Drosophila melanogaster

55 known processes

Mcm5 (Dmel_CG4082)

Minichromosome maintenance 5

(Aliases: CG4082,DmMcm5,DmCDC465,McM5,DmMCM5,MCM5,mcm5,PCR4,DmeMCM5,Dmel\CG4082,DmCDC46)

Mcm5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nuclear dna replicationGO:003326010.992
Yeast
dna recombinationGO:0006310320.911
meiotic chromosome segregationGO:0045132590.834
dna metabolic processGO:00062592270.829
dna packagingGO:0006323910.733
reciprocal meiotic recombinationGO:0007131190.674
dna replication initiationGO:000627060.640
Yeast
dna replicationGO:0006260480.620
organelle fissionGO:00482853400.571
dna geometric changeGO:0032392160.553
cell cycle dna replicationGO:0044786230.551
double strand break repair via homologous recombinationGO:0000724130.549
Yeast
macromolecular complex assemblyGO:00650032560.508
Yeast
chromosome condensationGO:0030261410.446
dna conformation changeGO:00711031050.430
cellular macromolecular complex assemblyGO:00346221530.426
Yeast
spindle organizationGO:00070512530.422
double strand break repairGO:0006302260.391
Yeast
cellular catabolic processGO:00442483720.378
Yeast
negative regulation of cellular metabolic processGO:00313243820.366
Yeast
meiotic cell cycleGO:00513211710.365
catabolic processGO:00090564090.346
Yeast
dna repairGO:0006281540.334
Yeast
nucleobase containing compound catabolic processGO:00346551650.328
Yeast
negative regulation of nitrogen compound metabolic processGO:00511722650.321
Yeast
deathGO:00162652840.299
Zebrafish
protein dna complex assemblyGO:0065004630.289
Yeast
meiotic nuclear divisionGO:00071261510.289
dna endoreduplicationGO:0042023220.279
nuclear divisionGO:00002803320.265
ribonucleoside monophosphate catabolic processGO:0009158390.231
Yeast
mitotic spindle organizationGO:00070522200.226
protein complex biogenesisGO:00702712010.221
cell deathGO:00082192790.207
Zebrafish
aromatic compound catabolic processGO:00194391660.204
Yeast
chromosome segregationGO:00070591570.195
heterocycle catabolic processGO:00467001660.181
Yeast
male meiosisGO:0007140520.179
positive regulation of macromolecule metabolic processGO:00106044050.177
Yeast
recombinational repairGO:0000725130.171
Yeast
organic substance catabolic processGO:19015753080.167
Yeast
cellular nitrogen compound catabolic processGO:00442701650.163
Yeast
negative regulation of cell cycle processGO:00109481090.162
g2 dna damage checkpointGO:0031572690.158
female meiotic divisionGO:0007143700.154
carbohydrate derivative metabolic processGO:19011352170.150
Yeast
protein complex assemblyGO:00064612000.143
dna dependent dna replicationGO:0006261170.138
Yeast
small molecule metabolic processGO:00442813050.133
Yeast
protein dna complex subunit organizationGO:0071824860.128
Yeast
regulation of catabolic processGO:00098941700.124
regulation of phosphate metabolic processGO:00192202100.123
organic cyclic compound catabolic processGO:19013611680.120
Yeast
protein localizationGO:00081042840.119
regulation of hydrolase activityGO:0051336970.109
purine containing compound metabolic processGO:00725211550.105
Yeast
cellular response to dna damage stimulusGO:00069742230.098
Yeast
mitotic g2 m transition checkpointGO:0044818700.096
atp metabolic processGO:0046034490.089
Yeast
negative regulation of mitotic cell cycle phase transitionGO:19019911030.085
chromosome separationGO:0051304420.083
spindle assembly involved in mitosisGO:0090307500.083
cellular macromolecule localizationGO:00707272200.081
regulation of dna metabolic processGO:0051052340.079
Yeast
establishment of localization in cellGO:00516494020.078
regulation of cell cycle phase transitionGO:19019871300.076
single organism biosynthetic processGO:00447112060.073
organonitrogen compound metabolic processGO:19015643180.073
Yeast
embryo development ending in birth or egg hatchingGO:00097921520.071
Worm
mitotic cell cycle phase transitionGO:00447721380.070
mitotic cell cycle checkpointGO:0007093880.068
negative regulation of nucleobase containing compound metabolic processGO:00459342610.068
Yeast
regulation of catalytic activityGO:00507901850.068
single organism catabolic processGO:00447122280.067
Yeast
mitotic nuclear divisionGO:00070672130.067
programmed cell deathGO:00125012570.066
Zebrafish
proteolysisGO:00065081920.062
purine ribonucleoside triphosphate metabolic processGO:00092051190.061
Yeast
cell motilityGO:00488702510.060
chromosome organizationGO:00512763600.060
regulation of cell cycle processGO:00105641810.059
sister chromatid segregationGO:0000819920.058
ribonucleoside triphosphate catabolic processGO:00092031080.058
Yeast
mitotic g2 dna damage checkpointGO:0007095690.057
purine ribonucleoside metabolic processGO:00461281270.056
Yeast
purine ribonucleotide catabolic processGO:00091541090.056
Yeast
nucleoside catabolic processGO:00091641120.055
Yeast
cellular protein complex assemblyGO:0043623710.055
establishment of protein localizationGO:00451841630.054
regulation of molecular functionGO:00650092170.054
purine nucleoside triphosphate metabolic processGO:00091441190.054
Yeast
positive regulation of catalytic activityGO:00430851180.054
ribonucleoside metabolic processGO:00091191270.052
Yeast
glycosyl compound catabolic processGO:19016581120.052
Yeast
apoptotic processGO:00069151590.051
Zebrafish
protein modification by small protein conjugationGO:0032446790.050
glycosyl compound metabolic processGO:19016571270.050
Yeast
ribose phosphate metabolic processGO:00196931450.050
Yeast
mitotic chromosome condensationGO:0007076220.049
cell divisionGO:00513012480.048
single organism cellular localizationGO:19025801800.048
chromatin silencingGO:0006342760.047
Yeast
nucleobase containing small molecule metabolic processGO:00550861740.047
Yeast
purine ribonucleoside catabolic processGO:00461301120.046
Yeast
reproductive structure developmentGO:0048608740.046
female meiosis chromosome segregationGO:0016321330.045
purine nucleotide catabolic processGO:00061951090.044
Yeast
reproductive system developmentGO:0061458740.044
cell cycle checkpointGO:0000075950.044
purine nucleotide metabolic processGO:00061631460.044
Yeast
nucleoside metabolic processGO:00091161270.044
Yeast
centrosome organizationGO:00512971630.044
dna amplificationGO:0006277110.043
male gamete generationGO:00482322010.043
regulation of mitotic cell cycle phase transitionGO:19019901300.042
purine nucleoside catabolic processGO:00061521120.042
Yeast
microtubule cytoskeleton organization involved in mitosisGO:1902850520.041
purine nucleoside metabolic processGO:00422781270.041
Yeast
protein transportGO:00150311550.040
spindle assemblyGO:0051225800.040
regulation of cell cycleGO:00517262910.039
purine ribonucleoside monophosphate metabolic processGO:0009167500.039
Yeast
organic substance transportGO:00717022570.039
nucleoside monophosphate metabolic processGO:0009123520.039
Yeast
nucleoside phosphate metabolic processGO:00067531620.039
Yeast
negative regulation of gene expressionGO:00106293870.038
Yeast
microtubule polymerization or depolymerizationGO:0031109390.037
single organism intracellular transportGO:19025822070.037
negative regulation of mitotic sister chromatid separationGO:2000816130.037
negative regulation of mitotic cell cycleGO:00459301090.036
cellular protein localizationGO:00346131600.036
gene silencingGO:00164581380.036
Yeast
dna duplex unwindingGO:0032508160.035
sex differentiationGO:0007548810.035
regulation of triglyceride catabolic processGO:001089610.035
mitotic dna integrity checkpointGO:0044774750.035
ribonucleoside monophosphate metabolic processGO:0009161510.035
Yeast
cell cycle comprising mitosis without cytokinesisGO:0033301250.035
dna catabolic processGO:0006308160.035
regulation of cellular catabolic processGO:00313291570.035
negative regulation of gene expression epigeneticGO:0045814770.035
Yeast
nucleoside triphosphate catabolic processGO:00091431080.035
Yeast
cell cycle g1 s phase transitionGO:0044843310.034
regulation of nucleotide catabolic processGO:0030811480.034
protein maturationGO:0051604710.034
negative regulation of rna biosynthetic processGO:19026792400.033
Yeast
organic acid metabolic processGO:00060821030.033
positive regulation of molecular functionGO:00440931360.033
cell cycle phase transitionGO:00447701400.033
ribonucleotide metabolic processGO:00092591450.032
Yeast
purine nucleoside triphosphate catabolic processGO:00091461080.032
Yeast
nucleotide metabolic processGO:00091171610.032
Yeast
microtubule organizing center organizationGO:00310231680.031
regulation of cytoskeleton organizationGO:0051493890.031
regulation of small gtpase mediated signal transductionGO:0051056930.030
protein processingGO:0016485680.030
purine containing compound catabolic processGO:00725231120.030
Yeast
ribonucleotide catabolic processGO:00092611090.030
Yeast
development of primary sexual characteristicsGO:0045137500.030
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.030
Yeast
mitotic sister chromatid separationGO:0051306300.029
purine nucleoside monophosphate metabolic processGO:0009126500.028
Yeast
regulation of mitotic cell cycleGO:00073461900.028
gonad developmentGO:0008406500.028
organonitrogen compound catabolic processGO:19015651280.028
Yeast
regulation of nucleotide metabolic processGO:0006140620.027
positive regulation of programmed cell deathGO:0043068620.027
double strand break repair via nonhomologous end joiningGO:000630350.027
mitotic dna damage checkpointGO:0044773740.027
microtubule anchoringGO:0034453110.026
ribonucleoside triphosphate metabolic processGO:00091991190.026
Yeast
dna damage checkpointGO:0000077780.026
organophosphate metabolic processGO:00196371950.025
Yeast
macromolecule catabolic processGO:00090571610.025
organelle assemblyGO:00709251980.025
negative regulation of cell cycleGO:00457861160.024
oxoacid metabolic processGO:00434361030.024
regulation of proteolysisGO:0030162870.024
muscle organ developmentGO:00075171270.024
regulation of phosphorus metabolic processGO:00511742100.024
localization of cellGO:00516742570.023
ribonucleoside catabolic processGO:00424541120.023
Yeast
larval developmentGO:00021641040.023
meiosis iGO:0007127590.022
organophosphate catabolic processGO:00464341120.022
Yeast
purine ribonucleoside triphosphate catabolic processGO:00092071080.022
Yeast
response to biotic stimulusGO:00096072940.022
negative regulation of cell cycle phase transitionGO:19019881030.022
positive regulation of nitrogen compound metabolic processGO:00511733540.021
Yeast
positive regulation of macromolecule biosynthetic processGO:00105572830.021
Yeast
positive regulation of hydrolase activityGO:0051345780.021
syncytial blastoderm mitotic cell cycleGO:0035186210.021
dendrite developmentGO:00163582040.021
regulation of cell deathGO:00109411730.021
Zebrafish
dna integrity checkpointGO:0031570810.020
protein catabolic processGO:00301631010.019
positive regulation of response to stimulusGO:00485843230.019
purine ribonucleoside monophosphate catabolic processGO:0009169380.019
Yeast
regulation of purine nucleotide metabolic processGO:1900542620.019
intracellular protein transportGO:00068861040.019
pole cell migrationGO:0007280130.019
purine nucleoside monophosphate catabolic processGO:0009128380.019
Yeast
endocytosisGO:00068973100.019
regulation of dna replicationGO:0006275130.018
Yeast
positive regulation of cellular catabolic processGO:0031331950.018
nucleoside phosphate catabolic processGO:19012921100.018
Yeast
positive regulation of phosphate metabolic processGO:00459371390.018
negative regulation of cellular biosynthetic processGO:00313272770.018
Yeast
protein localization to organelleGO:0033365820.018
response to oxygen containing compoundGO:19017002000.018
cellular protein catabolic processGO:0044257830.018
mitotic sister chromatid segregationGO:0000070870.018
cellular macromolecule catabolic processGO:00442651360.017
metaphase anaphase transition of cell cycleGO:0044784280.017
muscle structure developmentGO:00610612240.016
carbohydrate derivative catabolic processGO:19011361180.016
Yeast
spermatogenesisGO:00072832000.016
actin filament based processGO:00300292200.016
regulation of cellular component biogenesisGO:00440872010.016
cellular protein modification processGO:00064644380.016
vesicle mediated transportGO:00161923810.015
atp catabolic processGO:0006200380.015
Yeast
negative regulation of macromolecule biosynthetic processGO:00105582700.015
Yeast
regulation of localizationGO:00328792750.015
double strand break repair via synthesis dependent strand annealingGO:004500360.015
snrna metabolic processGO:0016073140.015
memoryGO:0007613940.014
regulation of cellular protein metabolic processGO:00322682430.014
nucleotide catabolic processGO:00091661090.014
Yeast
cytokinesisGO:0000910900.014
meiotic cell cycle processGO:19030461320.014
negative regulation of nucleotide metabolic processGO:004598040.014
regulation of purine nucleotide catabolic processGO:0033121480.014
g1 s transition of mitotic cell cycleGO:0000082310.014
negative regulation of catabolic processGO:0009895360.013
ubiquitin dependent protein catabolic processGO:0006511780.013
negative regulation of sister chromatid segregationGO:0033046130.013
response to woundingGO:0009611940.013
protein polymerizationGO:0051258420.013
cell proliferationGO:00082832990.013
negative regulation of rna metabolic processGO:00512532510.013
Yeast
regulation of ras gtpase activityGO:0032318380.013
cytoplasmic transportGO:00164821300.013
response to other organismGO:00517072930.012
genitalia developmentGO:0048806260.012
regulation of multicellular organismal developmentGO:20000264140.012
cell cell signaling involved in cell fate commitmentGO:00451682100.012
positive regulation of phosphorus metabolic processGO:00105621390.012
protein importGO:0017038550.012
protein ubiquitinationGO:0016567700.012
regulation of gene expression epigeneticGO:00400291280.012
Yeast
mitotic spindle checkpointGO:0071174110.012
body morphogenesisGO:001017120.012
negative regulation of proteasomal protein catabolic processGO:1901799160.012
regulation of anatomical structure morphogenesisGO:00226032420.011
epithelial cell differentiationGO:00308553220.011
response to endogenous stimulusGO:00097191190.011
multicellular organismal agingGO:00102591400.011
regulation of chromosome organizationGO:0033044640.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
Yeast
dna double strand break processingGO:000072930.011
positive regulation of developmental processGO:00510941430.011
regulation of ras protein signal transductionGO:0046578930.011
regulation of mitotic sister chromatid segregationGO:0033047280.011
modification dependent protein catabolic processGO:0019941780.011
metaphase anaphase transition of mitotic cell cycleGO:0007091280.011
negative regulation of cellular catabolic processGO:0031330340.011
regulation of mitotic spindle organizationGO:006023690.010
photoreceptor cell differentiationGO:00465301700.010
regulation of nucleoside metabolic processGO:0009118500.010
positive regulation of mitotic cell cycleGO:0045931340.010
establishment of spindle orientationGO:0051294180.010
positive regulation of catabolic processGO:00098961050.010
negative regulation of cellular component organizationGO:00511291080.010

Mcm5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.031
organ system cancerDOID:005068600.031
disease of cellular proliferationDOID:1456600.031