Drosophila melanogaster

101 known processes

PGRP-SA (Dmel_CG11709)

Peptidoglycan recognition protein SA

(Aliases: CG11709,seml,SEMMELWEIS,Dm PGRP-SA,BcDNA:AT30827,Dmel\CG11709,SA)

PGRP-SA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281631.000
defense response to gram positive bacteriumGO:0050830410.984
negative regulation of peptidoglycan recognition protein signaling pathwayGO:006106030.984
Fly
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0006964120.972
Fly
pattern recognition receptor signaling pathwayGO:000222120.970
Fly
immune responseGO:00069552460.966
antibacterial humoral responseGO:0019731440.952
regulation of defense responseGO:00313471020.951
defense responseGO:00069523000.951
immune system processGO:00023763470.946
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000696530.943
immune response activating signal transductionGO:000275720.937
Fly
positive regulation of antibacterial peptide productionGO:0002803200.930
antifungal humoral responseGO:0019732120.929
immune response regulating signaling pathwayGO:000276420.928
Fly
defense response to bacteriumGO:00427421780.923
innate immune response activating signal transductionGO:000275820.918
Fly
humoral immune responseGO:00069591170.914
defense response to other organismGO:00985422250.910
biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281530.910
defense response to fungusGO:0050832480.907
innate immune responseGO:00450871440.904
Fly
regulation of melanization defense responseGO:003500760.903
Fly
peptidoglycan catabolic processGO:000925330.889
Fly
regulation of defense response to bacteriumGO:1900424300.881
positive regulation of antimicrobial peptide productionGO:0002225280.881
negative regulation of defense response to bacteriumGO:190042570.878
Fly
response to fungusGO:0009620500.869
glycosaminoglycan catabolic processGO:000602730.864
Fly
response to external biotic stimulusGO:00432072930.858
activation of innate immune responseGO:000221840.848
Fly
peptidoglycan recognition protein signaling pathwayGO:0061057160.845
Fly
defense response to virusGO:0051607230.838
Fly
antimicrobial humoral responseGO:0019730990.833
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.822
biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002812140.822
Fly
regulation of antimicrobial peptide biosynthetic processGO:0002805380.821
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.801
Fly
response to biotic stimulusGO:00096072940.801
production of molecular mediator of immune responseGO:0002440460.799
melanin metabolic processGO:0006582470.796
Fly
positive regulation of defense response to bacteriumGO:1900426230.787
positive regulation of humoral immune responseGO:0002922280.786
antibacterial peptide productionGO:0002778220.785
positive regulation of antimicrobial humoral responseGO:0002760280.777
regulation of secondary metabolic processGO:004345570.772
Fly
antimicrobial peptide productionGO:0002775460.767
regulation of antibacterial peptide biosynthetic processGO:0002808220.748
antibacterial peptide biosynthetic processGO:0002780220.748
regulation of immune responseGO:00507761180.728
regulation of immune system processGO:00026821760.689
peptide metabolic processGO:0006518800.685
regulation of innate immune responseGO:0045088710.680
Fly
melanization defense responseGO:0035006450.676
Fly
cellular amide metabolic processGO:0043603800.675
glycosaminoglycan metabolic processGO:0030203110.650
Fly
regulation of peptidoglycan recognition protein signaling pathwayGO:006105840.644
Fly
positive regulation of response to biotic stimulusGO:0002833310.635
amide biosynthetic processGO:0043604420.634
positive regulation of cellular amide metabolic processGO:0034250260.632
positive regulation of immune responseGO:0050778630.619
defense response to gram negative bacteriumGO:0050829940.618
Fly
regulation of response to biotic stimulusGO:0002831630.614
response to other organismGO:00517072930.613
regulation of antibacterial peptide productionGO:0002786220.610
peptidoglycan metabolic processGO:000027030.608
Fly
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.595
response to bacteriumGO:00096171980.586
regulation of multi organism processGO:00439001310.577
regulation of humoral immune responseGO:0002920510.565
positive regulation of defense responseGO:0031349590.552
antimicrobial peptide biosynthetic processGO:0002777380.547
regulation of antimicrobial peptide productionGO:0002784440.535
immune effector processGO:0002252980.515
positive regulation of production of molecular mediator of immune responseGO:0002702280.503
positive regulation of multi organism processGO:0043902400.502
regulation of cellular amide metabolic processGO:0034248390.496
regulation of antimicrobial humoral responseGO:0002759500.493
positive regulation of response to external stimulusGO:0032103440.472
aminoglycan metabolic processGO:0006022180.465
Fly
regulation of response to external stimulusGO:00321011150.460
aminoglycan catabolic processGO:000602660.446
Fly
peptide biosynthetic processGO:0043043420.415
regulation of response to stressGO:00801342000.398
regulation of production of molecular mediator of immune responseGO:0002700440.398
response to peptidoglycanGO:003249420.372
hemolymph coagulationGO:0042381100.337
positive regulation of nitrogen compound metabolic processGO:00511733540.333
organonitrogen compound metabolic processGO:19015643180.331
negative regulation of stress activated protein kinase signaling cascadeGO:0070303200.303
Fly
toll signaling pathwayGO:0008063250.300
positive regulation of response to stimulusGO:00485843230.299
negative regulation of immune system processGO:0002683500.289
Fly
positive regulation of melanization defense responseGO:003500810.273
positive regulation of immune system processGO:0002684680.269
secondary metabolic processGO:0019748750.247
Fly
response to virusGO:0009615280.246
Fly
positive regulation of immune effector processGO:0002699280.238
negative regulation of cell communicationGO:00106482230.229
Fly
negative regulation of signal transductionGO:00099682060.193
Fly
negative regulation of cellular metabolic processGO:00313243820.183
Fly
phosphorylationGO:00163102940.181
Fly
phenol containing compound metabolic processGO:0018958570.180
Fly
dorsal ventral axis specificationGO:0009950660.176
organic hydroxy compound metabolic processGO:1901615830.173
Fly
negative regulation of defense responseGO:0031348350.169
Fly
carbohydrate derivative catabolic processGO:19011361180.164
Fly
negative regulation of response to external stimulusGO:0032102220.162
Fly
positive regulation of cellular biosynthetic processGO:00313283160.154
zymogen activationGO:0031638200.152
positive regulation of biosynthetic processGO:00098913160.152
organonitrogen compound biosynthetic processGO:19015661170.142
carbohydrate derivative metabolic processGO:19011352170.139
Fly
pigment metabolic processGO:0042440840.133
Fly
response to woundingGO:0009611940.129
regulation of immune effector processGO:0002697520.126
negative regulation of signalingGO:00230572190.124
Fly
lipopolysaccharide mediated signaling pathwayGO:003166310.116
Fly
activation of immune responseGO:000225350.113
Fly
axis specificationGO:00097981670.112
intracellular signal transductionGO:00355563000.105
Fly
cellular response to lipopolysaccharideGO:007122230.104
Fly
positive regulation of innate immune responseGO:0045089380.104
Fly
jnk cascadeGO:0007254500.102
Fly
stress activated mapk cascadeGO:0051403520.100
Fly
regionalizationGO:00030024160.096
negative regulation of response to stimulusGO:00485852580.095
Fly
protein maturationGO:0051604710.093
negative regulation of innate immune responseGO:0045824300.093
Fly
organonitrogen compound catabolic processGO:19015651280.090
Fly
wound healingGO:0042060750.089
regulation of phosphorylationGO:00423251470.085
Fly
negative regulation of phosphorylationGO:0042326350.082
Fly
dorsal ventral pattern formationGO:00099531330.071
regulation of jnk cascadeGO:0046328400.071
Fly
cellular response to lipidGO:0071396200.070
Fly
response to lipopolysaccharideGO:003249640.069
Fly
macromolecule catabolic processGO:00090571610.069
Fly
vesicle mediated transportGO:00161923810.066
regulation of stress activated mapk cascadeGO:0032872410.066
Fly
regulation of phosphorus metabolic processGO:00511742100.064
Fly
cellular response to molecule of bacterial originGO:007121930.061
Fly
stress activated protein kinase signaling cascadeGO:0031098550.060
Fly
regulation of intracellular signal transductionGO:19025312360.058
Fly
appendage morphogenesisGO:00351073970.058
regulation of mapk cascadeGO:0043408920.058
Fly
regulation of toll signaling pathwayGO:0008592170.057
mapk cascadeGO:00001651070.056
Fly
cytolysisGO:001983510.056
post embryonic appendage morphogenesisGO:00351203850.052
catabolic processGO:00090564090.051
Fly
negative regulation of intracellular signal transductionGO:1902532570.051
Fly
endocytosisGO:00068973100.049
positive regulation of signalingGO:00230562430.048
negative regulation of mapk cascadeGO:0043409230.048
Fly
imaginal disc derived wing morphogenesisGO:00074763370.047
agingGO:00075681430.046
Fly
cellular response to biotic stimulusGO:007121640.046
Fly
positive regulation of cell communicationGO:00106472500.046
protein processingGO:0016485680.045
imaginal disc derived appendage developmentGO:00487373990.045
regulation of stress activated protein kinase signaling cascadeGO:0070302420.045
Fly
positive regulation of signal transductionGO:00099672230.044
small molecule metabolic processGO:00442813050.043
wing disc morphogenesisGO:00074723440.043
developmental growthGO:00485892800.042
response to molecule of bacterial originGO:000223770.042
negative regulation of phosphate metabolic processGO:0045936450.042
Fly
amino sugar metabolic processGO:0006040100.039
protein modification processGO:00362114380.038
glucosamine containing compound catabolic processGO:190107230.038
phagocytosisGO:00069092150.037
proteolysisGO:00065081920.035
melanotic encapsulation of foreign targetGO:0035011300.035
negative regulation of response to biotic stimulusGO:0002832120.035
Fly
negative regulation of protein metabolic processGO:0051248850.034
appendage developmentGO:00487364010.033
imaginal disc derived appendage morphogenesisGO:00351143950.032
response to nitrogen compoundGO:1901698900.031
organic substance catabolic processGO:19015753080.031
Fly
response to organonitrogen compoundGO:0010243750.031
cellular protein modification processGO:00064644380.029
response to organic substanceGO:00100332840.029
positive regulation of antifungal peptide biosynthetic processGO:000696750.029
cellular response to oxygen containing compoundGO:1901701790.029
Fly
determination of adult lifespanGO:00083401370.029
Fly
regulation of phosphate metabolic processGO:00192202100.028
Fly
organophosphate metabolic processGO:00196371950.027
compound eye developmentGO:00487493070.026
negative regulation of phosphorus metabolic processGO:0010563450.026
Fly
response to oxygen containing compoundGO:19017002000.025
negative regulation of gene expressionGO:00106293870.024
homeostatic processGO:00425921990.024
response to endogenous stimulusGO:00097191190.023
negative regulation of multi organism processGO:0043901290.022
Fly
wnt signaling pathwayGO:0016055980.022
eye developmentGO:00016543230.022
cellular catabolic processGO:00442483720.022
negative regulation of cellular protein metabolic processGO:0032269850.021
body morphogenesisGO:001017120.020
nuclear divisionGO:00002803320.020
regulation of proteolysisGO:0030162870.020
negative regulation of cell differentiationGO:00455961430.020
negative regulation of nitrogen compound metabolic processGO:00511722650.020
positive regulation of cell migrationGO:003033520.020
signal transduction by phosphorylationGO:00230141070.020
Fly
negative regulation of peptide hormone processingGO:006057010.020
single organism catabolic processGO:00447122280.020
growthGO:00400073590.019
cell adhesionGO:00071551360.019
actin filament based processGO:00300292200.019
negative regulation of immune responseGO:0050777390.019
Fly
epithelial cell developmentGO:00020642740.019
response to organophosphorusGO:004668320.018
coagulationGO:0050817100.018
multicellular organismal agingGO:00102591400.018
Fly
aromatic compound catabolic processGO:00194391660.018
regulation of multicellular organismal developmentGO:20000264140.018
regulation of protein metabolic processGO:00512462560.018
segmentationGO:00352822070.017
chemotaxisGO:00069352490.017
regulation of cellular response to stressGO:0080135890.017
Fly
cation homeostasisGO:0055080510.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
morphogenesis of an epitheliumGO:00020092760.017
regulation of molecular functionGO:00650092170.017
cellular response to nutrient levelsGO:0031669620.017
regulation of body fluid levelsGO:0050878140.017
single organism cell adhesionGO:0098602470.016
regulation of cell cycleGO:00517262910.016
chitin catabolic processGO:000603230.016
organic acid metabolic processGO:00060821030.016
connective tissue developmentGO:006144830.016
mitotic spindle organizationGO:00070522200.016
cellular response to chemical stimulusGO:00708871990.016
Fly
epithelium migrationGO:00901321480.015
regulation of growthGO:00400082330.015
oxoacid metabolic processGO:00434361030.015
negative regulation of stress activated mapk cascadeGO:0032873190.015
Fly
retina development in camera type eyeGO:006004140.015
negative regulation of molecular functionGO:0044092510.015
amino sugar catabolic processGO:004634830.015
ameboidal type cell migrationGO:00016671510.015
columnar cuboidal epithelial cell developmentGO:00020662490.015
negative regulation of catalytic activityGO:0043086420.015
cellular amino acid metabolic processGO:0006520610.014
single organismal cell cell adhesionGO:0016337450.014
positive regulation of cellular component organizationGO:00511301560.014
nucleobase containing small molecule metabolic processGO:00550861740.014
organelle fissionGO:00482853400.014
ovarian follicle cell migrationGO:00072971210.014
negative regulation of developmental processGO:00510932010.014
positive regulation of intracellular signal transductionGO:19025331160.014
protein localizationGO:00081042840.014
cellular response to dna damage stimulusGO:00069742230.014
blastoderm segmentationGO:00073501590.014
sensory organ morphogenesisGO:00905962600.014
cellular homeostasisGO:0019725800.013
embryonic pattern specificationGO:00098801740.013
tissue migrationGO:00901301550.013
regulation of protein modification processGO:00313991120.013
protein phosphorylationGO:00064681690.013
gene silencing by rnaGO:0031047570.013
developmental maturationGO:00217001720.013
nucleoside metabolic processGO:00091161270.013
carboxylic acid metabolic processGO:0019752920.012
amine metabolic processGO:0009308120.012
ovarian follicle cell developmentGO:00307072480.012
spindle organizationGO:00070512530.012
response to starvationGO:0042594970.012
cellular ketone metabolic processGO:0042180240.012
cellular response to starvationGO:0009267610.012
cellular amine metabolic processGO:0044106120.012
endomembrane system organizationGO:00102561190.012
response to extracellular stimulusGO:00099911160.012
mitotic nuclear divisionGO:00070672130.012
epithelial cell migrationGO:00106311480.012
forebrain developmentGO:003090020.011
morphogenesis of a polarized epitheliumGO:0001738930.011
organelle assemblyGO:00709251980.011
cellular nitrogen compound catabolic processGO:00442701650.011
response to lipidGO:0033993380.011
Fly
regulation of catabolic processGO:00098941700.011
biological adhesionGO:00226101380.011
detection of chemical stimulusGO:0009593930.011
anatomical structure homeostasisGO:0060249970.011
g protein coupled receptor signaling pathwayGO:00071861360.011
positive regulation of cell motilityGO:200014730.011
salivary gland developmentGO:00074311620.011
regulation of cell cell adhesionGO:0022407210.011
epithelial cell differentiationGO:00308553220.011
organic cyclic compound catabolic processGO:19013611680.011
positive regulation of phosphorus metabolic processGO:00105621390.011
regulation of cell adhesionGO:0030155270.011
regulation of cellular component biogenesisGO:00440872010.011
compound eye morphogenesisGO:00017452490.011
establishment of planar polarityGO:0001736870.011
gland morphogenesisGO:00226121450.011
regulation of cell morphogenesisGO:00226041630.011
respiratory system developmentGO:00605412130.010
chemical homeostasisGO:0048878920.010
jak stat cascadeGO:0007259490.010
glucosamine containing compound metabolic processGO:190107190.010
divalent inorganic cation homeostasisGO:0072507290.010
tissue morphogenesisGO:00487292970.010
positive regulation of antifungal peptide productionGO:000280460.010
actin filament organizationGO:00070151260.010
regulation of antifungal peptide productionGO:000278860.010
macromolecular complex assemblyGO:00650032560.010
open tracheal system developmentGO:00074242040.010
establishment of protein localizationGO:00451841630.010
positive regulation of phosphate metabolic processGO:00459371390.010
neuronal action potentialGO:0019228100.010
positive regulation of nucleobase containing compound metabolic processGO:00459353320.010
camera type eye developmentGO:004301040.010
response to abiotic stimulusGO:00096283410.010
protein complex biogenesisGO:00702712010.010

PGRP-SA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
inherited metabolic disorderDOID:65500.012
disease of metabolismDOID:001466700.012