Drosophila melanogaster

10 known processes

rux (Dmel_CG4336)

roughex

(Aliases: CG4336,Rux,Dmel\CG4336)

rux biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycle phase transitionGO:19019871300.819
meiosis iGO:0007127590.766
regulation of cell cycle processGO:00105641810.765
regionalizationGO:00030024160.746
regulation of cell cycleGO:00517262910.724
negative regulation of mitotic cell cycle phase transitionGO:19019911030.582
negative regulation of cell cycle phase transitionGO:19019881030.564
meiotic nuclear divisionGO:00071261510.554
nuclear divisionGO:00002803320.528
organelle fissionGO:00482853400.478
mitotic cell cycle phase transitionGO:00447721380.467
negative regulation of mitotic cell cycleGO:00459301090.438
regulation of mitotic cell cycleGO:00073461900.423
cell divisionGO:00513012480.416
cell cycle phase transitionGO:00447701400.401
dna metabolic processGO:00062592270.334
meiotic cell cycle processGO:19030461320.261
mitotic nuclear divisionGO:00070672130.256
regulation of mitotic cell cycle phase transitionGO:19019901300.249
protein complex assemblyGO:00064612000.243
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.233
negative regulation of cell cycleGO:00457861160.208
regulation of synapse organizationGO:00508071100.194
regulation of cell divisionGO:0051302720.185
protein complex biogenesisGO:00702712010.178
synaptic growth at neuromuscular junctionGO:00511241190.166
regulation of nuclear divisionGO:0051783580.160
regulation of microtubule cytoskeleton organizationGO:0070507410.146
regulation of organelle organizationGO:00330431960.139
cystoblast divisionGO:0007282100.137
imaginal disc derived appendage developmentGO:00487373990.135
synapse assemblyGO:00074161430.135
developmental maturationGO:00217001720.133
cell projection assemblyGO:0030031940.132
regulation of synapse structure and activityGO:00508031280.131
negative regulation of cellular component organizationGO:00511291080.128
negative regulation of chromosome segregationGO:0051985140.127
regulation of chromosome segregationGO:0051983320.119
post embryonic appendage morphogenesisGO:00351203850.118
vesicle mediated transportGO:00161923810.116
regulation of nervous system developmentGO:00519602480.106
regulation of synaptic growth at neuromuscular junctionGO:0008582890.101
regulation of synapse assemblyGO:0051963940.099
regulation of multicellular organismal developmentGO:20000264140.099
meiotic sister chromatid segregationGO:004514460.099
ubiquitin dependent protein catabolic processGO:0006511780.097
male gamete generationGO:00482322010.097
negative regulation of cell cycle processGO:00109481090.092
oocyte maturationGO:000155630.089
embryo development ending in birth or egg hatchingGO:00097921520.088
endocytosisGO:00068973100.085
morphogenesis of an epitheliumGO:00020092760.085
negative regulation of reactive oxygen species metabolic processGO:200037810.085
anterior posterior pattern specificationGO:00099521360.084
negative regulation of synapse assemblyGO:0051964390.083
meiotic cell cycleGO:00513211710.082
oocyte developmentGO:00485991240.079
regulation of mitosisGO:0007088560.078
negative regulation of nervous system developmentGO:0051961920.078
cytokinesisGO:0000910900.076
digestive tract developmentGO:00485651490.075
open tracheal system developmentGO:00074242040.073
macromolecular complex assemblyGO:00650032560.072
spermatid developmentGO:0007286980.072
positive regulation of biosynthetic processGO:00098913160.070
positive regulation of gene expressionGO:00106282900.070
cytoskeleton dependent cytokinesisGO:0061640810.069
negative regulation of cellular catabolic processGO:0031330340.069
developmental growthGO:00485892800.068
regulation of cellular component biogenesisGO:00440872010.067
mitotic cell cycle checkpointGO:0007093880.066
axis specificationGO:00097981670.066
cell maturationGO:00484691440.065
dendrite morphogenesisGO:00488131990.064
female meiotic divisionGO:0007143700.064
tube morphogenesisGO:00352391910.062
eye developmentGO:00016543230.060
organelle assemblyGO:00709251980.059
spermatogenesisGO:00072832000.057
wing disc morphogenesisGO:00074723440.054
mitotic cell cycle embryonicGO:0045448380.054
segmentationGO:00352822070.053
dendrite developmentGO:00163582040.052
embryonic pattern specificationGO:00098801740.051
regulation of cytoskeleton organizationGO:0051493890.051
apoptotic processGO:00069151590.051
cell cycle dna replicationGO:0044786230.050
phagocytosisGO:00069092150.050
chromosome separationGO:0051304420.049
positive regulation of nucleic acid templated transcriptionGO:19035082660.049
mitotic spindle checkpointGO:0071174110.048
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.047
embryonic axis specificationGO:00005781070.047
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.046
negative regulation of mitotic sister chromatid separationGO:2000816130.046
regulation of growthGO:00400082330.046
asymmetric neuroblast divisionGO:0055059330.045
pronuclear migrationGO:003504640.045
negative regulation of sister chromatid segregationGO:0033046130.045
g2 m transition of mitotic cell cycleGO:0000086190.045
positive regulation of macromolecule metabolic processGO:00106044050.044
mitotic sister chromatid separationGO:0051306300.044
positive regulation of signal transductionGO:00099672230.044
rna localizationGO:00064031150.044
synapse organizationGO:00508081960.043
protein catabolic processGO:00301631010.043
regulation of tube architecture open tracheal systemGO:0035152680.042
transcription from rna polymerase ii promoterGO:00063663680.042
sensory organ morphogenesisGO:00905962600.042
regulation of cell proliferationGO:00421271630.041
regulation of mitotic metaphase anaphase transitionGO:0030071260.040
negative regulation of developmental processGO:00510932010.040
response to light stimulusGO:00094161240.039
negative regulation of proteasomal protein catabolic processGO:1901799160.039
regulation of microtubule based processGO:0032886490.039
regulation of dna replicationGO:0006275130.039
neuromuscular junction developmentGO:00075281490.038
positive regulation of signalingGO:00230562430.038
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.037
positive regulation of cellular component organizationGO:00511301560.037
cilium morphogenesisGO:0060271390.037
regulation of mitotic sister chromatid separationGO:0010965280.037
epidermal growth factor receptor signaling pathwayGO:0007173580.037
regulation of intracellular signal transductionGO:19025312360.037
mitotic sister chromatid segregationGO:0000070870.037
negative regulation of organelle organizationGO:0010639560.037
respiratory system developmentGO:00605412130.036
cilium assemblyGO:0042384380.036
positive regulation of macromolecule biosynthetic processGO:00105572830.035
regulation of cellular catabolic processGO:00313291570.035
anterior posterior axis specificationGO:00099481090.035
negative regulation of mitotic sister chromatid segregationGO:0033048130.035
nucleus organizationGO:0006997450.034
appendage developmentGO:00487364010.034
meiotic spindle organizationGO:0000212360.034
blastoderm segmentationGO:00073501590.034
determination of adult lifespanGO:00083401370.032
stem cell divisionGO:0017145690.032
sister chromatid segregationGO:0000819920.032
rhythmic processGO:00485111060.032
anatomical structure homeostasisGO:0060249970.031
cellular nitrogen compound catabolic processGO:00442701650.030
organelle localizationGO:00516401480.030
positive regulation of cellular biosynthetic processGO:00313283160.030
tube developmentGO:00352952440.030
chromosome segregationGO:00070591570.030
appendage morphogenesisGO:00351073970.029
locomotory behaviorGO:00076261760.029
negative regulation of growthGO:0045926840.029
imaginal disc derived wing morphogenesisGO:00074763370.029
proteolysis involved in cellular protein catabolic processGO:0051603830.028
cilium organizationGO:0044782410.028
embryonic morphogenesisGO:00485982060.028
spindle checkpointGO:0031577110.027
mitotic cytokinesisGO:0000281500.027
regulation of apoptotic processGO:00429811300.027
regulation of cell developmentGO:00602842150.027
tripartite regional subdivisionGO:00073511030.027
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.027
response to endogenous stimulusGO:00097191190.027
macromolecule catabolic processGO:00090571610.027
regulation of mitotic sister chromatid segregationGO:0033047280.027
male meiosisGO:0007140520.026
negative regulation of cell divisionGO:0051782170.026
neuroblast proliferationGO:0007405740.026
chromosome organizationGO:00512763600.026
programmed cell deathGO:00125012570.026
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.026
nitrogen compound transportGO:0071705850.026
single organism biosynthetic processGO:00447112060.025
digestive tract morphogenesisGO:00485461270.025
imaginal disc derived appendage morphogenesisGO:00351143950.025
microtubule based movementGO:0007018510.025
germ line cyst formationGO:0048134440.025
body morphogenesisGO:001017120.025
peptidyl threonine phosphorylationGO:001810720.025
cellular protein modification processGO:00064644380.025
metaphase anaphase transition of cell cycleGO:0044784280.025
protein complex disassemblyGO:0043241360.025
regulation of meiosisGO:004002030.024
modification dependent protein catabolic processGO:0019941780.024
posttranscriptional regulation of gene expressionGO:00106081450.024
tissue morphogenesisGO:00487292970.024
regulation of neuron projection developmentGO:0010975690.024
endomembrane system organizationGO:00102561190.024
oocyte differentiationGO:00099941450.024
positive regulation of nitrogen compound metabolic processGO:00511733540.023
regulation of sister chromatid segregationGO:0033045280.023
digestive system developmentGO:00551231490.023
negative regulation of multicellular organismal processGO:00512411420.023
response to organic substanceGO:00100332840.023
response to abiotic stimulusGO:00096283410.023
negative regulation of catabolic processGO:0009895360.022
cellular protein catabolic processGO:0044257830.022
meiotic cell cycle phase transitionGO:004477140.022
regulation of translationGO:0006417560.022
meiosis iiGO:0007135230.022
negative regulation of cell developmentGO:0010721620.022
intracellular signal transductionGO:00355563000.022
regulation of epithelial cell proliferationGO:005067840.022
protein ubiquitinationGO:0016567700.022
mitochondrial fusionGO:000805370.022
organic cyclic compound catabolic processGO:19013611680.022
establishment or maintenance of bipolar cell polarityGO:0061245340.021
protein k48 linked ubiquitinationGO:007093630.021
metaphase anaphase transition of mitotic cell cycleGO:0007091280.021
positive regulation of response to stimulusGO:00485843230.021
gastrulation with mouth forming firstGO:0001703360.021
cellular amine metabolic processGO:0044106120.021
response to radiationGO:00093141550.021
axon guidanceGO:00074112330.021
negative regulation of mitotic metaphase anaphase transitionGO:0045841130.020
regulation of membrane potentialGO:0042391350.020
establishment of localization in cellGO:00516494020.020
regulation of spindle organizationGO:0090224170.020
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.020
positive regulation of nurse cell apoptotic processGO:004585050.020
peptidyl tyrosine phosphorylationGO:0018108240.020
positive regulation of cell communicationGO:00106472500.020
regulation of chromosome organizationGO:0033044640.020
dna replicationGO:0006260480.020
positive regulation of protein metabolic processGO:00512471280.020
regulation of dendrite developmentGO:0050773370.019
negative regulation of metaphase anaphase transition of cell cycleGO:1902100130.019
germarium derived female germ line cyst formationGO:0030727420.019
meiotic cytokinesisGO:0033206330.019
peripheral nervous system developmentGO:0007422520.019
synaptic transmission dopaminergicGO:000196320.019
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.019
compound eye developmentGO:00487493070.019
negative regulation of epithelial cell proliferationGO:005068040.019
syncytial blastoderm mitotic cell cycleGO:0035186210.019
female germ line cyst formationGO:0048135420.019
camera type eye morphogenesisGO:004859320.018
cell cycle g2 m phase transitionGO:0044839220.018
regulation of microtubule depolymerizationGO:0031114240.018
centrosome organizationGO:00512971630.018
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.018
axonogenesisGO:00074092900.018
response to endoplasmic reticulum stressGO:0034976280.018
positive regulation of developmental processGO:00510941430.018
protein processingGO:0016485680.018
regulation of cell deathGO:00109411730.018
positive regulation of cellular protein catabolic processGO:1903364240.018
chromosome organization involved in meiosisGO:0070192100.018
cell cycle g1 s phase transitionGO:0044843310.017
response to copper ionGO:004668840.017
positive regulation of phosphorus metabolic processGO:00105621390.017
sperm individualizationGO:0007291480.017
cell cycle checkpointGO:0000075950.017
negative regulation of mitosisGO:0045839160.017
dorsal ventral axis specificationGO:0009950660.016
protein maturationGO:0051604710.016
asymmetric cell divisionGO:0008356370.016
negative regulation of protein catabolic processGO:0042177170.016
mitotic spindle assembly checkpointGO:0007094110.016
regulation of dna metabolic processGO:0051052340.016
neuroblast divisionGO:0055057350.016
social behaviorGO:003517640.016
positive regulation of transcription dna templatedGO:00458932660.016
multicellular organismal agingGO:00102591400.016
sex differentiationGO:0007548810.015
regulation of developmental growthGO:00486381740.015
camera type eye developmentGO:004301040.015
negative regulation of neurogenesisGO:0050768530.015
regulation of oocyte developmentGO:0060281270.015
negative regulation of chromosome organizationGO:2001251190.015
cellular macromolecule catabolic processGO:00442651360.015
anterograde axon cargo transportGO:000808960.015
phosphorylationGO:00163102940.015
gliogenesisGO:0042063800.015
cellular response to organic substanceGO:00713101320.015
cellular catabolic processGO:00442483720.015
agingGO:00075681430.015
positive regulation of organelle organizationGO:0010638650.015
oxoacid metabolic processGO:00434361030.014
cation transportGO:00068121100.014
establishment of organelle localizationGO:00516561220.014
organic substance catabolic processGO:19015753080.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
negative regulation of programmed cell deathGO:0043069720.014
proteasomal protein catabolic processGO:0010498590.014
cell proliferationGO:00082832990.014
intracellular transportGO:00469072280.014
synaptic transmissionGO:00072682880.014
cell agingGO:000756920.014
spindle assemblyGO:0051225800.014
retina development in camera type eyeGO:006004140.014
actin cytoskeleton organizationGO:00300362060.014
epithelial structure maintenanceGO:0010669170.014
neuron projection guidanceGO:00974852410.014
positive regulation of lipid catabolic processGO:005099610.014
lateral inhibitionGO:00463312060.014
positive regulation of proteasomal protein catabolic processGO:1901800200.014
cell deathGO:00082192790.013
g1 s transition of mitotic cell cycleGO:0000082310.013
cellular protein complex assemblyGO:0043623710.013
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.013
mrna metabolic processGO:00160711240.013
forebrain developmentGO:003090020.013
negative regulation of protein metabolic processGO:0051248850.013
intracellular protein transportGO:00068861040.013
regulation of neurogenesisGO:00507671580.013
carboxylic acid metabolic processGO:0019752920.013
dna double strand break processingGO:000072930.013
response to other organismGO:00517072930.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.012
nucleobase containing compound transportGO:0015931560.012
response to oxygen containing compoundGO:19017002000.012
eye morphogenesisGO:00485922600.012
nucleobase containing compound catabolic processGO:00346551650.012
covalent chromatin modificationGO:00165691060.012
cell cycle comprising mitosis without cytokinesisGO:0033301250.012
regulation of response to stressGO:00801342000.012
positive regulation of rna metabolic processGO:00512542710.012
single organism cellular localizationGO:19025801800.012
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.012
chemotaxisGO:00069352490.012
regulation of protein depolymerizationGO:1901879270.012
growthGO:00400073590.012
endomitotic cell cycleGO:000711370.012
telomere organizationGO:0032200210.012
stem cell differentiationGO:00488631170.012
regulation of proteasomal protein catabolic processGO:0061136390.012
germarium derived egg chamber formationGO:00072931010.011
centrosome separationGO:0051299200.011
ribose phosphate metabolic processGO:00196931450.011
glial cell differentiationGO:0010001350.011
negative regulation of cytoskeleton organizationGO:0051494300.011
regulation of metaphase anaphase transition of cell cycleGO:1902099260.011
organic acid metabolic processGO:00060821030.011
regulation of neuron differentiationGO:00456641030.011
cytokinetic processGO:0032506270.011
dna endoreduplicationGO:0042023220.011
biological adhesionGO:00226101380.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of protein complex assemblyGO:0043254420.011
regulation of erbb signaling pathwayGO:1901184420.011
deathGO:00162652840.011
jak stat cascadeGO:0007259490.011
secretion by cellGO:00329401010.011
reproductive system developmentGO:0061458740.011
cellular response to chemical stimulusGO:00708871990.011
regulation of phosphate metabolic processGO:00192202100.011
catabolic processGO:00090564090.010
negative regulation of gene expressionGO:00106293870.010
regulation of protein dephosphorylationGO:003530450.010
maintenance of locationGO:0051235730.010
gland morphogenesisGO:00226121450.010
positive regulation of multicellular organismal processGO:00512401430.010
translationGO:0006412690.010
development of primary sexual characteristicsGO:0045137500.010
regulation of catabolic processGO:00098941700.010
cell cycle arrestGO:000705040.010

rux disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
nervous system diseaseDOID:86300.020
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
organ system cancerDOID:005068600.019
central nervous system diseaseDOID:33100.015
neurodegenerative diseaseDOID:128900.015