IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG12379 (Dmel_CG12379)

CG12379 gene product from transcript CG12379-RB

(Aliases: Dmel\CG12379)

FLYBASE: FBgn0030676
Entrez: 32512
UniProtKB: Q9VXR1

Process Predictions
Disease Predictions

CG12379 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
establishment of localization in cell	GO:0051649	402	0.108	Yeast
response to temperature stimulus	GO:0009266	106	0.102
catabolic process	GO:0009056	409	0.090
cellular catabolic process	GO:0044248	372	0.090
protein localization	GO:0008104	284	0.080	Yeast
organic cyclic compound catabolic process	GO:1901361	168	0.066
organic substance transport	GO:0071702	257	0.062	Yeast
dna metabolic process	GO:0006259	227	0.061
single organism intracellular transport	GO:1902582	207	0.061	Yeast
cellular protein localization	GO:0034613	160	0.057	Yeast
vesicle mediated transport	GO:0016192	381	0.049
single organism cellular localization	GO:1902580	180	0.049	Yeast
organonitrogen compound metabolic process	GO:1901564	318	0.048
negative regulation of cellular metabolic process	GO:0031324	382	0.047
single organism catabolic process	GO:0044712	228	0.045
regulation of organelle organization	GO:0033043	196	0.043
positive regulation of cell communication	GO:0010647	250	0.041
small molecule metabolic process	GO:0044281	305	0.041
endocytosis	GO:0006897	310	0.040
heterocycle catabolic process	GO:0046700	166	0.039
organophosphate metabolic process	GO:0019637	195	0.039
organic substance catabolic process	GO:1901575	308	0.036
aromatic compound catabolic process	GO:0019439	166	0.036
cellular macromolecule localization	GO:0070727	220	0.034	Yeast
intracellular transport	GO:0046907	228	0.033	Yeast
purine ribonucleotide metabolic process	GO:0009150	145	0.032
nucleobase containing compound catabolic process	GO:0034655	165	0.031
nucleobase containing small molecule metabolic process	GO:0055086	174	0.030
regulation of protein metabolic process	GO:0051246	256	0.030
positive regulation of response to stimulus	GO:0048584	323	0.030
ribonucleotide metabolic process	GO:0009259	145	0.029
phagocytosis	GO:0006909	215	0.029
positive regulation of cellular biosynthetic process	GO:0031328	316	0.028
regulation of response to stress	GO:0080134	200	0.028
nucleoside phosphate metabolic process	GO:0006753	162	0.028
protein transport	GO:0015031	155	0.027	Yeast
establishment of protein localization	GO:0045184	163	0.027	Yeast
intracellular signal transduction	GO:0035556	300	0.027
regulation of localization	GO:0032879	275	0.026
death	GO:0016265	284	0.026
positive regulation of signaling	GO:0023056	243	0.026
immune system process	GO:0002376	347	0.026
cytoplasmic transport	GO:0016482	130	0.026	Yeast
organonitrogen compound biosynthetic process	GO:1901566	117	0.025
nucleotide metabolic process	GO:0009117	161	0.025
cellular nitrogen compound catabolic process	GO:0044270	165	0.025
purine nucleotide metabolic process	GO:0006163	146	0.024
lateral inhibition	GO:0046331	206	0.023
growth	GO:0040007	359	0.023
regulation of cell cycle process	GO:0010564	181	0.023
regulation of cell cycle	GO:0051726	291	0.022
mrna metabolic process	GO:0016071	124	0.022
oxoacid metabolic process	GO:0043436	103	0.022
phospholipid homeostasis	GO:0055091	1	0.022
regulation of defense response	GO:0031347	102	0.022
rna processing	GO:0006396	147	0.021
intracellular protein transmembrane transport	GO:0065002	4	0.021	Yeast
response to external biotic stimulus	GO:0043207	293	0.021
regulation of innate immune response	GO:0045088	71	0.020
transmembrane transport	GO:0055085	139	0.020	Yeast
developmental growth	GO:0048589	280	0.020
defense response to other organism	GO:0098542	225	0.019
protein targeting	GO:0006605	64	0.019	Yeast
response to abiotic stimulus	GO:0009628	341	0.019
regulation of programmed cell death	GO:0043067	152	0.019
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.019
ribose phosphate metabolic process	GO:0019693	145	0.019
regulation of transport	GO:0051049	181	0.019
regulation of cell death	GO:0010941	173	0.019
cellular response to dna damage stimulus	GO:0006974	223	0.018
sensory perception of mechanical stimulus	GO:0050954	72	0.018
mitochondrion organization	GO:0007005	65	0.018	Yeast
transcription from rna polymerase ii promoter	GO:0006366	368	0.018
programmed cell death	GO:0012501	257	0.018
nucleotide catabolic process	GO:0009166	109	0.018
homeostatic process	GO:0042592	199	0.017
intracellular protein transport	GO:0006886	104	0.017	Yeast
spindle organization	GO:0007051	253	0.017
purine containing compound metabolic process	GO:0072521	155	0.017
mrna splicing via spliceosome	GO:0000398	73	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.017
rna splicing via transesterification reactions	GO:0000375	73	0.017
negative regulation of gene expression	GO:0010629	387	0.016
response to other organism	GO:0051707	293	0.016
regionalization	GO:0003002	416	0.016
amine metabolic process	GO:0009308	12	0.016
macromolecule catabolic process	GO:0009057	161	0.016
response to nutrient levels	GO:0031667	114	0.016
cellular macromolecule catabolic process	GO:0044265	136	0.016
positive regulation of hydrolase activity	GO:0051345	78	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.016
cellular cation homeostasis	GO:0030003	38	0.016
cellular amine metabolic process	GO:0044106	12	0.015
cell death	GO:0008219	279	0.015
positive regulation of intracellular signal transduction	GO:1902533	116	0.015
purine ribonucleoside metabolic process	GO:0046128	127	0.015
regulation of hydrolase activity	GO:0051336	97	0.015
cation transport	GO:0006812	110	0.015
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.015
positive regulation of molecular function	GO:0044093	136	0.015
gland development	GO:0048732	191	0.015
response to biotic stimulus	GO:0009607	294	0.015
organonitrogen compound catabolic process	GO:1901565	128	0.014
negative regulation of response to stimulus	GO:0048585	258	0.014
positive regulation of phosphorus metabolic process	GO:0010562	139	0.014
membrane organization	GO:0061024	112	0.014
ion homeostasis	GO:0050801	55	0.014
dendrite development	GO:0016358	204	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.014
regulation of growth	GO:0040008	233	0.014
positive regulation of programmed cell death	GO:0043068	62	0.014
mrna catabolic process	GO:0006402	33	0.014
carbohydrate derivative biosynthetic process	GO:1901137	85	0.014
nucleoside triphosphate metabolic process	GO:0009141	120	0.014
cell cycle checkpoint	GO:0000075	95	0.014
cholesterol homeostasis	GO:0042632	3	0.014
dendrite morphogenesis	GO:0048813	199	0.014
cell fate determination	GO:0001709	91	0.013
cellular transition metal ion homeostasis	GO:0046916	9	0.013
cellular metal ion homeostasis	GO:0006875	31	0.013
positive regulation of catabolic process	GO:0009896	105	0.013
protein transmembrane transport	GO:0071806	4	0.013	Yeast
positive regulation of biosynthetic process	GO:0009891	316	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.013
wing disc morphogenesis	GO:0007472	344	0.013
proteolysis	GO:0006508	192	0.013
response to bacterium	GO:0009617	198	0.013
body morphogenesis	GO:0010171	2	0.013
sterol homeostasis	GO:0055092	4	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.012
defense response	GO:0006952	300	0.012
chromatin modification	GO:0016568	147	0.012
protein complex biogenesis	GO:0070271	201	0.012
sensory perception	GO:0007600	196	0.012
male gamete generation	GO:0048232	201	0.012
regulation of catalytic activity	GO:0050790	185	0.012
inorganic ion transmembrane transport	GO:0098660	73	0.012
organophosphate catabolic process	GO:0046434	112	0.012
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.012
ion transport	GO:0006811	145	0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.012
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.012
head development	GO:0060322	135	0.012
regulation of immune response	GO:0050776	118	0.012
adult behavior	GO:0030534	137	0.012
negative regulation of programmed cell death	GO:0043069	72	0.011
positive regulation of phosphate metabolic process	GO:0045937	139	0.011
negative regulation of cellular component organization	GO:0051129	108	0.011
cell cycle phase transition	GO:0044770	140	0.011
ribonucleoside metabolic process	GO:0009119	127	0.011
chromatin organization	GO:0006325	207	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.011
developmental maturation	GO:0021700	172	0.011
rna transport	GO:0050658	46	0.011
positive regulation of transport	GO:0051050	92	0.011
histone modification	GO:0016570	106	0.011
immune response	GO:0006955	246	0.011
purine nucleoside catabolic process	GO:0006152	112	0.011
regulation of apoptotic process	GO:0042981	130	0.011
dorsal ventral pattern formation	GO:0009953	133	0.011
maintenance of location	GO:0051235	73	0.011
negative regulation of signaling	GO:0023057	219	0.011
positive regulation of macromolecule metabolic process	GO:0010604	405	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.011
cellular response to chemical stimulus	GO:0070887	199	0.011
cellular amino acid metabolic process	GO:0006520	61	0.011
response to oxygen containing compound	GO:1901700	200	0.010
chromosome organization	GO:0051276	360	0.010
regulation of cellular protein metabolic process	GO:0032268	243	0.010
cellular iron ion homeostasis	GO:0006879	3	0.010
carbohydrate derivative metabolic process	GO:1901135	217	0.010
single organism membrane organization	GO:0044802	93	0.010
chromatin silencing	GO:0006342	76	0.010
segmentation	GO:0035282	207	0.010
negative regulation of mitotic cell cycle	GO:0045930	109	0.010
response to heat	GO:0009408	63	0.010
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.010

CG12379 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.045
lipid metabolism disorder	DOID:3146	0.045
familial hypertriglyceridemia	DOID:0050527	0.045
inherited metabolic disorder	DOID:655	0.045
disease of anatomical entity	DOID:7	0.032
integumentary system disease	DOID:16	0.025
hair disease	DOID:421	0.025
hypotrichosis	DOID:4535	0.025
nervous system disease	DOID:863	0.015
glucose metabolism disease	DOID:4194	0.011
diabetes mellitus	DOID:9351	0.011
acquired metabolic disease	DOID:0060158	0.011
carbohydrate metabolism disease	DOID:0050013	0.011
type 2 diabetes mellitus	DOID:9352	0.011

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