Drosophila melanogaster

78 known processes

Mlf (Dmel_CG8295)

Myelodysplasia/myeloid leukemia factor

(Aliases: MLF,CG8295,dMLF,Dmel\CG8295,BcDNA:SD18148,dmlf)

Mlf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein conjugation or removalGO:00706471060.546
cell deathGO:00082192790.521
regulation of cell cycleGO:00517262910.473
endocytosisGO:00068973100.411
programmed cell deathGO:00125012570.400
deathGO:00162652840.376
positive regulation of cellular component organizationGO:00511301560.354
protein ubiquitinationGO:0016567700.339
positive regulation of rna metabolic processGO:00512542710.252
organic substance catabolic processGO:19015753080.238
vesicle mediated transportGO:00161923810.223
dendrite developmentGO:00163582040.188
intracellular signal transductionGO:00355563000.176
regulation of cellular component biogenesisGO:00440872010.171
positive regulation of gene expressionGO:00106282900.170
embryo development ending in birth or egg hatchingGO:00097921520.164
apoptotic processGO:00069151590.160
neuromuscular junction developmentGO:00075281490.159
heterocycle catabolic processGO:00467001660.157
cellular nitrogen compound catabolic processGO:00442701650.147
cellular macromolecule catabolic processGO:00442651360.144
protein modification by small protein conjugationGO:0032446790.126
negative regulation of apoptotic processGO:0043066630.123
catabolic processGO:00090564090.112
synapse organizationGO:00508081960.107
positive regulation of signal transductionGO:00099672230.104
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573610.102
negative regulation of cell deathGO:0060548810.101
aromatic compound catabolic processGO:00194391660.100
positive regulation of nitrogen compound metabolic processGO:00511733540.098
purine ribonucleotide metabolic processGO:00091501450.093
regulation of localizationGO:00328792750.092
negative regulation of rna metabolic processGO:00512532510.091
phosphorylationGO:00163102940.089
nucleobase containing compound catabolic processGO:00346551650.086
macromolecular complex assemblyGO:00650032560.084
posttranscriptional regulation of gene expressionGO:00106081450.083
cellular catabolic processGO:00442483720.082
positive regulation of cellular biosynthetic processGO:00313283160.081
organonitrogen compound biosynthetic processGO:19015661170.079
establishment of localization in cellGO:00516494020.076
organic acid metabolic processGO:00060821030.075
developmental pigmentationGO:0048066680.069
regulation of cell proliferationGO:00421271630.069
embryonic development via the syncytial blastodermGO:00017001480.069
negative regulation of cell cycleGO:00457861160.068
gland developmentGO:00487321910.068
synaptic transmissionGO:00072682880.066
regulation of phosphate metabolic processGO:00192202100.066
regulation of apoptotic processGO:00429811300.065
oxoacid metabolic processGO:00434361030.064
regulation of transcription from rna polymerase ii promoterGO:00063573780.062
purine ribonucleotide catabolic processGO:00091541090.062
cell proliferationGO:00082832990.060
homeostatic processGO:00425921990.060
negative regulation of programmed cell deathGO:0043069720.060
regulation of cell deathGO:00109411730.059
positive regulation of phosphate metabolic processGO:00459371390.059
positive regulation of transcription dna templatedGO:00458932660.055
regulation of programmed cell deathGO:00430671520.055
transcription from rna polymerase ii promoterGO:00063663680.054
cell cycle checkpointGO:0000075950.051
negative regulation of developmental processGO:00510932010.051
organonitrogen compound metabolic processGO:19015643180.050
regulation of phosphorylationGO:00423251470.050
oocyte microtubule cytoskeleton organizationGO:0016325350.050
protein localization to nucleusGO:0034504550.050
regulation of phosphorus metabolic processGO:00511742100.049
positive regulation of catabolic processGO:00098961050.049
small molecule metabolic processGO:00442813050.048
nucleoside phosphate catabolic processGO:19012921100.048
negative regulation of cell differentiationGO:00455961430.048
cellular protein modification processGO:00064644380.047
regulation of synapse structure and activityGO:00508031280.047
phagocytosisGO:00069092150.047
positive regulation of phosphorus metabolic processGO:00105621390.046
cell divisionGO:00513012480.046
regulation of molecular functionGO:00650092170.043
positive regulation of cellular amine metabolic processGO:003324000.043
membrane organizationGO:00610241120.042
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.042
organophosphate metabolic processGO:00196371950.041
protein localization to organelleGO:0033365820.041
response to external biotic stimulusGO:00432072930.040
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.040
pigmentationGO:0043473750.040
cellular response to dna damage stimulusGO:00069742230.040
ribonucleotide catabolic processGO:00092611090.039
protein modification processGO:00362114380.039
regulation of reproductive processGO:2000241540.038
growthGO:00400073590.037
rna processingGO:00063961470.037
immune system developmentGO:0002520570.036
positive regulation of rna biosynthetic processGO:19026802660.036
regulation of cell developmentGO:00602842150.035
reproductive system developmentGO:0061458740.035
regulation of intracellular signal transductionGO:19025312360.035
hemopoiesisGO:0030097460.035
regulation of synaptic transmissionGO:0050804690.035
nucleus organizationGO:0006997450.035
regulation of transportGO:00510491810.035
positive regulation of programmed cell deathGO:0043068620.035
axis specificationGO:00097981670.035
cellular protein catabolic processGO:0044257830.034
germ line stem cell maintenanceGO:0030718500.033
neurological system processGO:00508773580.032
camera type eye developmentGO:004301040.032
regulation of canonical wnt signaling pathwayGO:0060828150.032
negative regulation of multicellular organismal processGO:00512411420.032
larval developmentGO:00021641040.032
positive regulation of cell deathGO:0010942690.032
cellular macromolecule localizationGO:00707272200.030
macromolecule catabolic processGO:00090571610.030
regulation of mitotic cell cycleGO:00073461900.030
positive regulation of nucleic acid templated transcriptionGO:19035082660.030
eye morphogenesisGO:00485922600.029
appendage developmentGO:00487364010.029
purine nucleotide metabolic processGO:00061631460.029
immune system processGO:00023763470.029
positive regulation of macromolecule metabolic processGO:00106044050.028
nucleoside phosphate metabolic processGO:00067531620.028
positive regulation of nucleobase containing compound metabolic processGO:00459353320.028
ras protein signal transductionGO:0007265880.027
nucleotide metabolic processGO:00091171610.027
connective tissue developmentGO:006144830.026
adult behaviorGO:00305341370.026
secretionGO:00469031090.026
positive regulation of transportGO:0051050920.026
mapk cascadeGO:00001651070.026
stem cell maintenanceGO:0019827670.025
cellular protein localizationGO:00346131600.025
positive regulation of cell communicationGO:00106472500.025
protein targeting to nucleusGO:0044744510.025
regulation of establishment of protein localizationGO:0070201610.025
negative regulation of biosynthetic processGO:00098902770.025
positive regulation of response to stimulusGO:00485843230.024
regulation of mrna 3 end processingGO:003144070.024
purine containing compound catabolic processGO:00725231120.024
negative regulation of cell proliferationGO:0008285690.024
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.024
regulation of wnt signaling pathwayGO:0030111680.024
mitotic dna damage checkpointGO:0044773740.024
positive regulation of apoptotic signaling pathwayGO:200123540.024
regulation of anatomical structure morphogenesisGO:00226032420.024
chondroitin sulfate biosynthetic processGO:003020620.024
cellular response to starvationGO:0009267610.023
regulation of catalytic activityGO:00507901850.022
rhythmic processGO:00485111060.022
negative regulation of response to stimulusGO:00485852580.022
taxisGO:00423303040.022
actin filament based processGO:00300292200.022
signal transduction by phosphorylationGO:00230141070.021
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.021
positive regulation of protein transportGO:0051222370.021
regulation of cellular protein metabolic processGO:00322682430.021
intrinsic apoptotic signaling pathwayGO:0097193160.021
negative regulation of cellular metabolic processGO:00313243820.020
meiotic cytokinesisGO:0033206330.020
negative regulation of rna biosynthetic processGO:19026792400.020
peptidyl amino acid modificationGO:00181931050.020
mitotic g2 m transition checkpointGO:0044818700.020
positive regulation of macromolecule biosynthetic processGO:00105572830.020
negative regulation of cellular protein metabolic processGO:0032269850.019
rna phosphodiester bond hydrolysisGO:0090501170.019
histone modificationGO:00165701060.019
reproductive structure developmentGO:0048608740.019
tissue morphogenesisGO:00487292970.019
small gtpase mediated signal transductionGO:0007264880.019
ribose phosphate metabolic processGO:00196931450.019
purine nucleoside triphosphate metabolic processGO:00091441190.019
apoptotic signaling pathwayGO:0097190270.019
erk1 and erk2 cascadeGO:0070371390.019
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.018
mitotic g2 dna damage checkpointGO:0007095690.018
chromosome organizationGO:00512763600.018
regulation of immune responseGO:00507761180.018
exocrine system developmentGO:00352721620.018
axon cargo transportGO:0008088290.018
regulation of vesicle mediated transportGO:0060627590.018
development of primary sexual characteristicsGO:0045137500.018
single organism biosynthetic processGO:00447112060.017
regulation of endocytosisGO:0030100370.017
organic cyclic compound catabolic processGO:19013611680.017
intracellular transportGO:00469072280.017
regulation of protein complex assemblyGO:0043254420.017
retrograde transport endosome to golgiGO:004214730.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
nucleoside triphosphate metabolic processGO:00091411200.017
positive regulation of signalingGO:00230562430.017
regulation of protein stabilityGO:0031647430.016
purine ribonucleoside catabolic processGO:00461301120.016
positive regulation of molecular functionGO:00440931360.016
nucleoside triphosphate catabolic processGO:00091431080.016
modification dependent macromolecule catabolic processGO:0043632790.016
mitotic cell cycle checkpointGO:0007093880.016
carbohydrate derivative metabolic processGO:19011352170.016
autophagic cell deathGO:0048102830.016
response to endogenous stimulusGO:00097191190.016
carbohydrate metabolic processGO:0005975820.016
purine nucleotide catabolic processGO:00061951090.015
dendrite morphogenesisGO:00488131990.015
regulation of nervous system developmentGO:00519602480.015
chaeta developmentGO:0022416970.015
negative regulation of cell communicationGO:00106482230.015
single organism intracellular transportGO:19025822070.015
cortical cytoskeleton organizationGO:0030865290.015
nuclear transcribed mrna poly a tail shorteningGO:0000289120.015
photoreceptor cell differentiationGO:00465301700.015
eye pigmentationGO:0048069430.014
histone deubiquitinationGO:001657880.014
single organism nuclear importGO:1902593510.014
negative regulation of gene expressionGO:00106293870.014
eye photoreceptor cell developmentGO:0042462810.014
purine nucleoside metabolic processGO:00422781270.014
actin cytoskeleton organizationGO:00300362060.014
hematopoietic progenitor cell differentiationGO:000224410.013
negative regulation of cell cycle processGO:00109481090.013
regulation of protein metabolic processGO:00512462560.013
receptor mediated endocytosisGO:0006898210.013
regulation of cytoplasmic transportGO:1903649470.013
purine containing compound metabolic processGO:00725211550.013
meiotic cell cycle processGO:19030461320.013
membrane disassemblyGO:003039740.013
synapse assemblyGO:00074161430.013
positive regulation of protein catabolic processGO:0045732340.013
cytoplasmic transportGO:00164821300.013
nucleocytoplasmic transportGO:0006913720.013
ribonucleoside metabolic processGO:00091191270.013
regulation of cellular amine metabolic processGO:003323830.013
ion transportGO:00068111450.013
protein catabolic processGO:00301631010.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
nucleoside metabolic processGO:00091161270.012
anterior posterior pattern specificationGO:00099521360.012
regulation of protein ubiquitinationGO:0031396220.012
post embryonic appendage morphogenesisGO:00351203850.012
organelle assemblyGO:00709251980.012
rhabdomere developmentGO:0042052380.012
negative regulation of signal transductionGO:00099682060.012
response to abiotic stimulusGO:00096283410.012
regulation of protein transportGO:0051223570.012
regulation of protein localizationGO:0032880760.012
response to biotic stimulusGO:00096072940.012
regulation of protein modification processGO:00313991120.012
cellular homeostasisGO:0019725800.012
dna damage checkpointGO:0000077780.012
developmental programmed cell deathGO:00106231380.012
regulation of gene expression epigeneticGO:00400291280.012
dna templated transcription elongationGO:0006354180.012
negative regulation of nucleic acid templated transcriptionGO:19035072400.011
vesicle organizationGO:0016050440.011
regulation of protein import into nucleusGO:0042306280.011
negative regulation of immune responseGO:0050777390.011
stem cell developmentGO:0048864790.011
dna amplificationGO:0006277110.011
regulation of cellular localizationGO:00603411360.011
regulation of cellular catabolic processGO:00313291570.011
hematopoietic or lymphoid organ developmentGO:0048534570.011
muscle organ developmentGO:00075171270.011
arf protein signal transductionGO:003201120.011
regulation of multi organism processGO:00439001310.011
regulation of synapse organizationGO:00508071100.011
single organism catabolic processGO:00447122280.011
positive regulation of phosphorylationGO:0042327870.011
axon developmentGO:00615642970.010
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.010
synaptic transmission gabaergicGO:005193210.010
ribonucleoside catabolic processGO:00424541120.010
nucleobase containing small molecule metabolic processGO:00550861740.010
response to other organismGO:00517072930.010
embryonic organ developmentGO:0048568500.010
regulation of multicellular organismal developmentGO:20000264140.010

Mlf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
male reproductive organ cancerDOID:385600.018
reproductive organ cancerDOID:19300.018
cancerDOID:16200.018
organ system cancerDOID:005068600.018
disease of cellular proliferationDOID:1456600.018
musculoskeletal system diseaseDOID:1700.011
disease of anatomical entityDOID:700.011