Drosophila melanogaster

238 known processes

Iap2 (Dmel_CG8293)

Inhibitor of apoptosis 2

(Aliases: Diha,dIAP2,dIAP,dILP,CG8293,IAP2,IAP,DIHA,Dmel\CG8293,D-iap2,Diap,Ilp,D-IAP2,diap2,DIAP2,DIAPII,Diap2,DIAP-2,DIAP)

Iap2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein complex assemblyGO:00064612000.391
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.327
regulation of peptidase activityGO:0052547390.324
regulation of endopeptidase activityGO:0052548360.265
regulation of response to stressGO:00801342000.234
regulation of cellular protein metabolic processGO:00322682430.194
positive regulation of response to stimulusGO:00485843230.186
negative regulation of cellular metabolic processGO:00313243820.169
regulation of protein metabolic processGO:00512462560.147
transmembrane transportGO:00550851390.144
negative regulation of signalingGO:00230572190.137
regulation of programmed cell deathGO:00430671520.137
cell deathGO:00082192790.120
regulation of hydrolase activityGO:0051336970.099
positive regulation of cellular biosynthetic processGO:00313283160.096
regulation of intracellular signal transductionGO:19025312360.090
positive regulation of nitrogen compound metabolic processGO:00511733540.087
intracellular signal transductionGO:00355563000.086
organic substance catabolic processGO:19015753080.085
peptide metabolic processGO:0006518800.085
positive regulation of peptidase activityGO:0010952290.083
deathGO:00162652840.080
positive regulation of multi organism processGO:0043902400.079
apoptotic processGO:00069151590.078
regulation of cell deathGO:00109411730.075
regulation of cysteine type endopeptidase activityGO:2000116270.073
positive regulation of biosynthetic processGO:00098913160.071
immune responseGO:00069552460.069
purine containing compound metabolic processGO:00725211550.067
establishment of localization in cellGO:00516494020.067
central nervous system developmentGO:00074172010.067
catabolic processGO:00090564090.064
spermatid differentiationGO:00485151140.063
positive regulation of response to external stimulusGO:0032103440.060
dendrite developmentGO:00163582040.058
protein localizationGO:00081042840.056
positive regulation of endopeptidase activityGO:0010950260.056
programmed cell deathGO:00125012570.054
phosphorylationGO:00163102940.054
spermatogenesisGO:00072832000.051
macromolecule catabolic processGO:00090571610.051
centrosome organizationGO:00512971630.051
response to bacteriumGO:00096171980.050
positive regulation of nucleobase containing compound metabolic processGO:00459353320.049
positive regulation of transportGO:0051050920.049
cellular homeostasisGO:0019725800.049
cellular amide metabolic processGO:0043603800.049
negative regulation of cell deathGO:0060548810.049
embryo development ending in birth or egg hatchingGO:00097921520.048
posttranscriptional regulation of gene expressionGO:00106081450.048
negative regulation of signal transductionGO:00099682060.047
vesicle mediated transportGO:00161923810.045
negative regulation of cell communicationGO:00106482230.044
organonitrogen compound biosynthetic processGO:19015661170.043
regulation of defense responseGO:00313471020.043
response to biotic stimulusGO:00096072940.042
negative regulation of response to stimulusGO:00485852580.041
positive regulation of macromolecule metabolic processGO:00106044050.041
regulation of cellular response to stressGO:0080135890.041
positive regulation of catalytic activityGO:00430851180.040
positive regulation of signalingGO:00230562430.040
spermatid developmentGO:0007286980.040
positive regulation of cell communicationGO:00106472500.040
regulation of anatomical structure morphogenesisGO:00226032420.039
proteolysisGO:00065081920.039
intracellular transportGO:00469072280.038
single organism membrane organizationGO:0044802930.038
body morphogenesisGO:001017120.038
regulation of molecular functionGO:00650092170.038
spindle organizationGO:00070512530.038
regulation of proteolysisGO:0030162870.037
positive regulation of proteolysisGO:0045862520.036
cellular component disassemblyGO:0022411460.035
cellular catabolic processGO:00442483720.035
positive regulation of signal transductionGO:00099672230.035
positive regulation of defense response to bacteriumGO:1900426230.035
regulation of transcription from rna polymerase ii promoterGO:00063573780.034
single organism cellular localizationGO:19025801800.034
positive regulation of rna metabolic processGO:00512542710.033
aromatic compound catabolic processGO:00194391660.033
organonitrogen compound catabolic processGO:19015651280.032
protein processingGO:0016485680.032
antibacterial humoral responseGO:0019731440.032
positive regulation of immune system processGO:0002684680.032
regulation of innate immune responseGO:0045088710.032
regulation of phosphorus metabolic processGO:00511742100.032
antibacterial peptide biosynthetic processGO:0002780220.031
melanization defense responseGO:0035006450.031
small molecule metabolic processGO:00442813050.031
single organism catabolic processGO:00447122280.031
single organism intracellular transportGO:19025822070.031
regulation of immune responseGO:00507761180.031
regulation of cell cycleGO:00517262910.031
intracellular protein transportGO:00068861040.031
guanosine containing compound catabolic processGO:1901069740.031
cellular macromolecule catabolic processGO:00442651360.031
positive regulation of cellular protein metabolic processGO:00322701180.030
cellular nitrogen compound catabolic processGO:00442701650.030
negative regulation of apoptotic processGO:0043066630.029
homeostatic processGO:00425921990.029
antibacterial peptide productionGO:0002778220.029
macromolecular complex assemblyGO:00650032560.029
positive regulation of cell deathGO:0010942690.029
forebrain developmentGO:003090020.028
positive regulation of immune responseGO:0050778630.028
purine nucleoside metabolic processGO:00422781270.028
protein modification processGO:00362114380.028
microtubule organizing center organizationGO:00310231680.028
compound eye developmentGO:00487493070.027
dendrite morphogenesisGO:00488131990.027
regulation of catalytic activityGO:00507901850.027
chromosome organizationGO:00512763600.027
compound eye morphogenesisGO:00017452490.027
cellular protein modification processGO:00064644380.027
jak stat cascadeGO:0007259490.026
heterocycle catabolic processGO:00467001660.026
positive regulation of programmed cell deathGO:0043068620.026
negative regulation of endopeptidase activityGO:0010951110.026
positive regulation of nucleic acid templated transcriptionGO:19035082660.025
regulation of immune system processGO:00026821760.025
cell proliferationGO:00082832990.025
single organism behaviorGO:00447083910.024
endomembrane system organizationGO:00102561190.024
immune system processGO:00023763470.024
regulation of multi organism processGO:00439001310.024
positive regulation of protein metabolic processGO:00512471280.024
mitochondrion organizationGO:0007005650.024
positive regulation of apoptotic processGO:0043065470.024
defense response to gram negative bacteriumGO:0050829940.023
regulation of apoptotic processGO:00429811300.023
cell migrationGO:00164772380.023
nucleoside phosphate metabolic processGO:00067531620.023
enzyme linked receptor protein signaling pathwayGO:00071671790.023
male gamete generationGO:00482322010.023
embryonic development via the syncytial blastodermGO:00017001480.022
positive regulation of intracellular signal transductionGO:19025331160.022
microtubule based transportGO:0010970420.022
defense response to bacteriumGO:00427421780.022
purine ribonucleoside metabolic processGO:00461281270.022
regulation of phosphorylationGO:00423251470.021
organic hydroxy compound metabolic processGO:1901615830.021
negative regulation of biosynthetic processGO:00098902770.021
defense responseGO:00069523000.021
cellular macromolecular complex assemblyGO:00346221530.021
cation transportGO:00068121100.021
actin cytoskeleton organizationGO:00300362060.021
response to radiationGO:00093141550.021
ovarian follicle cell developmentGO:00307072480.021
cell cell signaling involved in cell fate commitmentGO:00451682100.020
regulation of mapk cascadeGO:0043408920.020
positive regulation of hydrolase activityGO:0051345780.020
negative regulation of gene expressionGO:00106293870.020
mapk cascadeGO:00001651070.020
ion transportGO:00068111450.020
melanin metabolic processGO:0006582470.020
positive regulation of phosphorus metabolic processGO:00105621390.019
cell divisionGO:00513012480.019
protein complex biogenesisGO:00702712010.019
macromolecular complex disassemblyGO:0032984370.019
endocytosisGO:00068973100.019
nucleobase containing compound catabolic processGO:00346551650.019
regulation of organelle organizationGO:00330431960.019
protein catabolic processGO:00301631010.019
positive regulation of multicellular organismal processGO:00512401430.019
ion transmembrane transportGO:00342201220.019
immune system developmentGO:0002520570.019
chaeta developmentGO:0022416970.019
positive regulation of developmental processGO:00510941430.019
organic cyclic compound catabolic processGO:19013611680.019
developmental programmed cell deathGO:00106231380.019
appendage morphogenesisGO:00351073970.018
intracellular protein transmembrane transportGO:006500240.018
protein modification by small protein conjugation or removalGO:00706471060.018
establishment of protein localizationGO:00451841630.018
metal ion homeostasisGO:0055065440.018
male mating behaviorGO:0060179700.018
protein transmembrane transportGO:007180640.018
positive regulation of macromolecule biosynthetic processGO:00105572830.018
immune effector processGO:0002252980.018
cell motilityGO:00488702510.018
protein modification by small protein conjugationGO:0032446790.017
nucleus organizationGO:0006997450.017
metal ion transportGO:0030001740.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.017
organonitrogen compound metabolic processGO:19015643180.017
purine ribonucleoside catabolic processGO:00461301120.017
chromatin organizationGO:00063252070.017
pigment metabolic processGO:0042440840.017
carboxylic acid metabolic processGO:0019752920.017
regulation of vesicle mediated transportGO:0060627590.016
regulation of cellular amine metabolic processGO:003323830.016
embryonic morphogenesisGO:00485982060.016
innate immune responseGO:00450871440.016
regulation of cell shapeGO:00083601130.016
regulation of transportGO:00510491810.016
appendage developmentGO:00487364010.016
protein localization to organelleGO:0033365820.016
positive regulation of apoptotic signaling pathwayGO:200123540.016
transcription from rna polymerase ii promoterGO:00063663680.016
regulation of catabolic processGO:00098941700.016
peptidyl amino acid modificationGO:00181931050.016
regulation of execution phase of apoptosisGO:190011750.015
establishment of organelle localizationGO:00516561220.015
regulation of antibacterial peptide biosynthetic processGO:0002808220.015
brain developmentGO:00074201200.015
purine nucleoside catabolic processGO:00061521120.015
protein maturationGO:0051604710.015
positive regulation of gene expressionGO:00106282900.015
cytoskeleton dependent intracellular transportGO:0030705440.015
amide biosynthetic processGO:0043604420.015
oxoacid metabolic processGO:00434361030.015
negative regulation of intracellular signal transductionGO:1902532570.015
eye morphogenesisGO:00485922600.015
tissue morphogenesisGO:00487292970.014
regulation of protein modification processGO:00313991120.014
translationGO:0006412690.014
microtubule based movementGO:0007018510.014
mitotic cell cycle phase transitionGO:00447721380.014
regulation of production of molecular mediator of immune responseGO:0002700440.014
centrosome duplicationGO:00512981210.014
regulation of immune effector processGO:0002697520.014
response to other organismGO:00517072930.014
mitochondrion morphogenesisGO:007058480.014
cellular metal ion homeostasisGO:0006875310.014
regulation of protein processingGO:0070613320.014
negative regulation of phosphate metabolic processGO:0045936450.014
regulation of multicellular organismal developmentGO:20000264140.013
glycosyl compound metabolic processGO:19016571270.013
regulation of phosphate metabolic processGO:00192202100.013
regulation of mitotic cell cycle phase transitionGO:19019901300.013
ribose phosphate metabolic processGO:00196931450.013
ameboidal type cell migrationGO:00016671510.013
cellular macromolecule localizationGO:00707272200.013
organelle fissionGO:00482853400.013
nucleoside triphosphate catabolic processGO:00091431080.013
response to abiotic stimulusGO:00096283410.013
reactive oxygen species metabolic processGO:0072593220.013
nucleobase containing small molecule metabolic processGO:00550861740.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
regulation of cellular localizationGO:00603411360.013
negative regulation of mitotic cell cycle phase transitionGO:19019911030.013
positive regulation of cellular catabolic processGO:0031331950.013
response to organic substanceGO:00100332840.013
carbohydrate derivative catabolic processGO:19011361180.012
response to external biotic stimulusGO:00432072930.012
signal transduction by phosphorylationGO:00230141070.012
positive regulation of cysteine type endopeptidase activityGO:2001056240.012
negative regulation of cell cycle phase transitionGO:19019881030.012
peptide biosynthetic processGO:0043043420.012
ribonucleoside metabolic processGO:00091191270.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
negative regulation of proteolysisGO:0045861310.012
determination of adult lifespanGO:00083401370.012
negative regulation of protein metabolic processGO:0051248850.012
nucleoside triphosphate metabolic processGO:00091411200.012
development of primary sexual characteristicsGO:0045137500.012
positive regulation of production of molecular mediator of immune responseGO:0002702280.012
purine ribonucleotide metabolic processGO:00091501450.012
positive regulation of wnt signaling pathwayGO:0030177250.012
positive regulation of defense responseGO:0031349590.012
adult behaviorGO:00305341370.012
protein acetylationGO:0006473390.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
antimicrobial humoral responseGO:0019730990.012
protein secretionGO:0009306450.012
carbohydrate derivative metabolic processGO:19011352170.011
purine containing compound catabolic processGO:00725231120.011
positive regulation of antibacterial peptide productionGO:0002803200.011
salivary gland morphogenesisGO:00074351450.011
regulation of cell proliferationGO:00421271630.011
localization of cellGO:00516742570.011
positive regulation of molecular functionGO:00440931360.011
regulation of translationGO:0006417560.011
developmental maturationGO:00217001720.011
epithelium migrationGO:00901321480.011
cellular amino acid metabolic processGO:0006520610.011
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.011
negative regulation of molecular functionGO:0044092510.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
hematopoietic or lymphoid organ developmentGO:0048534570.011
mitotic spindle organizationGO:00070522200.011
gland developmentGO:00487321910.011
nucleoside catabolic processGO:00091641120.011
regulation of antibacterial peptide productionGO:0002786220.011
positive regulation of cellular amine metabolic processGO:003324000.011
stress activated protein kinase signaling cascadeGO:0031098550.011
spindle assemblyGO:0051225800.011
protein ubiquitinationGO:0016567700.011
antimicrobial peptide biosynthetic processGO:0002777380.011
membrane organizationGO:00610241120.011
regulation of cellular catabolic processGO:00313291570.011
negative regulation of mitotic cell cycleGO:00459301090.011
regulation of localizationGO:00328792750.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
morphogenesis of an epitheliumGO:00020092760.011
phagocytosisGO:00069092150.011
chaeta morphogenesisGO:0008407420.011
regulation of organ morphogenesisGO:2000027780.010
protein transportGO:00150311550.010
positive regulation of cellular component organizationGO:00511301560.010
negative regulation of phosphorus metabolic processGO:0010563450.010
tissue deathGO:00162711020.010
developmental growthGO:00485892800.010
nephron developmentGO:007200630.010
gtp metabolic processGO:0046039720.010
translational elongationGO:000641440.010
protein modification by small protein removalGO:0070646280.010
cell cycle phase transitionGO:00447701400.010
negative regulation of cellular protein metabolic processGO:0032269850.010
protein polymerizationGO:0051258420.010
positive regulation of rna biosynthetic processGO:19026802660.010

Iap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
nervous system diseaseDOID:86300.028
central nervous system diseaseDOID:33100.028