Drosophila melanogaster

44 known processes

spd-2 (Dmel_CG17286)

spindle defective 2

(Aliases: DSpd-2,Dmel\CG17286,spd2,SPD-2,Spd-2,BcDNA:LD24702,DSPD-2,CG17286-PA,Dspd-2,anon-73Ba,D-Spd2,CG17286,DSpd2)

spd-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
centrosome separationGO:0051299200.673
organelle localizationGO:00516401480.642
single fertilizationGO:0007338240.628
organelle assemblyGO:00709251980.625
male meiosisGO:0007140520.523
male gamete generationGO:00482322010.487
protein complex assemblyGO:00064612000.447
macromolecular complex assemblyGO:00650032560.399
centrosome cycleGO:00070981370.380
centrosome organizationGO:00512971630.372
nuclear divisionGO:00002803320.363
spindle organizationGO:00070512530.336
centrosome duplicationGO:00512981210.324
protein complex biogenesisGO:00702712010.305
fertilizationGO:0009566260.295
spindle assembly involved in meiosisGO:0090306200.273
meiotic nuclear divisionGO:00071261510.263
maintenance of location in cellGO:0051651280.258
cellular protein localizationGO:00346131600.225
centriole replicationGO:0007099240.210
establishment of organelle localizationGO:00516561220.205
single organism cellular localizationGO:19025801800.203
centriole assemblyGO:0098534240.196
centriole centriole cohesionGO:001045750.183
spindle assemblyGO:0051225800.167
organelle fissionGO:00482853400.162
cellular macromolecule localizationGO:00707272200.160
spindle assembly involved in mitosisGO:0090307500.159
mitotic spindle stabilizationGO:004314860.151
nucleus organizationGO:0006997450.149
spermatogenesisGO:00072832000.139
dna packagingGO:0006323910.123
establishment of localization in cellGO:00516494020.118
spindle midzone assemblyGO:005125540.118
regulation of cytoskeleton organizationGO:0051493890.116
spindle elongationGO:0051231830.113
establishment of spindle orientationGO:0051294180.112
microtubule organizing center organizationGO:00310231680.107
dna metabolic processGO:00062592270.105
cell deathGO:00082192790.105
positive regulation of response to stimulusGO:00485843230.099
mitotic spindle midzone assemblyGO:005125610.099
dna conformation changeGO:00711031050.099
regulation of mitotic spindle organizationGO:006023690.091
mitotic cell cycle embryonicGO:0045448380.090
spindle assembly involved in female meiosisGO:0007056140.087
cytokinesisGO:0000910900.086
maintenance of protein location in cellGO:0032507260.086
cellular component assembly involved in morphogenesisGO:00109271510.080
negative regulation of protein depolymerizationGO:1901880230.080
asymmetric cell divisionGO:0008356370.074
mitotic cytokinesisGO:0000281500.074
negative regulation of cellular metabolic processGO:00313243820.073
regulation of protein depolymerizationGO:1901879270.070
organophosphate metabolic processGO:00196371950.069
negative regulation of rna metabolic processGO:00512532510.066
catabolic processGO:00090564090.066
mitotic spindle elongationGO:0000022810.065
positive regulation of cellular protein metabolic processGO:00322701180.063
regulation of cell differentiationGO:00455953020.063
protein localization to organelleGO:0033365820.061
negative regulation of gene expressionGO:00106293870.061
deathGO:00162652840.061
regulation of cellular localizationGO:00603411360.060
mitotic spindle organizationGO:00070522200.058
regulation of protein complex disassemblyGO:0043244290.057
cellular protein complex assemblyGO:0043623710.057
chromosome condensationGO:0030261410.057
cytoskeleton dependent cytokinesisGO:0061640810.053
regulation of mitotic cell cycleGO:00073461900.051
protein localizationGO:00081042840.051
attachment of spindle microtubules to kinetochoreGO:000860850.050
cellular macromolecular complex assemblyGO:00346221530.049
microtubule anchoringGO:0034453110.049
negative regulation of microtubule depolymerizationGO:0007026210.049
regulation of microtubule cytoskeleton organizationGO:0070507410.047
mitotic centrosome separationGO:000710080.046
transpositionGO:0032196130.045
establishment or maintenance of cell polarityGO:00071631670.045
cell motilityGO:00488702510.044
negative regulation of macromolecule biosynthetic processGO:00105582700.044
stem cell divisionGO:0017145690.044
chromosome organizationGO:00512763600.043
cell divisionGO:00513012480.043
negative regulation of cell deathGO:0060548810.042
regulation of cell cycleGO:00517262910.042
cell maturationGO:00484691440.042
cytokinetic processGO:0032506270.041
organonitrogen compound metabolic processGO:19015643180.041
regulation of catalytic activityGO:00507901850.040
negative regulation of response to stimulusGO:00485852580.039
neural precursor cell proliferationGO:0061351750.039
small molecule metabolic processGO:00442813050.039
negative regulation of signalingGO:00230572190.038
regulation of molecular functionGO:00650092170.038
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.037
regulation of spindle organizationGO:0090224170.037
body morphogenesisGO:001017120.036
cell migrationGO:00164772380.036
cellular nitrogen compound catabolic processGO:00442701650.035
ribonucleoside triphosphate metabolic processGO:00091991190.034
positive regulation of cell communicationGO:00106472500.034
microtubule cytoskeleton organization involved in mitosisGO:1902850520.034
cell proliferationGO:00082832990.034
actin filament based processGO:00300292200.034
regulation of microtubule depolymerizationGO:0031114240.034
rna 3 end processingGO:0031123450.033
male meiosis cytokinesisGO:0007112260.033
meiotic cell cycle processGO:19030461320.031
somatic stem cell divisionGO:0048103370.030
small gtpase mediated signal transductionGO:0007264880.030
meiotic cell cycleGO:00513211710.030
localization of cellGO:00516742570.030
oocyte developmentGO:00485991240.030
protein dna complex assemblyGO:0065004630.030
regulation of phosphorus metabolic processGO:00511742100.030
aromatic compound catabolic processGO:00194391660.030
negative regulation of biosynthetic processGO:00098902770.029
protein modification processGO:00362114380.029
organic substance transportGO:00717022570.028
negative regulation of nucleotide metabolic processGO:004598040.028
regulation of multicellular organismal developmentGO:20000264140.028
vesicle mediated transportGO:00161923810.028
synaptic transmissionGO:00072682880.027
positive regulation of nucleobase containing compound metabolic processGO:00459353320.027
meiosis iGO:0007127590.027
positive regulation of phosphorus metabolic processGO:00105621390.027
actin cytoskeleton organizationGO:00300362060.027
regulation of nervous system developmentGO:00519602480.027
chromatin organizationGO:00063252070.027
positive regulation of cellular component biogenesisGO:0044089800.027
negative regulation of programmed cell deathGO:0043069720.027
single organism intracellular transportGO:19025822070.026
negative regulation of cellular component organizationGO:00511291080.026
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.026
organic substance catabolic processGO:19015753080.026
positive regulation of phosphate metabolic processGO:00459371390.026
cilium organizationGO:0044782410.025
negative regulation of nitrogen compound metabolic processGO:00511722650.025
endomembrane system organizationGO:00102561190.025
transcription from rna polymerase ii promoterGO:00063663680.025
intracellular signal transductionGO:00355563000.025
maintenance of locationGO:0051235730.024
negative regulation of apoptotic processGO:0043066630.024
protein import into nucleusGO:0006606510.024
programmed cell deathGO:00125012570.024
dna geometric changeGO:0032392160.024
cell cycle comprising mitosis without cytokinesisGO:0033301250.024
embryo development ending in birth or egg hatchingGO:00097921520.024
chromatin modificationGO:00165681470.023
negative regulation of nucleobase containing compound metabolic processGO:00459342610.023
establishment of nucleus localizationGO:0040023260.023
negative regulation of rna biosynthetic processGO:19026792400.023
cellular amine metabolic processGO:0044106120.023
maintenance of protein locationGO:0045185280.023
establishment of protein localizationGO:00451841630.022
membrane organizationGO:00610241120.022
negative regulation of cytoskeleton organizationGO:0051494300.022
ras protein signal transductionGO:0007265880.022
apoptotic processGO:00069151590.022
negative regulation of transcription dna templatedGO:00458922370.022
cellular catabolic processGO:00442483720.021
regulation of phosphate metabolic processGO:00192202100.021
regulation of organelle organizationGO:00330431960.021
establishment of cell polarityGO:0030010400.021
regulation of programmed cell deathGO:00430671520.021
regulation of anatomical structure morphogenesisGO:00226032420.020
spindle stabilizationGO:0043146140.020
nucleobase containing small molecule metabolic processGO:00550861740.020
male pronucleus assemblyGO:003503960.020
asymmetric stem cell divisionGO:0098722490.020
rna processingGO:00063961470.020
positive regulation of cell cycleGO:0045787430.019
regulation of response to stressGO:00801342000.019
purine nucleoside metabolic processGO:00422781270.019
positive regulation of cellular component organizationGO:00511301560.019
negative regulation of cellular biosynthetic processGO:00313272770.019
nucleus localizationGO:0051647340.019
stem cell proliferationGO:0072089880.019
regulation of neurogenesisGO:00507671580.019
protein dna complex subunit organizationGO:0071824860.019
regulation of protein modification processGO:00313991120.019
resolution of meiotic recombination intermediatesGO:000071260.018
regulation of localizationGO:00328792750.018
positive regulation of cellular biosynthetic processGO:00313283160.018
positive regulation of nitrogen compound metabolic processGO:00511733540.018
cystoblast divisionGO:0007282100.018
nucleoside triphosphate catabolic processGO:00091431080.018
negative regulation of signal transduction by p53 class mediatorGO:190179710.017
rho protein signal transductionGO:0007266140.017
ribonucleoprotein complex disassemblyGO:003298810.017
regulation of cellular catabolic processGO:00313291570.017
cellular protein modification processGO:00064644380.017
response to other organismGO:00517072930.017
regulation of apoptotic cell clearanceGO:200042520.017
positive regulation of cellular catabolic processGO:0031331950.017
pole cell formationGO:0007279190.017
regulation of microtubule based processGO:0032886490.016
carbohydrate derivative metabolic processGO:19011352170.016
sister chromatid segregationGO:0000819920.016
regulation of cellular component biogenesisGO:00440872010.016
regulation of cell deathGO:00109411730.016
proteolysisGO:00065081920.016
protein transportGO:00150311550.016
regulation of g1 s transition of mitotic cell cycleGO:2000045230.016
actomyosin contractile ring contractionGO:0000916120.016
macromolecular complex disassemblyGO:0032984370.015
microtubule polymerization or depolymerizationGO:0031109390.015
snrna metabolic processGO:0016073140.015
developmental maturationGO:00217001720.015
mitotic nuclear divisionGO:00070672130.015
intracellular protein transportGO:00068861040.015
protein phosphorylationGO:00064681690.015
positive regulation of catalytic activityGO:00430851180.015
protein importGO:0017038550.015
female meiotic divisionGO:0007143700.015
developmental growthGO:00485892800.015
regulation of mitotic spindle elongationGO:003288810.015
intrinsic apoptotic signaling pathwayGO:0097193160.015
mrna metabolic processGO:00160711240.015
oocyte maturationGO:000155630.015
positive regulation of biosynthetic processGO:00098913160.015
negative regulation of gtpase activityGO:003426010.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
endocytosisGO:00068973100.014
peptidyl amino acid modificationGO:00181931050.014
carbohydrate derivative catabolic processGO:19011361180.014
negative regulation of protein complex disassemblyGO:0043242230.014
positive regulation of protein modification processGO:0031401580.014
segmentationGO:00352822070.014
single organism membrane organizationGO:0044802930.014
regulation of transportGO:00510491810.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
chitin based larval cuticle pattern formationGO:0035293110.013
phosphorylationGO:00163102940.013
negative regulation of signal transductionGO:00099682060.013
nucleotide metabolic processGO:00091171610.013
negative regulation of cell communicationGO:00106482230.013
immune responseGO:00069552460.013
regulation of protein localizationGO:0032880760.013
nucleoside phosphate metabolic processGO:00067531620.013
oocyte dorsal ventral axis specificationGO:0007310340.013
positive regulation of molecular functionGO:00440931360.013
regulation of multi organism processGO:00439001310.013
regulation of hemocyte proliferationGO:0035206370.012
regulation of cell cycle processGO:00105641810.012
glycosyl compound metabolic processGO:19016571270.012
regulation of dna metabolic processGO:0051052340.012
spermatid differentiationGO:00485151140.012
regulation of neuron differentiationGO:00456641030.012
nucleobase containing compound catabolic processGO:00346551650.012
actin filament organizationGO:00070151260.012
regulation of cellular response to stressGO:0080135890.012
negative regulation of gtp catabolic processGO:003312510.012
pole cell developmentGO:0007277260.012
response to biotic stimulusGO:00096072940.012
regulation of catabolic processGO:00098941700.012
regulation of ras protein signal transductionGO:0046578930.012
regulation of apoptotic processGO:00429811300.012
camera type eye morphogenesisGO:004859320.011
snrna processingGO:0016180140.011
synapse assemblyGO:00074161430.011
syncytial blastoderm mitotic cell cycleGO:0035186210.011
oocyte axis specificationGO:00073091080.011
regulation of cellular ketone metabolic processGO:001056530.011
negative regulation of gene expression epigeneticGO:0045814770.011
ribose phosphate metabolic processGO:00196931450.011
cellular response to dna damage stimulusGO:00069742230.011
ubiquitin dependent protein catabolic processGO:0006511780.011
response to organic substanceGO:00100332840.011
mitotic sister chromatid segregationGO:0000070870.011
organophosphate catabolic processGO:00464341120.011
cell projection assemblyGO:0030031940.011
cytokinetic cell separationGO:000092010.010
cellular macromolecule catabolic processGO:00442651360.010
regulation of intracellular transportGO:0032386640.010
mitotic cell cycle checkpointGO:0007093880.010
negative regulation of developmental processGO:00510932010.010
agingGO:00075681430.010
regulation of transcription from rna polymerase ii promoterGO:00063573780.010

spd-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012