGO:00230562430.021
negative regulation of programmed cell deathGO:0043069720.021
enzyme linked receptor protein signaling pathwayGO:00071671790.021
tissue migrationGO:00901301550.021
regulation of cell developmentGO:00602842150.020
dorsal ventral pattern formationGO:00099531330.020
response to organic substanceGO:00100332840.020
central nervous system developmentGO:00074172010.020
regulation of organelle organizationGO:00330431960.020
positive regulation of response to stimulusGO:00485843230.020
male gamete generationGO:00482322010.020
positive regulation of cellular component organizationGO:00511301560.019
urogenital system developmentGO:0001655720.019
anterior posterior axis specificationGO:00099481090.019
response to external biotic stimulusGO:00432072930.019
response to organophosphorusGO:004668320.019
spermatid differentiationGO:00485151140.019
epithelial tube morphogenesisGO:0060562880.019
tube developmentGO:00352952440.019
organic acid metabolic processGO:00060821030.019
regulation of cell proliferationGO:00421271630.019
photoreceptor cell differentiationGO:00465301700.019
cellular protein modification processGO:00064644380.018
response to alcoholGO:0097305950.018
response to biotic stimulusGO:00096072940.018
macromolecular complex assemblyGO:00650032560.018
body morphogenesisGO:001017120.018
establishment of localization in cellGO:00516494020.018
forebrain developmentGO:003090020.018
response to other organismGO:00517072930.018
regulation of cellular amino acid metabolic processGO:000652100.018
sensory perceptionGO:00076001960.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.017
single organism behaviorGO:00447083910.017
apoptotic processGO:00069151590.017
immune responseGO:00069552460.017
mitotic nuclear divisionGO:00070672130.017
heart developmentGO:0007507820.017
renal tubule morphogenesisGO:0061333440.017
negative regulation of response to stimulusGO:00485852580.017
regulation of catabolic processGO:00098941700.017
catabolic processGO:00090564090.017
response to lipopolysaccharideGO:003249640.017
regulation of embryonic developmentGO:0045995680.017
regulation of intracellular signal transductionGO:19025312360.016
lipid metabolic processGO:00066291210.016
regulation of apoptotic processGO:00429811300.016
regulation of growthGO:00400082330.016
purine nucleotide metabolic processGO:00061631460.016
small gtpase mediated signal transductionGO:0007264880.016
embryonic development via the syncytial blastodermGO:00017001480.016
pyridine nucleotide metabolic processGO:001936220.016
gland morphogenesisGO:00226121450.016
cellular lipid metabolic processGO:0044255830.016
carbohydrate metabolic processGO:0005975820.016
oocyte developmentGO:00485991240.016
regulation of developmental growthGO:00486381740.016
ras protein signal transductionGO:0007265880.016
regulation of programmed cell deathGO:00430671520.016
proteolysisGO:00065081920.015
neurological system processGO:00508773580.015
regulation of epithelial cell differentiationGO:003085640.015
taxisGO:00423303040.015
regulation of cell morphogenesis involved in differentiationGO:0010769610.015
ameboidal type cell migrationGO:00016671510.015
positive regulation of hydrolase activityGO:0051345780.015
cellular catabolic processGO:00442483720.015
pharynx developmentGO:006046510.015
regulation of cellular amine metabolic processGO:003323830.015
single organism carbohydrate metabolic processGO:0044723720.015
chemotaxisGO:00069352490.015
negative regulation of signal transductionGO:00099682060.015
oxidoreduction coenzyme metabolic processGO:000673320.015
retina development in camera type eyeGO:006004140.015
oxidation reduction processGO:00551141230.015
positive regulation of multicellular organismal processGO:00512401430.015
regulation of anatomical structure morphogenesisGO:00226032420.015
regulation of immune system processGO:00026821760.015
cellular amine metabolic processGO:0044106120.014
purine containing compound metabolic processGO:00725211550.014
single organism catabolic processGO:00447122280.014
regulation of response to stressGO:00801342000.014
regulation of molecular functionGO:00650092170.014
morphogenesis of embryonic epitheliumGO:0016331940.014
nucleoside triphosphate metabolic processGO:00091411200.014
regulation of transportGO:00510491810.014
leg disc morphogenesisGO:0007478800.014
positive regulation of cell communicationGO:00106472500.014
response to starvationGO:0042594970.014
cell proliferationGO:00082832990.014
cellular response to organic substanceGO:00713101320.014
actin filament based processGO:00300292200.014
agingGO:00075681430.014
regulation of cellular ketone metabolic processGO:001056530.014
limb morphogenesisGO:003510810.014
eye photoreceptor cell differentiationGO:00017541450.013
ribonucleotide metabolic processGO:00092591450.013
nicotinamide nucleotide metabolic processGO:004649620.013
nuclear divisionGO:00002803320.013
detection of stimulus involved in sensory perceptionGO:0050906920.013
dna metabolic processGO:00062592270.013
oocyte constructionGO:00073081120.013
epithelium migrationGO:00901321480.013
chromosome organizationGO:00512763600.013
wound healingGO:0042060750.013
nephron epithelium developmentGO:007200930.013
regulation of response to external stimulusGO:00321011150.013
organelle assemblyGO:00709251980.013
regulation of catalytic activityGO:00507901850.013
mitotic spindle organizationGO:00070522200.013
positive regulation of nucleoside metabolic processGO:0045979470.013
regulation of epithelial cell proliferationGO:005067840.013
regulation of neuron differentiationGO:00456641030.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
positive regulation of developmental processGO:00510941430.013
regulation of cellular localizationGO:00603411360.013
protein complex biogenesisGO:00702712010.013
negative regulation of cellular component organizationGO:00511291080.013
eye antennal disc developmentGO:0035214600.013
cellular amino acid metabolic processGO:0006520610.013
ribonucleotide catabolic processGO:00092611090.013
regulation of phosphorus metabolic processGO:00511742100.013
regulation of multi organism processGO:00439001310.013
mesenchymal cell differentiationGO:004876210.012
amine metabolic processGO:0009308120.012
negative regulation of cell communicationGO:00106482230.012
purine ribonucleotide metabolic processGO:00091501450.012
innate immune responseGO:00450871440.012
single organism cellular localizationGO:19025801800.012
gastrulationGO:0007369700.012
embryonic organ developmentGO:0048568500.012
Fly
rna localizationGO:00064031150.012
cellular response to dna damage stimulusGO:00069742230.012
regulation of phosphate metabolic processGO:00192202100.012
spindle organizationGO:00070512530.012
nephron developmentGO:007200630.012
salivary gland developmentGO:00074311620.012
hematopoietic progenitor cell differentiationGO:000224410.012
immune system developmentGO:0002520570.012
regulation of cellular component biogenesisGO:00440872010.012
phosphorylationGO:00163102940.012
ribonucleoside metabolic processGO:00091191270.012
wnt signaling pathwayGO:0016055980.012
regulation of cell projection organizationGO:0031344920.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
antennal developmentGO:0007469250.012
organic substance catabolic processGO:19015753080.012
spermatid developmentGO:0007286980.012
regulation of immune responseGO:00507761180.012
mesoderm developmentGO:0007498780.012
purine nucleotide catabolic processGO:00061951090.012
peptide metabolic processGO:0006518800.012
axon developmentGO:00615642970.011
regulation of neuron projection developmentGO:0010975690.011
mushroom body developmentGO:0016319700.011
skeletal muscle fiber developmentGO:004874130.011
epithelial cell migrationGO:00106311480.011
intracellular signal transductionGO:00355563000.011
determination of adult lifespanGO:00083401370.011
regulation of cell morphogenesisGO:00226041630.011
response to radiationGO:00093141550.011
defense response to other organismGO:00985422250.011
axon guidanceGO:00074112330.011
oocyte axis specificationGO:00073091080.011
microtubule based movementGO:0007018510.011
detection of chemical stimulus involved in sensory perceptionGO:0050907750.011
intracellular transportGO:00469072280.011
cellular protein localizationGO:00346131600.011
chromosome segregationGO:00070591570.011
regulation of cellular protein metabolic processGO:00322682430.011
positive regulation of catabolic processGO:00098961050.011
midgut developmentGO:0007494230.011
ribose phosphate metabolic processGO:00196931450.011
purine ribonucleoside catabolic processGO:00461301120.011
response to woundingGO:0009611940.011
gliogenesisGO:0042063800.011
chorion containing eggshell pattern formationGO:0030381110.011
Fly
homeostatic processGO:00425921990.011
response to nutrient levelsGO:00316671140.011
respiratory system developmentGO:00605412130.011
foregut morphogenesisGO:0007440100.011
ribonucleoside triphosphate catabolic processGO:00092031080.010
antimicrobial humoral responseGO:0019730990.010
cell divisionGO:00513012480.010
regulation of protein metabolic processGO:00512462560.010
negative regulation of neurogenesisGO:0050768530.010
positive regulation of cellular amine metabolic processGO:003324000.010
positive regulation of cellular catabolic processGO:0031331950.010
chromatin remodelingGO:0006338720.010
positive regulation of cell migrationGO:003033520.010
posttranscriptional regulation of gene expressionGO:00106081450.010
negative regulation of cell differentiationGO:00455961430.010
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.010
endomembrane system organizationGO:00102561190.010
regulation of cell cycleGO:00517262910.010
purine ribonucleotide catabolic processGO:00091541090.010
negative regulation of nervous system developmentGO:0051961920.010
chemical homeostasisGO:0048878920.010
ribonucleoside triphosphate metabolic processGO:00091991190.010
response to temperature stimulusGO:00092661060.010
positive regulation of growthGO:0045927750.010
purine nucleoside metabolic processGO:00422781270.010
maternal determination of anterior posterior axis embryoGO:0008358740.010
regulation of vesicle mediated transportGO:0060627590.010

Doc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.017
sensory system diseaseDOID:005015500.010
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010