Drosophila melanogaster

133 known processes

l(3)mbt (Dmel_CG5954)

lethal (3) malignant brain tumor

(Aliases: MBT,Dmel\CG5954,l(3)malignant braintumor,dl(3)MBT,mbt,L(3)mbt,L(3)MBT/LIN-61,L(3)MBT,CG5954,L3mbt)

l(3)mbt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycle processGO:00105641810.406
Human
blastoderm segmentationGO:00073501590.383
chromosome organizationGO:00512763600.296
Human
peptidyl lysine modificationGO:0018205570.270
developmental growthGO:00485892800.270
Fly
negative regulation of gene expressionGO:00106293870.257
internal peptidyl lysine acetylationGO:0018393380.253
chromatin modificationGO:00165681470.228
Human
covalent chromatin modificationGO:00165691060.217
regulation of transcription from rna polymerase ii promoterGO:00063573780.212
stem cell proliferationGO:0072089880.203
internal protein amino acid acetylationGO:0006475380.190
positive regulation of molecular functionGO:00440931360.182
transcription from rna polymerase ii promoterGO:00063663680.180
tube morphogenesisGO:00352391910.178
organelle fissionGO:00482853400.175
Human
dna metabolic processGO:00062592270.163
chromosome segregationGO:00070591570.160
regulation of cellular amino acid metabolic processGO:000652100.160
histone acetylationGO:0016573380.156
protein modification processGO:00362114380.155
embryo development ending in birth or egg hatchingGO:00097921520.151
neurological system processGO:00508773580.145
chromatin organizationGO:00063252070.140
Human
histone modificationGO:00165701060.134
negative regulation of rna metabolic processGO:00512532510.132
dna conformation changeGO:00711031050.123
peptidyl amino acid modificationGO:00181931050.102
embryonic development via the syncytial blastodermGO:00017001480.097
protein acylationGO:0043543420.096
protein acetylationGO:0006473390.090
negative regulation of rna biosynthetic processGO:19026792400.088
regulation of cellular amine metabolic processGO:003323830.085
dendrite morphogenesisGO:00488131990.085
negative regulation of cellular biosynthetic processGO:00313272770.079
cell divisionGO:00513012480.078
Human
endocytosisGO:00068973100.078
cellular ketone metabolic processGO:0042180240.078
stem cell differentiationGO:00488631170.077
anterior posterior pattern specificationGO:00099521360.070
response to abiotic stimulusGO:00096283410.070
response to radiationGO:00093141550.069
negative regulation of cellular metabolic processGO:00313243820.069
immune system developmentGO:0002520570.068
Human Mouse
protein modification by small protein conjugation or removalGO:00706471060.068
peptidyl lysine acetylationGO:0018394390.065
cell proliferationGO:00082832990.061
negative regulation of gene expression epigeneticGO:0045814770.061
Fly
regulation of organelle organizationGO:00330431960.059
Human
positive regulation of catalytic activityGO:00430851180.059
cellular response to dna damage stimulusGO:00069742230.059
negative regulation of macromolecule biosynthetic processGO:00105582700.059
mitotic sister chromatid segregationGO:0000070870.056
positive regulation of biosynthetic processGO:00098913160.056
regulation of developmental pigmentationGO:0048070240.056
response to sterolGO:0036314340.055
determination of adult lifespanGO:00083401370.054
protein ubiquitinationGO:0016567700.053
regulation of gene expression epigeneticGO:00400291280.052
Fly
cellular response to abiotic stimulusGO:0071214580.052
central nervous system developmentGO:00074172010.051
small molecule metabolic processGO:00442813050.051
nuclear dna replicationGO:003326010.049
long term memoryGO:0007616620.049
imaginal disc derived appendage developmentGO:00487373990.049
anterior posterior axis specificationGO:00099481090.047
ventral furrow formationGO:0007370170.046
phagocytosisGO:00069092150.046
negative regulation of nucleobase containing compound metabolic processGO:00459342610.046
carboxylic acid metabolic processGO:0019752920.046
single organism catabolic processGO:00447122280.045
neural precursor cell proliferationGO:0061351750.045
positive regulation of macromolecule metabolic processGO:00106044050.045
appendage morphogenesisGO:00351073970.045
mrna splicing via spliceosomeGO:0000398730.044
regulation of cell cycleGO:00517262910.043
regulation of protein metabolic processGO:00512462560.041
immune system processGO:00023763470.040
Human Mouse
regulation of cellular ketone metabolic processGO:001056530.040
protein modification by small protein conjugationGO:0032446790.040
negative regulation of biosynthetic processGO:00098902770.040
tripartite regional subdivisionGO:00073511030.040
negative regulation of nitrogen compound metabolic processGO:00511722650.039
regionalizationGO:00030024160.037
cellular protein modification processGO:00064644380.037
appendage developmentGO:00487364010.037
positive regulation of macromolecule biosynthetic processGO:00105572830.037
digestive tract developmentGO:00485651490.037
positive regulation of cellular biosynthetic processGO:00313283160.037
gene silencingGO:00164581380.036
Fly
regulation of protein modification processGO:00313991120.035
regulation of catalytic activityGO:00507901850.035
negative regulation of nucleic acid templated transcriptionGO:19035072400.035
mitotic cell cycle phase transitionGO:00447721380.035
heart developmentGO:0007507820.034
imaginal disc derived appendage morphogenesisGO:00351143950.034
regulation of notch signaling pathwayGO:00085931000.034
regulation of molecular functionGO:00650092170.034
protein catabolic processGO:00301631010.033
histone h4 acetylationGO:0043967130.033
response to organic substanceGO:00100332840.033
positive regulation of cellular amino acid metabolic processGO:004576400.033
mesenchymal cell developmentGO:001403110.033
dna replicationGO:0006260480.032
intracellular signal transductionGO:00355563000.031
cellular catabolic processGO:00442483720.031
stem cell developmentGO:0048864790.031
proteolysisGO:00065081920.030
post embryonic appendage morphogenesisGO:00351203850.030
cell cycle phase transitionGO:00447701400.029
eye photoreceptor cell differentiationGO:00017541450.029
organic acid metabolic processGO:00060821030.029
single organism behaviorGO:00447083910.028
female meiosis chromosome segregationGO:0016321330.028
programmed cell deathGO:00125012570.028
positive regulation of catabolic processGO:00098961050.027
kidney morphogenesisGO:006099330.027
chromatin remodelingGO:0006338720.027
hematopoietic or lymphoid organ developmentGO:0048534570.027
Human Mouse
camera type eye developmentGO:004301040.026
organ growthGO:0035265560.026
Fly
mitotic nuclear divisionGO:00070672130.026
Human
regulation of multicellular organismal developmentGO:20000264140.026
axis specificationGO:00097981670.025
regulation of intracellular signal transductionGO:19025312360.025
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
vesicle mediated transportGO:00161923810.025
chromatin silencingGO:0006342760.025
Fly
response to biotic stimulusGO:00096072940.025
regulation of nuclear divisionGO:0051783580.024
Human
regulation of small gtpase mediated signal transductionGO:0051056930.024
multi organism behaviorGO:00517051750.024
head developmentGO:00603221350.023
positive regulation of cellular protein metabolic processGO:00322701180.023
rna interferenceGO:0016246270.023
developmental maturationGO:00217001720.023
Mouse
nucleoside triphosphate catabolic processGO:00091431080.023
negative regulation of cellular protein metabolic processGO:0032269850.023
mitotic cell cycle embryonicGO:0045448380.023
taxisGO:00423303040.022
lymph gland developmentGO:0048542280.022
response to light stimulusGO:00094161240.022
organonitrogen compound metabolic processGO:19015643180.022
muscle cell differentiationGO:00426921030.022
tube developmentGO:00352952440.022
embryonic axis specificationGO:00005781070.021
regulation of g2 m transition of mitotic cell cycleGO:0010389150.021
gland developmentGO:00487321910.021
renal tubule developmentGO:0061326640.020
respiratory system developmentGO:00605412130.020
neuronal stem cell maintenanceGO:009715040.020
columnar cuboidal epithelial cell differentiationGO:00020652560.020
cellular response to organic substanceGO:00713101320.020
macromolecular complex assemblyGO:00650032560.020
cell fate specificationGO:0001708710.020
regulation of neural precursor cell proliferationGO:2000177350.020
single organism biosynthetic processGO:00447112060.020
morphogenesis of an epitheliumGO:00020092760.020
regulation of cell divisionGO:0051302720.019
Human
dna packagingGO:0006323910.019
protein phosphorylationGO:00064681690.019
wing disc morphogenesisGO:00074723440.019
segmentationGO:00352822070.019
regulation of circadian rhythmGO:0042752490.019
actomyosin structure organizationGO:0031032560.019
positive regulation of rna biosynthetic processGO:19026802660.019
regulation of phosphorus metabolic processGO:00511742100.019
eye developmentGO:00016543230.018
deathGO:00162652840.018
histone mrna metabolic processGO:000833480.018
chromatin assembly or disassemblyGO:0006333520.018
purine ribonucleotide catabolic processGO:00091541090.018
regulation of cellular protein metabolic processGO:00322682430.018
positive regulation of protein metabolic processGO:00512471280.018
cuticle developmentGO:0042335860.017
response to external biotic stimulusGO:00432072930.017
negative regulation of signal transductionGO:00099682060.017
organelle assemblyGO:00709251980.017
negative regulation of g2 m transition of mitotic cell cycleGO:001097280.017
regulation of i kappab kinase nf kappab signalingGO:004312220.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.017
smoothened signaling pathwayGO:0007224490.017
cell fate determinationGO:0001709910.016
mrna processingGO:00063971040.016
multi organism reproductive behaviorGO:00447051210.016
regulation of histone modificationGO:0031056200.016
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.016
cellular protein catabolic processGO:0044257830.016
cellular response to external stimulusGO:0071496660.016
multicellular organismal agingGO:00102591400.016
outflow tract morphogenesisGO:000315140.016
proteolysis involved in cellular protein catabolic processGO:0051603830.016
macromolecule methylationGO:0043414450.016
ribonucleoprotein complex assemblyGO:0022618230.016
dna damage checkpointGO:0000077780.016
ribonucleoside triphosphate metabolic processGO:00091991190.016
rna splicingGO:0008380830.016
regulation of cell differentiationGO:00455953020.016
Human
spindle organizationGO:00070512530.016
purine containing compound catabolic processGO:00725231120.015
urogenital system developmentGO:0001655720.015
dendrite developmentGO:00163582040.015
imaginal disc growthGO:0007446370.015
Fly
regulation of embryonic developmentGO:0045995680.015
learning or memoryGO:00076111410.015
nucleoside phosphate catabolic processGO:19012921100.015
imaginal disc derived wing morphogenesisGO:00074763370.015
purine ribonucleoside triphosphate catabolic processGO:00092071080.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
malpighian tubule developmentGO:0072002640.015
embryonic pattern specificationGO:00098801740.015
catabolic processGO:00090564090.015
chromosome condensationGO:0030261410.015
negative regulation of protein metabolic processGO:0051248850.014
cellular response to nutrient levelsGO:0031669620.014
negative regulation of programmed cell deathGO:0043069720.014
purine nucleotide metabolic processGO:00061631460.014
positive regulation of response to stimulusGO:00485843230.014
regulation of mitotic cell cycleGO:00073461900.014
mushroom body developmentGO:0016319700.014
positive regulation of multicellular organismal processGO:00512401430.014
notch signaling pathwayGO:00072191200.014
cellular macromolecular complex assemblyGO:00346221530.014
dna repairGO:0006281540.014
renal tubule morphogenesisGO:0061333440.014
ubiquitin dependent protein catabolic processGO:0006511780.014
tissue morphogenesisGO:00487292970.014
compound eye developmentGO:00487493070.014
regulation of programmed cell deathGO:00430671520.014
positive regulation of cellular amine metabolic processGO:003324000.013
growthGO:00400073590.013
Fly
digestive tract morphogenesisGO:00485461270.013
negative regulation of multicellular organismal processGO:00512411420.013
Worm
cellular response to extracellular stimulusGO:0031668640.013
forebrain developmentGO:003090020.013
regulation of cellular response to stressGO:0080135890.013
organic substance catabolic processGO:19015753080.013
cellular response to chemical stimulusGO:00708871990.013
regulation of nervous system developmentGO:00519602480.013
actin cytoskeleton organizationGO:00300362060.013
regulation of reproductive processGO:2000241540.013
positive regulation of transcription dna templatedGO:00458932660.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
regulation of gtpase activityGO:0043087440.013
imaginal disc derived leg morphogenesisGO:0007480800.013
spinal cord developmentGO:002151010.013
mrna metabolic processGO:00160711240.012
chemotaxisGO:00069352490.012
regulation of cell cycle phase transitionGO:19019871300.012
nucleosome assemblyGO:0006334350.012
regulation of stem cell proliferationGO:0072091400.012
innate immune responseGO:00450871440.012
response to nutrient levelsGO:00316671140.012
oxoacid metabolic processGO:00434361030.012
male courtship behavior veined wing generated song productionGO:0045433200.012
purine ribonucleotide metabolic processGO:00091501450.012
regulation of gtp catabolic processGO:0033124440.012
nucleoside triphosphate metabolic processGO:00091411200.012
homeostatic processGO:00425921990.012
Mouse
regulation of catabolic processGO:00098941700.012
rna splicing via transesterification reactionsGO:0000375730.012
negative regulation of cell deathGO:0060548810.012
cellular response to ketoneGO:1901655170.012
cytoplasm organizationGO:0007028640.012
negative regulation of developmental processGO:00510932010.012
Worm
cell motilityGO:00488702510.012
response to starvationGO:0042594970.012
positive regulation of nitrogen compound metabolic processGO:00511733540.012
cellular component assembly involved in morphogenesisGO:00109271510.012
modification dependent macromolecule catabolic processGO:0043632790.012
response to other organismGO:00517072930.012
negative regulation of cell cycleGO:00457861160.012
organophosphate catabolic processGO:00464341120.012
positive regulation of mitotic cell cycleGO:0045931340.011
regulation of chromosome segregationGO:0051983320.011
epithelial cell developmentGO:00020642740.011
karyosome formationGO:0030717220.011
posttranscriptional gene silencingGO:0016441460.011
small gtpase mediated signal transductionGO:0007264880.011
response to oxygen containing compoundGO:19017002000.011
macromolecule catabolic processGO:00090571610.011
crystal cell differentiationGO:004268870.011
brain developmentGO:00074201200.011
larval locomotory behaviorGO:0008345270.011
molting cycle chitin based cuticleGO:0007591560.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
negative regulation of cell differentiationGO:00455961430.011
positive regulation of gene expressionGO:00106282900.010
regulation of nucleoside metabolic processGO:0009118500.010
regulation of oocyte developmentGO:0060281270.010
regulation of multi organism processGO:00439001310.010
regulation of mitotic cell cycle phase transitionGO:19019901300.010
pole plasm protein localizationGO:0007318100.010
purine containing compound metabolic processGO:00725211550.010
response to ketoneGO:1901654340.010
larval developmentGO:00021641040.010
Worm
nucleotide metabolic processGO:00091171610.010
neuron fate commitmentGO:0048663500.010
cell deathGO:00082192790.010
regulation of phosphate metabolic processGO:00192202100.010
purine nucleoside triphosphate metabolic processGO:00091441190.010
regulation of sister chromatid segregationGO:0033045280.010
negative regulation of apoptotic processGO:0043066630.010
regulation of purine nucleotide catabolic processGO:0033121480.010
neuroblast differentiationGO:0014016290.010
retina development in camera type eyeGO:006004140.010
spliceosomal snrnp assemblyGO:000038720.010

l(3)mbt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015