Drosophila melanogaster

32 known processes

MESK2 (Dmel_CG15669)

Misexpression suppressor of KSR 2

(Aliases: mesk2,Mesk2,CG15668,BcDNA:GH12032,BcDNA:RH10174,CG15669,Dmel\CG15669,BcDNA:LD27504,l(2)01467)

MESK2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of signalingGO:00230572190.572
Mouse
chemosensory behaviorGO:00076351060.533
response to abiotic stimulusGO:00096283410.465
negative regulation of cell communicationGO:00106482230.395
Mouse
endocytosisGO:00068973100.390
vesicle mediated transportGO:00161923810.361
learning or memoryGO:00076111410.356
ion transmembrane transportGO:00342201220.348
locomotory behaviorGO:00076261760.327
response to mechanical stimulusGO:0009612280.268
rhythmic processGO:00485111060.254
cognitionGO:00508901410.234
associative learningGO:0008306650.218
sleepGO:0030431490.217
synaptic transmissionGO:00072682880.209
learningGO:0007612750.187
olfactory learningGO:0008355560.160
phosphorylationGO:00163102940.157
Mouse
olfactory behaviorGO:0042048970.130
rhythmic behaviorGO:0007622760.127
wing disc morphogenesisGO:00074723440.126
regulation of synaptic transmissionGO:0050804690.125
phagocytosisGO:00069092150.118
taxisGO:00423303040.113
response to light stimulusGO:00094161240.112
regulation of circadian rhythmGO:0042752490.111
inter male aggressive behaviorGO:0002121600.110
negative regulation of response to stimulusGO:00485852580.108
Mouse
ion transportGO:00068111450.108
homeostatic processGO:00425921990.107
positive regulation of nitrogen compound metabolic processGO:00511733540.106
inorganic ion transmembrane transportGO:0098660730.103
imaginal disc derived wing morphogenesisGO:00074763370.095
response to external biotic stimulusGO:00432072930.094
protein complex biogenesisGO:00702712010.087
negative regulation of developmental processGO:00510932010.087
regulation of behaviorGO:0050795750.086
circadian sleep wake cycleGO:0042745280.086
organophosphate metabolic processGO:00196371950.085
eye developmentGO:00016543230.084
neurological system processGO:00508773580.082
small molecule metabolic processGO:00442813050.080
positive regulation of cellular biosynthetic processGO:00313283160.080
organonitrogen compound metabolic processGO:19015643180.079
appendage morphogenesisGO:00351073970.077
cell deathGO:00082192790.077
regulation of circadian sleep wake cycleGO:0042749250.076
regulation of multicellular organismal developmentGO:20000264140.074
Rat
programmed cell deathGO:00125012570.074
transcription from rna polymerase ii promoterGO:00063663680.072
regulation of intracellular signal transductionGO:19025312360.070
multi organism behaviorGO:00517051750.069
localization of cellGO:00516742570.068
cellular response to radiationGO:0071478520.068
protein complex assemblyGO:00064612000.067
establishment of localization in cellGO:00516494020.063
single organism behaviorGO:00447083910.061
imaginal disc derived appendage developmentGO:00487373990.060
macromolecular complex assemblyGO:00650032560.060
cellular protein modification processGO:00064644380.059
negative regulation of biosynthetic processGO:00098902770.059
single organism intracellular transportGO:19025822070.059
regulation of immune system processGO:00026821760.058
intracellular signal transductionGO:00355563000.058
cellular response to light stimulusGO:0071482370.058
defense responseGO:00069523000.054
regulation of cell proliferationGO:00421271630.053
Mouse
immune system processGO:00023763470.051
response to other organismGO:00517072930.051
axonogenesisGO:00074092900.051
negative regulation of multicellular organismal processGO:00512411420.050
Mouse
positive regulation of macromolecule metabolic processGO:00106044050.048
response to biotic stimulusGO:00096072940.047
organic substance transportGO:00717022570.045
aggressive behaviorGO:0002118630.045
regulation of localizationGO:00328792750.045
nucleoside phosphate metabolic processGO:00067531620.045
transmembrane transportGO:00550851390.044
deathGO:00162652840.044
cellular catabolic processGO:00442483720.044
post embryonic appendage morphogenesisGO:00351203850.044
nucleotide metabolic processGO:00091171610.044
regulation of cell developmentGO:00602842150.044
Rat
imaginal disc derived appendage morphogenesisGO:00351143950.044
regulation of transportGO:00510491810.043
catabolic processGO:00090564090.043
ribose phosphate metabolic processGO:00196931450.043
defense response to other organismGO:00985422250.041
detection of light stimulusGO:0009583580.041
protein modification processGO:00362114380.040
single organism catabolic processGO:00447122280.040
regulation of catalytic activityGO:00507901850.040
positive regulation of response to stimulusGO:00485843230.039
kidney developmentGO:000182230.039
negative regulation of gene expressionGO:00106293870.039
axon guidanceGO:00074112330.039
negative regulation of cellular component organizationGO:00511291080.038
immune responseGO:00069552460.037
regulation of cell cycleGO:00517262910.036
appendage developmentGO:00487364010.036
nucleoside triphosphate metabolic processGO:00091411200.036
response to drugGO:0042493170.035
regulation of molecular functionGO:00650092170.035
intracellular transportGO:00469072280.034
positive regulation of nucleobase containing compound metabolic processGO:00459353320.034
negative regulation of cellular metabolic processGO:00313243820.034
Mouse
negative regulation of programmed cell deathGO:0043069720.034
cell proliferationGO:00082832990.033
Mouse
regulation of cellular component biogenesisGO:00440872010.033
purine ribonucleotide metabolic processGO:00091501450.033
tissue morphogenesisGO:00487292970.033
response to radiationGO:00093141550.032
developmental maturationGO:00217001720.032
regulation of cell differentiationGO:00455953020.032
Rat
anion transportGO:0006820410.031
positive regulation of gene expressionGO:00106282900.031
regionalizationGO:00030024160.031
ribonucleotide metabolic processGO:00092591450.031
morphogenesis of an epitheliumGO:00020092760.030
positive regulation of cell communicationGO:00106472500.030
enzyme linked receptor protein signaling pathwayGO:00071671790.030
acetylcholine metabolic processGO:000829120.029
regulation of protein metabolic processGO:00512462560.029
camera type eye developmentGO:004301040.029
apoptotic processGO:00069151590.028
chloride transportGO:0006821100.028
single organism biosynthetic processGO:00447112060.028
cellular response to chemical stimulusGO:00708871990.028
response to organic substanceGO:00100332840.027
purine nucleotide catabolic processGO:00061951090.027
cell maturationGO:00484691440.027
negative regulation of cellular biosynthetic processGO:00313272770.027
mapk cascadeGO:00001651070.027
Mouse
axon developmentGO:00615642970.027
positive regulation of biosynthetic processGO:00098913160.027
regulation of transcription from rna polymerase ii promoterGO:00063573780.027
protein phosphorylationGO:00064681690.027
cell migrationGO:00164772380.026
developmental programmed cell deathGO:00106231380.026
ras protein signal transductionGO:0007265880.026
growthGO:00400073590.026
negative regulation of protein metabolic processGO:0051248850.025
positive regulation of phosphate metabolic processGO:00459371390.025
regulation of ras protein signal transductionGO:0046578930.025
establishment or maintenance of cell polarityGO:00071631670.025
regulation of phosphorus metabolic processGO:00511742100.025
Mouse
protein transportGO:00150311550.025
response to temperature stimulusGO:00092661060.024
glycosyl compound metabolic processGO:19016571270.024
regulation of programmed cell deathGO:00430671520.024
nucleobase containing small molecule metabolic processGO:00550861740.024
tube developmentGO:00352952440.024
cation transportGO:00068121100.024
metal ion transportGO:0030001740.024
chemical homeostasisGO:0048878920.023
purine containing compound metabolic processGO:00725211550.023
neuromuscular junction developmentGO:00075281490.023
proteolysisGO:00065081920.023
cell motilityGO:00488702510.023
negative regulation of signal transductionGO:00099682060.023
Mouse
cellular response to abiotic stimulusGO:0071214580.023
negative regulation of cell deathGO:0060548810.023
anion transmembrane transportGO:0098656260.023
regulation of olfactory learningGO:009032880.023
cytoplasmic transportGO:00164821300.022
negative regulation of immune system processGO:0002683500.022
positive regulation of macromolecule biosynthetic processGO:00105572830.022
phototransductionGO:0007602520.022
negative regulation of nucleic acid templated transcriptionGO:19035072400.022
regulation of cellular ketone metabolic processGO:001056530.022
dendrite developmentGO:00163582040.022
negative regulation of synaptic transmissionGO:0050805120.022
organic substance catabolic processGO:19015753080.022
regulation of i kappab kinase nf kappab signalingGO:004312220.021
protein complex disassemblyGO:0043241360.021
negative regulation of nitrogen compound metabolic processGO:00511722650.021
small gtpase mediated signal transductionGO:0007264880.021
response to bacteriumGO:00096171980.021
chemotaxisGO:00069352490.021
regulation of defense responseGO:00313471020.021
regulation of mitotic cell cycleGO:00073461900.021
regulation of phosphate metabolic processGO:00192202100.021
Mouse
male mating behaviorGO:0060179700.021
cellular nitrogen compound catabolic processGO:00442701650.021
adult behaviorGO:00305341370.020
organelle localizationGO:00516401480.020
sensory organ morphogenesisGO:00905962600.020
salivary gland morphogenesisGO:00074351450.020
negative regulation of nervous system developmentGO:0051961920.020
carbohydrate derivative metabolic processGO:19011352170.020
positive regulation of signalingGO:00230562430.020
salivary gland developmentGO:00074311620.020
cellular macromolecule catabolic processGO:00442651360.020
imaginal disc growthGO:0007446370.020
aromatic compound catabolic processGO:00194391660.020
organic hydroxy compound metabolic processGO:1901615830.020
gland morphogenesisGO:00226121450.019
axis specificationGO:00097981670.019
regulation of phosphorylationGO:00423251470.019
Mouse
purine ribonucleotide catabolic processGO:00091541090.019
negative regulation of macromolecule biosynthetic processGO:00105582700.019
negative regulation of nucleobase containing compound metabolic processGO:00459342610.019
notch signaling pathwayGO:00072191200.019
response to lipopolysaccharideGO:003249640.019
negative regulation of rna biosynthetic processGO:19026792400.019
eye morphogenesisGO:00485922600.019
oocyte dorsal ventral axis specificationGO:0007310340.019
regulation of multi organism processGO:00439001310.019
positive regulation of molecular functionGO:00440931360.019
epithelial cell differentiationGO:00308553220.019
morphogenesis of a branching structureGO:0001763450.018
positive regulation of signal transductionGO:00099672230.018
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.018
positive regulation of catalytic activityGO:00430851180.018
purine ribonucleoside triphosphate metabolic processGO:00092051190.018
nitrogen compound transportGO:0071705850.018
regulation of organelle organizationGO:00330431960.018
actin cytoskeleton organizationGO:00300362060.018
compound eye developmentGO:00487493070.018
positive regulation of rna biosynthetic processGO:19026802660.017
regulation of anatomical structure morphogenesisGO:00226032420.017
regulation of nervous system developmentGO:00519602480.017
Rat
signal transduction by phosphorylationGO:00230141070.017
Mouse
compound eye morphogenesisGO:00017452490.017
amine metabolic processGO:0009308120.017
negative regulation of transcription dna templatedGO:00458922370.017
negative regulation of cellular protein metabolic processGO:0032269850.017
rna processingGO:00063961470.017
nucleobase containing compound catabolic processGO:00346551650.017
response to alcoholGO:0097305950.017
mitotic cell cycle phase transitionGO:00447721380.017
multicellular organismal agingGO:00102591400.017
forebrain developmentGO:003090020.016
detection of stimulusGO:00516061560.016
regulation of synapse structure and activityGO:00508031280.016
nucleotide catabolic processGO:00091661090.016
purine ribonucleoside catabolic processGO:00461301120.016
regulation of cellular localizationGO:00603411360.016
ribonucleoside metabolic processGO:00091191270.016
regulation of cellular amine metabolic processGO:003323830.016
establishment of protein localizationGO:00451841630.016
heterocycle catabolic processGO:00467001660.016
neuron projection guidanceGO:00974852410.016
embryonic development via the syncytial blastodermGO:00017001480.016
nucleoside phosphate catabolic processGO:19012921100.016
anatomical structure homeostasisGO:0060249970.016
nucleoside metabolic processGO:00091161270.015
negative regulation of rna metabolic processGO:00512532510.015
cellular ketone metabolic processGO:0042180240.015
protein catabolic processGO:00301631010.015
adult locomotory behaviorGO:0008344760.015
regulation of cellular amino acid metabolic processGO:000652100.015
tissue deathGO:00162711020.015
neural precursor cell proliferationGO:0061351750.015
positive regulation of exocytosisGO:004592140.015
connective tissue developmentGO:006144830.015
dendrite morphogenesisGO:00488131990.015
regulation of neurological system processGO:003164480.015
regulation of response to stressGO:00801342000.015
organic acid metabolic processGO:00060821030.015
macromolecule catabolic processGO:00090571610.015
cellular response to organic substanceGO:00713101320.015
regulation of cell deathGO:00109411730.015
ameboidal type cell migrationGO:00016671510.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
cell cycle phase transitionGO:00447701400.014
positive regulation of intracellular signal transductionGO:19025331160.014
innate immune responseGO:00450871440.014
detection of abiotic stimulusGO:0009582660.014
nuclear transportGO:0051169720.014
dna metabolic processGO:00062592270.014
regulation of reproductive processGO:2000241540.014
respiratory system developmentGO:00605412130.014
positive regulation of transcription dna templatedGO:00458932660.014
regulation of rna splicingGO:0043484690.014
posttranscriptional regulation of gene expressionGO:00106081450.014
dorsal ventral pattern formationGO:00099531330.014
regulation of apoptotic processGO:00429811300.014
body morphogenesisGO:001017120.014
response to nutrient levelsGO:00316671140.014
protein processingGO:0016485680.014
single organism cellular localizationGO:19025801800.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
synapse organizationGO:00508081960.013
tissue migrationGO:00901301550.013
cellular protein catabolic processGO:0044257830.013
positive regulation of protein metabolic processGO:00512471280.013
purine nucleoside metabolic processGO:00422781270.013
regulation of anatomical structure sizeGO:00900661630.013
response to decreased oxygen levelsGO:0036293580.013
retina development in camera type eyeGO:006004140.013
regulation of notch signaling pathwayGO:00085931000.013
intracellular protein transportGO:00068861040.013
exocrine system developmentGO:00352721620.013
wing disc pattern formationGO:0035222660.013
camera type eye morphogenesisGO:004859320.013
regulation of cellular protein metabolic processGO:00322682430.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
positive regulation of catabolic processGO:00098961050.013
regulation of secretion by cellGO:1903530390.013
regulation of organ morphogenesisGO:2000027780.013
positive regulation of phosphorus metabolic processGO:00105621390.013
epithelium migrationGO:00901321480.013
regulation of small gtpase mediated signal transductionGO:0051056930.013
negative regulation of cell differentiationGO:00455961430.013
signal releaseGO:0023061490.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
regulation of purine nucleotide metabolic processGO:1900542620.013
erbb signaling pathwayGO:0038127580.013
developmental growthGO:00485892800.013
ribonucleotide catabolic processGO:00092611090.013
oxoacid metabolic processGO:00434361030.013
regulation of innate immune responseGO:0045088710.012
tube morphogenesisGO:00352391910.012
positive regulation of developmental processGO:00510941430.012
Rat
oocyte differentiationGO:00099941450.012
spindle organizationGO:00070512530.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
organonitrogen compound biosynthetic processGO:19015661170.012
reproductive system developmentGO:0061458740.012
regulation of response to external stimulusGO:00321011150.012
regulation of protein modification processGO:00313991120.012
protein localizationGO:00081042840.012
protein modification by small protein conjugationGO:0032446790.012
regulation of nucleotide metabolic processGO:0006140620.012
branching morphogenesis of an epithelial tubeGO:0048754450.012
negative regulation of apoptotic processGO:0043066630.012
defense response to bacteriumGO:00427421780.012
regulation of vesicle mediated transportGO:0060627590.012
negative regulation of organelle organizationGO:0010639560.012
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.012
cell cycle arrestGO:000705040.012
smoothened signaling pathwayGO:0007224490.012
nucleoside triphosphate catabolic processGO:00091431080.012
microtubule polymerization or depolymerizationGO:0031109390.012
positive regulation of multicellular organismal processGO:00512401430.012
Rat
response to oxygen levelsGO:0070482590.012
secretion by cellGO:00329401010.012
regulation of hydrolase activityGO:0051336970.012
imaginal disc derived wing vein morphogenesisGO:0008586440.012
actin filament based processGO:00300292200.012
purine nucleoside catabolic processGO:00061521120.012
regulation of growthGO:00400082330.011
neuromuscular synaptic transmissionGO:0007274670.011
nucleocytoplasmic transportGO:0006913720.011
embryonic morphogenesisGO:00485982060.011
organophosphate catabolic processGO:00464341120.011
rrna processingGO:000636430.011
epidermal growth factor receptor signaling pathwayGO:0007173580.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
cellular amino acid metabolic processGO:0006520610.011
gland developmentGO:00487321910.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
nucleoside catabolic processGO:00091641120.011
g protein coupled receptor signaling pathwayGO:00071861360.011
negative regulation of phosphate metabolic processGO:0045936450.011
Mouse
chromatin modificationGO:00165681470.011
endomembrane system organizationGO:00102561190.011
regulation of protein localizationGO:0032880760.011
nephron developmentGO:007200630.011
cellular carbohydrate metabolic processGO:0044262220.011
secretionGO:00469031090.011
purine nucleotide metabolic processGO:00061631460.011
negative regulation of neurogenesisGO:0050768530.011
regulation of protein phosphorylationGO:0001932640.011
cranial nerve developmentGO:002154510.011
myotube cell developmentGO:001490430.011
synaptic growth at neuromuscular junctionGO:00511241190.011
cellular homeostasisGO:0019725800.011
cell cell signaling involved in cell fate commitmentGO:00451682100.011
macromolecular complex disassemblyGO:0032984370.011
organelle fissionGO:00482853400.011
skin developmentGO:0043588650.011
muscle structure developmentGO:00610612240.011
cellular amine metabolic processGO:0044106120.011
skeletal muscle fiber developmentGO:004874130.011
regulation of wnt signaling pathwayGO:0030111680.011
nucleus organizationGO:0006997450.011
actin polymerization or depolymerizationGO:0008154310.010
response to extracellular stimulusGO:00099911160.010
organonitrogen compound catabolic processGO:19015651280.010
detection of external stimulusGO:0009581660.010
response to woundingGO:0009611940.010
salivary gland cell autophagic cell deathGO:0035071830.010
regulation of locomotionGO:0040012420.010
positive regulation of transportGO:0051050920.010
intrinsic apoptotic signaling pathwayGO:0097193160.010
establishment of organelle localizationGO:00516561220.010
negative regulation of phosphorus metabolic processGO:0010563450.010
Mouse
neuroblast proliferationGO:0007405740.010
cyclic nucleotide metabolic processGO:0009187280.010
neuronal stem cell divisionGO:0036445350.010
gtp metabolic processGO:0046039720.010
establishment of planar polarityGO:0001736870.010
dna integrity checkpointGO:0031570810.010
negative regulation of catalytic activityGO:0043086420.010
ovarian follicle cell developmentGO:00307072480.010

MESK2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
musculoskeletal system diseaseDOID:1700.019
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.014
bone diseaseDOID:008000100.013
connective tissue diseaseDOID:6500.013
cardiovascular system diseaseDOID:128700.011
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.010