IMP: Integrative Multi-species Prediction

Drosophila melanogaster

36 known processes

CG15173 (Dmel_CG15173)

CG15173 gene product from transcript CG15173-RA

(Aliases: Dmel\CG15173)

Entrez: 35172
FLYBASE: FBgn0032744
UniProtKB: Q8SYD0

Process Predictions
Disease Predictions

CG15173 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
response to abiotic stimulus	GO:0009628	341	0.146
single organism cellular localization	GO:1902580	180	0.097	Fly
establishment of planar polarity	GO:0001736	87	0.084
regulation of anatomical structure morphogenesis	GO:0022603	242	0.078
regulation of cell differentiation	GO:0045595	302	0.073
aging	GO:0007568	143	0.072
male gamete generation	GO:0048232	201	0.071
establishment of tissue polarity	GO:0007164	87	0.068
death	GO:0016265	284	0.067
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.067
purine nucleoside metabolic process	GO:0042278	127	0.065
negative regulation of cellular metabolic process	GO:0031324	382	0.063
regulation of localization	GO:0032879	275	0.062	Fly
spermatid development	GO:0007286	98	0.061
single organism intracellular transport	GO:1902582	207	0.061
cell death	GO:0008219	279	0.060
cellularization	GO:0007349	90	0.058
homeostatic process	GO:0042592	199	0.057
morphogenesis of an epithelium	GO:0002009	276	0.055
endomembrane system organization	GO:0010256	119	0.053
establishment of localization in cell	GO:0051649	402	0.052
regulation of multicellular organismal development	GO:2000026	414	0.051
cellular response to dna damage stimulus	GO:0006974	223	0.050
regulation of cell death	GO:0010941	173	0.050
tissue morphogenesis	GO:0048729	297	0.049
cell proliferation	GO:0008283	299	0.049
apoptotic signaling pathway	GO:0097190	27	0.048
morphogenesis of a polarized epithelium	GO:0001738	93	0.047
lateral inhibition	GO:0046331	206	0.047
spermatogenesis	GO:0007283	200	0.045
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.045
phosphorylation	GO:0016310	294	0.045
membrane organization	GO:0061024	112	0.043
organonitrogen compound metabolic process	GO:1901564	318	0.042
nucleoside metabolic process	GO:0009116	127	0.040
carbohydrate derivative metabolic process	GO:1901135	217	0.040
response to oxidative stress	GO:0006979	86	0.040
purine ribonucleoside metabolic process	GO:0046128	127	0.039
sensory perception	GO:0007600	196	0.039
organophosphate metabolic process	GO:0019637	195	0.039
multicellular organismal aging	GO:0010259	140	0.039
intracellular signal transduction	GO:0035556	300	0.038
single organism biosynthetic process	GO:0044711	206	0.038
atp metabolic process	GO:0046034	49	0.037
defense response	GO:0006952	300	0.037
protein localization	GO:0008104	284	0.037
protein complex assembly	GO:0006461	200	0.037
macromolecular complex assembly	GO:0065003	256	0.037
sperm individualization	GO:0007291	48	0.036
forebrain development	GO:0030900	2	0.036
cellular protein modification process	GO:0006464	438	0.035
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.035
positive regulation of macromolecule metabolic process	GO:0010604	405	0.034
protein modification process	GO:0036211	438	0.034
developmental programmed cell death	GO:0010623	138	0.034
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.033
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.033
nucleoside triphosphate metabolic process	GO:0009141	120	0.033
small molecule metabolic process	GO:0044281	305	0.033
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.032
single organism behavior	GO:0044708	391	0.031
locomotory behavior	GO:0007626	176	0.031
endoplasmic reticulum organization	GO:0007029	13	0.031
l glutamate import	GO:0051938	1	0.031
negative regulation of transcription dna templated	GO:0045892	237	0.031
transcription from rna polymerase ii promoter	GO:0006366	368	0.030
negative regulation of biosynthetic process	GO:0009890	277	0.030
positive regulation of developmental process	GO:0051094	143	0.030
central nervous system development	GO:0007417	201	0.030
mitochondrion organization	GO:0007005	65	0.029
purine ribonucleotide metabolic process	GO:0009150	145	0.029
positive regulation of response to stimulus	GO:0048584	323	0.029
intracellular protein transport	GO:0006886	104	0.029
nucleoside phosphate metabolic process	GO:0006753	162	0.029
establishment or maintenance of cell polarity	GO:0007163	167	0.028
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.028
detection of stimulus	GO:0051606	156	0.027
negative regulation of signal transduction	GO:0009968	206	0.027
programmed cell death	GO:0012501	257	0.026
ribose phosphate metabolic process	GO:0019693	145	0.026
negative regulation of cellular biosynthetic process	GO:0031327	277	0.026
positive regulation of biosynthetic process	GO:0009891	316	0.026
endocytosis	GO:0006897	310	0.026	Fly
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.026	Fly
positive regulation of signaling	GO:0023056	243	0.025
organic substance transport	GO:0071702	257	0.025
positive regulation of cellular biosynthetic process	GO:0031328	316	0.025
regulation of cell cycle	GO:0051726	291	0.025	Fly
adult behavior	GO:0030534	137	0.025
purine containing compound metabolic process	GO:0072521	155	0.025
synaptic growth at neuromuscular junction	GO:0051124	119	0.024
regulation of cellular protein metabolic process	GO:0032268	243	0.024
cell adhesion	GO:0007155	136	0.023
nucleobase containing compound catabolic process	GO:0034655	165	0.023
apoptotic process	GO:0006915	159	0.023
positive regulation of programmed cell death	GO:0043068	62	0.022
body morphogenesis	GO:0010171	2	0.022
positive regulation of signal transduction	GO:0009967	223	0.022
posttranscriptional regulation of gene expression	GO:0010608	145	0.022
regulation of developmental growth	GO:0048638	174	0.022
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.022
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.022
appendage morphogenesis	GO:0035107	397	0.022
negative regulation of gene expression	GO:0010629	387	0.022
epithelial cell differentiation	GO:0030855	322	0.021	Fly
neuromuscular junction development	GO:0007528	149	0.021
intracellular transport	GO:0046907	228	0.021
synaptic transmission	GO:0007268	288	0.021
protein complex biogenesis	GO:0070271	201	0.021
detection of visible light	GO:0009584	38	0.021
ribonucleotide metabolic process	GO:0009259	145	0.021
taxis	GO:0042330	304	0.021
positive regulation of transport	GO:0051050	92	0.021
lipid metabolic process	GO:0006629	121	0.021
nucleotide metabolic process	GO:0009117	161	0.020
determination of adult lifespan	GO:0008340	137	0.020
response to mechanical stimulus	GO:0009612	28	0.020
molting cycle	GO:0042303	56	0.020
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.020
glycosyl compound metabolic process	GO:1901657	127	0.020
nucleobase containing small molecule metabolic process	GO:0055086	174	0.020
negative regulation of cell communication	GO:0010648	223	0.020
regulation of organ morphogenesis	GO:2000027	78	0.019
response to radiation	GO:0009314	155	0.019
negative regulation of signaling	GO:0023057	219	0.019
nitrogen compound transport	GO:0071705	85	0.019
ribonucleoside metabolic process	GO:0009119	127	0.019
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.019
sensory organ morphogenesis	GO:0090596	260	0.019
regulation of transport	GO:0051049	181	0.019
columnar cuboidal epithelial cell development	GO:0002066	249	0.019	Fly
regulation of programmed cell death	GO:0043067	152	0.019
carboxylic acid metabolic process	GO:0019752	92	0.019
chromatin organization	GO:0006325	207	0.018
ion transport	GO:0006811	145	0.018
response to external biotic stimulus	GO:0043207	293	0.018
regulation of cell development	GO:0060284	215	0.018
detection of abiotic stimulus	GO:0009582	66	0.018
response to temperature stimulus	GO:0009266	106	0.018
organic hydroxy compound metabolic process	GO:1901615	83	0.018
negative regulation of response to stimulus	GO:0048585	258	0.018
retina development in camera type eye	GO:0060041	4	0.018
negative regulation of cellular protein metabolic process	GO:0032269	85	0.018
cellular nitrogen compound catabolic process	GO:0044270	165	0.018
negative regulation of programmed cell death	GO:0043069	72	0.018
cellular amino acid metabolic process	GO:0006520	61	0.018
purine nucleotide metabolic process	GO:0006163	146	0.018
positive regulation of transcription dna templated	GO:0045893	266	0.018
detection of light stimulus	GO:0009583	58	0.017
establishment of protein localization to membrane	GO:0090150	11	0.017
cation transmembrane transport	GO:0098655	88	0.017
regulation of membrane potential	GO:0042391	35	0.017
regulation of apoptotic process	GO:0042981	130	0.017
negative regulation of multicellular organismal process	GO:0051241	142	0.017
camera type eye development	GO:0043010	4	0.017
regulation of phosphorus metabolic process	GO:0051174	210	0.017
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.017
adult locomotory behavior	GO:0008344	76	0.017
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.017
heterocycle catabolic process	GO:0046700	166	0.016
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.016
positive regulation of cell communication	GO:0010647	250	0.016
intrinsic apoptotic signaling pathway	GO:0097193	16	0.016
negative regulation of protein metabolic process	GO:0051248	85	0.016
alternative mrna splicing via spliceosome	GO:0000380	60	0.016
purine ribonucleotide catabolic process	GO:0009154	109	0.016
nucleoside monophosphate metabolic process	GO:0009123	52	0.016
spinal cord development	GO:0021510	1	0.016
cellular respiration	GO:0045333	26	0.016
glycerolipid metabolic process	GO:0046486	34	0.016
negative regulation of developmental process	GO:0051093	201	0.016
cellular catabolic process	GO:0044248	372	0.016
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.016
negative regulation of cell cycle phase transition	GO:1901988	103	0.016
growth	GO:0040007	359	0.016
developmental growth	GO:0048589	280	0.015
tube morphogenesis	GO:0035239	191	0.015
ribonucleotide catabolic process	GO:0009261	109	0.015
regulation of phosphate metabolic process	GO:0019220	210	0.015
response to oxygen levels	GO:0070482	59	0.015
epithelial cell development	GO:0002064	274	0.015	Fly
ovarian follicle cell development	GO:0030707	248	0.015	Fly
negative regulation of cell development	GO:0010721	62	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.015
organic substance catabolic process	GO:1901575	308	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.015
negative regulation of cell differentiation	GO:0045596	143	0.015
post embryonic appendage morphogenesis	GO:0035120	385	0.015
cellular homeostasis	GO:0019725	80	0.015
imaginal disc derived wing morphogenesis	GO:0007476	337	0.015
cellular macromolecule localization	GO:0070727	220	0.015	Fly
establishment of protein localization	GO:0045184	163	0.015
rna processing	GO:0006396	147	0.015
positive regulation of growth	GO:0045927	75	0.015
respiratory system development	GO:0060541	213	0.014
dna metabolic process	GO:0006259	227	0.014
segmentation	GO:0035282	207	0.014	Fly
response to starvation	GO:0042594	97	0.014
mitotic nuclear division	GO:0007067	213	0.014
organophosphate catabolic process	GO:0046434	112	0.014
response to other organism	GO:0051707	293	0.014
organic cyclic compound catabolic process	GO:1901361	168	0.014
regulation of growth	GO:0040008	233	0.014
mapk cascade	GO:0000165	107	0.014
phagocytosis	GO:0006909	215	0.014	Fly
chromosome organization	GO:0051276	360	0.014
synapse assembly	GO:0007416	143	0.014
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.014
organophosphate biosynthetic process	GO:0090407	46	0.014
spermatid differentiation	GO:0048515	114	0.014
negative regulation of apoptotic process	GO:0043066	63	0.014
nucleoside triphosphate catabolic process	GO:0009143	108	0.014
positive regulation of cell differentiation	GO:0045597	64	0.014
regulation of catalytic activity	GO:0050790	185	0.014
protein targeting	GO:0006605	64	0.013
inorganic ion transmembrane transport	GO:0098660	73	0.013
negative regulation of intracellular signal transduction	GO:1902532	57	0.013
regulation of molecular function	GO:0065009	217	0.013
regulation of intracellular signal transduction	GO:1902531	236	0.013
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	11	0.013
mrna metabolic process	GO:0016071	124	0.013
regulation of organelle organization	GO:0033043	196	0.013
detection of external stimulus	GO:0009581	66	0.013
nucleotide catabolic process	GO:0009166	109	0.013
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.013
protein transport	GO:0015031	155	0.013
regulation of cell proliferation	GO:0042127	163	0.013
ribonucleoside catabolic process	GO:0042454	112	0.013
regulation of protein metabolic process	GO:0051246	256	0.013
carbohydrate metabolic process	GO:0005975	82	0.013
energy derivation by oxidation of organic compounds	GO:0015980	32	0.013
single organism membrane organization	GO:0044802	93	0.013
regulation of intracellular transport	GO:0032386	64	0.013
aromatic compound catabolic process	GO:0019439	166	0.013
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.012
regulation of cellular localization	GO:0060341	136	0.012
response to lipopolysaccharide	GO:0032496	4	0.012
hindbrain development	GO:0030902	2	0.012
regulation of establishment of planar polarity	GO:0090175	22	0.012
response to nutrient levels	GO:0031667	114	0.012
microtubule based movement	GO:0007018	51	0.012	Fly
neurological system process	GO:0050877	358	0.012
vesicle mediated transport	GO:0016192	381	0.012	Fly
negative regulation of rna biosynthetic process	GO:1902679	240	0.012
negative regulation of homeostatic process	GO:0032845	2	0.012
regulation of mrna processing	GO:0050684	71	0.012
open tracheal system development	GO:0007424	204	0.012
regulation of circadian rhythm	GO:0042752	49	0.012
l amino acid import	GO:0043092	2	0.012
regulation of mitotic cell cycle	GO:0007346	190	0.012
oxidation reduction process	GO:0055114	123	0.012
response to hypoxia	GO:0001666	53	0.012
cell type specific apoptotic process	GO:0097285	38	0.012
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.011
regulation of cell substrate adhesion	GO:0010810	2	0.011
establishment or maintenance of polarity of follicular epithelium	GO:0016334	26	0.011
positive regulation of gene expression	GO:0010628	290	0.011
pigmentation	GO:0043473	75	0.011
neuron recognition	GO:0008038	101	0.011
cellular lipid metabolic process	GO:0044255	83	0.011
cellular response to radiation	GO:0071478	52	0.011
regulation of epithelial cell proliferation	GO:0050678	4	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.011
regulation of hydrolase activity	GO:0051336	97	0.011
embryo development ending in birth or egg hatching	GO:0009792	152	0.011
long term memory	GO:0007616	62	0.011
organic acid metabolic process	GO:0006082	103	0.011
negative regulation of rna metabolic process	GO:0051253	251	0.011
regulation of mrna metabolic process	GO:1903311	72	0.011
nucleoside phosphate catabolic process	GO:1901292	110	0.011
localization of cell	GO:0051674	257	0.011
ion transmembrane transport	GO:0034220	122	0.011
light induced release of internally sequestered calcium ion	GO:0008377	1	0.011
positive regulation of cell death	GO:0010942	69	0.011
nuclear division	GO:0000280	332	0.011
peripheral nervous system development	GO:0007422	52	0.011
response to bacterium	GO:0009617	198	0.011
oxidative phosphorylation	GO:0006119	9	0.011
regulation of response to stress	GO:0080134	200	0.011
response to organic substance	GO:0010033	284	0.011
carbohydrate derivative catabolic process	GO:1901136	118	0.011
extrinsic apoptotic signaling pathway	GO:0097191	1	0.011
regulation of protein transport	GO:0051223	57	0.011
dephosphorylation	GO:0016311	51	0.011
axis specification	GO:0009798	167	0.011	Fly
negative regulation of stem cell proliferation	GO:2000647	30	0.011
sensory perception of pain	GO:0019233	4	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.011
cellular cation homeostasis	GO:0030003	38	0.011
glycosyl compound catabolic process	GO:1901658	112	0.011
divalent inorganic cation transport	GO:0072511	30	0.010
dorsal ventral axis specification	GO:0009950	66	0.010
wing disc morphogenesis	GO:0007472	344	0.010
cellular amine metabolic process	GO:0044106	12	0.010
cytoskeleton dependent intracellular transport	GO:0030705	44	0.010
protein phosphorylation	GO:0006468	169	0.010
negative regulation of cell death	GO:0060548	81	0.010
translation	GO:0006412	69	0.010
positive regulation of catabolic process	GO:0009896	105	0.010
positive regulation of rna metabolic process	GO:0051254	271	0.010
cation homeostasis	GO:0055080	51	0.010
ubiquitin dependent protein catabolic process	GO:0006511	78	0.010
positive regulation of cellular catabolic process	GO:0031331	95	0.010
positive regulation of apoptotic process	GO:0043065	47	0.010
negative regulation of nervous system development	GO:0051961	92	0.010
chemotaxis	GO:0006935	249	0.010
regulation of lipid metabolic process	GO:0019216	15	0.010
imaginal disc derived appendage development	GO:0048737	399	0.010
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.010
protein catabolic process	GO:0030163	101	0.010
purine ribonucleoside catabolic process	GO:0046130	112	0.010
morphogenesis of follicular epithelium	GO:0016333	36	0.010

CG15173 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.053
nervous system disease	DOID:863	0.042
disease of metabolism	DOID:0014667	0.025
disease of cellular proliferation	DOID:14566	0.021
central nervous system disease	DOID:331	0.021
cancer	DOID:162	0.020
organ system cancer	DOID:0050686	0.020
neurodegenerative disease	DOID:1289	0.020

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